Bayesian networks (BNs) are popular models that represent complex relationships among variables. In the discrete case, these relationships can be quantified by conditional probability tables (CPTs). CPTs can be derived from data, but if data are not...
Type 2 diabetes (T2D) results from impaired beta-cell function and insufficient beta-cell mass compensation in the setting of insulin resistance. Current therapeutic strategies focus their efforts on promoting the maintenance of functional beta-cell...
Background: Delays in treatments are frequent in real-world lymphoma management. This study evaluates the impact of diagnosis-to-treatment intervals (DTIs) and first inter-cycle delay (IcD) on outcomes in patients with Hodgkin lymphoma (HL) receiving...
Alzheimer’s disease (AD) is the most prevalent cause of dementia in the elderly, characterized by the presence of amyloid-beta (Aβ) plaques, neurofibrillary tangles, neuroinflammation, synapse loss and neurodegeneration in the brain. The a...
Background: This study investigates the electrophysiological (EEG) correlates underlying negotiation dynamics in dyads engaged in a shared decision-making process. Methods: Using EEG hyperscanning, we examined single-brain and inter-brain neural acti...
Background: In handball, the kinematics of the frontal plane seem to be one of the most important factors for the development of lower limb injuries. The knee valgus angle is a fundamental axis for injury prevention and is usually measured with 2D sy...
Communication can be considered as a joint action that involves two or more individuals transmitting different information. In particular, non-verbal communication involves body movements used to communicate different information, characterized by th...
The malfunctioning of the brain synucleins is associated with pathogenesis of Parkinson’s disease. Synucleins’ ability to modulate various pre-synaptic processes suggests their modifying effects on the electroencephalogram (EEG) recorded...
The beta-3 adrenergic receptor (β3-AR) is by far the least studied isotype of the beta-adrenergic sub-family. Despite its study being long hampered by the lack of suitable animal and cellular models and inter-species differences, a substantial b...
Radon (Rn) is a radioactive, colourless, odourless, noble gas that decays rapidly. It’s most stable isotope, 222Rn, has a half-life of around 3.8 days. Atmospheric radon measurements play an important role in understanding our atmospheric envir...
Sea beet (Beta vulgaris L. subsp. maritima (L.) Arcang.) is a wild member of the Amaranthaceae family and a progenitor for all the cultivated beets (Beta vulgaris subsp. vulgaris). It is a source of stress-resistant genes, contributing 21 valuable tr...
Gas-chromatography/mass-spectrometry and sensory descriptive analyses were applied to provide new data on volatile and olfactory properties of Aglianico and Primitivo (Zinfandel), Italian red wines of growing interest. The relationships between data...
Objectives: The effects of aging such as osteophyte formation, acral shape changes, cortical tunneling, and bone porosity as well as enthesophytes can be studied in the X-rays of hands. However, during the interpretation of radiographs of the hands,...
Biocompatible materials fabricated from natural protein polymers are an attractive alternative to conventional petroleum-based plastics. They offer a green, sustainable fabrication method while also opening new applications in biomedical sciences. Av...
Forest structure, including trees, deadwood and tree-related microhabitats, is a key determinant of forest biodiversity. Their relative contribution in shaping local (alpha) biodiversity and its variation (beta) between sites remains unclear. We asse...
Precision agriculture is about applying solutions that serve to obtain a high yield from the optimization of resources and the development of technologies based on the collection and use of precise data. Precision agriculture, including camera-guided...
Neutrinoless double beta decay is a pivotal weak nuclear process that holds the potential to unveil the Majorana nature of neutrinos and predict their absolute masses. In this study, we delve into examining the impact of spin-dependent short-range co...
We focused on job interviews as critical examples of complex social interaction in organizational contexts. We aimed at investigating the effect of face-to-face vs. computer-mediated interaction, of role (candidate, recruiter), and of the interview p...
Background: developmental dysplasia of the hip has an incidence of 3–5 out of 1000 children. Currently, only postnatal screening is available. Objective: to test the feasibility of a method based on Graf technique application at antenatal ultrasound...
Alzheimer’s disease is a neurodegenerative disorder for which there is a continuous search of drugs able to reduce or stop the cognitive decline. Beta-amyloid peptides are composed of 40 and 42 amino acids and are considered a major cause of ne...
Archaea have been identified as early colonizers of the human intestine, appearing from the first days of life. It is hypothesized that the origin of many of these archaea is through vertical transmission during breastfeeding. In this study, we aimed...
Fusarium avenaceum and closely related species are common fungi on various plants, cultivated in different climatic regions. The aim of this study was to determine the taxonomic affiliations of the F. avenaceum, Fusarium arthrosporioides, and Fusariu...
Understanding how intrinsic brain networks adapt to cognitive demands is central to neuroscience. The aim of this study was to examine how eyes-open and eyes-closed resting-state network integration, derived from electroencephalography before and aft...
Meropenem (MRP)-Vaborbactam (VBR) is a novel beta-lactam/beta-lactamase inhibitor used for the management of difficult-to-treat Gram-negative infections. Among critically ill patients, MRP-VBR shows remarkable inter-individual variability in pharmaco...
Reactive postprandial hypoglycemia (RPH) is an understudied condition that lacks clinical definition, knowledge of future health implications, and an understanding of precise underlying mechanisms. Therefore, our study aimed to assess the glycemic re...
Subthalamic nucleus (STN) local field potentials (LFP) are neural signals that have been shown to reveal motor and language behavior, as well as pathological parkinsonian states. We use a research-grade implantable neurostimulator (INS) with data col...
Recent experiments with amyloid-beta (Aβ) peptides indicate that the formation of toxic oligomers may be an important contribution to the onset of Alzheimer’s disease. The toxicity of Aβ oligomers depend on their structure, which is governed by assem...
By using earthquake catalogs, previous studies have reported evidence that some changes in the spatial and temporal organization of earthquake activity are observed before and after of a main shock. These previous studies have used different approach...
Background: Since the beginning of the COVID-19 pandemic, several SARS-CoV-2 variants have sequentially emerged. In France, most cases were due to spike D641G-harbouring viruses that descended initially from the Wuhan strain, then by the variant of B...
The cortical response to transcranial magnetic stimulation (TMS) has notable inter-trial variability. One source of this variability can be the influence of the phase and power of pre-stimulus neuronal oscillations on single-trial TMS responses. Here...
The relationship between caffeine and insulin resistance (IR) has been assessed only in terms of caffeine intake, and the association between caffeine and beta cell function (BCF) remains unclear. This study examines the association between urinary c...
To explore the effects of immunotherapy in the International Society of Paediatric Oncology Europe Neuroblastoma Group SIOPEN high-risk neuroblastoma 1 trial (HR-NBL1 trial), two cohorts were studied: one prior to and one after the introduction of di...
The Second Generation Global Imager (SGLI) on Global Change Observation Mission–Climate (GCOM-C) satellite empowers surface and atmospheric measurements related to the carbon cycle and radiation budget, with two radiometers of Visible and Near...
This research explored the influence of interoception and social frame on the coherence of inter-brain electrophysiological (EEG) and hemodynamic (collected by functional Near Infrared Spectroscopy, fNIRS) functional connectivity during a motor synch...
Gut microbiota composition plays a crucial role in host health and may be influenced by age and disease conditions. This study investigates the gut microbiota diversity of 175 dogs across three age groups (Junior (20–46 months, 43 dogs), Adult...
People living with HIV (PLWH) age with an excess burden of comorbidities that may increase the incidence of age-related complications. There is controversy surrounding the hypothesis that HIV can accelerate neurodegeneration and Alzheimer’s dem...
Polyaniline/Au nanocomposites were synthesized by a novel method. Aniline monomers were loaded in the hydrophobic cavities of beta-cyclodextrin, and a polymerization reaction occurred at the interface of the beta-cyclodextrin cavities and the liquid...
Colorectal cancer (CRC) is a frequent, worldwide tumor described for its huge complexity, including inter-/intra-heterogeneity and tumor microenvironment (TME) variability. Intra-tumor heterogeneity and its connections with metabolic reprogramming an...
Antimicrobial resistance (AMR) is one of the greatest challenges facing humanity, causing a substantial burden to the global healthcare system. AMR in Gram-negative organisms is particularly concerning due to a dramatic rise in infections caused by e...
Protein folding is a complicated phenomenon including various time scales (μs to several s), and various structural indices are required to analyze it. The methodologies used to study this phenomenon also have a wide variety and employ various exp...
Giardia intestinalis is an intestinal protozoan most commonly found in humans. It has been grouped into 8 assemblages (A-H). Markers such as the glutamate dehydrogenase gene, triose phosphate isomerase and beta-giardin (β-giardin) have been wide...
Several professional societies advise against using real-time Reverse-Transcription PCR (rtRT-PCR) cycle threshold (Ct) values to guide clinical decisions. We comparatively assessed the variability of Ct values generated by six diagnostic approaches...
Seasonal variation in the faecal microbiota of forage-fed horses was investigated over a 12-month period to determine whether the bacterial diversity fluctuated over time. Horses (n = 10) were maintained on pasture for one year, with hay supplemented...
Severe acute respiratory symptom coronavirus 2 (SARS-CoV-2) infection occurs via the attachment of the spike (S) protein’s receptor binding domain (RBD) to human ACE2 (hACE2). Natural polymorphisms in hACE2, particularly at the interface, may a...
The aim of this paper is to present a stochastic model to generate sub-hourly rainfall events at a given point. Historical events used as the input have been extracted by the sub-hourly rainfall series available for a defined rain gauge station based...
On the background of the exponential growth of the world’s population, doubled by the decrease of natural resources and the continuous, accentuated degradation of the quality of the environment, with global warming as its main effect, ensuring...
Background: Electroencephalography (EEG) offers millisecond-precision measurement of neural oscillations underlying human cognition and emotion. Despite extensive research, systematic frameworks mapping EEG metrics to psychological constructs remain...
This study aims to investigate the interactions appearing when the beta-2-glycoprotein-1 binds to a lipid bilayer. The inter- and intra-molecular forces acting between the two macromolecular systems have been investigated using a molecular dynamics s...
Cotton leafroll dwarf virus (CLRDV) is an emerging aphid-borne pathogen infecting cotton, Gossypium hirsutum L., in the southern United States (U.S.). The cotton aphid, Aphis gossypii Glover, infests cotton annually and is the only known vector to tr...
Brucellosis remains a major global public health concern, with B. melitensis and B. abortus being the primary causative agents in China. This study describes the development of a multiplex droplet digital PCR (ddPCR) assay for the simultaneous detect...
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