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Keywords = al-Andalus

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22 pages, 514 KB  
Article
Orality, Liturgy, and Transcendence in Ḥafṣ Ibn Albar’s Kitāb al-Zabūr (889 CE)
by Jason Busic
Religions 2026, 17(5), 541; https://doi.org/10.3390/rel17050541 - 30 Apr 2026
Viewed by 165
Abstract
Perhaps the most well-known figure from among the Arabized Christians of al-Andalus, the theologian and scholar Ḥafṣ Ibn Albar of Cordoba (fl. late ninth/early tenth century CE) has attracted considerable scholarly attention. The work that has drawn the most attention, extant in its [...] Read more.
Perhaps the most well-known figure from among the Arabized Christians of al-Andalus, the theologian and scholar Ḥafṣ Ibn Albar of Cordoba (fl. late ninth/early tenth century CE) has attracted considerable scholarly attention. The work that has drawn the most attention, extant in its entirety, is Ibn Albar’s translation into the classical Arabic meter of rajaz of Jerome’s Latin Psalter, rendered from the Hebrew. Most scholars have focused on this text as a lens into Arabization and Islamization among Iberian Christians and the impact of acculturation on Christian doctrine. However, the relationship between poetic form and liturgical practice in Ibn Albar’s translation has received less attention. In the present article, I explore this relationship. I offer a close reading of Kitāb al-Zabūr in dialogue with its Vorlagen, the Old Hispanic liturgy, and Qurʾānic recitation. I argue that Ibn Albar’s translation exploits and amplifies the characteristic orality of its sources and communicates the Psalms principally as liturgical practice, ad intra and ad extra. I conclude that Ibn Albar’s Psalter reinforces Latin Christian tradition while also transcending it. Full article
26 pages, 9276 KB  
Article
Multi-Stage Statistical Approach for PM2.5 Source Identification in Baghdad
by Omar S. Noaman, Alison S. Tomlin and Hu Li
Atmosphere 2026, 17(5), 455; https://doi.org/10.3390/atmos17050455 - 29 Apr 2026
Viewed by 185
Abstract
Although prior research focused on Baghdad has identified variability in fine particulate matter concentrations (PM2.5) and their origins, there remains uncertainty in the identification of the relative importance of local and long-range PM2.5 sources. This study analysed hourly air pollutant [...] Read more.
Although prior research focused on Baghdad has identified variability in fine particulate matter concentrations (PM2.5) and their origins, there remains uncertainty in the identification of the relative importance of local and long-range PM2.5 sources. This study analysed hourly air pollutant concentrations and meteorological data from three monitoring sites over the year 2019 in Baghdad, namely Al-Wazeriya (WZ), Al-Andalus Square (AS), and Al-Saiydiya (SA) sites, to determine the nature of PM2.5 sources. Multi-stage statistical models were utilised to address inherent data limitations and varying sampling dates caused by limitations on power supplies to monitoring equipment, thus improving the identification of urban particulate sources. Bivariate polar plots, concentration ratios, and conditional bivariate probability function (CBPF) plots were used to identify local sources of PM2.5. Potential Source Contribution Function (PSCF) and concentration weighted trajectory (CWT) methods were employed for distant and regional source apportionment. Domestic diesel generators are suggested to be the primary local source of PM2.5 pollutants in Baghdad’s WZ area (categorised as residential with significant traffic volumes). Gasoline- and diesel-fueled motor vehicles significantly contribute to PM2.5 concentrations in the AS and SA areas, which are commercial areas with the latter having close proximity to motorway sources. Additional impacts result from gas flaring and thermal power plants in these regions. Long-range PM2.5 transport may be attributed to the combustion of low-quality heavy fuel oils from several potential sources, including Nahrawan brick factories, oil fields, and Al-Musayyab thermal power plants, primarily towards the northeast, east, and southeast of Baghdad. Transboundary contributions to PM2.5 concentrations in Baghdad were also identified, from industrial sources in western Iran and eastern Syria, as well as dust particulates, and oil and gas production from southwestern Iran’s Khuzestan Province, Kuwait, and the Arabian Gulf. Low to medium wind speeds (1–4 ms−1) were linked with the highest source contributions, suggesting local emission sources to be the most significant contributors to high PM2.5 at the studied sample locations. Full article
(This article belongs to the Special Issue Advances in Air Quality Monitoring and Source Apportionment)
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27 pages, 4244 KB  
Article
Low-Voltage Blood Component Separation for Implantable Kidneys Using a Sawtooth Electrode and Negative Dielectrophoresis
by Hasan Mhd Nazha, Mhd Ayham Darwich, Al-Hasan Ali and Basem Ammar
Appl. Sci. 2026, 16(6), 2785; https://doi.org/10.3390/app16062785 - 13 Mar 2026
Viewed by 399
Abstract
Implantable artificial kidneys represent a promising alternative for patients with end-stage renal disease (ESRD), aiming to overcome the limitations of conventional dialysis through the integration of microfluidic and electrokinetic technologies. In this study, we present a sawtooth electrode microfluidic chamber that achieves blood [...] Read more.
Implantable artificial kidneys represent a promising alternative for patients with end-stage renal disease (ESRD), aiming to overcome the limitations of conventional dialysis through the integration of microfluidic and electrokinetic technologies. In this study, we present a sawtooth electrode microfluidic chamber that achieves blood cell separation via negative dielectrophoresis at a record-low operating voltage of 1.4 V, representing a fivefold reduction compared with rectangular electrode designs and supporting potential integration into implantable artificial kidney systems. A microfluidic chip incorporating an asymmetric sawtooth electrode geometry was developed to enhance local electric field gradients while reducing power consumption. Device performance was investigated using COMSOL Multiphysics simulations. Response Surface Methodology (RSM) based on a Box–Behnken design was employed to optimize the number of teeth per unit length (N), sawtooth height (H), and applied voltage (V), while excitation frequency was fixed at 1 MHz and flow velocity was maintained constant at 0.1 µL·min−1. Statistical analysis was conducted using analysis of variance (ANOVA) in Minitab (Version 27; Minitab, LLC, State College, PA, USA, 2024). The optimization model showed strong predictive capability (R2 = 95.8%) and identified applied voltage (59.45% contribution) and sawtooth height (33%) as the dominant factors affecting separation efficiency, with a significant H × V interaction (p = 0.023). Comprehensive voltage-response mapping over the range of 0.8–4.0 V revealed four operational regimes, including a previously unreported high-voltage failure zone above 2.8 V, where electrothermal flow and electroporation degrade performance. Under physiological conductivity conditions, the optimized design maintained a separation efficiency of 78.3% at 1.4 V with a tip temperature rise of only 1.2 °C, while full recovery of performance was achieved at 2.2 V. Cell-specific separation efficiencies reached 97.3% for white blood cells, 95.8% for red blood cells, and 84.7% for platelets, reducing the downstream cellular load by 92.6%. These findings demonstrate that the proposed low-voltage, high-efficiency separation platform has strong potential as a cellular pre-filtration module in implantable artificial kidney systems and other lab-on-chip biomedical devices. Full article
(This article belongs to the Special Issue Advances in Materials for Biosensing and Biomedical Applications)
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15 pages, 1798 KB  
Article
Enhancement of Flame Resistance of Cotton Fabrics Using Multilayer Biomaterial Coatings of Chitosan and Sodium Alginate
by Hasan Mhd Nazha, Thaer Osman, Mayssa Shash and Layal Mohammed
Coatings 2026, 16(3), 311; https://doi.org/10.3390/coatings16030311 - 3 Mar 2026
Viewed by 555
Abstract
Cotton fabrics are widely used in textiles due to their comfort and breathability, but their high flammability (limiting oxygen index (LOI) ≤ 18%) poses serious safety risks. While conventional flame-retardant treatments often rely on synthetic chemicals or toxic additives, biobased alternatives remain underdeveloped. [...] Read more.
Cotton fabrics are widely used in textiles due to their comfort and breathability, but their high flammability (limiting oxygen index (LOI) ≤ 18%) poses serious safety risks. While conventional flame-retardant treatments often rely on synthetic chemicals or toxic additives, biobased alternatives remain underdeveloped. The flame resistance of cotton fabrics may be enhanced using multilayer biocoatings of chitosan and sodium alginate applied via layer-by-layer (LBL) assembly—a sustainable and scalable approach. Cotton samples were coated with chitosan and sodium alginate bilayers (1, 2, 5, and 10 layers) using the LBL method. Flame resistance was evaluated using vertical flame tests and limiting oxygen index (LOI) testing according to ASTM D2863-09. The sample coated with 10 bilayers significantly outperformed uncoated cotton and lower-layer samples. With a char length of 9.72 cm (68% reduction), no dripping was observed in the vertical flame tests, and the LOI value was 23.47% compared to uncoated cotton (LOI = 18.04%). These improvements were attributed to the formation of a cohesive and protective carbon layer, which is likely capable of inhibiting the formation of flammable gases. Biomaterial multilayer coatings made from biomaterials, such as chitosan and sodium alginate, represent a promising and environmentally friendly alternative to traditional methods in improving cotton’s flame resistance. The development of this technology points to potential applications in protective textiles and industrial safety clothing. Notably, chitosan and sodium alginate coatings are biocompatible. The term “biomaterials” refers to materials intended for interaction with biological systems, particularly for biomedical-related applications. The term “biobased materials” is used exclusively to describe materials derived from renewable biological sources. Full article
(This article belongs to the Section Bioactive Coatings and Biointerfaces)
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24 pages, 2416 KB  
Article
A Hybrid Machine Learning Framework for Multi-Pollutant Air Quality Assessment in Urban Environments
by Muzzamil Mustafa, Maaz Akhtar, Ashfaq Ahmad, Fahad Javaid, Barun Haldar and Badil Nisar
Sustainability 2026, 18(4), 2148; https://doi.org/10.3390/su18042148 - 22 Feb 2026
Viewed by 748
Abstract
Urban air quality assessment is central to environmental sustainability and public health management. This study presents a structured comparative evaluation of Random Forest (RF), Support Vector Machine (SVM), LSTM, and Bi-LSTM models for pollutant-driven air quality classification under the Indian National Air Quality [...] Read more.
Urban air quality assessment is central to environmental sustainability and public health management. This study presents a structured comparative evaluation of Random Forest (RF), Support Vector Machine (SVM), LSTM, and Bi-LSTM models for pollutant-driven air quality classification under the Indian National Air Quality Index (NAQI) framework defined by CPCB guidelines. To provide a fair comparison, multi-pollutant data of Indian urban monitoring stations were preprocessed, and the class-balancing protocol and validation protocol were combined. RF had highest total accuracy (0.9971) in the held-out set, with Bi-LSTM (0.9615), LSTM (0.9495), and SVM (0.9442) coming next. Although ensemble methods proved to be very separable in line with the threshold-based NAQI structure, Bi-LSTM was more stable when it came to boundary-sensitive switches among the adjacent severity classes. Calibration analysis (multiclass Brier score: 0.08) showed consistent probabilistic behavior and interpretation, and using SHAP showed physically significant pollutant driving factors. The results explain the appropriateness of comparative models in organized AQI classification and present a reproducible assessment framework for the NAQI framework. Full article
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38 pages, 14249 KB  
Article
Reassessing an Early Medieval Rural Mosque in Al-Andalus: New Insights from Building Archaeology Analysis of the Cortijo de Las Mezquitas (Málaga, Spain)
by María de los Ángeles Utrero Agudo, Angelo Castrorao Barba, José Ignacio Murillo Fragero, Enrique Álvarez Areces and Pedro Gurriarán Daza
Heritage 2026, 9(1), 26; https://doi.org/10.3390/heritage9010026 - 13 Jan 2026
Viewed by 1285
Abstract
Recent investigations at the Cortijo de las Mezquitas complex (Antequera–Campillos–Sierra de Yeguas, Province of Málaga, Andalusia, Spain) have focused on clarifying the construction history of the monument and on contextualising the presence of an early medieval rural mosque, a rare example within the [...] Read more.
Recent investigations at the Cortijo de las Mezquitas complex (Antequera–Campillos–Sierra de Yeguas, Province of Málaga, Andalusia, Spain) have focused on clarifying the construction history of the monument and on contextualising the presence of an early medieval rural mosque, a rare example within the Iberian Peninsula. The reassessment of the complex, conducted within the methodological framework of Building Archaeology, has made it possible to describe the constructive characteristics of the building with greater precision, both in terms of its architectural design and its construction process. This approach has enabled a more detailed definition of the technological context employed in the original construction phase, as well as of the chronological range to which it belongs, spanning between the late ninth and early tenth centuries. Subsequent phases of reoccupation and transformation, particularly from the sixteenth century onwards, were also documented, although the dating of some interventions remains uncertain. This research provides a fundamental framework for the historical contextualisation of the monument within the history of al-Andalus and highlights the urgent need for its conservation, restoration, and valorisation. Full article
(This article belongs to the Special Issue Unveiling the Past: Multidisciplinary Investigations in Archaeology)
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24 pages, 2495 KB  
Article
Bridging Financial Inclusion and Health Equity in LMICs: Evidence from a Half-Century of Bibliometric Data
by Hasan Mhd Nazha, Masah Alomari and Mhd Ayham Darwich
Int. J. Environ. Res. Public Health 2026, 23(1), 96; https://doi.org/10.3390/ijerph23010096 - 10 Jan 2026
Viewed by 764
Abstract
Health equity and financial inclusion (FI) are at the core of the Sustainable Development Goals, yet their intersection remains critically under-studied. This bibliometric study maps this emergent and fragmented field by analyzing 24,140 publications from Scopus, PubMed, Web of Science, and Lens.org over [...] Read more.
Health equity and financial inclusion (FI) are at the core of the Sustainable Development Goals, yet their intersection remains critically under-studied. This bibliometric study maps this emergent and fragmented field by analyzing 24,140 publications from Scopus, PubMed, Web of Science, and Lens.org over five decades. Employing co-citation and co-word analysis via VOSviewer, chart research trends, governance frameworks, and policy linkages were systematically presented. The analysis reveals that less than 0.3% of the identified literature explicitly bridges financial inclusion with health outcomes, and direct investigations into health equity are virtually absent. Despite recent growth, fundamental gaps persist, including a lack of empirical studies on digital financial tools in low- and middle-income countries (LMIC) health contexts and insufficient focus on disadvantaged populations. As the first comprehensive empirical mapping of this nexus, this study underscores the urgency for scholarly and policy action to strategically leverage financial instruments for equitable healthcare access. The findings provide a foundational map and a structured agenda to consolidate this nascent field. Full article
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24 pages, 5754 KB  
Article
Advancing Archaeobotanical Methods: Morphometry, Bayesian Analysis and AMS Dating of Rose Prickles from Monteagudo Almunia, Spain (12th Century–Present)
by Diego Rivera, Julio Navarro, Inmaculada Camarero, Javier Valera, Diego-José Rivera-Obón and Concepción Obón
Plants 2025, 14(24), 3709; https://doi.org/10.3390/plants14243709 - 5 Dec 2025
Viewed by 1013
Abstract
Background: While archaeological evidence is crucial for understanding the origins of ancient rose varieties in Western Europe, the botanical composition of medieval Islamic gardens remains largely unknown. This study focuses on the rose cultivation at the 12th-century Almunia del Castillejo de Monteagudo in [...] Read more.
Background: While archaeological evidence is crucial for understanding the origins of ancient rose varieties in Western Europe, the botanical composition of medieval Islamic gardens remains largely unknown. This study focuses on the rose cultivation at the 12th-century Almunia del Castillejo de Monteagudo in Murcia, Spain, a key Islamic site in al-Andalus. Methods: Morphometric analysis and Bayesian hypothesis testing were applied to characterize rose prickle remains recovered from the site. The prickles were found in stratigraphic contexts above the original garden and yielded post-medieval radiocarbon dates (18th–19th centuries AD). The morphological parameters of the archaeological specimens were statistically compared against reference collections of known rose species to determine their probable botanical origins. Results: The analysis identified two distinct prickle morphotypes. Statistical comparisons indicate these correspond to the white musk rose (Rosa moschata Herrm.) and to yellow roses from the Rosa foetida Herrm. complex (including R. lutea Mill. var. persiana Lem.). Both species are historic introductions from West Asia. The morphometric parameters demonstrated significant diagnostic value for the species-level identification of archaeological rose remains. Conclusion: Despite the post-medieval date of the prickles, the presence of R. moschata and R. foetida suggests the continuity of cultivation for rose species originally already known during the medieval Islamic period. This provides direct archaeological evidence for the role of al-Andalus gardens in the dissemination of West Asian rose diversity, highlighting the lasting impact of medieval Islamic horticulture on the Iberian Peninsula. Full article
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17 pages, 1236 KB  
Article
Beyond Correlation: An Explainable AI Framework for Diagnosing the Contextual Drivers of Financial Inclusion on Universal Health Coverage in the Arab World
by Hasan Mhd Nazha, Mhd Ayham Darwich and Masah Alomari
Computation 2025, 13(11), 269; https://doi.org/10.3390/computation13110269 - 16 Nov 2025
Viewed by 881
Abstract
Universal Health Coverage (UHC) remains a core Sustainable Development Goal challenge for Arab nations, with structural inequalities and conflict ongoing in threatening equal access to health. Although literature concurs on the presence of a relationship between UHC and financial inclusion, contextual mechanisms underpinning [...] Read more.
Universal Health Coverage (UHC) remains a core Sustainable Development Goal challenge for Arab nations, with structural inequalities and conflict ongoing in threatening equal access to health. Although literature concurs on the presence of a relationship between UHC and financial inclusion, contextual mechanisms underpinning this relationship remain poorly understood. This study offers an integrated Explainable AI (XAI)–Econometric methodology to unveil how financial inclusion—through digital as well as physical channels for services—drives UHC progress in 17 Arab nations (2011–2022). With the use of Feasible Generalized Least Squares (FGLS), Panel-Corrected Standard Errors (PCSE), and Random Forest regression with SHAP (SHapley Additive exPlanations) values, we estimate both average causal and heterogeneous contextual effects. The combined model increases predictive strength by 18% over conventional econometric baselines (R2 = 0.83), while the SHAP results identified top predicators. The findings suggest that ATM density and electricity access remain the overriding drivers of UHC whereas digital financial services play a role only with the complement of strong public health expenditures. The diagnostic result allows policymakers to designate country-specific challenges and prioritize joint investments in infrastructure and inclusive finance. While data constraints in conflict settings need cautious interpretation, the proposed XAI–econometric strategy supplies a replicable methodology template for contextualized SDG diagnostics. Full article
(This article belongs to the Section Computational Social Science)
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13 pages, 1555 KB  
Article
Quantitative Evaluation of Vacuum-Induced Morphological Changes in Knee-Disarticulation: A Case Study for Personalized Prosthetic Socket Design
by Mhd Ayham Darwich, Hasan Mhd Nazha, Kaysse Ibrahim, Lourance Kamleh, Maysaa Shash and Ebrahim Ismaiel
Symmetry 2025, 17(10), 1719; https://doi.org/10.3390/sym17101719 - 13 Oct 2025
Viewed by 1782
Abstract
Achieving a best-fit prosthetic socket is essential to comfort, functional performance, and long-term residual limb health in lower-limb amputees. To our knowledge, no previous study has quantitatively compared in vivo residual limb geometry under vacuum versus non-vacuum conditions using high-resolution computed tomography (CT). [...] Read more.
Achieving a best-fit prosthetic socket is essential to comfort, functional performance, and long-term residual limb health in lower-limb amputees. To our knowledge, no previous study has quantitatively compared in vivo residual limb geometry under vacuum versus non-vacuum conditions using high-resolution computed tomography (CT). In this patient-specific case study of a bilateral knee-disarticulation (KD) amputee, both residual limbs were scanned under standardized conditions: one enclosed in a vacuum-compressed sleeve and the contralateral limb untreated as a natural control, thereby minimizing inter-subject variability. CT-based 3D reconstructions enabled volumetric and cross-sectional quantification, including symmetry/asymmetry analysis of paired limbs, while finite element analysis (FEA) assessed the biomechanical consequences for socket performance. Vacuum application resulted in a 4.1% reduction in total limb volume and a 5.3% reduction in mid-thigh cross-sectional area, with regionally asymmetric displacement of soft tissues. FEA demonstrated that vacuum-induced geometry reduced peak Von Mises stresses (27.43 MPa to 15.83 MPa), minimized maximum displacement (1.72 mm to 0.88 mm), and improved minimum factor of safety (~2.0 to ~3.0), while homogenizing contact pressure distribution (peak fell from 2.42 to 1.28 N/mm2). These findings provide preliminary CT-based evidence that vacuum application induces measurable morphological adaptations with implications for socket conformity, comfort, and load transfer. While limited to a single patient, this study highlights the potential of vacuum-induced modeling to inform personalized prosthetic socket design. Full article
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32 pages, 3110 KB  
Article
Persistence and Heritage from Medieval Bustān Gardens: Roses in Ancient Western Islamic Contexts and Abandoned Rural Gardens of Spain
by Diego Rivera, Julio Navarro, Inmaculada Camarero, Javier Valera, Diego-José Rivera-Obón and Concepción Obón
Heritage 2025, 8(8), 315; https://doi.org/10.3390/heritage8080315 - 7 Aug 2025
Cited by 2 | Viewed by 5261
Abstract
Medieval Islamic bustān gardens in the western Mediterranean played a crucial role in preserving and enriching rose diversity through the cultivation of species from the eastern Mediterranean and western Asia. These gardens, particularly in Al-Andalus, maintained distinctive rose varieties characterized by diverse flower [...] Read more.
Medieval Islamic bustān gardens in the western Mediterranean played a crucial role in preserving and enriching rose diversity through the cultivation of species from the eastern Mediterranean and western Asia. These gardens, particularly in Al-Andalus, maintained distinctive rose varieties characterized by diverse flower morphology—ranging from white to deep crimson and near-black hues, including various yellow shades—and complex fragrance profiles with multiple olfactory nuances. The botanical heritage from these medieval Islamic gardens demonstrates remarkable persistence, with several of these cultivated rose species still found today in abandoned cortijos and aldeas throughout the mountains of eastern Spain. This study examines the transmission of rose culture through medieval Islamic bustān gardens, analyzing how these gardens served as repositories for ancient cultivars while introducing new varieties from eastern regions. Through examination of historical texts, iconographic evidence, and field documentation of surviving populations, we trace the continuity of medieval Islamic rose cultivation practices and their lasting impact on the rural landscape of eastern Spain. Flower scent is prominent as the leading factor determining preferences for medieval heritage rose cultivars, together with color and shape. The survival of these roses in abandoned settlements provides unique insight into the durability of medieval horticultural systems and the adaptation of cultivated species to semi-wild conditions over centuries. Full article
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20 pages, 7704 KB  
Article
Laser Scanning and Photogrammetry for Graphic Analysis and Heritage Documentation: The Lopera Tower, a 14th-Century Castilian Fortress
by Juan Francisco Molina Rozalem, Jesús Rodríguez Medina and Ignacio Acosta
Appl. Sci. 2025, 15(15), 8737; https://doi.org/10.3390/app15158737 - 7 Aug 2025
Cited by 1 | Viewed by 1392
Abstract
Spain is among the European countries with the greatest number of preserved castles and defensive structures—some estimates place the total at around 10,000, the majority of which date back to the medieval period. Yet, surprisingly, many of these fortifications remain uncatalogued and in [...] Read more.
Spain is among the European countries with the greatest number of preserved castles and defensive structures—some estimates place the total at around 10,000, the majority of which date back to the medieval period. Yet, surprisingly, many of these fortifications remain uncatalogued and in an advanced state of ruin. This study focuses on a small fortress that has been overlooked by historiography and neglected by public authorities, yet which still stands after seven centuries: the Tower of Lopera, a castle belonging to the so-called Banda Morisca (the frontier of Al-Andalus in the 14th century). Using a combination of digital documentation techniques—namely, portable laser scanning, photogrammetry (via drone and camera), and digital image processing software—we have been able to digitize, geometrize, and document both the surviving architectural remains and their immediate physical environment. Rather than pursuing the latest technological innovations, this methodology prioritizes practical and realistic solutions based on the resources typically available to cultural heritage administrations. Our work serves two main objectives: to demonstrate the viability of applying such tools to this typology of architectural heritage and to conduct a detailed graphic and geometric analysis of the structure. Given the abundance of similar abandoned fortresses in Spain, the findings presented here could inform future heritage documentation strategies on a broader, potentially national, scale. Full article
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8 pages, 2222 KB  
Proceeding Paper
Advanced 3D Polymeric Sponges Offer Promising Solutions for Addressing Environmental Challenges in Qatar’s Marine Ecosystems
by Mohamed Helally, Mostafa H. Sliem and Noora Al-Qahtani
Mater. Proc. 2025, 22(1), 4; https://doi.org/10.3390/materproc2025022004 - 18 Jul 2025
Cited by 2 | Viewed by 985
Abstract
The increasing incidence of oil contamination in many aquatic ecosystems, particularly in oil-rich regions such as Qatar, poses significant threats to marine life and human activities. Our study addresses the critical need for effective and eco-friendly oil-water separation techniques, focusing on developing graphene [...] Read more.
The increasing incidence of oil contamination in many aquatic ecosystems, particularly in oil-rich regions such as Qatar, poses significant threats to marine life and human activities. Our study addresses the critical need for effective and eco-friendly oil-water separation techniques, focusing on developing graphene and chitosan-based three-dimensional (3D) polymeric sponges. These materials have demonstrated potential due to their high porosity and surface area, which can be enhanced through surface treatment to improve hydrophobicity and oleophilicity. This study introduces a new technique dependent on the optimization of the graphene oxide (GO) concentration within the composite sponge to achieve a superior oil uptake capacity (51.4 g oil/g sponge at 3% GO), and the detailed characterization of the material’s performance in separating heavy oil-water emulsions. Our study seeks to answer key questions regarding the performance of these modified sponges and their scalability for industrial applications. This research directly aligns with Qatar’s environmental goals and develops sustainable oil-water separation technologies. It addresses the pressing challenges of oil spills, ultimately contributing to improved marine ecosystem protection and efficient resource recovery. Full article
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20 pages, 3627 KB  
Article
Biotribological Wear Prediction of Alumina–Polymer Hip Prostheses Using Finite Element Analysis
by Mhd Ayham Darwich, Hasan Mhd Nazha, Hiba Mohsen Ghadir and Ahmad Salamah
Appl. Mech. 2025, 6(3), 46; https://doi.org/10.3390/applmech6030046 - 24 Jun 2025
Cited by 1 | Viewed by 2034
Abstract
This study investigates the biotribological performance of alumina–UHMWPE and alumina–PEEK hip implant couples through finite element simulation (ANSYS v24) and statistical inference (STATA v17). During gait cycle loading simulations, significant disparity in wear behaviour was observed. Alumina–UHMWPE demonstrated superior mechanical resistance, with a [...] Read more.
This study investigates the biotribological performance of alumina–UHMWPE and alumina–PEEK hip implant couples through finite element simulation (ANSYS v24) and statistical inference (STATA v17). During gait cycle loading simulations, significant disparity in wear behaviour was observed. Alumina–UHMWPE demonstrated superior mechanical resistance, with a wear volume of 0.18481 mm3 and a wear depth of 6.93 × 10−4 mm compared to alumina–PEEK, which registered higher wear (volume: 8.4006 mm3; depth: 3.15 × 10−2 mm). Wear distribution analysis indicated alumina–UHMWPE showed an even wear pattern in comparison to the poor, uneven alumina-PEEK high-wear patterns. Statistical comparison validated these findings, wherein alumina–UHMWPE achieved a 27.60 hip joint wear index (HCI) value, which is better than that of alumina–PEEK (35.85 HCI), particularly regarding key parameters like wear depth and volume. This computational–statistical model yields a baseline design for biomaterial choice, demonstrating the potential clinical superiority of alumina–UHMWPE in reducing implant failure risk. While this is a simulation study lacking experimental validation, the results pave the way for experimental and clinical studies for further verification and refinement. The approach enables hip arthroplasty design optimization with maximal efficiency and minimal resource-intensive testing. Full article
(This article belongs to the Collection Fracture, Fatigue, and Wear)
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12 pages, 560 KB  
Systematic Review
Safety and Efficacy of Reduced Dose of Enzalutamide in Patients with Castration-Resistant Prostate Cancer: A Systematic Review
by Zineddine Belabaci, Lucas Mose, Omar El-Taji, Zina Otmani, Zein Alabdin Hannouneh, Issa Mohamad, Thomas Zilli, Osama Mohamad, Nadeem Pervez, Waleed Arafat, Ursula Vogl and Mohamed Shelan
Pharmaceuticals 2025, 18(5), 732; https://doi.org/10.3390/ph18050732 - 16 May 2025
Cited by 2 | Viewed by 2697
Abstract
Objective: To review the efficacy and safety of reduced dose compared to standard dose Enzalutamide treatment for patients with castration-resistant prostate cancer (CRPC). Methods: PubMed, Scopus, Web of Science, and Cochrane databases were searched for randomized controlled trials and cohort studies reporting the [...] Read more.
Objective: To review the efficacy and safety of reduced dose compared to standard dose Enzalutamide treatment for patients with castration-resistant prostate cancer (CRPC). Methods: PubMed, Scopus, Web of Science, and Cochrane databases were searched for randomized controlled trials and cohort studies reporting the use of Enzalutamide in reduced and standard doses in patients with castration-resistant prostate cancer. Searches were limited to articles published in the English language. Outcome assessments included progression-free survival (PFS), overall survival (OS), adverse events, and serum prostate-specific antigen (PSA) response. Results: Ten studies met the inclusion criteria, including 2481 patients treated with Enzalutamide. Seven studies were retrospective cohorts, two were prospective trials, and one was a prospective cohort. No consistent relationship was identified between OS and PFS and the Enzalutamide dosage. Reduced doses of Enzalutamide decreased the incidence of adverse events, particularly among elderly patients. Conclusions: This systematic review suggests that reduced doses of Enzalutamide in CRPC may maintain therapeutic efficacy in selected patients while improving tolerability. However, inconsistent findings and methodological limitations highlight the need for prospective randomized trials to define optimal and individualized dosing strategies. Full article
(This article belongs to the Special Issue Advances in Prostate Cancer Therapeutics)
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