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Search Results (180)

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16 pages, 297 KiB  
Article
How to Disappear Completely
by Dominik Zechner
Humanities 2025, 14(8), 161; https://doi.org/10.3390/h14080161 - 4 Aug 2025
Viewed by 247
Abstract
This article investigates the paradox of disappearance as both an aesthetic and a political phenomenon. Taking inspiration from Radiohead’s song “How to Disappear Completely,” it argues that aesthetic representations of disappearance never achieve total erasure; instead, they give rise to new forms of [...] Read more.
This article investigates the paradox of disappearance as both an aesthetic and a political phenomenon. Taking inspiration from Radiohead’s song “How to Disappear Completely,” it argues that aesthetic representations of disappearance never achieve total erasure; instead, they give rise to new forms of visibility. A true aesthetics of disappearance does not exist. Through case studies such as H.G. Wells’s The Invisible Man and Guy Debord’s Society of the Spectacle, the article demonstrates that disappearance is always mediated: the invisible man becomes hyper-visible through his clothing, bandages, and mask, while the spectacle conceals marginalized lives only to expose them through mechanisms of institutional control (e.g., prisons, medical facilities, schools—as analyzed in Michel Foucault’s work). An investigation of the “novel of the institution” (Campe), especially as it appears in the works of Franz Kafka and Robert Walser, eventually explores the nexus between aesthetic representation and institutionalized forms of coerced visibility. Ultimately, the essay argues that disappearance, as an aesthetic and political event, destabilizes regimes of visibility—not by erasure alone, but by exposing the fragility of appearance itself. The tension between opacity and exposure suggests that resistance lies not in pure absence but in subverting the very mechanisms of representation. Full article
(This article belongs to the Section Cultural Studies & Critical Theory in the Humanities)
12 pages, 239 KiB  
Article
Ten Years’ Experience Using Proxymetacaine Hydrochloride 0.5% for Postoperative Pain Control in Epithelium-Off Corneal Crosslinking
by Mohamed Gamal Elghobaier, Issac Levy and Mayank A. Nanavaty
J. Clin. Med. 2025, 14(13), 4692; https://doi.org/10.3390/jcm14134692 - 2 Jul 2025
Viewed by 275
Abstract
Background/Objectives: To evaluate the efficacy and safety of using the preservative-free topical proxymetacaine hydrochloride (Minims, 0.5% w/v, Bausch & Lomb, UK) to control postoperative pain after epithelium-off corneal crosslinking (CXL) for keratoconus. Methods: This is an observational study [...] Read more.
Background/Objectives: To evaluate the efficacy and safety of using the preservative-free topical proxymetacaine hydrochloride (Minims, 0.5% w/v, Bausch & Lomb, UK) to control postoperative pain after epithelium-off corneal crosslinking (CXL) for keratoconus. Methods: This is an observational study of patients with mild to severe keratoconus who have undergone epithelium-off CXL. CXL was completed by applying dextran-free riboflavin (0.1%) for 10 min (Vibex Rapid; Avedro, Inc.), followed by continuous UV-A light (Avedro KXL system; Avedro, Inc.) for 30 min at an intensity of 3 mW/cm2 and an energy of 5.4 J/cm2. All patients were prescribed postoperative proxymetacaine hydrochloride PRN with an allowed frequency of up to eight times per 24 h for the first 3 days to control postoperative pain. Patients were reviewed at 1–2 weeks postoperatively for a comprehensive examination, including assessment of delayed corneal healing, removal of the bandage contact lens, and recording of subjective symptoms. Results: There were 223 eyes of 180 patients with a mean age of 24.9 ± 8.6 years (range: 13–38 years). Male patients were 72%. At their planned first postoperative visit, we found no corneal healing abnormalities, such as persistent epithelial defects, epithelial irregularities, or early postoperative stromal haze, in any patient. All patients subjectively reported that proxymetacaine drops helped them to control postoperative pain, particularly in the first 48 h. Conclusions: None of the patients reported pain after 3 days of using proxymetacaine drops up to eight times a day for the first 3 days. It appears to be a safe and effective solution to control postoperative pain without any complications. Full article
(This article belongs to the Special Issue Advances in Anterior Segment Surgery: Second Edition)
13 pages, 729 KiB  
Systematic Review
Radial Hemostasis Devices and Post-Procedural Arterial Occlusion: Network Meta-Analysis of Randomized Controlled Trials
by Mauro Parozzi, Antonio Bonacaro, Mattia Bozzetti, Giovanni Cangelosi, Maria Bertuol, Fabio Mozzarelli, Paolo Ferrara, Stefano Mancin and Stefano Terzoni
J. Vasc. Dis. 2025, 4(3), 25; https://doi.org/10.3390/jvd4030025 - 25 Jun 2025
Viewed by 320
Abstract
Background/Objectives: Radial artery occlusion (RAO) following hemostasis after coronary procedures is the most common complication, with a highly variable incidence (1–33%). While it is well established that the patent hemostasis technique reduces RAO rates, it remains unclear which device should be preferred. The [...] Read more.
Background/Objectives: Radial artery occlusion (RAO) following hemostasis after coronary procedures is the most common complication, with a highly variable incidence (1–33%). While it is well established that the patent hemostasis technique reduces RAO rates, it remains unclear which device should be preferred. The wide variety of available radial hemostasis devices makes it necessary to identify those associated with a lower incidence of complications. Methods: Literature from 2016 to 2021 was reviewed through a systematic search in PubMed, CINAHL, Cochrane, and Embase databases. Only randomized controlled trials (RCTs) involving adult patients undergoing percutaneous transradial coronary procedures were included. Devices considered included pneumatic compression devices, manual compression, elastic bandages, and hemostatic dressings. The review process followed PRISMA guidelines. Two random-effects frequentist network meta-analyses were conducted to compare the effects of 16 and 9 radial hemostasis devices on RAO incidence at 24 h and 30 days after the procedure. Results: A total of 17 RCTs were included. The network meta-analysis (NMA) showed a protective effect at the 24 h endpoint for both double-balloon devices and pneumatic compression devices adjusted to mean arterial pressure. At the 30-day endpoint, significant differences were observed among pneumatic compression, chitosan-based PADs, mechanical compression devices, and adjustable elastic bandages. Conclusions: Although some treatments with specific devices significantly differ from the reference treatment, the limited availability of data to assess RAO at 30 days and a certain heterogeneity between devices indicate the need for further investigation. Full article
(This article belongs to the Section Cardiovascular Diseases)
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23 pages, 4665 KiB  
Article
Investigation of the Influence of Washing on the Physical and Mechanical Properties of Polymer Materials for Bandages
by Maja Somogyi Škoc, Slavica Bogović, Antonija Čulina and Iva Rezić Meštrović
Polymers 2025, 17(11), 1552; https://doi.org/10.3390/polym17111552 - 2 Jun 2025
Viewed by 628
Abstract
An elastic bandage or tensor bandage is widely known as a flexible medical device made of polymer materials. It is usually made of cotton and reinforced with elastic yarns. Depending on the therapy and clinical picture, elastic bandages are used for compression treatment [...] Read more.
An elastic bandage or tensor bandage is widely known as a flexible medical device made of polymer materials. It is usually made of cotton and reinforced with elastic yarns. Depending on the therapy and clinical picture, elastic bandages are used for compression treatment and as support bandages. The aim of this work was to carry out a washing process and investigate its influence on the physical–mechanical properties of elastic bandages. The washing process was carried out at 40 °C with 25, 50, 60, and 70 wash cycles using Autowash 311L. The elastic bandages were subjected to a tensile load. The tensile strength, elongation, elasticity, and structural properties of the elastic bandages were determined. The results of the elongation show that the values increase with the wash cycles (in standard soap) and decrease after 70 cycles (in standard soap without phosphate). The tensile strength values are highest after 25 wash cycles. The results of the cyclic elasticity measurements show that the elastic bandages do not lose their elongation properties after the first cycle. After the second to fifth cycle, the samples do not return to their original or almost original dimensions when the tensile load is stopped. In addition, an analysis of the data from the 3D leg scanning and an approximation of the compression of the bandages was performed. The circularity and compression values after 60 washes remain within the limits in which the compression bandage can fulfill the compression function. Full article
(This article belongs to the Special Issue Advanced Study on Polymer-Based Textiles)
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17 pages, 650 KiB  
Article
Offloading Strategies Used for Plantar Diabetic Foot Ulcers and Their Outcomes in Real-Life Clinical Practice
by Afram Rumanes, Jaap J. van Netten, Kor H. Hutting, Lisette J. E. W. C. van Gemert-Pijnen and Jeff G. van Baal
J. Clin. Med. 2025, 14(11), 3834; https://doi.org/10.3390/jcm14113834 - 29 May 2025
Viewed by 561
Abstract
Introduction: International guidelines describe offloading to facilitate healing as a cornerstone in the treatment of diabetes-related foot ulcers. In present-day clinics, various offloading devices are used. The aim of this paper is to describe the effectiveness in healing of different offloading devices used [...] Read more.
Introduction: International guidelines describe offloading to facilitate healing as a cornerstone in the treatment of diabetes-related foot ulcers. In present-day clinics, various offloading devices are used. The aim of this paper is to describe the effectiveness in healing of different offloading devices used in real-life clinical practice in patients with diabetes-related foot ulcers. Methods: A retrospective cohort study of 235 patients with a plantar foot ulcer in one diabetic foot centre of expertise was used. Clinical outcomes were determined during a follow-up period of 12 months. Groups were defined according to the types of offloading. Univariate and multivariate analysis was performed to assess ulcer-related outcomes in different offloading devices. Results: Of the 235 patients, 3% were treated with a Total Contact Cast (TCC), 9% with an ankle-high removable device, 32% with a custom-made orthopaedic shoe, 16% with a bandage shoe, and 39% with felted foam. Patients who received a bandage shoe or felted foam had a higher UT classification (Stage D in 21% and 18%, respectively, p = 0.001) and more ulcers per foot (13% and 5%, respectively, p = 0.002). The overall healing rate at 12 weeks was 33% and was not significantly different between the offloading device groups (p = 0.255). Healing rates at 20 and 52 weeks were 51.5% and 77%. Conclusions: Removable ankle-high offloading devices, orthopaedic shoes, bandage shoes, and felted foam are the most frequently used for plantar diabetic foot ulcers in clinical practice. This seems to be the result of various physician- and patient-related factors such as logistical reasons, patient factors, and severity of complicated ulcers. Diabetic foot ulcer healing after 12 weeks, 20 weeks, and 1-year follow-up were consistent with previous observational studies. Full article
(This article belongs to the Section Endocrinology & Metabolism)
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15 pages, 6682 KiB  
Article
Experimental Ancient Egyptian Human Mummification Tested in a Porcine Model: Excellent Preservation at a 13-Year Follow-Up
by Andreas G. Nerlich, Stephanie Panzer, Florian Fischer and Oliver K. Peschel
Heritage 2025, 8(6), 194; https://doi.org/10.3390/heritage8060194 - 28 May 2025
Viewed by 613
Abstract
Aim of the study: Several previous experimental studies simulated ancient Egyptian mummification of human bodies using the embalming protocol described by Herodotus. Besides two human experiments, several animal studies have been performed with very different species, mostly over short observation periods. We used [...] Read more.
Aim of the study: Several previous experimental studies simulated ancient Egyptian mummification of human bodies using the embalming protocol described by Herodotus. Besides two human experiments, several animal studies have been performed with very different species, mostly over short observation periods. We used a human-sized piglet model that matches closely to humans and undertook a long-term experiment with two detailed examination time points over 13 years. This was conducted to test the efficacy of the Herodotus embalming method in the long term. Material and Methods: An 88 kg piglet, 1.30 m body length, obtained from a veterinary practice was chosen as the skin is similar to humans. Using the described formula, the carcass was cleaned, eviscerated, filled with spices and natron sachets, and then covered with 240 kg of natron for 40 days. It was then reopened, and most of the sachets were removed. The surface was cleaned with wine, the body cavity partly refilled with sachets and spices, the surface treated with oils, wax, honey and bitumen, and finally sealed with linen bandages. The body weight was regularly monitored over the 13-year period. At 7 and 13 years, re-examination, with a protocol including CT scanning, histology and microbiology, was performed. Results: The monitoring of the body weight showed a rapid loss of weight within the first year, gradually slowing, reaching more than 66% of its weight. In the final 6 years, the body weight was reduced by only 1.7 kg. The CT scans at 7 years and 13 years showed that the structures of the heart, muscle, skin, and soft tissue were well preserved, and the body significantly shrunken; only the musculature showed air inclusions. Histology and microbiology (examined at baseline, 7 years and 13 years) revealed excellently conserved tissue with anaerobic microbe spores, very limited tissue destruction, and no significant fungal or parasitic invasion. However, the preserved kidneys and internal genitalia had disappeared. Conclusions: This ongoing long-term project confirmed excellent mummification with near-perfect body conservation at 13 years, supporting the efficacy of the described Herodotus technique. This model is suitable for the assessment of special preservation techniques recently suggested for individual soft tissue organs. Full article
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22 pages, 4476 KiB  
Article
A Bioelectrically Enabled Smart Bandage for Accelerated Wound Healing and Predictive Monitoring
by Ahmad F. Turki and Aziza R. Alrafiah
Medicina 2025, 61(6), 965; https://doi.org/10.3390/medicina61060965 - 23 May 2025
Cited by 1 | Viewed by 1420
Abstract
Background and Objectives: Chronic wounds pose a significant healthcare burden due to their prolonged healing times and susceptibility to infection. Electric field (EF)-enabled smart bandages offer a promising solution by combining therapeutic stimulation with real-time physiological monitoring. Materials and Methods: This study assessed [...] Read more.
Background and Objectives: Chronic wounds pose a significant healthcare burden due to their prolonged healing times and susceptibility to infection. Electric field (EF)-enabled smart bandages offer a promising solution by combining therapeutic stimulation with real-time physiological monitoring. Materials and Methods: This study assessed a smart bandage integrating spiral stainless steel electrodes delivering a 200 millivolts per millimeter (mV/mm) EF for 5 h daily over 14 days to full-thickness excisional wounds in 100 Sprague–Dawley rats. Vital signs including heart rate (BPM), oxygen saturation (SpO2), and temperature were monitored continuously. Machine learning models were trained on these data to predict wound healing status. Results: By Day 7, EF-treated wounds demonstrated significantly faster healing, achieving an average wound closure rate of 82.0% ± 2.1% compared to 70.75% ± 2.3% in the control group (p < 0.05). By Day 14, wounds in the experimental group had significantly reduced to 0.01 ± 0.005 cm2, while the control group retained a wound size of 0.24 ± 0.03 cm2 (p < 0.05). Histological analysis revealed enhanced neovascularization, collagen alignment, and epithelial regeneration in the EF group. Physiological data showed no systemic inflammatory response. Predictive modeling using XGBoost and Random Forest achieved >98% accuracy, with SHAP (SHapley Additive exPlanations) analysis identifying EF exposure and treatment duration as key predictors. Conclusions: The findings demonstrate that EF-based smart bandages significantly enhance wound healing and enable highly accurate prediction of outcomes through machine learning models. This bioelectronic approach holds strong potential for clinical translation. Full article
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24 pages, 3234 KiB  
Article
Uncovering the Advantages of Foam Dressings with Active Ingredients
by Daniela Chrysostomou, Georgios E. Papanikolaou, Lorraine Boshoff, Thandazi Mbele, Andrea Pokorná, Adéla Holubová, Frank A. D. T. G. Wagener and Niels A. J. Cremers
Pharmaceuticals 2025, 18(6), 768; https://doi.org/10.3390/ph18060768 - 22 May 2025
Viewed by 1273
Abstract
Background/Objectives: Foam dressings are designed for their ability to manage exudate and are selected to optimize wound repair. Various foam dressings are available, ranging from basic polyurethane to more sophisticated options, incorporating active components to combat infections or foster healing. This study investigates [...] Read more.
Background/Objectives: Foam dressings are designed for their ability to manage exudate and are selected to optimize wound repair. Various foam dressings are available, ranging from basic polyurethane to more sophisticated options, incorporating active components to combat infections or foster healing. This study investigates the requirements for the most suitable foam dressing through a combination of field research, laboratory testing, and clinical evaluation. Methods: We tested 17 foam dressings commonly used by wound care professionals while attending an international conference. An effective foam dressing should absorb wound fluid for several days, as wound care professionals value absorption and retention capacity, often favoring less frequent changing dressings, preferably twice a week or even weekly. Results: The foam dressings tested can absorb the expected amount of exudate typically produced by different wound types. There is some variability in retention capacity and product prices, resulting in differences in cost-effectiveness among products. In addition, some dressings are enriched with active ingredients that can accelerate healing through their antimicrobial and anti-inflammatory properties, such as foam dressings infused with silver or honey. A honey-based foam dressing was evaluated in a clinical survey involving eight wound care specialists, and four clinical cases with varying wound pathologies were discussed in more detail to highlight its key properties. Conclusions: Ideally, a foam dressing should have adequate absorption and retention capacities, effectively resolve and prevent infections, protect against external trauma, ensure optimal patient comfort without damaging newly formed granulation tissue, accelerate wound healing processes, and reduce wound care time (e.g., remaining in place for 7 days). Together, these factors make honey- or silver-loaded foam dressings more cost-effective than plain dressings due to their antimicrobial activities and ability to nourish tissues. Full article
(This article belongs to the Special Issue Applications of Beehive Products for Wound Repair and Skin Care)
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10 pages, 1243 KiB  
Article
Clinical Outcomes of Non-Elastic Compression Bandage Versus Elastic Bandage Following Lateral Ankle Ligament Repair
by Jie Yang, Guocheng Ding, Zhixin Duan, Yixiang Yan, Yuyue Zhang, Dong Jiang and Jianquan Wang
Healthcare 2025, 13(10), 1182; https://doi.org/10.3390/healthcare13101182 - 19 May 2025
Viewed by 635
Abstract
Objectives: This study aims to compare the postoperative clinical outcomes of using non-elastic compression bandages versus elastic bandages after lateral ankle ligament repair. Methods: This retrospective study analyzed a total of 110 patients who underwent repair surgery for chronic lateral ankle [...] Read more.
Objectives: This study aims to compare the postoperative clinical outcomes of using non-elastic compression bandages versus elastic bandages after lateral ankle ligament repair. Methods: This retrospective study analyzed a total of 110 patients who underwent repair surgery for chronic lateral ankle ligament injuries. Based on the postoperative bandaging method, patients were divided into two groups: the non-elastic compression bandage group (Group NECB, 55 cases) and the elastic bandage group (Group EB, 55 cases). A comparison was made between the two groups of patients regarding postoperative ankle joint swelling, pain scores (VAS scores), ankle function (AOFAS Ankle–Hindfoot Scale), range of motion of the ankle joint, the incidence of perioperative complications (including subcutaneous ecchymosis, wound seepage, and events requiring loosening of the bandage due to pain), and the status of return to work postoperatively. Results: There were no significant differences between the two groups in terms of early postoperative ankle joint swelling or increased circumference (0.53 ± 1.47 cm vs. 1.08 ± 1.84 cm, p = 0.095) or VAS scores at 1 day (3.84 ± 2.14 vs. 3.63 ± 2.03, p = 0.595), 7 days (2.20 ± 1.89 vs. 1.78 ± 1.67, p = 0.216), 14 days (1.45 ± 1.56 vs. 0.97 ± 1.23, p = 0.075), or 3 months (1.27 ± 1.50 vs. 1.38 ± 1.76, p = 0.744). Both groups demonstrated comparable functional recovery based on AOFAS scores at 3 months (89.89 ± 8.08 vs. 90.05 ± 9.50, p = 0.926), ROM in all measured directions (p > 0.05), and return to work status (p = 0.567). However, the incidence of complications was significantly lower in Group NECB (3.6%) compared to Group EB (30.9%). The reported complications in Group EB were mainly related to postoperative subcutaneous ecchymosis and discomfort requiring bandage loosening. Conclusions: There is no difference between non-elastic compression bandaging with cotton padding and elastic bandaging in postoperative swelling, pain, and functional recovery. However, in reducing the incidence of postoperative skin adverse events, using non-elastic compression bandages with cotton padding proves to be more ideal as a bandaging method after lateral ankle ligament repair. Full article
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23 pages, 4982 KiB  
Article
Laser-Ablative Structuring of Elastic Bandages—An Experimental Study
by Peijiao Huang, Daoyong Zhang, Wenyuan Lu, Xihuai Wang, Da Chen, Shengbin Zhao and Mingdi Wang
Nanomaterials 2025, 15(9), 701; https://doi.org/10.3390/nano15090701 - 7 May 2025
Viewed by 435
Abstract
To address the problem of excessive ablation in conventional laser processing caused by the inhomogeneous energy distribution at the focal point, along with the inherent heterogeneity and surface irregularities of textile materials, a new method for laser printing elastic bandage fabrics was developed. [...] Read more.
To address the problem of excessive ablation in conventional laser processing caused by the inhomogeneous energy distribution at the focal point, along with the inherent heterogeneity and surface irregularities of textile materials, a new method for laser printing elastic bandage fabrics was developed. We used flat top light sources, short focal field mirrors, and low power lasers instead of the Gaussian light sources, long focal field mirrors, and high-power lasers used in traditional methods. First, the sample was preheated, and the aspherical lens system was designed and simulated. Then, the physical and chemical properties of laser-processed elastic bandage fabrics were investigated. Finally, based on single-factor experiments, orthogonal experimental analysis was conducted to determine the optimal process parameters. The results show that the optimized optical path can effectively improve the uniformity of the temperature field during laser scanning and enhance focusing performance; as energy gradually accumulates, chemical bonds in polymer molecules break; when the elastic bandage fabric is in a highly elastic state, it exhibits appropriate breaking strength and color difference. The best parameters obtained from the single-factor experiment are as follows: laser power range of 25–34 W, scanning speed range of 2200–2800 mm/s, preheating temperature range of 125–200 °C. The best parameters obtained from the orthogonal experiment are as follows: laser power 28 W, scanning speed 2800 mm/s, and the preheating temperature 175 °C. Full article
(This article belongs to the Section Nanofabrication and Nanomanufacturing)
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13 pages, 763 KiB  
Article
Physiotherapy Intervention in the Immediate Postoperative Phase of Lipedema Surgery—Observational Study
by Ángela Río-González, Esther Delgado-Pérez, Elisa García-García, Laura González-Fernández, Sara García-Isidoro and Ester Cerezo-Téllez
J. Clin. Med. 2025, 14(7), 2137; https://doi.org/10.3390/jcm14072137 - 21 Mar 2025
Viewed by 2141
Abstract
Background: Lipedema is an adipose tissue disorder in women, with an abnormal fat deposition in lower limbs and occasionally upper limbs. The condition is characterized by pain, bruising, heaviness, and mobility impairment. Objectives: This study aims to evaluate the effects of [...] Read more.
Background: Lipedema is an adipose tissue disorder in women, with an abnormal fat deposition in lower limbs and occasionally upper limbs. The condition is characterized by pain, bruising, heaviness, and mobility impairment. Objectives: This study aims to evaluate the effects of a modified Complete Decongestive Therapy protocol using the Godoy Method in the postoperative period following lipedema surgery. Methods: In total, 293 participants who underwent liposuction for lipedema were studied. The postoperative physiotherapy protocol included Godoy cervical stimuli, Manual Lymphatic Drainage based on Godoy maneuvers, mechanical lymphatic drainage with RAGodoy®, compression with bandages, skin care, and therapeutic education. Results: This study found that the number of physiotherapy sessions significantly reduced pain (p = 0.000) and other complications (p = 0.007) and increased mobility (p = 0.003). The number of physiotherapy sessions showed significant differences in pain intensity at 90 days post-treatment (p = 0.000). In total, 47.24% of the participants became functionally independent on the third day of the physiotherapy intervention (p = 0.003). A total of 40.96% of the participants developed some complications, although a relationship between inadequate compression and the occurrence of complications was also found in 36.52% of patients. Conclusions: The success of surgical treatment for lipedema not only depends on the surgery itself but also on the proper management of the patient in the perioperative period to minimize complications and prevent recurrence. The Complete Decongestive Therapy protocol modified with the Godoy Method showed effects on pain reduction, mobility increase, edema reabsorption, and prevention of complications, consequently enhancing functionality and quality of life for patients undergoing lipedema surgery. Full article
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31 pages, 7303 KiB  
Article
Dynamics of Steel Gas Pipelines: Finite Element Simulation of Damaged Sections Reinforced with Composite Linings
by Arman Moldagaliyev, Nurlan Zhangabay, Marco Bonopera, Raimberdi Ristavletov, Ulzhan Ibraimova and Shairbek Yeshimbetov
Vibration 2025, 8(1), 8; https://doi.org/10.3390/vibration8010008 - 27 Feb 2025
Cited by 1 | Viewed by 676
Abstract
Based on a reduced model of a linear section of a steel gas pipeline between four supports and with a crack-like through defect, ANSYS FE software is used in this study to develop numerical approaches regarding three key parameters of a composite bandage [...] Read more.
Based on a reduced model of a linear section of a steel gas pipeline between four supports and with a crack-like through defect, ANSYS FE software is used in this study to develop numerical approaches regarding three key parameters of a composite bandage in the form of a circular lining: the type of composite material and the length and thickness of the composite lining. The approach for assessing the static strength of a damaged section of a steel pipeline with a composite lining that is subjected to internal pressure allows for the determination of the optimal thickness of the composite lining itself, which is equal to the indicator “50.0% to 62.5%” of the pipe thickness. Furthermore, the approach for assessing the dynamic strength and analyzing the possible destruction of the reinforced damaged section of a pipeline experiencing an increase in internal pressure allows for the determination of the optimal length of the composite lining, which, in turn, should be at least 241.2 mm. This work also considers cases when there is no internal pressure and the steel pipeline is subjected to critical pressure. It is found that the frequency spectrum of pipeline oscillations without a composite lining is higher than that with a composite lining. The difference between the corresponding dynamic oscillations increases with the thickness or the length of the composite lining. In the absence of internal pressure, all frequencies of the steel pipeline with a crack closed by a composite lining are paired. This pairing is disrupted when the pipeline is subjected to critical internal pressure, and the difference between its oscillation frequency spectrum without and with a composite lining increases. In this case, the oscillation modes significantly differ from those of the same pipeline structure when unloaded. The results ensure the optimal stress distribution in the defect area of a steel pipeline wall and improve the reliability and safety of pipelines under seismic actions. The approach for increasing dynamic strength and eliminating defects can be applied to pipelines with a large diameter regardless of the causes and geometric dimensions of the defects. Moreover, this approach to increasing the strength can be used by various industries and/or institutes which work on the design of new, earthquake-resistant, reinforced pipelines. Full article
(This article belongs to the Special Issue Nonlinear Vibration of Mechanical Systems)
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25 pages, 376 KiB  
Review
Predictors of the Efficacy of Lymphedema Decongestive Therapy
by Andrej Dzupina, Nagendra Yaluri, Jaipaul Singh and Monika Jankajova
Medicina 2025, 61(2), 231; https://doi.org/10.3390/medicina61020231 - 27 Jan 2025
Viewed by 3637
Abstract
Lymphedema is a chronic condition characterized by the accumulation of lymphatic fluid in the tissues, causing swelling primarily in the limbs, though other body parts can also be affected. It commonly develops after lymph node removal, or radiation therapy, or due to congenital [...] Read more.
Lymphedema is a chronic condition characterized by the accumulation of lymphatic fluid in the tissues, causing swelling primarily in the limbs, though other body parts can also be affected. It commonly develops after lymph node removal, or radiation therapy, or due to congenital lymphatic system defects. Effective management is essential due to its significant impact on physical function and quality of life. Complete Decongestive Therapy (CDT) is the primary treatment for lymphedema. This comprehensive approach combines manual lymphatic drainage (MLD), compression bandaging, skincare, and exercise. An early diagnosis and initiation of CDT are critical to preventing irreversible damage to the lymphatic system and worsening symptoms. Successful outcomes depend on timely treatment, patient adherence, and the consistent use of all CDT components, with compression therapy and exercise playing particularly vital roles. Recent research highlights how skin and fat tissue characteristics, such as increased skin thickness and adipose tissue accumulation, complicate lymphedema management, especially in advanced stages. In these cases, where fibrosis and fat deposition are more prominent, traditional CDT may need to be supplemented with advanced treatments like liposuction or enhanced compression techniques. This study explores the factors influencing the success of decongestive therapy, including the stage of lymphedema at the diagnosis, treatment protocols, and individual patient characteristics like skin and fat tissue properties. Full article
(This article belongs to the Section Dermatology)
14 pages, 916 KiB  
Article
Topical Application of Manuka Honey for the Treatment of Non-Healing Venous Leg Ulcers
by Marek Kucharzewski, Kinga Spyrka, Ewa Rojczyk and Jakub Brela
Pharmaceuticals 2025, 18(2), 149; https://doi.org/10.3390/ph18020149 - 23 Jan 2025
Cited by 3 | Viewed by 2863
Abstract
Background/Objectives: Issues related to the chronic venous leg ulcer (VLU) treatment and prevention of recurrences remain the subject of research, but so too do common clinical problems in daily medical practice. Due to its medicinal properties, Manuka honey is increasingly used in [...] Read more.
Background/Objectives: Issues related to the chronic venous leg ulcer (VLU) treatment and prevention of recurrences remain the subject of research, but so too do common clinical problems in daily medical practice. Due to its medicinal properties, Manuka honey is increasingly used in the treatment of wounds of various origins. The aim of the study was to investigate the effectiveness of Manuka honey for the topical treatment of non-healing, chronic, venous leg ulcers. Methods: Eighty patients with chronic VLU participated in the study and were randomized into two equinumerous groups. In group 1, patients were treated with topical Manuka honey application and short stretch bandage compression, whereas, in group 2, antimicrobial calcium alginate wound dressing + Ag was used instead of Manuka honey. The efficacy of both treatment methods was compared. Results: The ulcerations in patients from group 1 have healed completely after up to seven weeks of therapy in all cases. In contrast, in all patients from group 2, the healing process was longer but completed successfully after up to 14 weeks of the therapy. The process of wound cleaning from microorganisms was also faster in group 1, as well as the reduction in ulcer area during treatment. Conclusions: It was found that the topical administration of Manuka honey may be a promising alternative to traditional methods of non-healing VLU treatment. Full article
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7 pages, 1757 KiB  
Case Report
Combined Multilayered Amniotic Membrane Graft and Fibrin Glue as a Surgical Management of Limbal Dermoid Cyst
by Maria Poddi, Vito Romano, Alfredo Borgia, Floriana Porcaro, Carlo Cagini and Marco Messina
J. Clin. Med. 2025, 14(2), 607; https://doi.org/10.3390/jcm14020607 - 18 Jan 2025
Cited by 1 | Viewed by 906
Abstract
Background/Objectives: To report the cosmetic, clinical, and visual outcomes of a combined surgical approach for treating a corneal/limbal dermoid using excision and a three-layered amniotic membrane graft with fibrin glue. Methods: An 18-year-old female presented with impaired vision and ocular discomfort caused by [...] Read more.
Background/Objectives: To report the cosmetic, clinical, and visual outcomes of a combined surgical approach for treating a corneal/limbal dermoid using excision and a three-layered amniotic membrane graft with fibrin glue. Methods: An 18-year-old female presented with impaired vision and ocular discomfort caused by a prominent dome-shaped limbal congenital dermoid on the inferotemporal cornea, resulting in a significant aesthetic concern. A full assessment, including refraction, best-corrected visual acuity (BCVA), corneal topography, aberrometry and anterior segment OCT (AS-OCT) was conducted to plan the surgical approach. The dermoid was excised under peribulbar anaesthesia using manual lamellar dissection, followed by the application of 0.02% Mitomycin C and a multilayered amniotic membrane graft with fibrin glue. A bandage contact lens was applied and removed after three weeks, with postoperative treatment including topical antibiotics and steroids. Follow-ups were conducted on day 1, at 1 week, 3 weeks, 2 months, 6 months, 1 year, and 2 years. Results: Histopathological examination confirmed the mesoblastic nature of the lesion. Significant improvements in BCVA and ocular symptoms were observed. Corneal topography showed ocular surface regularization with reduction of high order aberrations and point spread function. AS-OCT showed complete integration of the amniotic membrane, with full epithelial coverage of the defect. The healing process was uneventful and the ocular surface remained stable throughout the entire follow-up, without complications or recurrence. Conclusions: This approach of dermoid excision, multilayered amniotic membrane and fibrin glue restored vision effectively, with notable improvements in ocular surface and cosmetic outcomes, without recurrence over two years. Full article
(This article belongs to the Special Issue Keratitis and Keratopathy: New Insights into Diagnosis and Treatment)
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