Search Results (123)

This paper presents the results of an integrated research and design process developed within the Master’s study programme in Architecture at the University of Belgrade—Faculty of Architecture, aimed at exploring architectural agency in conditions of ecological degradation, declining biodiversity, and the urgent need for regenerative transformation of the built environment. Moving beyond technologically driven notions of “green design,” the study investigates architectural approaches that support ecosystem restoration, biodiversity enhancement, and multispecies coexistence while strengthening health and well-being. Grounded in a three-phase methodological framework, the research (1) formulates conceptual models of therapeutic landscapes through typo-morphological, place-based, and adventure-based analytical approaches; (2) evaluates these models using the New European Bauhaus (NEB) Checklist to assess their alignment with the core values of sustainability, beauty, and togetherness; and (3) synthesizes the findings into regenerative design scenarios that integrate ecological processes, multisensory experience, and community participation. The results position therapeutic landscapes as a spatial practice in which architecture functions as ecological infrastructure, a metabolic system where natural cycles, cultural meanings, bodily experiences, and more-than-human agencies interact. In this sense, architectural design becomes the basis for re-naturalization, regeneration, ecological care, multisensory experience, and resilience in urban, peri-urban, and rural communities. Full article

This article reexamines the gold necklace excavated from the Sui-dynasty tomb of Li Jingxun (李静训, 600–608 CE), shifting attention from stylistic attribution to ritual function and funerary context. While previous studies have emphasized Persian, Byzantine, or Indian influences, this study situates the necklace more plausibly within the Iranian–steppe cultural sphere and the Turkic–Sogdian exchange networks active along the Silk Roads in the late sixth and early seventh centuries. Through analysis of its segmented structure, polyhedral gold beads, pearl rondelle, nicolo intaglio clasp, and gemstone arrangement, the article identifies close technical and visual parallels in Central Asia and the wider Iranian world. The necklace is interpreted as an apotropaic object likely worn in life and placed in the tomb to extend its protective and guiding functions after death. Attention to bodily use, clasp orientation, and associated grave goods—especially a stemmed cup with Eurasian ritual associations—clarifies how the necklace operated within a Buddhist burial setting timed to Lichun 立春 (Beginning of Spring). Situating the object within the Li family’s Xianbei 鲜卑 background and documented connections with Sogdian communities, this study demonstrates how foreign ornaments were actively understood and integrated into Sui aristocratic funerary practice, rather than adopted as passive luxuries. Full article

China’s rapid urbanization has created the world’s largest internal migration, increasingly shaped by women’s participation. Co-migrant mothers—rural women who bring their children to cities—occupy complex roles as workers, wives, and caregivers. Existing studies focus on left-behind mothers or individual coping, but little is known about how co-migrant mothers collectively reshape motherhood through urban spatial and social change. Based on fieldwork in a Guangzhou migrant community, this study develops the “disembedding–re-embedding–reconstruction” framework to show how mobility reconfigures motherhood. Moving from villages to cities disembeds mothers from the moral surveillance that enforces self-sacrificing norms. Community-based organizations (CBOs) then serve as re-embedding sites where women form new maternal subjectivities through mutual support and reflection, producing a locally rooted idea of self-caring motherhood. This idea reframes care as reciprocal rather than self-depleting and affirms mothers’ emotional and bodily well-being as part of family life. Finally, these values are reconstructed in households through subtle temporal and spatial negotiations that adjust gendered divisions of labor without open conflict. Highlighting collective empowerment and spatial transformation, this study moves motherhood research beyond individualized lenses and reveals grounded, pragmatic forms of gendered agency in China’s rural–urban migration. Full article

Endometriosis is a common gynecological pathology, with an incidence of nearly 10% in patients of reproductive age, and is still underdiagnosed. A thorough and well-spread diagnostic study of endometriosis based on epigenetic factor dysregulation can highlight potential areas for improvement. To quantify the potential and utility of non-invasive tools in the early diagnosis of endometriosis, an overview of current knowledge on epigenetic factors, based on DNA and RNA, is presented. Among these tools, it is important to highlight the role of miRNAs (microRNAs), cfDNA (cell-free DNA), and rRNAs (ribosomal RNAs), which are small molecules involved in endometriosis and numerous other pathologies. To evaluate their potential and utility in endometriosis, a salivary miRNA diagnostic test was conducted, the cfDNA methylation patterns of fragmented DNA circulating in bodily fluids (e.g., plasma) were analyzed, and cervical and uterine microbiomes were profiled for bacterial rRNA in patients with clinical suspicion of incipient endometriosis. Specific molecular profiles associated with endometriosis were analyzed. The first profile, a 109-miRNA saliva signature, was validated as a product of miRNA biomarkers and artificial intelligence modeling. In addition, peripheral blood cfDNA methylation biomarkers were identified by investigating nine genes in a molecular signature that requires validation. A profile was also obtained from cervical swabs and uterine washes, including molecular analysis of 16S rRNA amplicon sequencing to evaluate alterations in the cervical bacterial community. This review aims to optimize the integration of a non-invasive diagnostic tool for early endometriosis diagnosis. Genetic biomarkers can be correlated with clinical factors to improve diagnostic accuracy. Of the assessed diagnostic tools, salivary miRNA tests, a peripheral blood cfDNA methylation biomarker, and a microbiome rRNA signature may be useful for early diagnosis of endometriosis, as well as, implicitly, therapeutic attitude and follow-up. Full article

This perspective advances a psychoanalytic—embodiment account of the “libido of generativity” (LoG)—future-oriented reorganization of erotic desire that links embodied arousal with caregiving, legacy, and shared projects. We define LoG along four axes (direction of investment: dyad↔triad; temporal horizon: immediacy↔future; outcome modalities: procreative, creative–sublimative, community-forming; affective regulation: shame/guilt↔pride/gratitude). Integrating interoception, body ownership/agency, and self-compassion with reproductive mentalizing, we specify three proximal levers—embodiment, affect regulation, and representation—through which sexual mindfulness can recalibrate bodily salience, blunt shame-based self-objectification, and expand triadic representations (self–partner–child/symbolic offspring). We then translate these mechanisms into a brief, practice-ready relationship guidance (RG) curriculum (6–8 sessions) combining somatic mindfulness, compassion micro-practices, reproductive-mentalizing dialogs, communication skills, and generative rituals. We articulate falsifiable propositions (e.g., mindfulness → ↑couple satisfaction via ↓body-image self-consciousness and ↑reproductive mentalizing) and a sex/gender-attentive reporting plan (SAGER). Primary outcomes include sexual functioning/satisfaction and couple satisfaction/communication; secondary mechanistic endpoints index interoceptive accuracy/awareness (including heartbeat-evoked potentials), self-compassion, and reproductive mentalizing. By aligning contemplative practices with couple-skills training and equity-focused implementation, the LoG framework offers a testable bridge from psychoanalytic theory and embodiment science to measurable improvements in sexual health and couple well-being. Full article

Holy Week, the most significant period of the Christian liturgical year, was marked by solemn and complex rituals enacted within the sacred spaces of medieval religious communities. In the case of Cistercian female monasteries, scholarly attention has largely centered on Easter dramatic representations such as the Depositio or the Visitatio Sepulchri, while the official liturgy—Hours, Masses, processions, and the official rituals of the Easter Triduum—has remained comparatively understudied. This article addresses that gap by examining the Holy Week liturgy as performed by the Cistercian nuns of Lichtenthal (Baden-Baden, Germany), on the basis of an exceptional and understudied source: the original Ecclesiastica Officia (mid-13th century, Karlsruhe, Badisches Generallandesarchiv, 65/323). Containing comprehensive normative prescriptions for the Easter liturgy adapted for the Lichtenthal community, this manuscript enables a detailed reconstruction of the nuns’ primary collective experiences during these days. The study brings together evidence from architecture, works of art, and liturgical books, while integrating insights from sensory studies, in order to underscore the bodily and multi-sensory dimensions of the rituals. In doing so, it highlights the implications of the nuns’ active participation in Holy Week ceremonies and contributes to a deeper understanding of medieval female religious ritual experience, challenging conventional notions of enclosure and liturgical practice. Full article

Background: Performance-enhancing drug (PED) use has become increasingly prevalent among adolescents and emerging adults, not solely for athletic advantage but as a psychological and sociocultural coping mechanism. In Türkiye, where Westernized body ideals intersect with traditional values, the emotional and symbolic meanings of PED use among youth remain underexplored. Methods: This qualitative study employed semi-structured interviews and reflexive thematic analysis to examine the subjective experiences of 26 Turkish adolescents and emerging adults (19 males, 7 females; ages 16–22) in Istanbul who reported non-medical use of steroids or other PEDs. Participants were recruited through snowball sampling in gym-adjacent communities across six urban districts. Interviews were conducted online, recorded, transcribed, and analyzed to identify emergent psychological themes. Results: Six interconnected themes were identified: (1) body-based insecurity and the fantasy of reinvention; (2) emotional regulation through bodily control; (3) secrecy as autonomy; (4) compulsive enhancement and dissatisfaction; (5) psychological dependency and regret; and (6) PED use as agency and protest. While male and female participants differed in aesthetic goals and social narratives, both groups framed PED use as a means of identity construction, emotional survival, and social validation. Participants did not perceive themselves as deviant but as strategic actors navigating a performance-driven culture. Conclusions: PED use among youth in urban Türkiye emerges as a psychologically embedded coping mechanism rooted in emotional regulation, self-concept, and perceived control. Rather than a deviant behavior, it reflects an adaptive but precarious strategy for managing insecurity and achieving recognition during a critical developmental stage. Full article

In recent years, the scientific community has increasingly delved into the study of the interaction between the nervous system and tumors, revealing that the nervous system not only regulates bodily functions under physiological conditions, but also assumes a vital part in the emergence and progression of tumors. Research has demonstrated that the extensive neural network directly regulates tumor progression and can influence tumors by modulating the tumor microenvironment and immune system. Moreover, tumors induce neural networks to provide favorable conditions for their proliferation and metastasis. In the above process, neurotransmitters play a vital role. They directly act or bind to their receptor, activating various classical signaling pathways, among which are PI3K/AKT, MEK/ERK, and WNT/β-catenin, to facilitate tumor advancement. Therefore, this study systematically reviews the regulatory mechanisms of neurotransmitters and their receptors in the advancement of cancer, along with the utilization of targeted drugs. At the same time, we also analyzed that targeting specific receptor subtypes may produce more significant therapeutic effects in different types of cancer. Additionally, this research further explores the limitations of neurotransmitter-based drugs currently used in clinical cancer treatment. In summary, the field of cancer neuroscience is rapidly advancing, constantly revealing the regulatory effects of neurotransmitters on tumor progression and their specific molecular mechanisms, providing broad application prospects for future clinical therapy. Full article

Water is the source of life and also the lifeline of cities. The reconstruction of secondary water supply systems is a key component of urban renewal reforms, and the collaborative governance of such projects has become a focal topic through academic research. In this article, we try to discover the path to successful “bottom-up” collaborative water governance with Collins’s theory of interaction ritual chains (IRC) through a case study of a secondary water supply reconstruction program in J Estate, Jinshan District, Shanghai. The case study involved a total of 104 households, and we employed convenience sampling for all households through door-to-door inquiries, which included semi-structured interviews and non-participant observations. A total of 15 households participated in our interview. This study demonstrates that repeated social interactive rituals, such as bodily co-presence, rhythmic synchronization, and shared signs, can stimulate the accumulation of residents’ emotional energy, which becomes the initial power to promote community water governance and, in return, becomes the driving force for sustained collective action and mutual trust. Drawing on Collins’s theory of IRC, this article fills a gap by explaining the symbolic mechanism driven by emotions and personal relationships that macro-level governance ignores. We also demonstrate the spillover effects of such social rituals and propose policy recommendations that governments should apply, using these rituals to mobilize and consolidate residents’ emotions to create a virtuous circle of collaborative governance. Full article

Background: Children with Autism often face motor, sensory and communicational challenges that can hinder their participation in meaningful physical and social activities. This study explores the potential of Capoeira to support their development across these domains. Methods: This qualitative pilot study used semi-structured interviews with parents of children aged 7–15 with Autism Spectrum Disorder (ASD) who participated in group Capoeira programs. Data were analyzed through content categorization, leading to the development of thematic constructs. Results: Three central domains emerged regarding the perceived impact of Capoeira training on children with Autism: 1. Improvements in areas commonly affected in Autism, including sensory and auditory regulation, motor coordination, bodily awareness, compliance, and social communication. 2. Increased motivation, independence, sense of belonging and integration into mixed peer groups of typically developing (TD) children and children with ASD. 3. Broader developmental gains were also reported, such as increased self-confidence, initiative, awareness of others, and transfer of skills beyond the training context. Conclusions: The findings suggest that Capoeira may serve as an effective integrated intervention model, supporting physical and social development in children with ASD. Capoeira was reported to be associated with improved coordination, balance, body awareness, and gains in nonverbal interaction and social engagement, all within a collaborative, non-competitive framework. Future studies should explore the short and long-term impact of such interventions through quantitative outcome measures, as well as clarify the mechanisms that promote successful integration. Full article

Depression is one of the most disabling of all disorders across the community, yet many aspects of the disorder remain contentious. Psychosocial and biological perspectives are often placed in opposition to one another, which in part reflects a failure of our explanatory frameworks. The active inference account of brain function breaks down this dualism, demonstrating that bodily processes are deeply integrated with the social world. It shows us that there is no contradiction in understanding depression as a product of the social environment at the same time as having a brain basis and manifesting in biological symptoms. From an active inference perspective, depression can be thought of as a synaptopathy: a disorder that arises from alterations to the excitatory-inhibitory balance enacted at the synapse, reflecting the interoceptive precision-weightings that have changed in the context of psychosocial instability. Therapies that alleviate depressive symptoms act at different levels of the active inference framework to re-weight precision estimates and the confidence we have in our predictions: this is true for psychotherapies, lifestyle interventions and antidepressant medications. Their effectiveness is often only partial, and while different treatment modalities can complement one another, there is a need for continued development of new and better treatment options. Full article

This article offers a descriptive analysis of a specific form (uṣūl) of prophetic eulogy (ṣalawāt) as vocally performed within Sufi orders such as the Rifāʿiyya, Qādiriyya, and Jarrahiyya of today’s Türkiye. It combines a music–theoretical and music–sociological as well as ritual–theoretical perspective to examine how the structured performance of these chants functions both as a spiritual practice and as a means of social formation. Drawing on this dual perspective, the article analyses the underlying musical structures and elements of the ṣalawāt chant, such as melody, rhythm, harmony, modal frameworks, and dynamics. By examining how these formal aspects shape the aesthetic experience, emotional resonance, and theological significance of the eulogy, the study aims to highlight its performative and affective potential within Sufi devotional practice. Within the ritual framework of Sufi orders (ṭarīqa), this rhythmic and collective performance acts as a practice of tazkiya an-nafs (self-purification), cultivating attentiveness, moral refinement, and communal belonging through synchronized voice, breath, and bodily presence. The repeated invocation of the Prophet Muḥammad, venerated as the perfect human (al-insān al-kāmil), thus becomes a means of fostering inner transformation and spiritual proximity. In this way, ṣalawāt chanting mediates religious meaning not only through text but through embodied experience and performative devotion. Full article

This study investigated whether self-adaptor behaviours, defined as non-communicative bodily actions such as touching one’s face or clasping one’s hands, facilitate lexical retrieval. Sixty Japanese-speaking adults were assigned to one of three conditions: a self-adaptor condition (instructed to hold their cheeks), a suppression condition (hand movements inhibited), and a control condition in which participants were allowed to move their hands freely. Participants completed a lexical retrieval task designed to elicit tip-of-the-tongue (TOT) states, followed by a recall task. Responses were categorised as successful retrieval, retrieval failure, TOT success, or TOT failure. Results showed that the self-adaptor condition achieved significantly more correct responses than the suppression condition, indicating that self-adaptor behaviour supports lexical access during retrieval difficulty. However, self-adaptor behaviour did not enhance the resolution of TOT states or improve recall performance. Video-based analysis further revealed that gestures increased markedly during TOT states, while self-adaptor behaviours were more frequent overall. These findings suggest that self-adaptor behaviour contributes to general lexical retrieval processes but does not directly facilitate the resolution of TOT states. The distinction between the functions of spontaneous bodily movements is therefore essential. This study extends the understanding of how embodied behaviours interact with verbal processes and underscores the cognitive significance of non-communicative bodily actions in speech production. Full article

This article examines Daoist ritual and meditative practices, primarily developed between the fourth and twelft centuries, as cosmotechniques: methods for engaging, recalibrating, and occasionally overturning the spatial and temporal order. It first outlines the cosmological framework of the pre-Qin and Qin–Han periods, in which space and time were conceived as correlative and qualitative, forming the grounds of Daoist practice. Daoist foundational practices elaborately aligned with this framework but also introduced subtle disruptions that discover the singular space–time for transformation. Through the investigation of bodily cultivation and communal rituals, this study argues for attention to the performative aspect of Daoist practices, aiming to access and enact alternative space–time, and suggesting a dynamic interplay between alignment and disruption. The study further analyzes internal alchemy and visionary practices that engage in radical reversals of natural rhythms—employing fire, dissolution, and systemic negation to reconfigure cosmic flow. As shown here, Daoist practice is not merely contemplative but performative, reconstituting space–time and body. Though not articulated in ecological terms, such practices demonstrate ways of modeling and modulating lifeworlds attuned to the rhythms of nature—pointing to the possibility of reshaping life under unplugged conditions. Full article

Background/Objectives: End-of-life (EOL) HIV cure research, which studies HIV persistence through pre- and post-mortem tissue collection, has focused primarily on people living with HIV (PLWH) with a prognosis of six months or less. However, the perspectives of long-term survivors (LTS) diagnosed before the advent of effective antiretroviral treatment (ART) remain underexplored. Understanding their motivations and concerns about EOL cure research is essential for creating inclusive and ethical research frameworks. Methods: Between 2023 and 2024, we conducted in-depth qualitative interviews with 16 PLWH aged 60 and older from diverse backgrounds across the United States, recruited through community-based organizations and HIV networks. We used inductive thematic analysis to explore LTS’ perspectives on EOL HIV research. Results: Participants included cisgender men (56.25%) and women (43.75%) with diverse racial identities. While participants supported EOL HIV cure research, their willingness to participate varied, influenced by awareness, logistics, and ethical concerns. Altruism-motivated participation, but misconceptions about procedures and concerns over bodily integrity represented potential barriers. Some viewed blood draws and leukaphereses as routine, while others expressed hesitancy with biopsies and post-mortem tissue retrieval. HIV stigma, historical mistrust, and cultural beliefs also played a role in willingness to participate. LTS emphasized the need for decentralized research sites, travel support, and financial safeguards. Conclusions: To include LTS in EOL HIV cure research, a community-driven approach is needed, focusing on clear communication, ethical considerations, logistical support, and linkages to EOL care. Addressing misconceptions and building trust, particularly within groups traditionally underrepresented in research, is essential to expanding participation. Full article