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Search Results (508)

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20 pages, 1788 KiB  
Article
Legume–Cereal Cover Crops Improve Soil Properties but Fall Short on Weed Suppression in Chickpea Systems
by Zelalem Mersha, Michael A. Ibarra-Bautista, Girma Birru, Julia Bucciarelli, Leonard Githinji, Andualem S. Shiferaw, Shuxin Ren and Laban Rutto
Agronomy 2025, 15(8), 1893; https://doi.org/10.3390/agronomy15081893 - 6 Aug 2025
Abstract
Chickpea is a highly weed-prone crop with limited herbicide options and high labor demands, raising the following question: Can fall-planted legume–cereal cover crops (CCs) improve soil properties while reducing herbicide use and manual weeding pressure? To explore this, we evaluated the effect of [...] Read more.
Chickpea is a highly weed-prone crop with limited herbicide options and high labor demands, raising the following question: Can fall-planted legume–cereal cover crops (CCs) improve soil properties while reducing herbicide use and manual weeding pressure? To explore this, we evaluated the effect of fall-planted winter rye (WR) alone in 2021 and mixed with hairy vetch (HV) in 2022 and 2023 at Randolph farm in Petersburg, Virginia. The objectives were two-fold: (a) to examine the effect of CCs on soil properties using monthly growth dynamics and biomass harvested from fifteen 0.25 m2-quadrants and (b) to evaluate the efficiency of five termination methods: (1) green manure (GM); (2) GM plus pre-emergence herbicide (GMH); (3) burn (BOH); (4) crimp mulch (CRM); and (5) mow-mulch (MW) in suppressing weeds in chickpea fields. Weed distribution, particularly nutsedge, was patchy and dominant on the eastern side. Growth dynamics followed an exponential growth rate in fall 2022 (R2 ≥ 0.994, p < 0.0002) and a three-parameter sigmoidal curve in 2023 (R2 ≥ 0.972, p < 0.0047). Biomass averaged 55.8 and 96.9 t/ha for 2022 and 2023, respectively. GMH consistently outperformed GM in weed suppression, though GM was not significantly different from no-till systems by the season’s end. Kabuli-type chickpeas under GMH had significantly higher yields than desi types. Pooled data fitted well to a three-parametric logistic curve, predicting half-time to 50% weed coverage at 35 (MM), 38 (CRM), 40 (BOH), 46 (GM), and 53 (GMH) days. Relapses of CCs were consistent in no-till systems, especially BOH and MW. Although soil properties improved, CCs alone did not significantly suppress weed. Full article
(This article belongs to the Section Weed Science and Weed Management)
24 pages, 4796 KiB  
Article
Comprehensive Experimental Optimization and Image-Driven Machine Learning Prediction of Tribological Performance in MWCNT-Reinforced Bio-Based Epoxy Nanocomposites
by Pavan Hiremath, Srinivas Shenoy Heckadka, Gajanan Anne, Ranjan Kumar Ghadai, G. Divya Deepak and R. C. Shivamurthy
J. Compos. Sci. 2025, 9(8), 385; https://doi.org/10.3390/jcs9080385 - 22 Jul 2025
Viewed by 285
Abstract
This study presents a multi-modal investigation into the wear behavior of bio-based epoxy composites reinforced with multi-walled carbon nanotubes (MWCNTs) at 0–0.75 wt%. A Taguchi L16 orthogonal array was employed to systematically assess the influence of MWCNT content, load (20–50 N), and sliding [...] Read more.
This study presents a multi-modal investigation into the wear behavior of bio-based epoxy composites reinforced with multi-walled carbon nanotubes (MWCNTs) at 0–0.75 wt%. A Taguchi L16 orthogonal array was employed to systematically assess the influence of MWCNT content, load (20–50 N), and sliding speed (1–2.5 m/s) on wear rate (WR), coefficient of friction (COF), and surface roughness (Ra). Statistical analysis revealed that MWCNT content contributed up to 85.35% to wear reduction, with 0.5 wt% identified as the optimal reinforcement level, achieving the lowest WR (3.1 mm3/N·m) and Ra (0.7 µm). Complementary morphological characterization via SEM and AFM confirmed microstructural improvements at optimal loading and identified degradation features (ploughing, agglomeration) at 0 wt% and 0.75 wt%. Regression models (R2 > 0.95) effectively captured the nonlinear wear response, while a Random Forest model trained on GLCM-derived image features (e.g., correlation, entropy) yielded WR prediction accuracy of R2 ≈ 0.93. Key image-based predictors were found to correlate strongly with measured tribological metrics, validating the integration of surface texture analysis into predictive modeling. This integrated framework combining experimental design, mathematical modeling, and image-based machine learning offers a robust pathway for designing high-performance, sustainable nanocomposites with data-driven diagnostics for wear prediction. Full article
(This article belongs to the Special Issue Bio-Abio Nanocomposites)
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16 pages, 2895 KiB  
Article
Comparing a Whole Grain Blend with Polished White Rice for Starch Digestibility and Gut Microbiota Fermentation in Diabetic Patients: An In Vitro Study
by Qian Du, Ruisheng Fu, Ming Zhao and Meihong Xu
Foods 2025, 14(15), 2557; https://doi.org/10.3390/foods14152557 - 22 Jul 2025
Viewed by 347
Abstract
The high glycemic index (GI) of polished white rice (WR) presents challenges for blood glucose control in diabetes. This study investigated the in vitro digestibility of a whole grain blend (WGB, composed of black, red, and brown rice) and its effects on the [...] Read more.
The high glycemic index (GI) of polished white rice (WR) presents challenges for blood glucose control in diabetes. This study investigated the in vitro digestibility of a whole grain blend (WGB, composed of black, red, and brown rice) and its effects on the gut microbiota in elderly diabetic individuals. WGB exhibited lower starch digestibility (69.76 ± 5.71% vs. 73.02 ± 6.16%) and a reduced estimated glycemic index (eGI, 73.43 ± 4.49 vs. 77.55 ± 2.64) than WR, likely due to its higher amylose content. WGB fermentation increased Bifidobacterium and Lactobacillaceae, reduced pro-inflammatory Bacteroides fragilis and Enterocloster bolteae, and released more arabinose and xylose. Additionally, WGB yielded higher isobutyrate, while WR contained more glucose and fructose in its structure, leading to increased acetate production and a more acidic environment. Functional analysis revealed that WGB upregulated pathways related to fatty acid elongation and fiber fermentation. These findings suggest WGB as a viable staple food alternative for diabetic patients, offering dual benefits in glycemic control and gut microbiota. Full article
(This article belongs to the Section Food Nutrition)
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15 pages, 5045 KiB  
Article
Transpiration and Water Use Efficiency of Mediterranean Eucalyptus Genotypes Under Contrasting Irrigation Regimes
by Juan C. Valverde, Rafael A. Rubilar, Alex Medina, Matías Pincheira, Verónica Emhart, Yosselin Espinoza, Daniel Bozo and Otávio C. Campoe
Plants 2025, 14(14), 2232; https://doi.org/10.3390/plants14142232 - 19 Jul 2025
Viewed by 314
Abstract
Water scarcity is a key constraint for commercial Eucalyptus plantations, particularly given the increasing frequency of droughts driven by climate change. This study assessed annual transpiration (Tr) and water use efficiency (WUE) across eight genotypes subjected to contrasting irrigation regimes (WR). A split-plot [...] Read more.
Water scarcity is a key constraint for commercial Eucalyptus plantations, particularly given the increasing frequency of droughts driven by climate change. This study assessed annual transpiration (Tr) and water use efficiency (WUE) across eight genotypes subjected to contrasting irrigation regimes (WR). A split-plot design was implemented, comprising two irrigation levels: high (maintained above 75% of field capacity) and low (approximately 25% above the permanent wilting point). The genotypes included Eucalyptus globulus (EgH, EgL), E. nitens × globulus (EngH, EngL), E. nitens (En), E. camaldulensis × globulus (Ecg), E. badjensis (Eb), and E. smithii (Es). Between stand ages of 7 and 9 years (2020–2023), we measured current annual increment (CAI), leaf area index (LAI), Tr, and WUE. Under high WR, CAI ranged from 8 to 36 m3 ha−1 yr−1, Tr from 520 to 910 mm yr−1, and WUE from 0.7 to 2.9 kg m−3. Low irrigation reduced CAI by 5–25% and Tr by 10–35%, while WUE responses varied across genotypes, ranging from a 12% decrease to a 48% increase. Based on their functional responses, genotypes were grouped as follows: (i) stable performers (Es, Ecg, Eb) exhibited high WUE and consistent Tr under both WR; (ii) partially plastic genotypes (EgH, EngH) combined moderate reductions in Tr with improved WUE; and (iii) water-sensitive genotypes (EgL, EngL, En) showed substantial declines in Tr alongside variable WUE gains. These findings underscore the importance of selecting genotypes with adaptive water-use traits to improve the resilience and long-term sustainability of Eucalyptus plantations in Mediterranean environments. Full article
(This article belongs to the Section Plant Response to Abiotic Stress and Climate Change)
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27 pages, 4187 KiB  
Article
Assessing Occupational Work-Related Stress and Anxiety of Healthcare Staff During COVID-19 Using Fuzzy Natural Language-Based Association Rule Mining
by Abdulaziz S. Alkabaa, Osman Taylan, Hanan S. Alqabbaa and Bulent Guloglu
Healthcare 2025, 13(14), 1745; https://doi.org/10.3390/healthcare13141745 - 18 Jul 2025
Viewed by 249
Abstract
Background/Objective: Frontline healthcare staff who contend diseases and mitigate their transmission were repeatedly exposed to high-risk conditions during the COVID-19 pandemic. They were at risk of mental health issues, in particular, psychological stress, depression, anxiety, financial stress, and/or burnout. This study aimed to [...] Read more.
Background/Objective: Frontline healthcare staff who contend diseases and mitigate their transmission were repeatedly exposed to high-risk conditions during the COVID-19 pandemic. They were at risk of mental health issues, in particular, psychological stress, depression, anxiety, financial stress, and/or burnout. This study aimed to investigate and evaluate the occupational stress of medical doctors, nurses, pharmacists, physiotherapists, and other hospital support crew during the COVID-19 pandemic in Saudi Arabia. Methods: We collected both qualitative and quantitative data from a survey given to public and private hospitals using methods like correspondence analysis, cluster analysis, and structural equation models to investigate the work-related stress (WRS) and anxiety of the staff. Since health-related factors are unclear and uncertain, a fuzzy association rule mining (FARM) method was created to address these problems and find out the levels of work-related stress (WRS) and anxiety. The statistical results and K-means clustering method were used to find the best number of fuzzy rules and the level of fuzziness in clusters to create the FARM approach and to predict the work-related stress and anxiety of healthcare staff. This innovative approach allows for a more nuanced appraisal of the factors contributing to work-related stress and anxiety, ultimately enabling healthcare organizations to implement targeted interventions. By leveraging these insights, management can foster a healthier work environment that supports staff well-being and enhances overall productivity. This study also aimed to identify the relevant health factors that are the root causes of work-related stress and anxiety to facilitate better preparation and motivation of the staff for reorganizing resources and equipment. Results: The results and findings show that when the financial burden (FIN) of healthcare staff increased, WRS and anxiety increased. Similarly, a rise in psychological stress caused an increase in WRS and anxiety. The psychological impact (PCG) ratio and financial impact (FIN) were the most influential factors for the staff’s anxiety. The FARM results and findings revealed that improving the financial situation of healthcare staff alone was not sufficient during the COVID-19 pandemic. Conclusions: This study found that while the impact of PCG was significant, its combined effect with FIN was more influential on staff’s work-related stress and anxiety. This difference was due to the mutual effects of PCG and FIN on the staff’s motivation. The findings will help healthcare managers make decisions to reduce or eliminate the WRS and anxiety experienced by healthcare staff in the future. Full article
(This article belongs to the Special Issue Depression, Anxiety and Emotional Problems Among Healthcare Workers)
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25 pages, 3721 KiB  
Article
Phenotyping for Drought Tolerance in Different Wheat Genotypes Using Spectral and Fluorescence Sensors
by Guilherme Filgueiras Soares, Maria Lucrecia Gerosa Ramos, Luca Felisberto Pereira, Beat Keller, Onno Muller, Cristiane Andrea de Lima, Patricia Carvalho da Silva, Juaci Vitória Malaquias, Jorge Henrique Chagas and Walter Quadros Ribeiro Junior
Plants 2025, 14(14), 2216; https://doi.org/10.3390/plants14142216 - 17 Jul 2025
Viewed by 397
Abstract
The wheat planted at the end of the rainy season in the Cerrado suffers from a strong water deficit. A selection of genetic material with drought tolerance is necessary. In improvement programs that evaluate a large number of materials, efficient, automated, and non-destructive [...] Read more.
The wheat planted at the end of the rainy season in the Cerrado suffers from a strong water deficit. A selection of genetic material with drought tolerance is necessary. In improvement programs that evaluate a large number of materials, efficient, automated, and non-destructive phenotyping is essential, which requires the use of sensors. The experiment was conducted in 2016 using a phenotyping platform, where irrigation gradients ranging from 184 (WR4) to 601 mm (WR1) were created, allowing for the comparison of four genotypes. In addition to productivity, we evaluated plant height, hectoliter weight, the number of spikes per square meter, ear length, photosynthesis, and the indices calculated by the sensors. For most morphophysiological parameters, extreme stress makes it difficult to discriminate materials. WR1 (601 mm) and WR2 (501 mm) showed similar trends in almost all variables. The data validated the phenotyping platform, which creates an irrigation gradient, considering that the results obtained, in general, were proportional to the water levels. The similar trend between sensors (NDVI, PRI, and LIFT) and morphophysiological, plant growth, and crop yield evaluations validated the use of sensors as a tool in selecting drought-tolerant wheat genotypes using a non-invasive methodology. Considering that only four genotypes were used, none showed absolute and unequivocal tolerance to drought; however, each genotype exhibited some desirable characteristics related to drought tolerance mechanisms. Full article
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25 pages, 2721 KiB  
Article
GIS-Based Assessment of Stormwater Harvesting Potentials: A Sustainable Approach to Alleviate Water Scarcity in Rwanda’s Eastern Savanna Agroecological Zone
by Herve Christian Tuyishime and Kyung Sook Choi
Water 2025, 17(14), 2045; https://doi.org/10.3390/w17142045 - 8 Jul 2025
Viewed by 539
Abstract
Water scarcity remains critical in Rwanda’s Eastern Savanna Agroecological Zone due to erratic rainfall, prolonged dry seasons, and rising water demands. This challenge threatens agricultural productivity, food security, and livelihoods. Stormwater harvesting presents a sustainable solution that increases water availability and mitigates the [...] Read more.
Water scarcity remains critical in Rwanda’s Eastern Savanna Agroecological Zone due to erratic rainfall, prolonged dry seasons, and rising water demands. This challenge threatens agricultural productivity, food security, and livelihoods. Stormwater harvesting presents a sustainable solution that increases water availability and mitigates the impacts of climate variability. This study utilizes Geographic Information System (GIS) tools and SCS-CN to assess stormwater harvesting potential in the region. The methodology includes analyzing land use, soil type, rainfall data (30 years, from 1994 to 2023), and topography. Key research steps involve delineating catchment areas, estimating runoff volumes, and selecting optimal storage sites using multi-criteria decision analysis. Findings include eight main water reservoirs, each with a unique code (W_R1 to W_R8), geographic coordinates (X and Y), and 10 million cubic meters storage volumes. W_R1 has the smallest volume at 0.242 × 106 m3, while W_R2 has the largest volume at 8.51 × 106 m3. W_R3, W_R5, and W_R7 are additional noteworthy reservoirs with sizable capacities. The findings contribute to policy formulation and Sustainable Development Goals (SDGs) related to clean water, food security, and climate action. This research provides a replicable framework for addressing water scarcity and enhancing long-term resilience in water-stressed regions. Full article
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17 pages, 2905 KiB  
Article
Water Stress Is Differently Tolerated by Fusarium-Resistant and -Susceptible Chickpea Genotypes During Germination
by Ümmühan Kaşıkcı Şimşek, Murat Dikilitas, Talap Talapov and Canan Can
Life 2025, 15(7), 1050; https://doi.org/10.3390/life15071050 - 30 Jun 2025
Viewed by 277
Abstract
Chickpea is a legume that grows in most parts of the world. It is negatively affected by abiotic and biotic factors like drought and fungal diseases, respectively. One of the most important soil-borne pathogens affecting chickpeas is Fusarium oxysporum f.sp. ciceris (Foc [...] Read more.
Chickpea is a legume that grows in most parts of the world. It is negatively affected by abiotic and biotic factors like drought and fungal diseases, respectively. One of the most important soil-borne pathogens affecting chickpeas is Fusarium oxysporum f.sp. ciceris (Foc). Its population dynamics in the soil are affected by fluctuations in soil water content and host characteristics. For the last three decades, drought has been common in most areas of the world due to global warming. Drought stress decreases the quality and quantity of the chickpeas, particularly where soil-borne pathogens are the main stress factor for plants. The use of both drought-tolerant and disease-resistant cultivars may be the only option for cost-effective yield production. In this study, we screened the seeds of twelve chickpea genotypes WR-315, JG-62, C-104, JG-74, CPS-1, BG-212, ANNIGERI, CHAFFA, BG-215, UC-27, ILC-82, and K-850 for drought tolerance at increasing polyethylene glycol (PEG) concentrations (0-, 5-, 7.5-, 10-, 15-, 20-, 25-, 30- and 50%) to create drought stress conditions at different severities. The performances of genotypes that were previously tested in Foc resistance/susceptibility studies were assessed in terms of percentage of germination, radicle and hypocotyl length, germination energy, germination rate index, mean germination time, and vigor index in drought conditions. We determined the genotypes of C-104, CPS-1, and WR-315 as drought-susceptible, moderately drought-tolerant, and drought-tolerant, respectively. We then elucidated the stress levels of selected genotypes (20-day-old seedlings) at 0–15% PEG conditions via measuring proline and malondialdehyde (MDA) contents. Our findings showed that genotypes that were resistant to Foc also exhibited drought tolerance. The responses of chickpea genotypes infected with Foc under drought conditions are the next step to assess the combined stress on chickpea genotypes. Full article
(This article belongs to the Special Issue Physiological Responses of Plants Under Abiotic Stresses)
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12 pages, 479 KiB  
Article
Impact of Preoperative Food Addiction on Weight Loss and Weight Regain Three Years After Bariatric Surgery
by Fernando Guerrero-Pérez, Natalia Vega Rojas, Isabel Sánchez, Lucero Munguía, Susana Jiménez-Murcia, Cristina Artero, Lucía Sobrino, Claudio Lazzara, Rosa Monseny, Mónica Montserrat, Silvia Rodríguez, Fernando Fernández-Aranda and Nuria Vilarrasa
Nutrients 2025, 17(13), 2114; https://doi.org/10.3390/nu17132114 - 26 Jun 2025
Viewed by 697
Abstract
Background: Food addiction (FA) is prevalent among individuals with severe obesity and has been associated with poorer weight loss (WL) outcomes after dietary interventions. However, its long-term impact after bariatric surgery (BS) remains unclear. Objective: This study aimed to evaluate the [...] Read more.
Background: Food addiction (FA) is prevalent among individuals with severe obesity and has been associated with poorer weight loss (WL) outcomes after dietary interventions. However, its long-term impact after bariatric surgery (BS) remains unclear. Objective: This study aimed to evaluate the effect of preoperative FA on WL and weight regain (WR) three years after different BS techniques. Methods: An ambispective study was conducted in 165 patients undergoing BS (41.1% sleeve gastrectomy [SG], 13.3% Roux-en-Y gastric bypass [RYGB], and 45.6% hypoabsorptive procedures [HA]). FA was assessed preoperatively using the Yale Food Addiction Scale 2.0. WL outcomes were evaluated at 1 and 3 years postoperatively. Mixed-effects models were used to assess longitudinal changes, adjusted for baseline weight, sex, type 2 diabetes (T2D), and height. Results: FA was present in 17.6% of patients. At 3 years, total WL was lower in FA patients compared to those without FA (−27.1% vs. −31.0%; p = 0.023), driven by greater WR from nadir (+8.3% vs. +1.7%; p = 0.03). The effect was particularly pronounced after RYGB and HA, but not after SG. Nevertheless, a substantial proportion of FA patients (58%) were no longer classified as having obesity at 3 years. The presence of FA was not associated with insufficient WL or lower T2D remission rates. Mixed models confirmed a significant interaction between FA and time, indicating a trend toward reduced WL over time in FA patients. Conclusions: Preoperative FA was not associated with a reduced likelihood of achieving satisfactory WL following BS. Our data does not support the use of preoperative FA as a decisive factor in guiding the choice of BS type. Although FA was associated with increased WR over time, clinically meaningful WL was achieved in most patients. Long-term multidisciplinary follow-up remains essential in this subgroup. Full article
(This article belongs to the Section Nutrition and Obesity)
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16 pages, 3652 KiB  
Article
Performance and Mechanism of Polycarboxylate Superplasticizer in Red Mud Blended Cementitious Materials
by Lei Yang, Pengfei Wang, Shuqiong Luo, Yaxin Wang and Shengye Xu
Polymers 2025, 17(13), 1738; https://doi.org/10.3390/polym17131738 - 22 Jun 2025
Viewed by 546
Abstract
The utilization of red mud by blending it into cement paste is still facing poor workability issues due to the finer particle size and higher water absorption of red mud, which can be solved by the addition of polycarboxylate superplasticizer (PCE) to effectively [...] Read more.
The utilization of red mud by blending it into cement paste is still facing poor workability issues due to the finer particle size and higher water absorption of red mud, which can be solved by the addition of polycarboxylate superplasticizer (PCE) to effectively maintain the working performance. However, the specific mechanisms by which different topologies of PCEs, in terms of water-reducing (WR)- and slump-retaining (SR)-type PCEs, influence red mud blended cement paste require further clarification. This research investigates the effect of WR-PCE and SR-PCE on the rheological properties, mechanical properties, and microscopic morphology of red mud blended cement paste under different red mud contents. The results demonstrated that at saturated dosages of 0.5% WR-PCE and 0.75% SR-PCE, both types of PCEs improved paste fluidity and reduced plastic viscosity and shear stress. Moreover, the time-dependent fluidity loss rate of the SR-PCE-incorporated paste was lower to that of the WR-PCE-incorporated paste at 30 and 60 min. With 0% and 25% red mud contents, the compressive strengths at 1, 3, 7, and 28 days were higher for WR-PCE than for SR-PCE due to the enhanced hydration of C2S and C3S. Furthermore, hydration products in the WR-PCE-incorporated paste were more uniformly distributed compared to the SR-PCE-incorporated paste. However, a 50% red mud content negatively impacted paste strength, likely due to the high alkalinity destabilizing the PCE. This study aims to elucidate the mechanistic relationship between PCE topology and the improved performance of red mud blended cement paste. Full article
(This article belongs to the Special Issue Application of Polymers in Cementitious Materials)
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18 pages, 2478 KiB  
Article
Concurrent Physical Activity Protects Against C26 Adenocarcinoma Tumor-Mediated Cardiac and Skeletal Muscle Dysfunction and Wasting in Males
by Louisa Tichy, Kimberly F. Allred, Erika T. Rezeli, Michael F. Coleman, Clinton D. Allred, Stephen D. Hursting and Traci L. Parry
Cells 2025, 14(12), 924; https://doi.org/10.3390/cells14120924 - 18 Jun 2025
Viewed by 382
Abstract
Muscle loss unresponsive to nutritional supplementation affects up to 80% of cancer patients and severely reduces survival and treatment response. Exercise may help preserve muscle mass and function, yet the translatability of preclinical methods remains questionable. This study aimed to assess how voluntary [...] Read more.
Muscle loss unresponsive to nutritional supplementation affects up to 80% of cancer patients and severely reduces survival and treatment response. Exercise may help preserve muscle mass and function, yet the translatability of preclinical methods remains questionable. This study aimed to assess how voluntary wheel running, a clinically relevant physical activity, protects skeletal and cardiac muscle against cancer-mediated dysfunction and identify underlying molecular mechanisms. Methods: BALB/c mice were assigned to sedentary nontumor-bearing (SED+NT), sedentary tumor-bearing (SED+T), wheel run nontumor-bearing (WR+NT), and wheel run tumor-bearing (WR+T). Tumor-bearing groups received 5 × 105 C26 cells; WR mice had wheel access for 4 weeks. Muscle function and tissue were analyzed for protective mechanisms. Results: SED+T mice exhibited significant fat and lean mass loss, indicating cachexia, which was prevented in WR+T mice. SED+T also showed 15% reduced grip strength and cardiac dysfunction, while WR+T preserved function. WR+T mice had lower expression of muscle wasting markers (Atrogin1, MuRF1, GDF15, GDF8/11). Physical activity also reduced tumor mass by 57% and volume by 37%. Conclusion: Voluntary wheel running confers tumor-suppressive, myoprotective, and cardioprotective effects. These findings support physical activity as a non-pharmacological strategy to combat cancer-related muscle wasting and dysfunction. Full article
(This article belongs to the Special Issue Emerging Topics in Cachexia)
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21 pages, 554 KiB  
Article
Exploring the Nexus Between a Supportive Workplace Environment, Employee Engagement, and Employee Performance in the Kingdom of Saudi Arabia
by Samma Faiz Rasool, Hana Mohelska, Fazal Ur Rehman, Hamid Raza and Muhammad Zaheer Asghar
Adm. Sci. 2025, 15(6), 230; https://doi.org/10.3390/admsci15060230 - 16 Jun 2025
Viewed by 945
Abstract
Grounded in motivation theory, this study examines the direct relationship between a supportive workplace environment (SWE) and employee performance (EP). The SWE has been identified into three dimensions, i.e., work recognition (WR), work motivation (WM), and career development (CD). Moreover, we focused on [...] Read more.
Grounded in motivation theory, this study examines the direct relationship between a supportive workplace environment (SWE) and employee performance (EP). The SWE has been identified into three dimensions, i.e., work recognition (WR), work motivation (WM), and career development (CD). Moreover, we focused on the mediating effect of employee engagement (EE) on the relationship between SWE and EP. A quantitative research method was used, and data were collected through a questionnaire survey. Data were collected from 349 respondents. The target population were the senior managers, middle managers, and administrative staff working in the semi-government organizations based in Riyadh, Saudi Arabia. The data were analyzed using partial least squares structural equation modeling (PLS-SEM) software version 4.0. The results indicate that in the direct relationship, workplace recognition, workplace motivation, and career development are positively connected with EP. Similarly, the findings show that employee engagement positively mediates between an SWE (work recognition, work motivation, and career development) and EP. This study suggests that managers can establish practices acknowledging and appreciating employee contributions, leading to increased motivation and improved performance. Creating a work environment that fosters work motivation by addressing employees’ physical and safety, social, and egoistic needs can further enhance employee engagement and performance. The study highlights the significant role of work recognition, work motivation, career development, and employee engagement in influencing employee performance. This study also recommends some practical implications for the semi-governmental organizations. First, it was suggested that organizations create a workplace environment in which employees feel appreciated, valued, and happy. Second, the organizations introduce the employee engagement culture at the department level as well as at the organizational level. Third, the organizations also introduce flexible work schedules for middle-level and administrative staff. Finally, Saudi organizations recognize the output of their employees and provide them with monetary incentives. Full article
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28 pages, 68627 KiB  
Article
TBM Enclosure Rock Grade Prediction Method Based on Multi-Source Feature Fusion
by Yong Huang, Xiewen Hu, Shilong Pang, Wei Fu, Shuaipeng Chang, Bin Gao and Weihua Hua
Appl. Sci. 2025, 15(12), 6684; https://doi.org/10.3390/app15126684 - 13 Jun 2025
Viewed by 436
Abstract
Aiming to mitigate engineering risks such as tunnel face collapse and equipment jamming caused by poor geological conditions during the construction of tunnel boring machines (TBMs), this study proposes a TBM surrounding rock grade prediction method based on multi-source feature fusion. Firstly, a [...] Read more.
Aiming to mitigate engineering risks such as tunnel face collapse and equipment jamming caused by poor geological conditions during the construction of tunnel boring machines (TBMs), this study proposes a TBM surrounding rock grade prediction method based on multi-source feature fusion. Firstly, a multi-source dataset is established by systematically integrating TBM tunnelling parameters, horizontal acoustic profile (HSP) detection data and three-dimensional geological spatial information. In the data preprocessing stage, the TBM data is cleaned and divided according to the mileage section, the statistical characteristics of key tunnelling parameters (thrust, torque, penetration, etc.) are extracted, and the rock fragmentation index (TPI, FPI, WR) is fused to construct a composite feature vector. The Direct-LiNGAM causal discovery algorithm is innovatively introduced to analyse the nonlinear correlation mechanism between multi-source features, and then a hybrid model, TRNet, which combines the local feature extraction ability of convolutional neural networks and the nonlinear approximation advantages of Kolmogorov–Arnold networks, is constructed. Verified by a real tunnel project in western Sichuan, China, the prediction accuracy of TRNet for surrounding rock grade on the test set reaches an average of 92.15%, which is higher than other data-driven methods. The results show that the prediction method proposed in this paper can effectively predict the surrounding rock grade of the tunnel face during TBM tunnelling, and provide decision support for the dynamic regulation of tunnelling parameters. Full article
(This article belongs to the Special Issue Tunnel and Underground Engineering: Recent Advances and Challenges)
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10 pages, 240 KiB  
Article
Does the Use of Oral Nutritional Supplements Influence the Rate of Postoperative Complications After Uniportal Video-Assisted Thoracoscopic Lung Resection?
by Marco Andolfi, Michela Tiberi, Michele Salati, Marina Taus, Nadia Campelli, Francesco Xiumè, Alberto Roncon, Gian Marco Guiducci, Anna Chiara Nanto, Claudia Cola, Loris Angeli Temperoni and Majed Refai
J. Clin. Med. 2025, 14(12), 4226; https://doi.org/10.3390/jcm14124226 - 13 Jun 2025
Viewed by 380
Abstract
Background: The positive effects of oral nutritional supplements (ONS) on postoperative outcomes have been well recognized in several previous studies. However, to date, little data has been available with respect to determining the best immune modulating supplement to use and what its impact [...] Read more.
Background: The positive effects of oral nutritional supplements (ONS) on postoperative outcomes have been well recognized in several previous studies. However, to date, little data has been available with respect to determining the best immune modulating supplement to use and what its impact might be in thoracic surgery. The aim of this study was to evaluate the role of preoperative immune-nutritional supplement intake as predictor of postoperative cardiopulmonary complications (CPCs) in patients undergoing uniportal video-assisted thoracoscopic (uVATS) lung resection. Methods: This is a retrospective, observational study enrolling consecutive patients who underwent uVATS lung resections for cancer from January 2022 to December 2024 in the context of the Enhanced Pathway of Care (EPC) Program. All patients were evaluated by a nutritionist and dietetics team during the preoperative phase. The nutritional protocol consisted of 250 mL ONS rich in arginine, omega-3-fatty acids, and nucleotides to be taken twice a day for 5–7 days before surgery. Results: Four hundred ninety-one patients were enrolled: 277 patients underwent anatomic lung resection and 214 underwent wedge resection (WR). Utilizing the univariate analysis, we found that in patients undergoing anatomic lung resection, not-ONS-intake, high Body Mass Index (BMI), and arrythmia were correlated with a higher CPCs rate compared to the patients without nutritional supplementation (7.2% ONS vs. 15% not-ONS, p = 0.04; BMI 28.4 kg/m2 vs. BMI 26.4 kg/m2, p = 0.03; 31.2% arrythmia vs. 9.4% no-arrythmia, p < 0.01). These correlations, except for BMI, were confirmed after stepwise logistic regression. Alternately, in patients undergoing WR, hypertension and low-FEV1% were associated with a higher CPCs rate (5.1% hypertension vs. 0.4% no-hypertension, p = 0.02; FEV1% 79.7% vs. 95%, p = 0.01). Conclusions: Our results demonstrated that preoperative ONS after uVATS anatomic lung resection, in the context of an EPC program, influences the postoperative period, reducing the CPCs rate. Full article
(This article belongs to the Special Issue Thoracic Surgery: State of the Art and Future Directions)
14 pages, 558 KiB  
Article
External Validation and Extension of a Cochlear Implant Performance Prediction Model: Analysis of the Oldenburg Cohort
by Rieke Ollermann, Robert Böscke, John Neidhardt and Andreas Radeloff
Audiol. Res. 2025, 15(3), 69; https://doi.org/10.3390/audiolres15030069 - 12 Jun 2025
Viewed by 347
Abstract
Background/Objectives: Rehabilitation success with a cochlear implant (CI) varies considerably and identifying predictive factors for the reliable prediction of speech understanding with CI remains a challenge. Hoppe and colleagues have recently described a predictive model, which was specifically based on Cochlear™ recipients [...] Read more.
Background/Objectives: Rehabilitation success with a cochlear implant (CI) varies considerably and identifying predictive factors for the reliable prediction of speech understanding with CI remains a challenge. Hoppe and colleagues have recently described a predictive model, which was specifically based on Cochlear™ recipients with a four-frequency pure tone average (4FPTA) ≤ 80 dB HL. The aim of this retrospective study is to test the applicability to an independent patient cohort with extended inclusion criteria. Methods: The Hoppe et al. model was applied to CI recipients with varying degrees of hearing loss. Model performance was analyzed for Cochlear™ recipients with 4FPTA ≤ 80 dB HL and for all recipients regardless of 4FPTA. Subgroup analyses were conducted by WRSmax and CI manufacturer. Results: The model yielded comparable results in our patient cohort when the original inclusion criteria were met (n = 24). Extending the model to patients with profound hearing loss (4FPTA > 80 dB HL; n = 238) resulted in a weaker but significant correlation (r = 0.273; p < 0.0001) between predicted and measured word recognition score at 65 dB with CI (WRS65(CI)). Also, a higher percentage of data points deviated by more than 20 pp, either better or worse. When patients provided with CIs from different manufacturers were enrolled, the prediction error was also higher than in the original cohort. In Cochlear™ recipients with a maximum word recognition score (WRSmax) > 0% (n = 83), we found a moderate correlation between measured and predicted scores (r = 0.3274; p = 0.0025). Conclusions: In conclusion, as long as the same inclusion criteria are used, the Hoppe et al. (2021) prediction model results in similar prediction success in our cohort, and thus seems applicable independently of the cohort used. Nevertheless, it has limitations when applied to a broader and more diverse patient cohort. Our data suggest that the model would benefit from adaptations for broader clinical use, as the model lacks sufficient sensitivity in identifying poor performers. Full article
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