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17 pages, 4550 KiB  
Article
Spatiotemporal Characteristics and Associated Circulation Features of Summer Extreme Precipitation in the Yellow River Basin
by Degui Yao, Xiaohui Wang and Jinyu Wang
Atmosphere 2025, 16(7), 892; https://doi.org/10.3390/atmos16070892 - 21 Jul 2025
Viewed by 175
Abstract
By utilizing daily precipitation data from 400 meteorological stations in the Yellow River Basin (YRB) of China, atmospheric and oceanic reanalysis data, this study investigates the climatological characteristics, leading modes, and relationships with atmospheric circulation and sea surface temperature (SST) of summer extreme [...] Read more.
By utilizing daily precipitation data from 400 meteorological stations in the Yellow River Basin (YRB) of China, atmospheric and oceanic reanalysis data, this study investigates the climatological characteristics, leading modes, and relationships with atmospheric circulation and sea surface temperature (SST) of summer extreme precipitation in the YRB from 1981 to 2020 through the extreme precipitation metrics and Empirical Orthogonal Function (EOF) analysis. The results indicate that both the frequency and intensity of extreme precipitation exhibit an eastward and southward increasing pattern in terms of climate state, with regions of higher precipitation showing greater interannual variability. When precipitation in the YRB exhibits a spatially coherent enhancement pattern, high latitudes exhibits an Eurasian teleconnection wave train that facilitates the southward movement of cold air. Concurrently, the northward extension of the Western Pacific subtropical high (WPSH) enhances moisture transport from low latitudes to the YRB, against the backdrop of a transitioning SST pattern from El Niño to La Niña. When precipitation in the YRB shows a “south-increase, north-decrease” dipole pattern, the southward-shifted Ural high and westward-extended WPSH converge cold air and moist in the southern YRB region, with no dominant SST drivers identified. Full article
(This article belongs to the Section Meteorology)
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16 pages, 3471 KiB  
Article
Reconstruction of Pleistocene Evolutionary History of the Root Vole Alexandromys oeconomus (Cricetidae, Rodentia) in Northern Asia
by Tatyana V. Petrova, Andrey A. Lissovsky, Semyon Yu. Bodrov, Aivar V. Kuular, Nikolay I. Putintsev, Munkhtsog Bariushaa and Natalia I. Abramson
Diversity 2025, 17(7), 497; https://doi.org/10.3390/d17070497 - 20 Jul 2025
Viewed by 239
Abstract
Previous phylogeographic study of the root vole (Alexandromys oeconomus) revealed four mitochondrial cytochrome b lineages—North and Central European, North (=Central) Asian and Beringian. Three of them were studied in detail, while the North Asian lineage, which occupies the most extensive territory [...] Read more.
Previous phylogeographic study of the root vole (Alexandromys oeconomus) revealed four mitochondrial cytochrome b lineages—North and Central European, North (=Central) Asian and Beringian. Three of them were studied in detail, while the North Asian lineage, which occupies the most extensive territory and is considered to be the place of origin for the species, was understudied. In the framework of the current study, we obtained 95 new sequences (34 localities) from the wide territory of Northern Asia and in total, examined 940 specimens from 181 localities throughout the species’ distribution range. The North Asian lineage was found to be more diverse than the Beringian and the European lineages. Southern Siberia and especially the Altai–Sayan region displayed the highest haplotype and nucleotide diversity, suggesting the region’s role as a genetic diversity hotspot. We suppose that the expansion of the North Asian lineage started from Western Transbaikalia. Its representatives colonised the territory from the Urals to the northern shore of the Okhotsk Sea, and then spread in the opposite direction, to Southern Siberia. As a result, a mixture of haplogroups is observed in the Altai–Sayan region. According to the BEAST analysis calibrated with the first A. oeconomus records, the MRCA of North Asian and Beringian lineages is dated back to ~0.82 Mya, and the first divergence within the North Asian lineage may have occurred ~0.6 Mya. When compared with colonisation times of other representatives of the Arvicolinae subfamily, our dating seems to be overestimated. In this regard, molecular data for dated fossil remains of the root vole are essential for subsequent studies. Full article
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26 pages, 1859 KiB  
Article
Domestication of Source Text in Literary Translation Prevails over Foreignization
by Emilio Matricciani
Analytics 2025, 4(3), 17; https://doi.org/10.3390/analytics4030017 - 20 Jun 2025
Viewed by 845
Abstract
Domestication is a translation theory in which the source text (to be translated) is matched to the foreign reader by erasing its original linguistic and cultural difference. This match aims at making the target text (translated text) more fluent. On the contrary, foreignization [...] Read more.
Domestication is a translation theory in which the source text (to be translated) is matched to the foreign reader by erasing its original linguistic and cultural difference. This match aims at making the target text (translated text) more fluent. On the contrary, foreignization is a translation theory in which the foreign reader is matched to the source text. This paper mathematically explores the degree of domestication/foreignization in current translation practice of texts written in alphabetical languages. A geometrical representation of texts, based on linear combinations of deep–language parameters, allows us (a) to calculate a domestication index which measures how much domestication is applied to the source text and (b) to distinguish language families. An expansion index measures the relative spread around mean values. This paper reports statistics and results on translations of (a) Greek New Testament books in Latin and in 35 modern languages, belonging to diverse language families; and (b) English novels in Western languages. English and French, although attributed to different language families, mathematically almost coincide. The requirement of making the target text more fluent makes domestication, with varying degrees, universally adopted, so that a blind comparison of the same linguistic parameters of a text and its translation hardly indicates that they refer to each other. Full article
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18 pages, 3113 KiB  
Article
Chemical Composition of Wolframite from the Porokhovskoe and Yugo-Konevskoe W Deposits (Central Urals): Implications for Fluid Evolution and Ore Genesis
by Konstantin Novoselov, Danil Rogov and Dmitry A. Artemyev
Minerals 2025, 15(6), 661; https://doi.org/10.3390/min15060661 - 19 Jun 2025
Viewed by 295
Abstract
The composition of wolframite from ores of the Porokhovskoe and Yugo-Konevskoe W greisen deposits in the Central Urals is studied using SEM-EDS and LA-ICP-MS analyses. The Porokhovskoe deposit is localized in a metamorphosed volcanosedimentary sequence of Lower Silurian age, and the Yugo-Konevskoe is [...] Read more.
The composition of wolframite from ores of the Porokhovskoe and Yugo-Konevskoe W greisen deposits in the Central Urals is studied using SEM-EDS and LA-ICP-MS analyses. The Porokhovskoe deposit is localized in a metamorphosed volcanosedimentary sequence of Lower Silurian age, and the Yugo-Konevskoe is enclosed in an eponymous granite pluton of Middle Permian–Lower Triassic age. Most studied wolframite grains belong to hűbnerite. The Fe/(Fe + Mn) value of wolframite varies in a range of 0.02–0.50. Wolframite from both deposits is enriched in Zn, Nb, and Mg. The wolframite from the Porokhovskoe deposit is enriched in V, Sc, Zn, and Mg and is depleted in Mo, U, rare earth elements (REEs), Nb, and Ta, compared to wolframite from the Yugo-Konevskoe deposit. It is suggested that this difference is due to the occurrence of ore veins in different rocks at different distance from the source of the ore-forming fluid, which cools down as it moves away from the source, leading to a decrease in the incorporation of trace elements by the lower-temperature wolframite. The predominance of heavy REEs over light REEs in all the studied wolframite is explained by the close ionic radii of heavy REEs to the main mineral-forming elements Fe and Mn. Full article
(This article belongs to the Section Mineral Geochemistry and Geochronology)
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17 pages, 3781 KiB  
Article
Railway and Road Infrastructure in Saiga Antelope Range in Kazakhstan
by Nazerke Bizhanova, Alexey Grachev, Nurkuisa Rametov, Yerlik Baidavletov, Saltore Saparbayev, Maxim Bespalov, Sergey Bespalov, Indira Kumayeva, Yerzhan Toishibekov, Anna Khamchukova and Yuri Grachev
Diversity 2025, 17(6), 431; https://doi.org/10.3390/d17060431 - 19 Jun 2025
Viewed by 1111
Abstract
The saiga antelope (Saiga tatarica), a keystone migratory species of the Central Asian steppes and deserts, is increasingly threatened by habitat fragmentation due to the rapidly expanding transport infrastructure in Kazakhstan, which hosts approximately 95% of the species’ global population. This [...] Read more.
The saiga antelope (Saiga tatarica), a keystone migratory species of the Central Asian steppes and deserts, is increasingly threatened by habitat fragmentation due to the rapidly expanding transport infrastructure in Kazakhstan, which hosts approximately 95% of the species’ global population. This study provides a spatial assessment of railway and road infrastructure across the contemporary ranges of the Betpaqdala, Ustyurt, and Ural saiga populations. Using the literature and our field data from the 1980s to the present day, combined with geographic information system (GIS)-based analysis of 80,427 km of roads and 4021 km of railways, we have quantified infrastructure densities and identified critical barriers to saiga migration using kernel density and minimum convex polygons (MCP) estimations. The results reveal a negative connection between infrastructure density and occurrences of saiga herds, particularly in the Ustyurt population, where a high railway density coincides with severely reduced migratory activity and a reduction in this population’s winter range by 79.84% since 2015. Major railways such as Sekseuildi–Zhezqazgan, Zhezqazgan–Zharyk, and Shalqar–Beineu intersect essential migratory pathways and have contributed to significant range contraction, subpopulation isolation, and northward shifts in seasonal habitats. In contrast, the Ural population (subject to minimal railway infrastructure interference) has shown robust demographic recovery. While roads are more widespread, their impact is less severe due to greater permeability. However, upcoming projects such as the China–Europe transit corridor and the “Center–West” regional development corridor could amplify future threats. We recommend immediately implementing wildlife-friendly infrastructure, including overpasses and ecological corridors, to preserve the connectivity of saiga ranges and support the long-term conservation of this ungulate species. Full article
(This article belongs to the Section Biodiversity Conservation)
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17 pages, 1593 KiB  
Review
Conservation of Apis mellifera mellifera L. in the Middle Ural: A Review of Genetic Diversity, Ecological Adaptation, and Breeding Perspectives
by Olga Frunze, Alexander V. Petukhov, Anna Z. Brandorf, Mikhail K. Simankov, Hyunjee Kim and Hyung-Wook Kwon
Insects 2025, 16(5), 512; https://doi.org/10.3390/insects16050512 - 11 May 2025
Viewed by 752
Abstract
The European dark bee is well adapted to cold winters and short summers. However, threats from habitat loss, pests, and hybridization with southern bees pose significant challenges to its populations. The Perm region (Middle Ural, Russia) hosts a distinct population of Apis mellifera [...] Read more.
The European dark bee is well adapted to cold winters and short summers. However, threats from habitat loss, pests, and hybridization with southern bees pose significant challenges to its populations. The Perm region (Middle Ural, Russia) hosts a distinct population of Apis mellifera mellifera, known as Prikamskaya. Despite extensive local research, a comprehensive analysis remains lacking. This review presents an analysis based on selected historical, ecological, genetic, and regulatory sources relevant to honey bee populations in northern climates. Inclusion criteria prioritized peer-reviewed scientific literature, regional monographs, institutional reports, and expert contributions published from the 20th century onward. Preference was given to studies addressing environmental conditions, queen-rearing practices, population structure, and conservation strategies. At the northern limit of honey bee distribution, the region has diverse forest zones and a growing season of 145–190 days, influencing nectar availability from lime, honeysuckle, and willow. Although the region’s potential honey yield is estimated at 390,919,300 kg, only 6.7% of its 3,007,200 colonies are commercially utilized, largely due to the low number of apiaries specializing in local honey bees. Distinct northern and southern types of A. m. mellifera have been identified based on morphological (cubital index) and physiological (cold resistance) traits, although links to genetic diversity remain underexplored. This study underscores the importance of regional conservation efforts in preserving the genetic diversity of A. m. mellifera, emphasizing the need for targeted breeding strategies to address climate change and hybridization, ensuring the sustainability of agriculture and natural ecosystems worldwide Full article
(This article belongs to the Section Social Insects and Apiculture)
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33 pages, 44898 KiB  
Article
The Supra-Salt Sedimentary Sequence of the North Caspian Depression: Stratigraphy and Sedimentary History
by Aitbek Akhmetzhanov, Saule Uvakova, Kenzhebek Ibrashev, Gauhar Akhmetzhanova and Vyacheslav Zhemchuzhnikov
Geosciences 2025, 15(4), 143; https://doi.org/10.3390/geosciences15040143 - 9 Apr 2025
Viewed by 602
Abstract
The North Caspian Basin, known for its oil and gas potential, was formed because of the evolution of the ancient Tethys Ocean and is also a result of the collision of the East European, Kazakhstania, and Siberian paleocontinents. At the beginning of the [...] Read more.
The North Caspian Basin, known for its oil and gas potential, was formed because of the evolution of the ancient Tethys Ocean and is also a result of the collision of the East European, Kazakhstania, and Siberian paleocontinents. At the beginning of the Mesozoic Era, it was a part of the northern continental margin of the Neo-Tethys, which formed Eurasia. In the Late Triassic and Early Jurassic, a major restructuring of the North Caspian sedimentary basin occurred, characterized by angular unconformity and the erosion of underlying sediments in the coastal zones of the basin. The sedimentary succession of the depression accumulating in the Mesozoic Era consisted of alternating siliciclastic and carbonate rocks. It began to form due to the destruction of the uplifts formed north and west of the East European craton and Urals, which resulted in coastal clastic material in the Triassic and Jurassic, but by the end of the Jurassic and Cretaceous, when all uplifts existing in the north of Tethys were leveled, it was mostly marine environments that contributed to the accumulation of siliciclastic and carbonate strata. The appearance of a large amount of sedimentary material towards the center of the depression, causing stress, as well as the deflection of the basement, contributed to fault tectonics and the resumption and manifestation of salt tectonics. As a result of the continuous diapirism of salt bodies during the Late Mesozoic, mini basins were formed, in which different sedimentogenesis was manifested. These processes contributed to the redistribution of hydrocarbons from the underlying pre-salt formations to the intermediate depth interval post-salt succession with Permian–Triassic and also near-surface Jurassic–Cretaceous formations. Full article
(This article belongs to the Section Sedimentology, Stratigraphy and Palaeontology)
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15 pages, 2372 KiB  
Article
Microbiome of the Soil and Rhizosphere of the Halophyte Spergularia marina (L.) Griseb in the Saline Sites of Lake Kurgi, the South Urals: Metagenomic Analysis
by Anastasia S. Tugbaeva, Alexander A. Ermoshin, Gregory I. Shiryaev and Irina S. Kiseleva
Microbiol. Res. 2025, 16(3), 64; https://doi.org/10.3390/microbiolres16030064 - 10 Mar 2025
Viewed by 1072
Abstract
The study of the metagenomes of bacterial communities in saline areas is relevant in connection with the global salinization of agricultural lands. The aim of this study was to investigate the biodiversity and structure of rhizobacterial communities associated with the halophyte S. marina [...] Read more.
The study of the metagenomes of bacterial communities in saline areas is relevant in connection with the global salinization of agricultural lands. The aim of this study was to investigate the biodiversity and structure of rhizobacterial communities associated with the halophyte S. marina from low and moderate sulfate–chloride salinity habitats. The bacterial community of bulk and rhizosphere soil was analyzed using high-throughput sequencing of the V1–V9 region of 16S rRNA by Oxford Nanopore Technologies. Alpha and beta diversity indices were calculated. A total of 55 phyla and 309 genera of bacteria were identified, among which Proteobacteria and Bacteroidetes dominated. The occurrence of Planctomycetes, Verrucomicrobia, and Acidobacteria in the rhizosphere was higher than in the bulk soil. Bacterial alpha diversity in the bulk soil decreased with increasing salinity, while it increased in the rhizosphere. The proportion of the halotolerant bacteria of Flavobacterium and Alteromonas genera significantly grew with increasing salinity both in the bulk and rhizosphere soil. In addition, in the rhizosphere, the percentage of Comamonas, Methylibium, Lysobacter, Planctomyces, Sphingomonas, Stenotrophomonas, and Lewinella genera increased. Among them, several genera included plant growth promoting rhizobacteria (PGPR). In the more saline bulk soil, the proportion of halotolerant genera Bacillus, Salinimicrobium, Marinobacter, Clostridium, Euzebya, KSA1, Marinobacter, Clostridium, Salinimicrobium, and Halorhodospira was also higher compared to the low saline site. Thus, increasing the salinity changed the taxonomic structure of the bacterial communities of both bulk soil and rhizosphere. Full article
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11 pages, 961 KiB  
Review
The Ural Owl as a Keystone Species in Interspecific Interactions Among Avian Predators—A Review
by Łukasz Kajtoch
Diversity 2025, 17(2), 109; https://doi.org/10.3390/d17020109 - 1 Feb 2025
Cited by 1 | Viewed by 1312
Abstract
Ural owls are one of the largest owls in Europe, exhibiting known aggressive behaviour toward other raptors. They are known to interact with nearly all sympatric owls and many diurnal raptors. To summarise these interactions, a literature search was undertaken in the Web [...] Read more.
Ural owls are one of the largest owls in Europe, exhibiting known aggressive behaviour toward other raptors. They are known to interact with nearly all sympatric owls and many diurnal raptors. To summarise these interactions, a literature search was undertaken in the Web of Sciences and Scopus databases using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses methodology as well principal books on owl biology. The search revealed 22 relevant publications that (along with the book data) described the Ural owl’s relations with seven owls and six diurnal raptor species. The Ural owl is subordinate only to the largest predators like golden eagles and eagles, although only its chicks are known to be killed. Contrary to that, the Ural owls shape the distribution of numerous other species, mostly by strong competition (e.g., forcing tawny owls to breed in suboptimal habitats) or by predation (killing smaller owls and diurnal raptors). Their occurrence could be also protective for some species like boreal owls thanks to the removal of intermediate predators. The relations of Ural owls with goshawks are interesting, which seem to live in some balance—temporal avoidance of activity with frequent co-occurrence. Thanks to their association with old-growth forests and their impact on other predators in their territories, Ural owls act as keystone species in mountainous and boreal forests in Europe. Considering this ecosystem service, Ural owls should be effectively protected e.g., by designing forest-management-free zones around their nesting sites. Full article
(This article belongs to the Special Issue Birds in Temperate and Tropical Forests—2nd Edition)
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19 pages, 3764 KiB  
Article
Dynamics of Annual Cone Crops of Siberian Fir (Abies sibirica Ledeb.) in Conifer Forests of Pre-Ural Region (Russia) Based on 47 Years of Observations
by Alexandr Davydychev and Gleb Zaitsev
Forests 2025, 16(2), 234; https://doi.org/10.3390/f16020234 - 25 Jan 2025
Viewed by 1219
Abstract
Because seed reproduction is the sole means of reproduction available for coniferous tree species, it plays a crucial role in determining the species’ ecological adaptability and the competitiveness of species under specific biocoenosis conditions. Therefore, the primary goal of studying the periodicity and [...] Read more.
Because seed reproduction is the sole means of reproduction available for coniferous tree species, it plays a crucial role in determining the species’ ecological adaptability and the competitiveness of species under specific biocoenosis conditions. Therefore, the primary goal of studying the periodicity and cyclical production of cones (seeds) is to forecast the peaks and recessions of natural renewal in various forest ecosystems. The crop dynamics of Siberian fir (Abies sibirica Ledeb.) cones in three mature natural conifer forests in the broad-leaf coniferous forest subzone of the pre-Ural region (Russia) was analysed based on long-term observations spanning 47 years. The conifer forests investigated had a considerable deficit of cones (seeds) for natural renewal under the forest canopy. High cone crops occur every 10 years or twice a decade under most favourable conditions. However, cone production has no distinct periodicity, and it is impossible to forecast a high crop of cones based only on long-term data. The levels of fir crop cones were clearly correlated with climate factors. Late winter climate in previous (weak and moderate positive correlation) and current years (weak and moderate negative correlation) affected the fir cone crop. High and even average fir cone crops occur spontaneously with no discernible pattern. In coniferous forests, cone crops are highest on slopes with high insolation levels and on sustainably wet soils. Full article
(This article belongs to the Special Issue Forest Monitoring and Modeling Under Climate Change)
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21 pages, 5919 KiB  
Article
A Computationally Efficient Method for the Diagnosis of Defects in Rolling Bearings Based on Linear Predictive Coding
by Mohammad Mohammad, Olga Ibryaeva, Vladimir Sinitsin and Victoria Eremeeva
Algorithms 2025, 18(2), 58; https://doi.org/10.3390/a18020058 - 21 Jan 2025
Cited by 1 | Viewed by 898
Abstract
Monitoring the condition of rolling bearings is a crucial task in many industries. An efficient tool for diagnosing bearing defects is necessary since they can lead to complete machine failure and significant economic losses. Traditional diagnosis solutions often rely on a complex artificial [...] Read more.
Monitoring the condition of rolling bearings is a crucial task in many industries. An efficient tool for diagnosing bearing defects is necessary since they can lead to complete machine failure and significant economic losses. Traditional diagnosis solutions often rely on a complex artificial feature extraction process that is time-consuming, computationally expensive, and too complex to deploy in practice. In actual working conditions, however, the amount of labeled fault data available is relatively small, so a deep learning model with good generalization and high accuracy is difficult to train. This paper proposes a solution that uses a simple feedforward artificial neural network (NN) for classification and adopts the linear predictive coding (LPC) algorithm for feature extraction. The LPC algorithm finds several coefficients for a given signal segment containing information about the signal spectrum, which is sufficient for further classification. The LPC-NN solution was tested on the Case Western Reserve University (CWRU) and South Ural State University (SUSU) datasets. The results demonstrated that, in most cases, LPC-NN yielded an accuracy of 100%. The proposed method achieves higher diagnostic accuracy and stability to load changes than other advanced techniques, has a significantly improved time performance, and is conducive to real-time industrial fault diagnosis. Full article
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27 pages, 6768 KiB  
Article
Complex Study of Settlements Dating from the Paleolithic to Medieval Period in the Ural Mountains on the Border of Europe and Asia
by Valentina Prikhodko, Nikita Savelev, Vyacheslav Kotov, Sergey Nikolaev, Evgeny Ruslanov, Mikhail Rumyantsev and Elena Manakhova
Geosciences 2025, 15(1), 31; https://doi.org/10.3390/geosciences15010031 - 16 Jan 2025
Cited by 1 | Viewed by 1100
Abstract
Soil, geochemical, microbiological, and archeological studies were conducted at eight settlements dating from the Paleolithic to Late Medieval and Modern Ages near the southern Trans-Urals Mountains, Russia. The forest-steppe landscapes, rivers, and abundant mineral resources have attracted people to the region since ancient [...] Read more.
Soil, geochemical, microbiological, and archeological studies were conducted at eight settlements dating from the Paleolithic to Late Medieval and Modern Ages near the southern Trans-Urals Mountains, Russia. The forest-steppe landscapes, rivers, and abundant mineral resources have attracted people to the region since ancient times. Cultural layers (CLs) are marked by finds of ceramics fragments, animal bones, stone, and metal tools. The properties of CLs include close-to-neutral pH, being well structured, the absence of salinity, enrichment with exchangeable calcium, and anthropogenic phosphorus (0.2–0.4%). The majority of CLs start at a depth of 3–25 cm, extend to 40–60 cm, and contain 6–10% organic carbon (Corg) in the 0–20 cm layer, reflecting carbon input from modern-day processes. At the Ishkulovo site (0.6–0.8 ka BP), Corg decreases to 1.3% because the CL is below 80 cm, and in the absence of fresh organic material input, carbon has been mineralized. The proximity of sites to deposits of copper, chromium, zinc, and manganese in the Ural Mountains creates natural high-content anomalies in the region, as indicated by their abundance in soils and parent rocks. In the past, these elements were also released into CLs from metal products, ceramic fragments, and raw materials used in their manufacture. The sites are quite far (18–60 km) from the Magnitogorsk Metallurgical plant, but industrial stockpiles of S (technogenic coefficient—Ct 30–87%), and, less often, Cr, Mn, and Sr (Ct 30–40%) accumulated in surface layers. These three factors have led to the concentration of pollutants of the first (arsenic, chromium, lead, and zinc) and second (cobalt, copper, and nickel) hazard classes at CLs, often in quantities 2–5 times higher than values for parent materials and geosphere average content (“Clarke” value), and, and less often, more than the allowable content for human health. This may have influenced their health and behavioral functions. Due to the above properties, chernozems have a high buffering capacity and a strong bond with heavy metals. Therefore, no inhibition of microbes was observed. The microbial biomass of the 0–10 cm layer is high, 520–680 µg C/g, and microbes cause the emission of 1.0 C-CO2 µg/g of soil per hour. During the ancient settlements’ development, a favorable paleoclimate was noted based on the data cited. This contributed to the spread of productive paleolandscapes, ensuring the development of domestic cattle breeding and agriculture. Full article
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12 pages, 368 KiB  
Communication
Evaluation of Polygenic Risk Score for Prediction of Childhood Onset and Severity of Asthma
by Olga Savelieva, Alexandra Karunas, Inga Prokopenko, Zhanna Balkhiyarova, Irina Gilyazova, Irina Khidiyatova and Elza Khusnutdinova
Int. J. Mol. Sci. 2025, 26(1), 103; https://doi.org/10.3390/ijms26010103 - 26 Dec 2024
Viewed by 1130
Abstract
Asthma is a common complex disease with susceptibility defined through an interplay of genetic and environmental factors. Responsiveness to asthma treatment varies between individuals and is largely determined by genetic variability. The polygenic score (PGS) approach enables an individual risk of asthma and [...] Read more.
Asthma is a common complex disease with susceptibility defined through an interplay of genetic and environmental factors. Responsiveness to asthma treatment varies between individuals and is largely determined by genetic variability. The polygenic score (PGS) approach enables an individual risk of asthma and respective response to drug therapy. PGS models could help to predict the individual risk of asthma using 26 SNPs of drug pathway genes involved in the metabolism of glucocorticosteroids (GCS), and beta-2-agonists, antihistamines, and antileukotriene drugs associated with the response to asthma treatment within GWAS were built. For PGS, summary statistics from the Trans-National Asthma Genetic Consortium GWAS meta-analysis, and genotype data for 882 individuals with asthma/controls from the Volga-Ural region, were used. The study group was comprised of Russian, Tatar, Bashkir, and mixed ethnicity individuals with asthma (N = 378) aged 2–18 years. and individuals without features of atopic disease (N = 504) aged 4–67 years from the Volga-Ural region. The DNA samples for the study were collected from 2000 to 2021. The drug pathway genes’ PGS revealed a higher odds for childhood asthma risk (p = 2.41 × 10−12). The receiver operating characteristic (ROC) analysis showed an Area Under the Curve, AUC = 0.63. The AUC of average significance for moderate-to-severe and severe asthma was observed (p = 5.7 × 10−9, AUC = 0.64). Asthma drug response pathway gene variant PGS models may contribute to the development of modern approaches to optimise asthma diagnostics and treatment. Full article
(This article belongs to the Special Issue Molecular Advances and Perspectives of Lung Disease: 2nd Edition)
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18 pages, 4134 KiB  
Article
Applying Data Analysis and Machine Learning Methods to Predict Permafrost Coast Erosion
by Daria Bogatova and Stanislav Ogorodov
Geosciences 2025, 15(1), 2; https://doi.org/10.3390/geosciences15010002 - 26 Dec 2024
Viewed by 1071
Abstract
This study aims to establish a scientific and methodological basis for predicting shoreline positions using modern data analysis and machine learning techniques. The focus area is a 5 km section of the Ural coast along Baydaratskaya Bay in the Kara Sea. This region [...] Read more.
This study aims to establish a scientific and methodological basis for predicting shoreline positions using modern data analysis and machine learning techniques. The focus area is a 5 km section of the Ural coast along Baydaratskaya Bay in the Kara Sea. This region was selected due to its diverse geomorphological features, varied lithological composition, and significant presence of permafrost processes, all contributing to complex patterns of shoreline change. Applying advanced data analysis methods, including correlation and factor analysis, enables the identification of natural signs that highlight areas of active coastal retreat. These insights are valuable in arctic development planning, as they help to recognize zones at the highest risk of significant shoreline transformation. The erosion process can be conceptualized as comprising two primary components to construct a predictive model for coastal retreat. The first is a random variable that encapsulates the effects of local structural changes in the coastline alongside fluctuations due to climatic conditions. This component can be statistically characterized to define a confidence interval for natural variability. The second component represents a systematic shift, which reflects regular changes in average shoreline positions over time. This systematic component is more suited to predictive modeling. Thus, modern information processing methods allow us to move from descriptive to numerical assessments of the dynamics of coastal processes. The goal is ultimately to support responsible and sustainable development in the highly sensitive arctic region. Full article
(This article belongs to the Section Cryosphere)
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43 pages, 42509 KiB  
Review
Gold and Platinum Group Element Occurrence Related to Black Shale Formations in the Southern Urals (Russia): A Review
by Alexander V. Snachev and Mikhail A. Rassomakhin
Minerals 2024, 14(12), 1283; https://doi.org/10.3390/min14121283 - 17 Dec 2024
Cited by 1 | Viewed by 1760
Abstract
This paper gives a brief description of all structural–formational zones in the Southern Urals. Riphean and Paleozoic black shale sediments with strong positive anomalies of gold and a number of other elements are widely developed within this region. This paper reports that carbonaceous [...] Read more.
This paper gives a brief description of all structural–formational zones in the Southern Urals. Riphean and Paleozoic black shale sediments with strong positive anomalies of gold and a number of other elements are widely developed within this region. This paper reports that carbonaceous shales are a very favorable geochemical environment for the primary accumulation of many industrially important elements. Under certain conditions (in the areas of magmatism, zonal metamorphism, and tectonic activity), they can serve as a source of metals and concentrate deposits, and occurrences of gold, silver, and platinoids. Among these deposits, a new type of vein-embedded gold–sulfide mineralization with dispersed gold and platinum metals, localized in rocks rich in organic carbon, has been detected. In this study, we made an attempt to summarize and systematize research materials on this issue. The presented data indicate a high potential of carbonaceous sediments in the Southern Urals, providing a good basis for further prospecting works and analytical studies. Full article
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