Search Results (16)

Because of local climate, a phenomenon called huaico occurs in the coastal regions of Peru, configured by an alluvial flow of surface runoff caused by precipitation and accompanied by the transport of solid particles. A total of 24% of the huaicos recorded in Peru from 2003 to 2019 were concentrated in the Department of Lima alone and affected 38,000 people. Thus, the aim of this study was to use Maxent to identify the areas at risk of huaicos in this department. To this end, a georeferenced database was created that included the locations of these events for modeling. We used variables suggested by Peru’s Geological, Mining, and Metallurgical Institute (INGEMMET)—geology, geomorphology, DEM, slope, and precipitation—which returned extremely high kappa coefficients. Approximately 42% of Lima’s area is likely to have a huaico occurrence. The most crucial variable for the models was the geomorphological classification characterized by the accumulation of mobilized material, as was the case in previous huaico models. In addition, the monthly approach should have been more effective at determining the differences in the precipitation levels. Thus, new models for the coastal departments of Peru using Maxent algorithms should take a new approach related to precipitation, although the use of Maxent proved satisfactory. Full article

The crystal structure of the extracellular region of the second pneumococcal LCP, a polyisoprenyl-teichoic acid-peptidoglycan teichoic acid transferase Psr_Sp, was determined and refined to 2.15 Å resolution. Despite the low sequence homology with other LCP proteins, the Psr_Sp maintains the fold of the LCP domain, and the positions of the residues suggested to participate in the transferase function are conserved. The tunnel found in the Psr_Sp between the central β-sheet and three α-helices is wide enough to accommodate polyisoprenyl-teichoic acid. Comparison of the crystallographic temperature factors of LCP from distinct bacteria demonstrated that the four long loops located close to the teichoic acid and peptidoglycan binding sites have different relative mobilities. To compare the dynamics of the Psr_Sp in crystalline state and in solution, NMR spectra were recorded, and 88% of the residues were assigned in the ¹H-¹⁵N TROSY HSQC spectra. Perfect accordance in the secondary structure of the crystal structure of Psr_Sp with NMR data demonstrated correct assignment. Moreover, the relative mobility of the essential loops estimated from the crystallographic B-factor is in good agreement with order parameter S², predicted from chemical shift. We hypothesize that the dynamics of these loops are important for the substrate promiscuity of LCP proteins. Full article

This study analyses climate variability on the north coast of Peru to understand how the local weather is coupled with anomalous ocean conditions. Using high-resolution satellite reanalysis, statistical outcomes are generated via composite analysis and point-to-field regression. Daily time series data for 1979–2023 for Moche area (8S, 79W) river discharge, rainfall, wind, sea surface temperature (SST) and potential evaporation are evaluated for departures from the average. During dry weather in early summer, the southeast Pacific anticyclone expands, an equatorward longshore wind jet ~10 m/s accelerates off northern Peru, and the equatorial trough retreats to 10N. However, most late summers exhibit increased river discharge as local sea temperatures climb above 27 °C, accompanied by 0.5 m/s poleward currents and low salinity. The wet spell composite featured an atmospheric zonal overturning circulation comprised of lower easterly and upper westerly winds > 3 m/s that bring humid air from the Amazon. Convection is aided by diurnal heating and sea breezes that increase the likelihood of rainfall ~ 1 mm/h near sunset. Wet spells in March 2023 were analyzed for synoptic weather forcing and the advection of warm seawater from Ecuador. Although statistical correlations with Moche River discharge indicate a broad zone of equatorial Pacific ENSO forcing (Nino3 R~0.5), the long-range forecast skill is rather modest for February–March rainfall (R² < 0.2). Full article

This study undertakes a Life Cycle Assessment (LCA) of red and white wine production in Brazil, focusing on a leading winery in the Serra Gaúcha region. Given the notable lack of similar research in this area, our study employs LCA methodologies to evaluate the environmental impacts associated with the winery stage. Our results indicate that although white wine generally exhibits a lower environmental impact than red wine, the specific impacts differ substantially across various environmental categories, highlighting the necessity for context-specific assessments. We also find that electricity consumption, sugar usage, and liquid CO₂ production are the primary drivers of environmental impacts, especially in toxicity-related categories. Moreover, our research critically examines the suitability of the Product Environmental Footprint Category Rules (PEFCR) within the Brazilian context and proposes a revised set of impact categories. This revision enhances the accounted impacts from 55% in the existing PEFCR 2.0 to 80% in our recommended framework, suggesting the need for more tailored environmental impact assessment tools in regional settings. Through these findings, our study not only addresses a significant gap in LCA research within the Brazilian wine industry but also sets the stage for improved environmental management practices across Brazilian wine industries. These enhancements are crucial for aligning local production processes with global sustainability standards and advancing the environmental stewardship of the wine sector in Brazil. Full article

Breast milk holds an immense nutritional value as it contains health-promoting substances in a unique, optimal form. Additionally, breast milk’s significance extends to health and environmental protection, as it serves as an indicator of both maternal and infant exposure. In this study, breast milk samples collected in 2013 and in 2014–2016 from mothers in Vienna (Austria) were analysed for polybrominated diphenyl ethers (PBDE) and per- and polyfluoroalkyl substances (PFAS), as well as further substances which have been listed under the Stockholm Convention on Persistent Organic Pollutants (POPs) due to their persistent, bioaccumulative and toxic properties. The total concentration of the PBDE congeners in the samples (n = 18, sampled 2013) ranged from 0.055 to 52 ng/g lipid, and from 0.002 to 2.5 ng/g breast milk. In the pooled sample, the sum of PBDEs was detected at a level of 4.4 ng/g lipid. Based on the 2014–2016 study population, certain PFAS were detected in all samples (n = 40). Exposure to the sum of four specific PFAS including perfluorooctanesulphonate (PFOS), perfluorooctanoic acid (PFOA), perfluoro-n-nonanoic acid (PFNA) and perfluoro-1-hexanesulfonate (PFHxS) ranged between 0.014 and 0.12 ng/L breast milk. In the pooled sample, PFOS and PFOA were found in concentrations of 0.025 ng/g and of 0.045 ng/g, respectively. In addition, the first generation of POPs, mainly organochlorine compounds, was measured in a pooled sample of breast milk from participants sampled in 2014–2016 as part of the WHO/UNEP breast milk monitoring program and compared to the POPs measured in pooled samples collected in 1987/1988 and 1992/1993, respectively. Therefore, this paper demonstrates the effectiveness of the Stockholm Convention on POPs by comparing the Austrian results from the WHO/UNEP global breast milk study from 1987 to 2016. However, the data also show that, despite these reductions, health-relevant levels are still being reached, particularly in terms of children’s health when the presence of the new generation of POPs, such as PBDEs and PFAS, in human breast milk is taken into account. Full article

The Moche civilization in Peru developed marvelous metallurgy, primarily using alloys of gold, copper and silver, with the most famous of them called Tumbaga, which resembles pure gold after a depletion process on its surface. However, they also created objects with more standard single-layer alloys or gilding. To distinguish between these techniques in a non-destructive manner is essential. Here, we analyzed a thigh protector, composed of two parts, one seemingly in silver and the other seemingly in gold. The sample was analyzed using X-ray fluorescence measurements integrated with Monte Carlo simulation. The results show that the silver part is formed of a silver-based alloy covered in a corrosion layer, while the gold part is made of Tumbaga. Moreover, for the first time, the gold profiles of different Tumbaga gold objects, from the same burial, were compared, allowing us to obtain information about the standardization of their manufacture. Full article

The authors studied forty-three beautiful nose ornaments from the Moche tomb of the Lady of Cao, located in the north of Peru, which has been dated to be around 300–400 d.C. Of these items, thirty-nine are composed of a sheet of gold alloy joined together in various manners to a silver alloy sheet, which provides a strong contrast at their interface. Two nose ornaments are on gold alloy and two on silver alloy. These nose ornaments were studied using the following methods: (i) Energy-dispersive X-ray fluorescence (EDXRF); (ii) Transmission of monoenergetic X-rays (XRT) and (iii) X-ray Radiography (RAD). The conclusion, deduced from all applied methods, was that two sheets of gold and silver alloys were joined together with various methods, including gluing, mechanically joining, soldering, smelting with the aid of heating or using mercury to create an amalgam. It cannot be excluded that a few areas, visibly appearing as silver, were obtained by depletion silvering from the base Au-Cu-Ag alloy. By analyzing a fragment from the silver area of a nose ornament and by studying a few other nose ornaments from the tomb of the Lady of Cao in situ, G. Ingo and co-workers concluded that a unique sheet of three-component alloy (Ag-Cu-Au), whichemployed and transformed the surface of the objects to appear to be gold and silver by depletion gilding and silvering. Full article

This paper presents a comparative study of relationship estimation between intelligence indicators and single-channel and multi-channel feature sets extracted from resting EEG data. In the first case, the power of four frequency bands (alpha, theta, beta, delta) calculated using the discrete Fourier transform (DFT) and the power spectral density (PSD) estimated through the Welch’s method for each of the channels were extracted as features from the EEG signals. In the second case, Imaginary Coherence (iMOCH) measure values for a pair of channels in the frequency bands were extracted. Graph theoretical connectivity metrics were calculated for iMOCH. As part of the experimental part of the study, the data of the EEG records of 79 subjects at rest and the values of four IQ indicators (IQ2—ability to abstract; IQ3—verbal analogies and combinatorial abilities; IQ7—figure detecting, combinatorial abilities; IQ8—spatial imagination) of the structure of intelligence were analyzed by the Amthauer method. For relationship estimation, a principal component regression was used. The performance evaluation is based on the nested Monte-Carlo cross-validation. The single-channel feature set provides the smallest standard deviation of mean absolute error. For non-verbal intelligence, the results of the multi-channel approach are better. For verbal intelligence, on the contrary, the single-channel approach gives the best result. Full article

Due to the COVID-19 pandemic, the tourism sector has been one of the most affected sectors and requires management entities to develop urgent measures to reactivate and achieve digital transformation using emerging disruptive technologies. The objective of this research is to apply machine learning techniques to predict visitors to tourist attractions on the Moche Route in northern Peru, for which a methodology based on four main stages was applied: (1) data collection, (2) model analysis, (3) model development, and (4) model evaluation. Public data from official sources and internet data (TripAdvisor and Google Trends) during the period from January 2011 to May 2022 are used. Four algorithms are evaluated: linear regression, KNN regression, decision tree, and random forest. In conclusion, for both the prediction of national and foreign tourists, the best algorithm is linear regression, and the results allow for taking the necessary actions to achieve the digital transformation to promote the Moche Route and, thus, reactivate tourism and the economy in the north of Peru. Full article

Beaches are major sites of microbiological pollution. Assessment of the abundance of resistant forms of enteric protozoa on these recreational waters is important for the prevention and management of health risks. Based on sedimentation and flotation methods, this study found that Kribi beach waters concentrate considerable amounts of enteric protozoa, which are potentially pathogenic. They include Coccidia (Cryptosporidium sp. and Cyclospora cayetanensis), Amoebae (Endolimax nana, Entamoeba histolytica and Entamoeba coli) and Flagellates (Giardia intestinalis). In general, seasonal changes and tidal cycles have significantly impacted the spread of these parasites along Kribi beaches. Thus, at all sites surveyed (Mpalla, Ngoyè and Mboamanga), maximum protozoan abundances were recorded at low tide and during the rainy seasons. It should also be noted that at each sampling site, significant correlations were recorded between certain protozoa and certain physico-chemical variables (p < 0.05). At Mboamanga, for example, Cryptosporidium sp. and Endolimax nana were positively correlated during the Short Rainy Season with temperature (r = 0.601, p = 0.044 and r = 0.632, p = 0.042). At Mpalla, a positive and significant correlation was observed during the Short Rainy Season between Entamoeba coli and pH (r = 0.605, p = 0.033). The high concentration of resistant forms of these enteric protozoa at Kribi beaches is a real public health threat for bathers. Therefore, in this tourist town, it is urgent to put in place an effective plan for the collection and sustainable treatment of solid and liquid waste, which are the main sources of contamination. Full article

We present a modeling tool capable of computing carbon dioxide (CO₂) fluxes over a non-uniform boreal peatland. The three-dimensional (3D) hydrodynamic model is based on the “one-and-a-half” closure scheme of the system of the Reynolds-Averaged Navier–Stokes and continuity equations. Despite simplifications used in the turbulence description, the model allowed obtaining the spatial steady-state distribution of the averaged wind velocities and coefficients of turbulent exchange within the atmospheric surface layer, taking into account the surface heterogeneity. The spatial pattern of CO₂ fluxes within and above a plant canopy is derived using the “diffusion–reaction–advection” equation. The model was applied to estimate the spatial heterogeneity of CO₂ fluxes over a non-uniform boreal ombrotrophic peatland, Staroselsky Moch, in the Tver region of European Russia. The modeling results showed a significant effect of vegetation heterogeneity on the spatial pattern of vertical and horizontal wind components and on vertical and horizontal CO₂ flux distributions. Maximal airflow disturbances were detected in the near-surface layer at the windward and leeward forest edges. The forest edges were also characterized by maximum rates of horizontal CO₂ fluxes. Modeled turbulent CO₂ fluxes were compared with the mid-day eddy covariance flux measurements in the southern part of the peatland. A very good agreement of modeled and measured fluxes (R² = 0.86, p < 0.05) was found. Comparisons of the vertical profiles of CO₂ fluxes over the entire peatland area and at the flux tower location showed significant differences between these fluxes, depending on the prevailing wind direction and the height above the ground. Full article

An attempt was made, using computational methods, to understand whether the intermolecular interactions in the dimers of molybdenum dichalcogenides MoCh₂ (Ch = chalcogen, element of group 16, especially S, Se and Te) and similar mixed-chalcogenide derivatives resemble the room temperature experimentally observed interactions in the interfacial regions of molybdenites and their other mixed-chalcogen derivatives. To this end, MP2(Full)/def2-TVZPPD level electronic structure calculations on nine dimer systems, including (MoCh₂)₂ and (MoChCh′₂)₂ (Ch, Ch′ = S, Se and Te), were carried out not only to demonstrate the energetic stability of these systems in the gas phase, but also to reproduce the intermolecular geometrical properties that resemble the interfacial geometries of 2D layered MoCh₂ systems reported in the crystalline phase. Among the six DFT functionals (single and double hybrids) benchmarked against MP2(full), it was found that the double hybrid functional B2PLYPD3 has some ability to reproduce the intermolecular geometries and binding energies. The intermolecular geometries and binding energies of all nine dimers are discussed, together with the charge density topological aspects of the chemical bonding interactions that emerge from the application of the quantum theory of atoms in molecules (QTAIM), the isosurface topology of the reduced density gradient noncovalent index, interaction region indicator and independent gradient model (IGM) approaches. While the electrostatic surface potential model fails to explain the origin of the S···S interaction in the (MoS₂)₂ dimer, we show that the intermolecular bonding interactions in all nine dimers examined are a result of hyperconjugative charge transfer delocalizations between the lone-pair on (Ch/Ch′) and/or the π-orbitals of a Mo–Ch/Ch′ bond of one monomer and the d_π* anti-bonding orbitals of the same Mo–Ch/Ch′ bond in the second monomer during dimer formation, and vice versa. The HOMO–LUMO gaps calculated with the MN12-L functional were 0.9, 1.0, and 1.1 eV for MoTe₂, MoSe₂ and MoS₂, respectively, which match very well with the solid-state theoretical (SCAN-rVV10)/experimental band gaps of 0.75/0.88, 0.90/1.09 and 0.93/1.23 eV of the corresponding systems, respectively. We observed that the gas phase dimers examined are perhaps prototypical for a basic understanding of the interfacial/inter-layer interactions in molybdenum-based dichalcogenides and their derivatives. Full article

Medication management in residential aged care facilities (RACFs) is complex and often sub-optimal. Pharmacist practice models and services have emerged internationally to address medication-related issues in RACFs. This narrative review aimed to explore pharmacist practice models in aged care in Australia, England and the USA, and identify key activities and characteristics within each model. A search strategy using key terms was performed in peer-reviewed databases, as well as the grey literature. Additionally, experts from the selected countries were consulted to obtain further information about the practice models in their respective countries. Thirty-six documents met the inclusion criteria and were included in the review. Four major pharmacist practice models were identified and formed the focus of the review: (1) the NHS’s Medicine Optimisation in Care Homes (MOCH) program from England; (2) the Australian model utilising visiting accredited pharmacists; (3) the Centers for Medicare and Medicaid (CMS) pharmacy services in long-term care from the USA; and (4) the Medication Therapy Management (MTM) program from the USA. Medication reviews were key activities in all models, but each had distinct characteristics in relation to the comprehensiveness, who is eligible, and how frequently residents receive medication review activity. There was heterogeneity in the types of facility-level activities offered by pharmacists, and further research is needed to determine the effectiveness of these activities in improving quality use of medicines in the aged care setting. This review found that in some models, pharmacists have a limited level of collaboration with other healthcare professionals, emphasising the need to trial innovative models with integrated services and increased collaboration to achieve a holistic patient-centred approach to medication management. Full article

Pharmacists and pharmacy technicians seek to improve person-centred care. Improvements to systems for care homes seeks to reduce medicines waste and inefficiency, particularly through supporting care home staff, to enhance safer administration of medicines. A complex evaluation used qualitative design and utilised narrative enquiry, and team members and key stakeholders were interviewed. Framework analysis was used, aligning findings to a person-centred care framework for older people. The Medicines Optimisation in Care Homes (MOCH) team brokered improvement practices across care homes to enhance person-centred care. The framework analysis confirms that the team used ‘authentic attention’ in relation to the residents’ experiences and flexibility in relation to negotiating medication. The importance of transparency of processes and systems in medicines management is highlighted, alongside requirements for person-centred care to make explicit the reason for taking a medication, and the continuous discussion with a range of stakeholders about the continuing need for particular medications. The outcome of the evaluation includes insights into a new area of pharmacy practice in community, based on the skills, knowledge, and experience of pharmacists and pharmacy technicians working in the care home sector. Further study is needed into the efficacy and outcomes of medicines management interventions. Full article

Bats are depicted in various types of media in Central and South America. The Moche of northern Peru portrayed bats in many figurative ceramic vessels in association with themes of sacrifice, elite status and agricultural fertility. Osseous remains of bats in Moche ceremonial and domestic contexts are rare yet their various representations in visual media highlight Moche fascination with their corporeal form, behaviour and symbolic meaning. By exploring bat imagery in Moche iconography, I argue that the bat formed an important part of Moche categorical schemes of the non-human world. The bat symbolized death and renewal not only for the human body but also for agriculture, society and the cosmos. I contrast folk taxonomies and symbolic classification to interpret the relational role of various species of chiropterans to argue that the nocturnal behaviour of the bat and its symbolic association with the moon and the darkness of the underworld was not a negative sphere to be feared or rejected. Instead, like the representative priestesses of the Late Moche period, bats formed part of a visual repertoire to depict the cycles of destruction and renewal that permitted the cosmological continuation of life within North Coast Moche society. Full article