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112 Results Found

  • Article
  • Open Access
8 Citations
3,928 Views
19 Pages

Epigenetic Silencing of LMX1A Contributes to Cancer Progression in Lung Cancer Cells

  • Ti-Hui Wu,
  • Shan-Yueh Chang,
  • Yu-Lueng Shih,
  • Chih-Feng Chian,
  • Hung Chang and
  • Ya-Wen Lin

Epigenetic modification is considered a major mechanism of the inactivation of tumor suppressor genes that finally contributes to carcinogenesis. LIM homeobox transcription factor 1α (LMX1A) is one of the LIM-homeobox-containing genes that is a...

  • Article
  • Open Access
7 Citations
3,324 Views
18 Pages

Lmx1a-Dependent Activation of miR-204/211 Controls the Timing of Nurr1-Mediated Dopaminergic Differentiation

  • Salvatore Pulcrano,
  • Roberto De Gregorio,
  • Claudia De Sanctis,
  • Laura Lahti,
  • Carla Perrone-Capano,
  • Donatella Ponti,
  • Umberto di Porzio,
  • Thomas Perlmann,
  • Massimiliano Caiazzo and
  • Gian Carlo Bellenchi
  • + 1 author

The development of midbrain dopaminergic (DA) neurons requires a fine temporal and spatial regulation of a very specific gene expression program. Here, we report that during mouse brain development, the microRNA (miR-) 204/211 is present at a high le...

  • Article
  • Open Access
11 Citations
3,406 Views
13 Pages

Transcription Factor Lmx1b Negatively Regulates Osteoblast Differentiation and Bone Formation

  • Kabsun Kim,
  • Jung Ha Kim,
  • Inyoung Kim,
  • Semun Seong,
  • Jeong Eun Han,
  • Keun-Bae Lee,
  • Jeong-Tae Koh and
  • Nacksung Kim

The LIM-homeodomain transcription factor Lmx1b plays a key role in body pattern formation during development. Although Lmx1b is essential for the normal development of multiple tissues, its regulatory mechanism in bone cells remains unclear. Here, we...

  • Article
  • Open Access
3 Citations
2,903 Views
17 Pages

19 June 2022

From the perspective of social relationships, this study extends the understanding of employee voice by examining voice outcomes, especially a voicer’s influence in their work team. In particular, we explore how two different social relationshi...

  • Article
  • Open Access
22 Citations
5,371 Views
18 Pages

From LMX to Individual Creativity: Interactive Effect of Engagement and Job Complexity

  • Guadalupe Vila-Vázquez,
  • Carmen Castro-Casal and
  • Dolores Álvarez-Pérez

This study explores how the quality of leader–member exchange (LMX) is associated with employees’ creativity via engagement, and the moderating role of a job characteristic related to knowledge (job complexity) in this relationship. A mod...

  • Article
  • Open Access
5 Citations
3,569 Views
13 Pages

Psychometric Properties of the Italian Version of the Leader Member Exchange Scale (LMX-7): A Validation Study

  • Marzia Lommi,
  • Ippolito Notarnicola,
  • Rosario Caruso,
  • Laura Iacorossi,
  • Francesca Gambalunga,
  • Laura Sabatino,
  • Roberto Latina,
  • Teresa Rea,
  • Assunta Guillari and
  • Dhurata Ivziku
  • + 6 authors

For decades, scholars have studied leader–member exchange (LMX) relationships to understand and explain the effects of leadership on follower attitudes and performance outcomes within work settings. One available instrument to measure these asp...

  • Article
  • Open Access
9 Citations
9,680 Views
20 Pages

23 November 2024

In the context of the New Normal and the VUCA (volatile, uncertain, complex, ambiguous) era, organisations face adjustments to the changes brought by the COVID-19 pandemic, especially the shifting to new work modes and configurations with their conse...

  • Article
  • Open Access
6 Citations
2,712 Views
9 Pages

LMX1B Locus Associated with Low-Risk Baseline Glaucomatous Features in the POAAGG Study

  • Elana Meer,
  • Vivian L. Qin,
  • Harini V. Gudiseva,
  • Brendan McGeehan,
  • Rebecca Salowe,
  • Maxwell Pistilli,
  • Jie He,
  • Ebenezer Daniel,
  • Gui Shang Ying and
  • Joan M. O’Brien
  • + 1 author

16 August 2021

Primary open-angle glaucoma (POAG) is the leading cause of irreversible blindness worldwide and has been associated with multiple genetic risk factors. The LMX1B gene is a genetic susceptibility factor for POAG, and several single-nucleotide polymorp...

  • Article
  • Open Access
12 Citations
5,250 Views
15 Pages

22 November 2019

The purpose of this quantitative field study is to examine the relationship between perceived leader narcissism and employee proactive behavior, incorporating leader–member exchange (LMX) quality and leader identification as moderators. Within...

  • Article
  • Open Access
6 Citations
7,526 Views
11 Pages

A Microdeletion of Chromosome 9q33.3 Encompasses the Entire LMX1B Gene in a Chinese Family with Nail Patella Syndrome

  • Shujuan Jiang,
  • Jiubin Zhang,
  • Dan Huang,
  • Yuanyuan Zhang,
  • Xiaoliang Liu,
  • Yinzhao Wang,
  • Rong He and
  • Yanyan Zhao

5 November 2014

Nail patella syndrome (NPS) is an autosomal dominant disorder characterized by nail malformations, patellar apoplasia, or patellar hypoplasia. Mutations within the LMX1B gene are found in 85% of families with NPS; thus, this gene has been characteriz...

  • Article
  • Open Access
14 Citations
10,399 Views
23 Pages

25 July 2024

Rapid organizational changes due to technological advancements, high-efficiency expectations, and uncertainties, particularly in healthcare, have led to a global stress epidemic among em-ployees. This has been exacerbated by the COVID-19 pandemic and...

  • Article
  • Open Access
1,402 Views
16 Pages

AMPK Phosphorylates LMX1b to Regulate a Brainstem Neurogenic Network Important for Control of Breathing in Neonatal Mice

  • Traci L. Marin,
  • Christopher G. Wilson,
  • Miguel Lopez Ramirez,
  • Wei Sun,
  • Atul Malhotra and
  • Brendan Gongol

30 December 2024

Ventilatory drive is modulated by a variety of neurochemical inputs that converge on spatially oriented clusters of cells within the brainstem. This regulation is required to maintain energy homeostasis and is essential to sustain life across all mam...

  • Article
  • Open Access
4 Citations
2,550 Views
18 Pages

22 October 2023

This study has two purposes. The first is to determine whether subordinates employ alternative combinations of emotion regulation strategies toward their supervisors beyond merely using surface and deep labor from the person-centered perspective. The...

  • Article
  • Open Access
10 Citations
3,348 Views
16 Pages

26 April 2020

Previous studies have found that LMX1B rs10733682 polymorphism is associated with Body Mass Index (BMI) in European and American Indian adults. In this study, the association of rs10733682 polymorphism with obesity-related indicators, and its interac...

  • Article
  • Open Access
337 Views
22 Pages

2 January 2026

This study explores the relationship between Leader-Member Exchange (LMX) quality and team cohesion within the Croatian banking sector. Drawing from relationship-based leadership theories, we investigate how the quality of dyadic relationships betwee...

  • Article
  • Open Access
16 Citations
5,208 Views
20 Pages

Psychological Safety in Ghana: Empirical Analyses of Antecedents and Consequences

  • Mavis Agyemang Opoku,
  • Suk Bong Choi and
  • Seung-Wan Kang

This study examines psychological safety as a mediator in the relationship between Leader–Member Exchange (LMX) and voice behavior. Based on the conservation of resources theory, a moderated mediation framework was used to examine human capital...

  • Article
  • Open Access
985 Views
21 Pages

10 November 2025

Leader–member relationships shape public sector performance, yet how leader–member exchange (LMX) operates through capability and motivation pathways remains underexplored. Drawing on social information processing and career construction...

  • Article
  • Open Access
10 Citations
3,785 Views
10 Pages

8 August 2019

Whereas past research on daily job crafting has tended to focus on how job crafting affected employee behaviors, we extend this study by examining the antecedents of job crafting and cross-level moderators such as leader-member exchange (LMX) and res...

  • Article
  • Open Access
3 Citations
3,211 Views
15 Pages

When practicing high-quality leader–member exchange (LMX) theory, the leader’s ability to communicate, build and maintain relationships is a vital part. Because leader–member exchange theory is a relationship-based approach to leade...

  • Article
  • Open Access
9 Citations
6,728 Views
14 Pages

13 December 2021

This study investigates linear and non-linear associations among work tenure, organizational tenure, and organizational citizenship behaviors (OCB), and between leader–member exchange (LMX) and OCBs. A deductive approach was employed to collect...

  • Article
  • Open Access
18 Citations
4,575 Views
18 Pages

Cerebral-Organoid-Derived Exosomes Alleviate Oxidative Stress and Promote LMX1A-Dependent Dopaminergic Differentiation

  • Xingrui Ji,
  • Shaocong Zhou,
  • Nana Wang,
  • Jingwen Wang,
  • Yue Wu,
  • Yuhan Duan,
  • Penghao Ni,
  • Jingzhong Zhang and
  • Shuang Yu

The remarkable advancements related to cerebral organoids have provided unprecedented opportunities to model human brain development and diseases. However, despite their potential significance in neurodegenerative diseases such as Parkinson’s d...

  • Article
  • Open Access
89 Citations
16,316 Views
20 Pages

26 November 2018

The current study objective is to investigate how and when leader member exchange (LMX), tie strength, and innovative organizational culture influences employee innovative behavior. In particular, this study uses the social exchange theory to analyze...

  • Article
  • Open Access
19 Citations
4,601 Views
14 Pages

A Novel Prognostic DNA Methylation Panel for Colorectal Cancer

  • Hsin-Hua Chung,
  • Chih-Chi Kuo,
  • Cheng-Wen Hsiao,
  • Chao-Yang Chen,
  • Je-Ming Hu,
  • Chih-Hsiung Hsu,
  • Yu-Ching Chou,
  • Ya-Wen Lin and
  • Yu-Lueng Shih

20 September 2019

Colorectal cancer (CRC) is one of the most common cancers and the second leading cause of cancer-related deaths. Discrepancies in clinical outcomes are observed even among patients with same-stage CRC due to molecular heterogeneity. Thus, biomarkers...

  • Article
  • Open Access
15 Citations
4,425 Views
20 Pages

13 January 2023

The sustainable competitiveness of an organization is largely dependent upon its effectiveness in developing and maintaining high levels of socializees’ work engagement. Based on COR (conservation of resources) theory, the present study propose...

  • Article
  • Open Access
6 Citations
3,295 Views
18 Pages

14 December 2023

This study delves into the assessment of the quality of social exchange relationships in the workplace, specifically focusing on leader–member exchange (LMX) and team–member exchange (TMX), to forecast employee Total Quality Management (T...

  • Article
  • Open Access
1,105 Views
12 Pages

4 June 2025

The definitive demonstration of effective leadership is the ability to communicate with purpose in such a way that gives life to ideas and accomplishes organizational objectives. God’s message of grace to humanity was the Word, his Son Jesus Ch...

  • Article
  • Open Access
5 Citations
5,495 Views
24 Pages

Emotional Contagion in the Hospitality Industry: Unraveling Its Impacts and Mitigation Strategies Through a Moderated Mediated PLS-SEM Approach

  • Ibrahim A. Elshaer,
  • Alaa M. S. Azazz,
  • Mansour Alyahya,
  • Abuelkassem A. A. Mohammad,
  • Sameh Fayyad and
  • Osman Elsawy

Emotional contagion is a common phenomenon among hotel employees, creating an environment of shared emotions that can influence work-related outcomes such as job performance, job satisfaction, and psychological well-being. However, strategies to miti...

  • Article
  • Open Access
6 Citations
4,614 Views
13 Pages

Leadership is about lifting a person’s vision, raising their productivity to higher standards and creating a personality beyond their usual capabilities. Our study examines the Pygmalion effect and leader-member exchange (LMX) on employee task...

  • Article
  • Open Access
44 Citations
8,238 Views
14 Pages

Drawing on social identity theory, this study examines the effect of servant leadership on university teachers’ innovative behavior through the self-concept constructs of perceived insider status and organization-based self-esteem, and the mode...

  • Article
  • Open Access
23 Citations
7,766 Views
17 Pages

Developing Sustainable Careers during a Pandemic: The Role of Psychological Capital and Career Adaptability

  • Jetmir Zyberaj,
  • Sebastian Seibel,
  • Annika F. Schowalter,
  • Lennart Pötz,
  • Stefanie Richter-Killenberg and
  • Judith Volmer

7 March 2022

The Coronavirus disease 2019 (COVID-19) has not only had negative effects on employees’ health, but also on their prospects to gain and maintain employment. Using a longitudinal research design with two measurement points, we investigated the r...

  • Article
  • Open Access
28 Citations
5,720 Views
25 Pages

24 December 2019

In this mixed methods study, a moderated mediation model predicting effects of leader-member exchange (LMX) and organizational citizenship behaviors (OCB) on innovative work behaviors, with employability as a mediator, has been tested. Multi-source d...

  • Article
  • Open Access
1,109 Views
38 Pages

Organizational Innovation and Managerial Burnout: Implications for Well-Being and Social Sustainability in a Transition Economy

  • Verica Gluvakov,
  • Mila Kavalić,
  • Milan Nikolić,
  • Dragan Ćoćkalo,
  • Sanja Stanisavljev and
  • Snežana Mirković

23 November 2025

This study explores the relationship between organizational innovation and managerial burnout among middle managers in Serbia, a country undergoing socioeconomic transition. Data were collected from 406 managers using a standardized questionnaire and...

  • Article
  • Open Access
1,405 Views
17 Pages

27 September 2025

Most academic work concludes that supervisors are typically viewed as providers rather than seekers of emotional support, as emotional support-seeking may be seen as a threat to their status in the workplace. However, this conclusion is incomplete du...

  • Article
  • Open Access
1,822 Views
26 Pages

21 March 2024

Serial sectioning and 3D image reconstruction methods were applied to elucidate the structures of the apices of root vascular cylinders (VCs) in taxa of the Poaceae: Zea mays “Honey Bantam”, Z. mays ssp. mexicana, Hordeum vulgare and Oryz...

  • Article
  • Open Access
19 Citations
6,551 Views
20 Pages

Employee Voice: A Mechanism to Harness Employees’ Potential for Sustainable Success

  • Hengwei Zhu,
  • Muhammad Kamran Khan,
  • Shakira Nazeer,
  • Li Li,
  • Qinghua Fu,
  • Daniel Badulescu and
  • Alina Badulescu

Listening to employees’ concerns reduces their dissatisfaction, but moreover, for an organization to achieve sustainable success, employees must raise their creative voice and give their input in decision-making without the fear of rejection in...

  • Article
  • Open Access
29 Citations
6,843 Views
12 Pages

This study investigated the relationships between leader–member exchange (LMX) and workers’ perceptions of family–work conflict (FWC) and between LMX and satisfaction with remote working (SRW). It also assessed the moderating effect...

  • Article
  • Open Access
8 Citations
4,662 Views
15 Pages

2 January 2023

This study investigates how leadership, more precisely leader–member exchange (LMX), affects innovative behavior through an innovative climate as well as, indirectly, through organizational commitment and internal trust. A total of 1114 samples...

  • Article
  • Open Access
20 Citations
5,625 Views
16 Pages

Culture, Work, and Subjective Well-Being: The Role of LMX and Resilience in Spanish and Chinese Cultures

  • Pilar González-Navarro,
  • Elena Talavera-Escribano,
  • Rosario Zurriaga-Lloréns and
  • Lucía I. Llinares-Insa

Globalization and interdependencies among nations require a better understanding of the influence of culture on organizational processes. In order to succeed in global business, leaders have to respond to practices that may be different in diverse cu...

  • Article
  • Open Access
8 Citations
2,710 Views
15 Pages

Sensorineural hearing loss is one of the most common inherited sensory disorders. Functional classifications of deafness genes have shed light on genotype- and mechanism-based pharmacological approaches and on gene therapy strategies. In this study,...

  • Review
  • Open Access
8 Citations
5,832 Views
21 Pages

7 August 2021

Four sensory systems (vestibular, lateral line, electroreception, auditory) are unique and project exclusively to the brainstem of vertebrates. All sensory neurons depend on a common set of genes (Eya1, Sox2, Neurog1, Neurod1) that project to a dorsa...

  • Article
  • Open Access
26 Citations
13,157 Views
18 Pages

12 May 2021

Continuous innovation has become a key to gaining a sustainable competitive advantage for organizations in the 21st century. By focusing on the underlying mechanisms (i.e., mindfulness and work engagement) by which it works, this study addresses the...

  • Article
  • Open Access
13 Citations
4,124 Views
14 Pages

LmxM.22.0250-Encoded Dual Specificity Protein/Lipid Phosphatase Impairs Leishmania mexicana Virulence In Vitro

  • Natalya Kraeva,
  • Tereza Leštinová,
  • Aygul Ishemgulova,
  • Karolina Majerová,
  • Anzhelika Butenko,
  • Slavica Vaselek,
  • Julia Bespyatykh,
  • Arzuv Charyyeva,
  • Tatiana Spitzová and
  • Vyacheslav Yurchenko
  • + 4 authors

17 November 2019

Protein phosphorylation/dephosphorylation is an important regulatory mechanism that controls many key physiological processes. Numerous pathogens successfully use kinases and phosphatases to internalize, replicate, and survive, modifying the host&pri...

  • Article
  • Open Access
681 Views
26 Pages

Reservoir Characteristics and Influencing Factors of Different Lithofacies of WF-LMX Formation Shale in Zigong Area, Sichuan Basin

  • Changchang Wang,
  • Qinghai Xu,
  • Litao Xu,
  • Fancheng Zeng,
  • Huan Li,
  • Zhicheng Huang,
  • Jiayi Li,
  • Kun Wang and
  • Mengyuan Li

An integrated analysis including total organic carbon (TOC), X-ray diffraction (XRD), scanning electron microscopy (SEM), and gas adsorption experiments was conducted on core samples from the deep Wufeng–Longmaxi (WF-LMX) Formation in the Zigon...

  • Article
  • Open Access
12 Citations
4,780 Views
24 Pages

Complex Cause-Effect Relationships of Social Capital, Leader-Member Exchange, and Safety Behavior of Workers in Small-Medium Construction Firms and the Moderating Role of Age

  • Marchel Bentoy,
  • Marlon Mata,
  • Jayson Bayogo,
  • Roel Vasquez,
  • Rose Mary Almacen,
  • Samantha Shane Evangelista,
  • Charldy Wenceslao,
  • Jannen Batoon,
  • Maria Diana Lauro and
  • Lanndon Ocampo
  • + 3 authors

30 September 2022

Due to workers’ vulnerability in construction sites, workplace safety has become of particular interest, and the current literature offers myriad approaches to dealing with it. From a social and organizational lens, this study explores an empir...

  • Article
  • Open Access
4 Citations
2,395 Views
15 Pages

3 October 2023

Do victims really help their abusive supervisors? Does abusive supervision have any positive consequence? The study aims to address this concern through extending the work by Tröster and Van Quaquebeke (2021). Using subordinates’ self-repo...

  • Article
  • Open Access
40 Citations
10,009 Views
17 Pages

Envy and Counterproductive Work Behavior: The Moderation Role of Leadership in Public and Private Organizations

  • Pilar González-Navarro,
  • Rosario Zurriaga-Llorens,
  • Adekunle Tosin Olateju and
  • Lucía I. Llinares-Insa

Envy is a frequent emotion in work contexts where there is strong competition for resources and the leader is the person who manages them. When employees feel envy, they are likely to use counterproductive work behaviors (CWB), but the use of these b...

  • Article
  • Open Access
4 Citations
1,964 Views
16 Pages

10 May 2023

Marine organic-rich shale is widely distributed in the Upper Ordovician Wufeng Formation (WF-F) and Silurian Longmaxi Formation (LMX-F), making it an important target for shale gas exploration and development. In order to clarify the paleoenvironment...

  • Article
  • Open Access
6 Citations
2,778 Views
12 Pages

9 September 2022

Considering that the role of leadership is still essential for a corporate organization to grow and develop continuously, self-leadership based on a sense of ownership is emerging as the ideal leadership required of organizational members. However, d...

  • Article
  • Open Access
8 Citations
5,212 Views
14 Pages

17 April 2020

In order to better understand the social aspects of job crafting, this study explores the direct and interactive effects of leader–member exchange (LMX) and team-member exchange (TMX) on three types of job crafting (i.e., task, relational, and...

  • Article
  • Open Access
1 Citations
1,368 Views
27 Pages

16 October 2025

Perceived organizational support (POS) is critical for fostering discretionary service behaviors, particularly in demanding contexts such as luxury hospitality. This study examines how POS influences extra-role behavior (ERB) among frontline hotel em...

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