In this work, 13 jet nebulizers, some of which in different configurations, were investigated in order to identify the biopharmaceutical constraints related to the quality attributes of the medicinal products, which affect their safety, efficiency, c...
Antimicrobial resistance (AMR) in bacteria is a critical global health threat, yet the impact of environmental stressors such as aerosolization on resistance remains unclear. We previously showed that aerosolization can induce antibiotic resistance i...
Bacterial genera present in several areas of a pig farm were analyzed using high-throughput sequencing techniques. Samples were collected from the skin and feces of animals, as well as from surfaces, water, and air. The analyses revealed a strong cor...
Different formulation techniques have been investigated to prepare highly aerosolizable dry powders to deliver a high dose of antibiotics to the lung for treating local infections. In this study, we investigated the influence of the co-amorphization...
Nanoparticles (NPs) can be released in the air in work settings, but various factors influence the exposure of workers. Controlled inhalation experiments can thus be conducted in an attempt to reproduce real-life exposure conditions and assess inhala...
The endothelialization of gas exchange membranes can increase the hemocompatibility of extracorporeal membrane oxygenators and thus become a long-term lung replacement option. Cell seeding on large or uneven surfaces of oxygenator membranes is challe...
6 May 2022
Compost is an important source of airborne fungi that can adversely affect occupational health. However, the aerosol behavior of fungi and their underlying factors in composting facilities are poorly understood. We collected samples from compost pile...
Physico-chemical properties of lactose are key factors in adhesive mixtures used as dry powder inhaler (DPI). Despite the abundant literature on this topic, the effect of the polymorphism and pseudo-polymorphism of lactose has been seldom investigate...
Background: Immunogenicity refers to the inherent ability of a molecule to stimulate an immune response. Aggregates are one of the major risk factors for the undesired immunogenicity of therapeutic antibodies (Ab) and may ultimately result in immune-...
Aspergillus versicolor is ubiquitous in the environment and is particularly abundant in damp indoor spaces. Exposure to Aspergillus species, as well as other environmental fungi, has been linked to respiratory health outcomes, including asthma, aller...
It is now well established that biological pollution is a major cause of the degradation of indoor air quality. It has been shown that microbial communities from the outdoors may significantly impact the communities detected indoors. One can reasonab...
Water quality should be tested to ensure it is acceptable for the healthy growth of plants and animals, and water hardness is one of the important testing indexes. Herein, a novel approach was proposed to achieve high accuracy and rapid quantitative...
An immunosuppressive microenvironment in lung concurs to pre-malignant lesions progression to cancer. Here, we explore if perturbing lung microbiota, which contribute to immunosuppression, by antibiotics or probiotic aerosol interferes with lung canc...
This study presents the spectral monthly and seasonal variation of aerosol optical depth (τAOD), single scattering albedo (SSA), and aerosol absorption optical depth (AAOD) between 2010 and 2018 obtained from the Aerosol Robotic Network (AERONET)...
Dental aerosol-generating procedures produce a large amount of splatters and aerosols that create a major concern for airborne disease transmission, such as COVID-19. This study established a method to visualise splatter and aerosol contamination by...
In this study, hydroxypropyl-beta-cyclodextrin (HP-β-CD) particles were produced using supercritical assisted atomization (SAA) with carbon dioxide as the spraying medium or co-solute and aqueous ethanol solution as the solvent. The effects of severa...
Producing a global and comprehensive description of atmospheric aerosols requires integration of ground-based, airborne, satellite and model datasets. Due to its complexity, aerosol monitoring requires the use of several data records with complementa...
This study investigated the development and characterization of leucine and magnesium stearate (MgSt) embedded wet milled inhalable ibuprofen (IBF) dry powder inhaler (DPI) formulations. IBF microparticles were prepared by a wet milling homogenizatio...
Chemical processing of organic material in aqueous atmospheric aerosols and cloudwater is known to form secondary organic aerosols (SOA), although the extent to which each of these processes contributes to total aerosol mass is unclear. In this study...
To establish the direct climatic and environmental effect of anthropogenic aerosols in East Asia in winter under external, internal, and partial internal mixing (EM, IM and PIM) states, a well-developed regional climate–chemical model RegCCMS i...
The characteristics of aerosol optical depth (AOD) over the Tibetan Plateau (TP) were analyzed using 8-year (from January 2007 to December 2014) Cloud-Aerosol LiDAR and Infrared Pathfinder Satellite Observation (CALIPSO) level 2 aerosol layer product...
Nuclear accidents and decommissioning in the nuclear industry would release a large number of radioactive aerosols which endangers the natural environment and the health of workers. Therefore, there is an urgent need for environment-friendly aerosol...
When retrieving Aerosol Optical Depth (AOD) from passive satellite sensors, the vertical distribution of aerosols usually needs to be assumed, potentially causing uncertainties in the retrievals. In this study, we use the Moderate Resolution Spectror...
The prescribed anthropogenic aerosol forcing recommended by Coupled Model Intercomparison Project Phase 6 (CMIP6) was implemented in an atmospheric model. With the reduced complexity of anthropogenic aerosol forcing, each component of anthropogenic a...
Owing to its ability to produce dense thick-films at room temperature directly from a ceramic powder, the Aerosol Deposition Method (AD) possesses a unique feature in ceramics processing. For this technology, the aerosol generation of particles is a...
Aerosol optical depth (AOD) measurements for 2017–2020 in urban Hohhot of the Mongolian plateau, a transition zone between the depopulated zone and East Asian urban agglomeration, were analyzed for the first time. Results show that annual AOD50...
We verified an algorithm using multi-wavelength Mie-Raman lidar (MMRL) observations to retrieve four aerosol components (black carbon (BC), sea salt (SS), air pollution (AP), and mineral dust (DS)) with in-situ aerosol measurements, and determined th...
Columnar aerosol volume size distributions from March 2012 to February 2013 in Wuhan, China, were investigated with a focus on monthly and seasonal variations in the aerosol optical depths (AODs) and Ångström exponents. AOD is wavelength dependent, a...
The Ultra-Violet Aerosol Index (UVAI) is a practical parameter for detecting aerosols that absorb UV radiation, especially where other aerosol retrievals fail, such as over bright surfaces (e.g., deserts and clouds). However, typical UVAI retrieval r...
The effective radiative forcing (ERF) of anthropogenic aerosol can be more representative of the eventual climate response than other radiative forcing. We incorporate aerosol–cloud interaction into the Chinese Academy of Sciences Flexible Glob...
As one of the main drivers for climate change, it is important to understand changes in anthropogenic aerosol emissions and evaluate the climate impact. Anthropogenic aerosols have affected global climate while exerting a much larger influence on reg...
The retrieval of the aerosol optical thickness (AOT) from remotely-sensed data relies on the adopted aerosol model. However, the method of this technique has been rather limited because of the high variability of the surface albedo, in addition to th...
During August 2016, a quasi-stationary high-pressure system spreading over Central and North-Eastern Europe, caused weather conditions that allowed for 24/7 observations of aerosol optical properties by using a complex multi-wavelength PollyXT lidar...
Accurate and updated aerosol optical properties (AOPs) are of vital importance to climatology and environment-related studies for assessing the radiative impact of natural and anthropogenic aerosols. We comprehensively studied the columnar AOP observ...
Aerosols play an important role in climate change, and ground aerosols (e.g., fine particulate matter, abbreviated as PM2.5) are associated with a variety of health problems. Due to clouds and high reflectance conditions, satellite-derived aerosol op...
Beijing is one of the largest metropolitan areas in the world with relatively high aerosol loading. The population of Beijing is approximately 21.5 million based on statistics from 2014. In order to improve the air quality of Beijing by monitoring an...
Aerosols play an important role in global meteorology and climate, as well as in air transport and human health, but there are still many unknowns on their effects and importance, in particular for the coarser (giant and ultragiant) aerosol particles...
The Poland-AOD aerosol research network was established in 2011 to improve aerosol–climate interaction knowledge and provide a real-time and historical, comprehensive, and quantitative database for the aerosol optical properties distribution ov...
The Modern-Era Retrospective Analysis for Research and Applications, version 2 (MERRA-2) provides data at 0.5° × 0.625° resolution covering a period from 1 January 1980 to the present. Natural and anthropogenic aerosols are simulated in...
Aerosol types in Asian capital cities were classified using a random forest (RF) satellite-based aerosol classification model during 2018–2020 in an investigation of the contributions of aerosol types, with or without Aerosol Robotic Network (AERONET...
In this study, we evaluate aerosol, cloud, and radiation interactions in GFS.V17.p8 (Global Forecast System System Version 17 prototype 8). Two experiments were conducted for the summer of 2020. In the control experiment (EXP CTL), aerosols interact...
Long-term ground-based measurements of aerosol optical properties in Athens, Greece, for the period 2008–2018 performed by the National Observatory of Athens are used in order to investigate the aerosol climatology of the area. In this study, w...
Different aerosol types exhibit distinct radiative effects in different regions, attributed to their unique optical characteristics and regional distributions. This study focuses on North China, which is impacted by both natural and anthropogenic aer...
In this work, we report the ongoing implementation of online-coupled aerosol–cloud microphysical–radiation interactions in the Brazilian global atmospheric model (BAM) and evaluate the initial results, using remote-sensing data for JFM 20...
The first Visible Infrared Imaging Radiometer Suite (VIIRS) was launched on Suomi National Polar-orbiting Partnership (S-NPP) satellite in late 2011. Similar to the Moderate resolution Imaging Spectroradiometer (MODIS), VIIRS observes top-of-atmosphe...
This study presents a global aerosol climatology derived from six years (October 2018–October 2024) of the Ice, Cloud, and land Elevation Satellite-2 (ICESat-2) observations, using a U-Net Convolutional Neural Network (CNN) machine learning alg...
The composition and oxidation state of aerosol iron were examined using synchrotron-based iron near-edge X-ray absorption spectroscopy. By combining synchrotron-based techniques with water leachate analysis, impacts of oxidation state and mineralogy...
The aim of this study is to evaluate the accuracy of MODerate resolution Imaging Spectroradiometer (MODIS) aerosol optical depth (AOD) products over heavy aerosol loading areas. For this analysis, the Terra-MODIS Collection 6.1 (C6.1) Dark Target (DT...
Nocardia, an easily missed but potentially fatal opportunistic pathogen, can lead to serious infections like lung and brain abscesses. Intranasal inoculation (IN) is the traditional approach for constructing a Nocardia-induced pneumonia mice model, w...
Default aerosol extinction coefficient profiles are commonly used instead of measured profiles in radiative transfer modeling, increasing the uncertainties in the simulations. The present study aimed to determine the magnitude of these uncertainties...
of 115