269 Results Found

A recessive Short Tandem Repeat expansion in RFC1 has been found to be associated with cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS), and to be a frequent cause of late onset ataxia and sensory neuropathy. The usual procedu...

During cell division, genome integrity is maintained by faithful DNA replication during S phase, followed by accurate segregation in mitosis. Many DNA metabolic events linked with DNA replication are also regulated throughout the cell cycle. In eukar...

A common polymorphism (c.80A>G) in the gene coding for the reduced folate carrier (SLC19A1, commonly known as RFC-1) has been associated with maternal risk of the birth of a child with Down Syndrome (DS), but results are controversial. We searched...

Plastid ribosome biogenesis is important for plant growth and development. REGULATOR OF FATTY ACID COMPOSITION3 (RFC3) is a member of the bacterial ribosomal protein S6 family and is important for lateral root development. rfc3-2 dramatically reduces...

Endotoxin (lipopolysaccharide) testing of drugs is routinely required in pharmaceutical industries. Suitable compendial assays are defined by national pharmacopoeias. At this time, Limulus Amoebocyte Lysate (LAL) assays are the gold standard. LAL is...

Replication Factor C Subunit 4 (RFC4), an oncogene implicated in many human cancers, has yet to be extensively studied in many cancer types to determine its expression patterns and tumor tissue function. Various bioinformatics tools were used to anal...

Autism Spectrum Disorder (ASD) is a group of neurodevelopmental disorders with complex genetic etiology. Recent studies have indicated that children with ASD may have altered folate or methionine metabolism, suggesting that the folate–methionine cycl...

Proliferating cell nuclear antigen (PCNA) is a DNA clamp that functions in key roles for DNA replication and repair. After the completion of DNA synthesis, PCNA should be unloaded from DNA in a timely way. The ATAD5-RFC-Like Complex (ATAD5-RLC) unloa...

Deep learning and Machine Learning Algorithms has become the most popular method for analyzing and extracting features especially in medical images. And feature extraction has made this task much easier. Our aim is to check which feature extraction t...

The main hallmarks of cancer include sustaining proliferative signaling and resisting cell death. We analyzed the genes of the WNT pathway and seven cross-linked pathways that may explain the differences in aggressiveness among cancer types. We divid...

This paper presents the first application of ethnobotanical studies to screen for allelopathic species among medicinal plants for sustainable weed management. This study assesses the possible relationship between ethnobotanical indices and allelopath...

Raman flow cytometry (RFC) uniquely integrates the “label-free” capability of Raman spectroscopy with the “high-throughput” attribute of traditional flow cytometry (FCM), offering exceptional performance in cell characterizati...

Traditional Time-Stamping Authorities provide reliable temporal evidence. However, they operate as single points of trust and do not supply a tamper-evident record of event ordering. This paper presents a standards-compliant extension that anchors ea...

Chromium pollution has emerged as a critical environmental concern, prompting extensive research into the chemical and mineralogical properties of refined ferrochrome (RFC) slag, the leaching of chromium using sulfuric acid, and the adsorption of chr...

This paper presents a method for predicting atmospheric duct conditions from a clutter power spectrum using deep learning. To accurately predict the duct conditions, deep learning with a binary classification is applied to the proposed refractivity f...

The relationship between sleep posture and sleep quality has been studied comprehensively. Over 70% of chronic diseases are highly correlated with sleep problems. However, sleep posture monitoring requires professional devices and trained nursing sta...

Heart disease is a danger to people’s health because of its prevalence and high mortality risk. Predicting cardiac disease early using a few simple physical indications collected from a routine physical examination has become difficult. Clinica...

Background: In the United States, chronic obstructive pulmonary disease (COPD) is a significant cause of mortality. As far as we know, it is a chronic, inflammatory lung condition that cuts off airflow to the lungs. Many symptoms have been reported f...

Gram-negative bacterial endotoxins can cause pathophysiological effects such as high fever when introduced into the bloodstream. Therefore, endotoxin testing is necessary when producing injectable pharmaceuticals. The pharmaceutical industry has wide...

During each cell duplication, the entirety of the genomic DNA in every cell must be accurately and quickly copied. Given the short time available for the chore, the requirement of many proteins, and the daunting amount of DNA present, DNA replication...

A bias current in the power system will cause saturation of the measuring current transformer (CT), leading to an increase in measurement error. Therefore, in this paper, we first conducted measurements of the direct current component in a 10 kV dist...

Various genomic variants were linked to inherited peripheral neuropathies (IPNs), including large duplication/deletion and repeat expansion, making genetic diagnosis challenging. This large case series aimed to identify the genetic characteristics of...

Replication factor C (RFC) is a heteropentameric ATPase associated with the diverse cellular activities (AAA+ATPase) protein complex, which is composed of one large subunit, known as RFC1, and four small subunits, RFC2/3/4/5. Among them, RFC1 and RFC...

Sustainable management of orchard fields requires detailed information about the tree types, which is a main component of precision agriculture programs. To this end, hyperspectral imagery can play a major role in orchard tree species mapping. Effici...

With the increasing number of end users that are using multimedia services, demand for access network high-bitrate systems with sufficient quality of services is also increasing. However, this might not always be ensured by telecom operators, as they...

Glioblastoma (GBM) is one of the deadliest of all human cancers. Developing therapies targeting GBM cancer stem cells or glioma stem cells (GSCs), which are deemed responsible for the malignancy of GBM due to their therapy resistance and tumor-initia...

Botanical surveys in all parts of Pakistan are mainly focused on ethnomedicinal uses of plants, and very little attention has been paid to documenting edible wild fruit species (EWFs). Multiple methodologies and tools were used for data collection. I...

Accurate detection of microbial contamination is essential in the assessment of toxicological and immunological responses to various materials, as low-level contaminants can lead to confounding results. Traditional endotoxin testing relies on the Lim...

The health and welfare of livestock are significant for ensuring the sustainability and profitability of the agricultural industry. Addressing efficient ways to monitor and report the health status of individual cows is critical to prevent outbreaks...

(1) Background: Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is characterized by late-onset cerebellar ataxia, bilateral vestibulopathy, and sensory neuronopathy mostly due to biallelic RFC1 expansion. (2) Objectives:...

The paper proposes a model based on receptive field enhancement and cross-scale fusion (RFCS-YOLO). It addresses challenges like complex backgrounds and problems of missing and mis-detecting traffic targets in bad weather. First, an efficient feature...

The intersection through which two fundamental processes meet provides a unique vantage point from which to view cellular regulation. On the one hand, DNA replication is at the heart of cell division, generating duplicate chromosomes that allow each...

The Trentino-South Tyrol region is a special statute region of northeastern Italy. This territory is of particular interest for its morphology, flourishing vegetation, and history, having been a meeting area among different civilizations. Hence, Tren...

The emergence of the Internet of Things (IoT) has made wireless connectivity ubiquitous and necessary. Extending the IoT to the Industrial Internet of Things (IIoT) places significant demands in terms of reliability on wireless connectivity. The Inst...

This systematic literature review aims to understand new developments and challenges in facial recognition technology. This will provide an understanding of the system principles, performance metrics, and applications of facial recognition technology...

Experimental economic laboratories run many studies to test theoretical predictions with actual human behaviour, including public goods games. With this experiment, participants in a group have the option to invest money in a public account or to kee...

In order to comprehensively evaluate the properties of rock-filled concrete (RFC) with the strength of C15, lab experimental test and in-situ test are applied to explore the mechanical, hydraulic, ultrasonic characteristics of RFC in Hantang reservoi...

Immune checkpoint inhibitors (ICIs) became one of the most revolutionary cancer treatments, especially in melanoma. While they have been proven to prolong survival with lesser side effects compared to chemotherapy, the accurate prediction of response...

Rock-filled concrete (RFC) technology is a new type of mass concrete construction technology, which consists of two basic components: the force transfer frame formed by large-size rock accumulation and the matrix formed by self-compacting concrete (S...

A rock-filled concrete (RFC) dam is an original dam construction technology invented in China nearly 20 years ago. The technology has been continuously improved and innovated upon, and the accumulated rich practical experience gradually formed a comp...

In the preparation of ready-mixed concrete, it is inevitable to produce waste fresh concrete (WFC). An efficient, low-cost and environmentally friendly recycling scheme is the key to WFC recycling. In this work, we directly added some unhardened WFC...

A low-grade copper ore from an Australian mine was processed under continuous steady state conditions using the REFLUX^™ Flotation Cell (RFC^™), and the performance was quantified with reference to a batch mechanical cell and the plant circ...

The TROPOMI XCH₄ data product requires rigorous cloud filtering to achieve a product accuracy of <1%. To this end, operational XCH₄ data processing has been based on SUOMI-NPP VIIRS cloud observations. However, SUOMI-NPP is nearing the end of its...

Foam concrete (FC) serves as an efficient construction material that combines well thermal insulation and structural properties. The studies of material characteristics, including the mechanical, physical, rheological, and functional properties of li...

Rock-filled concrete (RFC) is an advanced construction material that integrates high-performance self-compacting concrete (HSCC) with large rocks exceeding 300 mm, providing advantages such as reduced hydration heat and increased construction process...

Rock-filled concrete (RFC) has good performance in terms of energy savings, cost reduction, and CO₂ emissions as a novel massive concrete construction technology. There have been studies into replacing natural rocks in RFC with large blocks of solid...

Occupational enrichment (OE) is directed at introducing variations in the tank water so that fish can exercise as they do in the wild. Two trials were carried out to test the effects of randomly fired underwater currents (RFC) on rainbow trout (Oncor...

Due to a rapid increase in accessible Earth observation data coupled with high computing and storage capabilities, multiple efforts over the past few years have aimed to map land use/land cover using image time series with promising outcomes. Here, w...

Traditional rice production is often reliant on the unsustainable practice of utilizing intensive inputs in monoculture cropping systems. Alternatives fallow cover cropping and rice–fish coculture (RFC) offer promising solutions. However, the p...

Superficial discolored spots on Atlantic salmon (Salmo salar) fillets are a serious quality problem for commercial seafood farming. Previous reports have proposed that the black spots (called melanized focal changes (MFCs)) may be melanin, but no con...