Search Results (416)

Microplastic (MP) pollution poses an emerging environmental concern, yet current methods for isolation and quantification are often time-consuming, costly, and poorly adapted to real-world variability. In this study, a workflow for the preparation, filtration, and quantification of MP standards, emphasizing environmental relevance and methodological efficiency, was developed and evaluated. To address the scarcity of irregularly shaped MP standards, low-cost, environmentally representative standards were lab-prepared by grinding and sieving plastic sheets. These MPs were successfully categorized according to sizes up to ~250 μm and dyed for enhanced visibility. The filtration efficiency for two systems, a long-circuit pump (LC-pump) and a short-circuit vacuum (SC-vacuum), was compared. The SC-vacuum method demonstrated a more than 11-fold increase in filtration speed and higher MP recovery rates for both polystyrene and polypropylene standards. Ethanol-based solvents significantly improved MP dispersion and recovery for irregular shapes of the MPs, including polystyrene and polypropylene. Finally, a user-guided machine learning tool (Ilastik) was implemented for automated MP quantification. Ilastik showed a strong correlation with manual counting (r = 0.824) and reduced variability, offering a reproducible and time-efficient alternative. By cutting down cost, time, and technical complexity relative to existing MP analysis techniques, this workflow provides a more accessible path toward consistent and scalable environmental MP assessments. Full article

In recent years, the need for autonomous underwater vehicles (AUVs) for offshore infrastructure maintenance and oceanographic surveillance has been prominently increasing. Continuous monitoring and surveillance are the essential tasks the AUVs are designed to perform. However, the long endurance of the AUV is a challenging task due to the limited size and capacity of the onboard battery. The conventional way of recharging using battery swapping or a wet mate connector limits the autonomy of the AUV. Underwater wireless power transfer (UWPT) technology seems to be a suitable alternative for overcoming the above limitations, which can provide autonomy to the AUV charging process. However, designing a UWPT system has its limitations in the marine environment and requires enough engineering studies of the different modules of the system. Different investigations are proposed in the literature on the UWPT system, both at the system level and circuit level. This article provides an overview of the latest advancements in the UWPT system and discusses marine power sources, power converter topologies, compensation topologies, and different types of magnetic couplers. The article also discusses the engineering challenges in designing a UWPT system, including eddy current loss and biofouling. The article also summarizes current research trends, potential challenges in UWPT, and future technological developments from prototypes to practical products and offers recommendations for further progress. Full article

Magnetron-sputtered coatings consisting of multiple alternating layers of chromium and amorphous carbon (Cr/a-C)ml were deposited on HS6-5-2 steel with an intermediate chromium layer by varying deposition rates. Three series of coatings, S1, S2, and S3, with thicknesses of 1.74, 1.15, and 1.14 μm and average chromium contents of 89.3, 66.0, and 59.7 wt.% Cr, respectively, were obtained. Open-circuit potential, cyclic potentiodynamic measurements, and electrochemical impedance spectroscopy were used to characterize their corrosion resistance in 3.5% NaCl. The surfaces were observed with optical and scanning electron microscopy before and after the corrosion tests, and changes in the elemental composition were monitored by energy-dispersive spectroscopy. The protective properties of coatings from series S2 and S3 are similar and significantly better than those of S1. They are characterized by a corrosion current below 1 μA cm^–2 and a stable passive state up to over 0.9 V_Ag/AgCl. The coatings have cathodic behavior towards the substrate, and when the coatings are damaged, galvanic corrosion causes deep pits. Coatings deposited at lower rates and with higher carbon content demonstrate significantly enhanced corrosion resistance in 3.5% NaCl. All three series of Cr/(Cr/a-C)ml@HS6-5-2 exhibit identical corrosion behavior after compromising the coatings’ integrity. Full article

For decades, researchers have explored the therapeutic potential of the vagus nerve through vagus nerve stimulation (VNS). Initially developed for epilepsy, VNS has since been applied to treat resistant depression, stroke recovery, and inflammatory conditions. Transcutaneous VNS (tVNS) now offers a noninvasive alternative, fueling clinical trials in disorders ranging from rheumatoid arthritis and migraines to long COVID-19. Mechanistic studies suggest that afferent and efferent vagal fibers modulate immune responses, mood regulation, and neurotransmitter systems. The SPARC initiative has accelerated mapping of vagal circuits, enabling more precise approaches to stimulation. Despite progress, the results remain mixed: while some patients experience lasting symptom relief, others respond no better than to placebo. Depression studies, in particular, highlight both the promise and the complexity of VNS, as inflammation, motivation circuits, and gut–brain signaling emerge as key modulators. Next-generation closed-loop devices and circuit-specific targeting may improve efficacy and reduce adverse effects. VNS research thus lies at the intersection of neuromodulation, psychiatry, and immunology—offering hope for hard-to-treat conditions, yet demanding rigorous trials to separate myths from medicine. In this article, we review the current clinical and experimental applications of tVNS, analyze its mixed efficacy across psychiatric, immunological, and neurological disorders, and highlight the mechanistic insights, stimulation parameters, and emerging technologies that may shape next-generation therapies. Full article

Currently, in influenza vaccine production via the chicken embryo splitting method, embryo viability detection is a pivotal quality control step—non-viable embryos are prone to microbial contamination, directly endangering the vaccine batch quality. However, the predominant manual candling method suffers from unstable accuracy and occupational visual health risks. To address this challenge, we developed a novel real-time embryo viability detection system based on photoplethysmography (PPG) technology, comprising a hardware circuit for chicken embryo PPG signal collection and customized software for real-time signal filtering and time–frequency-domain analysis. Based on this system, we conducted three pivotal experiments: (1) impact of the source–detector spatial arrangement on PPG signal acquisition, (2) viable/non-viable embryo discrimination, and (3) embryo PPG signal detection performance for days 10–14. The experimental results show that within the sample size (15 viable, 5 non-viable embryos), the system achieved a 100% discrimination accuracy; meanwhile, it realized 100% successful multi-day (days 10–14) PPG signal capture for the 15 viable embryos, with consistent performance across the developmental stages. This PPG-based system overcomes limitations of traditional and existing automated methods, provides a non-invasive alternative for embryo viability detection, and presents significant implications for standardizing vaccine production quality control and advancing optical biosensing for biological viability detection. Full article

Low-frequency alternating-current (LFAC) transmission has attracted significant attention for medium- and long-distance offshore wind integration due to its ability to mitigate the substantial charging currents and reactive power burdens associated with long submarine cables. This paper investigates the frequency-dependent electrothermal behaviors of a 500 kV three-core XLPE submarine cable using a coupled electromagnetic–thermal finite-element model. The simulation framework evaluates the current distribution, power losses in metallic components, temperature rise, and ampacity across various frequency regimes. To validate the numerical model, a thermal-circuit approach based on the IEC 60287 standard is developed, with comparisons confirming that deviations remain within acceptable engineering margins. The study reveals that operating at lower frequencies effectively mitigates skin and proximity effects, leading to reduced conductor and sheath losses. Quantitative results demonstrate that reducing the operating frequency from 50 Hz to 5 Hz results in a 30.6% reduction in total power losses and a 14.2% increase in current-carrying capability. These findings confirm that LFAC transmission offers a viable pathway to enhance the efficiency and capacity of submarine power transmission systems. Full article

The 2025 International Technology Roadmap for Photovoltaics (ITRPV) projects that bifacial modules will dominate the photovoltaic (PV) market, reaching roughly 60–80% global share between 2024 and 2035, while monofacial PV modules will steadily decline. Current industry practice is to route the cable bundles along structural members such as main beams or torque tubes, thereby preventing rear-side shading but resulting in two key drawbacks: increased cable length and decreased system reliability due to cable proximity with rotating members and pinch points. Both effects contribute to higher system costs and reduced cable reliability. An alternative method involves suspending cable bundles directly behind the modules using hangers. While this approach mitigates excess length and risk of cable snags, it introduces the possibility of partial rear-side shading, which could possibly cause performance loss and hot-spot formation due to shade-induced electrical mismatch. Experimental evidence indicates that this risk is minimal, as albedo irradiance typically represents only 10–30% of front-side irradiance as reported in the literature and is largely diffuse, thereby limiting the likelihood of significant directional shading. This study evaluates the performance and reliability impacts of hanger-supported cable bundles under varying experimental conditions. Performance metrics assessed include maximum power output (Pmax), short-circuit current (Isc), open-circuit voltage (Voc), and fill factor (FF), while hot-spot risk was evaluated through measurements of module temperature uniformity using infrared imaging. Each cable (1X) was 6 AWG with a total outer diameter of approximately 9 mm. Experiments covered different cable bundle counts/sizes (2X, 6X, 16X), mounting configurations (fixed-tilt and single-axis tracker), and albedo conditions (snow-covered and snow-free ground). Measurements were conducted hourly on clear days between 8:00 and 16:00 from June to September 2025. The results consistently show that hanger-supported cable bundles have a negligible shading impact across all hours of the day and throughout the measurement period. This indicates that rear-side cable shading can be safely and practically disregarded in performance modeling and energy-yield assessments for the tested configurations, including fixed-tilt systems and single-axis trackers with or without torque tube shading and with various hanger sizes and cable-bundle counts. Therefore, hanging cables behind modules is a cost- and reliability-friendly, safe and recommended practice. Full article

With the irregular integration of small-capacity distributed generators (DG) and single-phase loads, rural low-voltage distribution transformers are faced with issues such as three-phase imbalance, light-heavy loading, and feeder terminal voltage excursions, impacting the safe and stable operation of the system. To address this issue, a coordinated control strategy based on direct power control (DPC) for low-voltage substation series-parallel coordination is proposed. A flexible interconnection topology for multi-substation series-parallel coordination is designed to achieve coordinated optimization of alternating current–direct current (AC-DC) power quality. Addressing the three-phase imbalance, light-heavy loading, and feeder terminal voltage excursions in rural low-voltage distribution transformers, a series-parallel coordinated optimization control strategy is proposed. This strategy incorporates a DC bus voltage control strategy based on sequence-separated power compensation and a closed-loop control strategy based on phase-separated power compensation, effectively addressing three-phase imbalances and load balancing in each power distribution areas. Furthermore, a series-connected phase compensation control strategy based on DPC is proposed, efficiently mitigating feeder terminal voltage excursions. A corresponding circuit model is established using Matlab/Simulink, and simulation results validate the effectiveness of the proposed strategy. Full article

Large-scale wireless sensor networks with electric field energy harvesters (EFEHs) offer self-powered, eco-friendly, and scalable crop monitoring in hydroponic greenhouses. However, their practical adoption is limited by the low power density of current EFEHs, which restricts the reliable operation of external sensors. To address this challenge, this work presents a noninvasive EFEH assembled with hydroponic leafy vegetables that harvests electric field energy and estimates plant functional traits directly from the electrical response. The device operates through electrostatic induction produced by an external alternating electric field, which induces surface charge redistribution on the leaf. These charges are conducted through an external load, generating an AC voltage whose amplitude depends on the dielectric properties of the leaf. A low-voltage prototype was designed, built, and evaluated under controlled electric field conditions. Two representative species, Beta vulgaris (chard) and Lactuca sativa (lettuce), were electrically characterized by measuring the open-circuit voltage (VOC) and short-circuit current (ISC) of EFEHs. Three regression models were developed to determine the relationship between foliar moisture content (FMC) and fresh mass with electrical parameters. Empirical results disclose that the plant functional traits are critical predictors of the electrical output of EFEHs, achieving coefficients of determination of $R^2=0.697$ and $R^2=0.794$ for each species, respectively. These findings demonstrate that EFEHs can serve as self-powered, noninvasive indicators of plant physiological state in living leafy vegetable crops. Full article

Alzheimer’s disease and Parkinson’s disease remain the most prevalent neurodegenerative disorders associated with aging and continue to lack curative treatments. Their pathophysiology is often multifaceted, encompassing protein aggregation, mitochondrial dysfunction, chronic neuroinflammation, synaptic degeneration, and vascular compromise. This complex landscape reduces the effectiveness of single-target pharmacological agents and underscores the need for therapies capable of acting across multiple axes. Orthobiologics and peptide-based strategies exemplify this approach. Autologous cellular alternatives such as platelet-rich plasma, bone marrow aspirates, mesenchymal stromal cell derivatives, and extracellular vesicles deliver paracrine signals that can reprogram glia, preserve mitochondrial function, and promote synaptic and vascular repair. Peptide therapeutics, including glucagon-like peptide-1 receptor agonists and novel sequences targeting protein aggregation or mitochondrial pathways, provide complementary precision by engaging defined receptors and intracellular cascades. Together, these modalities converge on mechanisms central to circuit preservation rather than symptomatic relief alone. Preclinical studies across Alzheimer’s and Parkinson’s disease demonstrate consistent neuroprotective and functional benefits, and early human trials support feasibility and safety. The translational path forward requires standardized preparation, biomarker integration, optimized delivery routes such as intranasal administration, and regulatory frameworks adapted to biologic therapies. This review synthesizes current evidence on orthobiologics and peptides in neurodegeneration, outlines safety and translational considerations, and highlights future directions, including rational combinations and biomarker-driven trials. By uniting the broad signaling capacity of orthobiologics with the precision of peptides, neurology can move beyond symptomatic care toward regenerative strategies that aim to preserve neural circuits and improve long-term outcomes in Alzheimer’s disease and Parkinson’s disease. Full article

Nanoimprint lithography (NIL) is a high-resolution parallel patterning method based on molding. It has proven resolution down to the nanometer range and can be scaled up for large areas and high throughput. Its main characteristic is that the surface pattern of a mold is imprinted on a material that is displaced locally by using the difference in hardness of the mold and the moldable material, thus replicating its surface topography. This can be achieved by shaping a thermoplastic film by heating and cooling (T-NIL) or a photosensitive resin followed by a curing process for hardening (UV-NIL). In lithography, the local thickness contrast of the thin molded film can be used as a masking layer to transfer the pattern onto the underlying substrate. Therefore, NIL will be an alternative in fields in which electron-beam lithography and photolithography do not provide sufficient resolution at reasonable throughput. Direct imprint enables applications where a modified functional surface is needed without pattern transfer. NIL is currently used for high-volume manufacturing in different applications, like patterned sapphire substrates, wire grid polarizers, photonic devices, lightguides for AR/VR devices, metalenses, and biosensors for DNA analysis, and is being tested for semiconductor integrated circuit chips. Full article

The General AntiParticle Spectrometer is a balloon-borne experiment designed to search for low-energy cosmic-ray antinuclei as a potential indirect signature of dark matter. Over the course of at least three long-duration flights over Antarctica, it will explore the sub-$250 \mathrm{M}\mathrm{e}\mathrm{V}/\mathit{n}$ energy range with sensitivity to antideuterons and antihelium, while also extending antiproton measurements below 100 $\mathrm{M}$$\mathrm{e}\mathrm{V}$. The instrument features a tracker built from more than one thousand lithium-drifted silicon detectors, each read out by a dedicated custom integrated circuit. With the first flight scheduled for the austral summer of 2025, a new prototype chip, ANTARES4, has been developed using a commercial 65 $\mathrm{n}$$\mathrm{m}$ complementary metal-oxide semiconductor process for use in the second flight. It integrates eight independent analog channels, each incorporating a low-noise charge-sensitive amplifier with dynamic signal compression, a CR–RC shaping stage with eight selectable peaking times, and on-chip calibration circuitry. The charge-sensitive amplifier uses metal-oxide semiconductor feedback elements with voltage-dependent capacitance to support the wide input energy range from 10 $\mathrm{k}$$\mathrm{e}\mathrm{V}$ to 100 $\mathrm{M}$$\mathrm{e}\mathrm{V}$. Four alternative feedback implementations are included to compare performance and design trade-offs. Leakage current compensation up to 200 $\mathrm{n}$$\mathrm{A}$ per detector strip is provided by a Krummenacher current–feedback network. This paper presents the design and architecture of ANTARES4, highlighting the motivations, design drivers, and performance requirements that guided its development. Full article

Sodium-ion batteries (SIBs) are gaining attention in research and industry as a sustainable alternative to lithium-ion batteries (LIBs). However, the advantages of sodium over lithium in terms of accessibility, price, and environmental impact are currently not fully exploited because of inexperience in production, leading to inhomogeneities in their behavior. Using electrical (e.g., open-circuit voltage curve (OCV), electrochemical impedance spectroscopy) and non-electrical measurement methods (e.g., laser scanning microscopy, computed tomography), three widely used LIB technologies and one SIB technology, all with the same rated capacity (1500 mAh) and format (18650), are compared in this article. The study reveals significant differences, such as a 12% lower cell weight at the same rated capacity of the SIB using less windings in the jelly roll, as well as a high energy density cell configuration and a much more severe dependency of the discharge capacity on temperature, exceeding the LIBs by at least a factor of 5. Additionally, the impedance of the SIB differs due to slower ion kinetics on the electrodes, showing relevant differences in both the frequency behavior and the pulse relaxation to the LIBs. An OCV reconstruction indicates the sparsity in the available literature data and the necessity to further investigate the characteristics of the SIB to validate it as a drop-in technology on the market. Full article

We present a time-domain direct current (DC) approach to differentiate positive- (PE) and negative-electrode (NE) contributions from two-electrode full-cell signals in lithium-ion batteries, enabling electrode-resolved diagnostics without specialized instrumentation. The responses of a LiNi_0.8Co_0.1Mn_0.1O₂ (PE)/graphite (NE) cell were recorded across −20 to 20 °C during galvanostatic pulses and subsequent open-circuit relaxations, alongside electrochemical impedance spectroscopy (EIS) measurements. These responses were analyzed using an equivalent-circuit-based model to decompose them into terms with characteristic times. Their distinct temperature dependences enabled attribution of the dominant terms to PE or NE, especially at low temperatures where temporal separation is substantial. The electrode attribution and activation energies were cross-validated against three-electrode measurements and were consistent with EIS-derived time constants. Reconstructing full-cell voltage transients from the identified terms reproduced the measured electrode-specific behavior, and quantitative comparisons showed that the DC time-domain separation aligned closely with directly measured PE/NE overpotentials during the current pulse. These results demonstrate a practical pathway to extract electrode-resolved information from cell voltage alone, offering new methodological possibilities for battery diagnostics and management while complementing three-electrode and alternating current (AC) techniques that are often constrained in field applications. Full article

Hydroelectricity energy harvesting has emerged as a promising, eco-friendly alternative for addressing the growing demand for sustainable energy solutions. In this study, we present a hydroelectricity energy harvester fabricated from shredded waste printing paper (WPP), offering a novel waste-to-energy conversion strategy that requires neither material purification nor complex processing. The device leverages the randomly entangled fiber network of WPP to facilitate capillary-driven moisture diffusion and electric double layer (EDL) formation, thereby enabling efficient electrokinetic energy conversion. The random arrangement of WPP fibers increases the effective EDL area, allowing the waste printing paper generator (WPPG) to achieve an open-circuit voltage of 0.372 V and a short-circuit current of 135 μA at room temperature under optimized electrolyte conditions. This study demonstrates that carbon-black-coated WPP can be effectively upcycled into a high-performance hydroelectricity generator, exhibiting excellent electrical output at ambient conditions. By combining material recycling with efficient energy conversion, this system establishes a practical and sustainable pathway for distributed power generation. Overall, this work not only presents an environmentally responsible approach to device fabrication but also highlights that hydroelectricity energy harvesting using WPPG represents a promising alternative energy route for future applications. Full article