Search Results (58)

This study investigated the nuanced influence of urban morphology on the thermal performance of nine mass housing blocks (21–26, 28–30) in New Belgrade’s Central Zone. These blocks, showcasing diverse structures, provided a robust basis for evaluating the design parameters. ENVI-met simulations were used to assess two scenarios: an “asphalt-only” environment, isolating the urban structure’s impact, and a “real-world” scenario, including green infrastructure (GI). Overall, the findings emphasize that while GI offers mitigation, the inherent urban built structure fundamentally determines thermal outcomes. An urban block’s thermal performance, it turns out, is a complex interplay between morphological factors and local climate. Crucially, simple metrics like Green Area Percentage (GAP) and Building Coverage Ratio (BCR) proved unreliable predictors of thermal performance. This highlights the critical need for urban planning regulations to evolve beyond basic surface indicators and embrace sophisticated, context-sensitive design principles for effective heat mitigation. Optimal performance arises from morphologies that actively manage heat accumulation and facilitate its dissipation, a characteristic exemplified by Block 22’s integrated design. However, even the best-performing Block 22 remains warmer compared to denser central areas, suggesting that urban densification can be a strategy for heat mitigation. Given New Belgrade’s blocks are protected heritage, targeted GI reinforcements remain the only viable approach for improving the outdoor thermal comfort. Full article

This paper examines two large urban projects within a defined theoretical and methodological framework. Firstly, we analyse how the city administration in Belgrade, in post-socialist Serbia, managed the initial steps of the transformation of a part of the old town into the new large-scale development, the Belgrade Waterfront (BW), on the right bank of the Sava River. The contested outcome of the land transformation process contributes to a recognition of the unethical decision-making and performance of the responsible city authorities. Secondly, the postwar planning and construction of New Belgrade, in particular its Central Zone, is critically examined from the aspect of radical urban landscape transformation and its impact on society. Through a critical examination of the spatial development of the socialist period, we aim to identify emancipatory architectural and urban practises that could be an alternative to contemporary spatial production and that might provide a notion of key strategies for (re)establishing corresponding forms of socio-spatial justice. The two aforementioned research subjects are examined using different research questions, methodological tools, and different theoretical frameworks, which overlap, merge, and combine in the part of the study where the obtained results are discussed. Full article

Small green spaces are the most common type of greenery in cities, but very little is known about their impact on thermal comfort. It has been established that larger green spaces (large city parks, urban forests, etc.) have a significant effect on the formation of thermal comfort in cities. Conversely, it has been shown that this effect is highly variable in smaller green spaces (particularly those <3 ha). This study investigated the impact of smaller green spaces (<3 ha) of various categories (parks, squares, and street tree lines) on the thermal comfort of urban open spaces. In total, 18 green spaces in Belgrade were selected, where specialised meteorological measurements were conducted during summer and winter, and the PET index and UTCI were calculated using the RayMan Pro (Version 3.1 Beta) software. Research has shown that green spaces ranging from 0.9 to 3 ha have an average difference of 4.04 °C in the PET index and 3.27 °C in the UTCI. For areas between 0.3 and 0.9 ha, the differences are 2.32 °C for PET and 2.05 °C for UTCI, while for spaces <0.3 ha, the differences are 2.19 °C for PET and 2.12 °C for UTCI. In all cases, the values of the PET index and UTCI were higher in green spaces compared to areas without greenery, with differences ranging from 2.19 to 4.04 °C for PET and 2.05–3.27 °C for UTCI. It was determined that green spaces <3 ha increased the PET index by an average of 2.75 °C and the UTCI by 2.41 °C. The results of this study showed that despite their size, small green areas can significantly improve thermal comfort. This study highlights the importance of these green spaces and provides a basis for the planning of new or renovated existing urban green spaces to mitigate the effects of climate change in cities. Full article

This study focused on the investigation of soil samples from the alluvial zone of the Sava River, located near the heating plant in New Belgrade, Serbia. Using gas chromatography with flame ionization detection (GC-FID), a broad range of alkanes, including linear n-alkanes (C₁₀ to C₃₃) and isoprenoids, was analyzed in all samples. The obtained datasets were effectively made simpler by applying multivariate statistical analysis. Various geochemical indices (CPI, ACL, AI, TAR, etc.) and ratios (S/L, Paq, Pwax, etc.) were calculated and used to distinguish between biogenic and anthropogenic contributions. This approach added a higher level of precision to the source identification of hydrocarbons and provided a detailed geochemical characterization of the investigated soil. The results showed that the topsoil had a high content of TPH (average value, 90.65 mg kg⁻¹), potentially related to an accidental oil spill that occurred repeatedly over extended periods. The uncommon n-alkane profiles reported for the investigated soil samples are probably the result of inputs related to anthropogenic sources, emphasizing that petroleum was the main source of the short-chain n-alkanes. The methodology developed in this study was proven to be efficient for the assessment of the environmental quality of the soil in an urban part of New Belgrade, but it can also be a useful tool for soil monitoring and for a pollution assessment in other (sub)urban areas. Full article

Marburg virus (MARV), a filovirus, was first identified in 1967 in Marburg, Germany, and Belgrade, former Yugoslavia. Since then, MARV has caused sporadic outbreaks of human disease with high case fatality rates in parts of Africa, with the largest outbreak occurring in 2004/05 in Angola. From 2021 to 2023, MARV outbreaks occurred in Guinea, Ghana, New Guinea, and Tanzania, emphasizing the expansion of its endemic area into new geographical regions. There are currently no approved vaccines or therapeutics targeting MARV, but several vaccine candidates have shown promise in preclinical studies. We compared three vaccine platforms simultaneously by vaccinating hamsters with either a single dose of an adenovirus-based (ChAdOx-1 MARV) vaccine, an alphavirus replicon-based RNA (LION-MARV) vaccine, or a recombinant vesicular stomatitis virus-based (VSV-MARV) vaccine, all expressing the MARV glycoprotein as the antigen. Lethal challenge with hamster-adapted MARV 4 weeks after vaccination resulted in uniform protection of the VSV-MARV and LION-MARV groups and 83% of the ChAdOx-1 MARV group. Assessment of the antigen-specific humoral response and its functionality revealed vaccine-platform-dependent differences, particularly in the Fc effector functions. Full article

In this text, we discuss the “Beyond Quantum Music” project, which inspired pianists, composers, researchers, and innovators Sonja Lončar and Andrija Pavlović (LP Duo) to go beyond the boundaries of classical and avant-garde practices to create a new style in composition and performance on two unique DUALITY hybrid pianos that they invented and developed to create a new stage design for multimedia concert performances and establish a new musical genre as a platform for future musical expression. “Beyond Quantum Music” is a continuation of the groundbreaking art and science project “Quantum Music”, which began in 2015; we envisioned it as a long-term project. In order to build an experimental dialogue between music and quantum physics, we created the DUALITY Portable Hybrid Piano System. This innovative instrument was essential for expanding the current sound of the classical piano. As a result, new compositions and new piano sounds were produced using various synthesizers and sound samples derived from scientific experiments. The key place for this dialogue between music and science was the Delft University of Technology, the Netherlands, where Andrija Pavlović, as a Kavli artist in residence, and Sonja Lončar, as an expert, spent several months in 2022 collaborating with scientists to compose new music. Later on, we collaborated with the visual artist “Incredible Bob” to develop the idea for the multimedia concert “LP Duo plays Beyond Quantum Music” to be performed at various locations, including the Scientific Institute MedILS Split (Croatia), the Theater Hall JDP Belgrade (Serbia), the Congress Hall TU Delft (the Netherlands), and open-air concerts at the Kaleidoskop Festival (Novi Sad, Serbia) and Ars Electronica Festival in Linz (Austria). Full article

This study addressed problems related to the protection, reconstruction, and revitalisation of modern heritage, particularly the regeneration of mass housing estates built after WWII and facing the contemporary perils of urban decay and deterioration. It presented interdisciplinary research investigating the possibility of extending and complementing the heritage assessment methodology and broadening the scope of the criteria by including mass housing landscape values. Starting with a close reading of the key theoretical positions embedded in the conceptualisation and construction of New Belgrade, we investigated a set of holistic and time-based criteria, followed by contemporary methodologies for landscape quality assessment. The investigation was based on an urban landscape approach to heritage assessment and focuses on the Central Zone of New Belgrade, declared a heritage site in 2021. The interaction of the theoretical underpinnings of modern architecture and urban planning with urban landscape discourse, coupled with historically and theoretically relevant knowledge and data, resulted in an investigation of landscape-based criteria for further mass housing assessment. Finally, we presented the findings of the landscape quality assessment of the transformations of the Central Zone. This perspective could be used to extend the possibilities of this approach in order to (1) tackle the “thickness” of temporality related to (urban) landscapes; (2) rethink and redefine the applied heritage assessment approach; (3) open the assessment procedure to a wider range of stakeholders, particularly nonexperts and the local community; and (4) re-actualise the position and role of experts in the sense of communicating knowledge in a completely new context. Full article

The industrial heritage of the city of Belgrade is the focus of this research, which highlights the possibilities of preserving industrial heritage from the perspective of a contemporary context and sustainable development. Guided by theoretical principles on the preservation of cultural and industrial heritage, their values, authenticity and spirit of place, as well as the idea of the necessity of integrating industrial heritage into the contemporary context, this paper aims to examine the possibilities for the preservation of industrial heritage following theoretically established principles, with the introduction of new uses and sustainable solutions. The analysis of the case studies of Belgrade’s industrial heritage presented in this paper results from research conducted by the teachers, associates and students of the University of Belgrade, Faculty of Architecture. The research focuses on the possibilities of translating the principles of preserving cultural and industrial heritage from their theoretical definition to practical application. The students’ conceptual solutions for protection, revitalisation and presentation of the analysed case studies represent the research results. An important aspect of this paper is defining the criteria for valorising students’ conceptual solutions, which are aligned with the principles of preserving cultural heritage and establishing sustainable development. The valorisation of students’ conceptual solutions through a defined set of criteria indicates real possibilities for the simultaneous preservation of all the values of industrial heritage and its transformation into a social, ecological and economic resource of the contemporary city. Full article

This article provides a summary of the 9th International Congress of the International Society for Pathophysiology (ISP 2023) which took place in Belgrade, Serbia, from 4 to 6 July 2023. It describes the main trends and the most promising areas of research in current pathophysiology, including investigations of new pathogenic pathways, and the identification of cellular and molecular mechanisms, target molecules, genetic mechanisms, and new therapeutic strategies. The present article also highlights the research conducted by leading scientific teams and national pathophysiological societies from various countries that adds to our understanding of the pathogenesis of diseases and pathological processes. Full article

Resilient cities have emerged as novel urban ecosystems that respond to the increasing challenges of contemporary urban development. A new methodological approach is needed to measure and assess the degree of resilience of the urban landscape during the ongoing planning process, considering different planning and design scenarios. Based on this consideration, the first attempt of this study was to develop a resilience index that summarizes the application of resilience theory in urban landscape planning. Is geodesign an appropriate tool to assess urban resilience? This was the main research question and the topic of the workshop ’’IGC—Resilient City of Belgrade’’ at the Faculty of Forestry, University of Belgrade (Master Landscape Studio). The main result of this research is a model for urban resilience assessment with IGC geodesign, which allows to measure scenario changes through developed resilience indicators (index), which are determined by a set of parameters (area, redundancy, diversity, porosity, carbon sequestration, edge type, edge length, etc.). The methodological approach allows quantifying the impact of adopted innovations in geodesign scenario proposals, which plays a crucial role in strengthening the connection between landscape planning and design. In the context of the novel urban ecosystem, future urban landscape planning should focus on resilience as a measure to achieve sustainable development goals, supported by geodesign as a collaborative and spatially explicit negotiation tool. Full article

Although the frequency of myocarditis in the general population is very difficult to accurately determine due to the large number of asymptomatic cases, the incidence of this disease is increasing significantly due to better defined criteria for diagnosis and the development of modern diagnostic methods. The multitude of different etiological factors, the diversity of the clinical picture, and the variability of the diagnostic findings make this disease often demanding both for the selection of the diagnostic modality and for the proper therapeutic approach. The previously known most common viral etiology of this disease is today overshadowed by new findings based on immune-mediated processes, associated with diseases that in their natural course can lead to myocardial involvement, as well as the iatrogenic cause of myocarditis, which is due to use of immune checkpoint inhibitors in the treatment of cancer patients. Suspecting that a patient with polymorphic and non-specific clinical signs and symptoms, such as changes in ECG and echocardiography readings, has myocarditis is the starting point in the diagnostic algorithm. Cardio magnetic resonance imaging is non-invasive and is the gold standard for diagnosis and clinical follow-up of these patients. Endomyocardial biopsy as an invasive method is the diagnostic choice in life-threatening cases with suspicion of fulminant myocarditis where the diagnosis has not yet established or there is no adequate response to the applied therapeutic regimen. The treatment of myocarditis is increasingly demanding and includes conservative methods of treating heart failure, immunomodulatory and immunospressive therapy, methods of mechanical circulatory support, and heart transplantation. The goal of developing new diagnostic and therapeutic methods is to reduce mortality from this complex disease, which is still high. Full article

Introduction: Risk stratification in patients with COVID-19 is a challenging task. Early warning scores (EWSs) are commonly used tools in the initial assessment of critical patients. However, their utility in patients with COVID-19 is still undetermined. Aim: This study aimed to discover the most valuable predictive model among existing EWSs for ICU admissions and mortality in COVID-19 patients. Materials and methods: This was a single-center cohort study that included 3608 COVID-19 patients admitted to the University Clinical Hospital Center Bezanijska Kosa, Belgrade, Serbia, between 23 June 2020, and 14 April 2021. Various demographic, laboratory, and clinical data were collected to calculate several EWSs and determine their efficacy. For all 3608 patients, five EWSs were calculated (MEWS, NEWS, NEWS2, REMS, and qSOFA). Model discrimination performance was tested using sensitivity, specificity, and positive and negative predictive values. C statistic, representing the area under the receiver operating characteristic (ROC) curve, was used for the overall assessment of the predictive model. Results: Among the evaluated prediction scores for 3068 patients with COVID-19, REMS demonstrated the highest diagnostic performance with the sensitivity, PPV, specificity, and NPV of 72.1%, 20.6%, 74.9%, and 96.8%, respectively. In the multivariate logistic regression analysis, aside from REMS, age (p < 0.001), higher CT score (p < 0.001), higher values of urea (p < 0.001), and the presence of bacterial superinfection (p < 0.001) were significant predictors of mortality. Conclusions: Among all evaluated EWSs to predict mortality and ICU admission in COVID-19 patients, the REMS score demonstrated the highest efficacy. Full article

Hantaviridae currently encompasses seven genera and 53 species. Multiple hantaviruses such as Hantaan virus, Seoul virus, Dobrava-Belgrade virus, Puumala virus, Andes virus, and Sin Nombre virus are highly pathogenic to humans. They cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome or hantavirus pulmonary syndrome (HCPS/HPS) in many countries. Some hantaviruses infect wild or domestic animals without causing severe symptoms. Rodents, shrews, and bats are reservoirs of various mammalian hantaviruses. Recent years have witnessed significant advancements in the study of hantaviruses including genomics, taxonomy, evolution, replication, transmission, pathogenicity, control, and patient treatment. Additionally, new hantaviruses infecting bats, rodents, shrews, amphibians, and fish have been identified. This review compiles these advancements to aid researchers and the public in better recognizing this zoonotic virus family with global public health significance. Full article

The focus of this study is buildings for public purposes, specifically for higher education, planned in zones of spatial cultural-historical units. Sustainable urban planning in areas with cultural-historical heritage is a particular challenge since the higher education facilities themselves have their own functional requirements, which are much easier to fulfill in “softer” locations. The research objective is to prove the hypothesis that it is possible to indicate a prescription for the practical application of the theoretical model and define the necessary steps to achieve the best sustainable quality results in practice. The paper analyses the associated process, relational settings, circumstances, participants, and timelines, and it presents the results of final designs based on two parallel case studies of new capital buildings for the University of Belgrade. Methodologically it gives an overview of the context, referring to other research and examples, detailing chosen case studies, and describing their backgrounds, conditions and requirements, frameworks, chronologies, approaches, and results. The discussion concludes with theoretical models originating from the comparison of implemented steps in the process of creation and evaluation of architectural ideas and summarized similarities and differences, aiming that there is a common model suitable for further applications. The practical result of the research is findings about the pathway for the best original planning solution emphasized through the institution of urban architectural competitions as a mandatory step, recommending wider participation of experts in the process of evaluation. Full article

(1) Background: Education for sustainable development emphasizes the need to train future teachers to apply effective approaches to ensure the implementation of the Sustainable Development Goals defined by the 2030 Agenda. (2) Methods: The research aim was to determine empirical data to introduce an outdoor science teaching approach with peer tutoring to teacher candidates through its impact on their performance, i.e., achievement, perceived mental effort, and opinion on the applied approach. The applied approach represents the integration of physics and geography through the elective course homeland geography at the Faculty of Teacher Education in Belgrade. Students performed outdoor measurements of physical quantities in created tasks. The tasks aimed to engage students’ spatial thinking and critical observation skills, whereas the use of verbal skills and content presentation skills was encouraged through peer tutoring. (3) Results: The research results showed a positive impact of an outdoor science teaching approach with peer tutoring on students’ achievement. Additionally, we found that perceived mental effort decreases with the use of this approach. Lower mental effort indicated more space in working memory, which can be used for processing new information. Therefore, obtained results indicated that the applied teaching approach is suitable for students. (4) Conclusions: The obtained results should incentivize other faculties that train future teachers to apply an outdoor teaching approach with peer tutoring. As a result of preparing future teachers in a way that promotes awareness of sustainable development and the local environment, it can be expected that young people will be more interested in solving these important issues because they will see them in their environment and be connected to them. Full article