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  • Article
  • Open Access
13 Citations
4,834 Views
10 Pages

A Randomized Controlled Trial Comparing Ambu AuraGain and i-gel in Young Pediatric Patients

  • Ha-Jung Kim,
  • Hee-Sun Park,
  • Soo-Young Kim,
  • Young-Jin Ro,
  • Hong-Seuk Yang and
  • Won Uk Koh

16 August 2019

Supraglottic airway devices have been increasingly used because of their several advantages. Previous studies showed that the small-sized i-gel provides effective ventilation for young pediatric patients; however, few studies have reported the use of...

(This article belongs to the Section Anesthesiology)
  • Article
  • Open Access
332 Views
12 Pages

29 August 2026

Background and Objectives: Gastric insufflation may occur during positive-pressure ventilation through a supraglottic airway when airway pressure exceeds the seal pressure. Because pressure-controlled ventilation (PCV) lowers peak inspiratory pressur...

(This article belongs to the Section Intensive Care/ Anesthesiology)
  • Article
  • Open Access
303 Views
15 Pages

9 September 2026

Background: Maintaining hemodynamic stability is crucial during coil embolization of unruptured intracranial aneurysms. Remimazolam has been suggested to exert less cardiovascular depression than propofol and may therefore provide more stable hemodyn...

(This article belongs to the Section Anesthesiology)
  • Article
  • Open Access
2 Citations
2,761 Views
10 Pages

Effects of Supraglottic Airway Devices on Hemodynamic Response and Optic Nerve Sheath Diameter: Proseal LMA, LMA Supreme, and I-gel LMA

  • Rahşan Dilek Okyay,
  • Gamze Küçükosman,
  • Bengü Gülhan Köksal,
  • Özcan Pişkin and
  • Hilal Ayoğlu

12 April 2023

Background and Objectives: Supraglottic airway devices (SADs) are known to be useful in eliminating the drawbacks of laryngoscopy and tracheal intubation, especially ocular pressure and stress responses. The ultrasonographic measurement of optic nerv...

(This article belongs to the Section Intensive Care/ Anesthesiology)
  • Article
  • Open Access
4 Citations
1,857 Views
10 Pages

24 January 2024

(1) Background: The physiological and pharmacological variations between men and women are known to influence drug efficacy. The objective of this study was to determine the 50% and 95% effective doses (ED50 and ED95) of remimazolam required for i-ge...

(This article belongs to the Section Anesthesiology)
  • Article
  • Open Access
1 Citations
2,289 Views
11 Pages

28 April 2024

Supraglottic airway devices such as laryngeal masks and i-gels are useful for airway management. The i-gel is a relatively new device that replaces the air-inflated cuff of the laryngeal mask with a gel-filled cuff. It remains unclear which device is...

(This article belongs to the Section Pediatric Neonatology)
  • Article
  • Open Access
56 Citations
9,488 Views
23 Pages

Rotation, Strain, and Translation Sensors Performance Tests with Active Seismic Sources

  • Felix Bernauer,
  • Kathrin Behnen,
  • Joachim Wassermann,
  • Sven Egdorf,
  • Heiner Igel,
  • Stefanie Donner,
  • Klaus Stammler,
  • Mathias Hoffmann,
  • Pascal Edme and
  • Johana Brokesova
  • + 29 authors

3 January 2021

Interest in measuring displacement gradients, such as rotation and strain, is growing in many areas of geophysical research. This results in an urgent demand for reliable and field-deployable instruments measuring these quantities. In order to furthe...

(This article belongs to the Special Issue Rotation Rate Sensors and Their Applications)
  • Study Protocol
  • Open Access
9 Citations
6,060 Views
14 Pages

The optimal airway management strategy during cardiopulmonary resuscitation is uncertain. In the case of out-of-hospital cardiac arrest, a high chest compression fraction is paramount to obtain the return of spontaneous circulation and improve surviv...

(This article belongs to the Special Issue Urgent and Acute Prehospital Care)
  • Article
  • Open Access
9 Citations
5,516 Views
13 Pages

Effect of Early Supraglottic Airway Device Insertion on Chest Compression Fraction during Simulated Out-of-Hospital Cardiac Arrest: Randomised Controlled Trial

  • Loric Stuby,
  • Laurent Jampen,
  • Julien Sierro,
  • Maxime Bergeron,
  • Erik Paus,
  • Thierry Spichiger,
  • Laurent Suppan and
  • David Thurre

31 December 2021

Early insertion of a supraglottic airway (SGA) device could improve chest compression fraction by allowing providers to perform continuous chest compressions or by shortening the interruptions needed to deliver ventilations. SGA devices do not requir...

(This article belongs to the Collection “Italian Resuscitation Council” on Resuscitation Science and Emergencies—Part I)
  • Article
  • Open Access
152 Citations
5,573 Views
18 Pages

5 October 2010

The poor bioavailability and therapeutic response exhibited by conventional ophthalmic preparations due to rapid precorneal elimination, dilution and nasolacrimal drainage of the drug may be vanquished by the use of in situ gelling systems that are...

  • Viewpoint
  • Open Access
4 Citations
2,993 Views
3 Pages

Prehospital airway devices are often classified as either basic or advanced, with this latter category including both supraglottic airway (SGA) devices and instruments designed to perform endotracheal intubation (ETI). Therefore, many authors analyze...

(This article belongs to the Section Prehospital Care)
  • Article
  • Open Access
2 Citations
20,644 Views
31 Pages

8 February 2022

Hedgehogs held a special place in ancient Egyptian life like many other desert- and marsh-dwelling animals. Their natural defensive qualities were admired by ancient Egyptians and their bodily parts, notably their hardened spines, were used as ingred...

(This article belongs to the Special Issue Animals in Ancient Material Cultures (vol. 3))
  • Study Protocol
  • Open Access
1 Citations
3,650 Views
12 Pages

12 January 2023

Most pediatric out-of-hospital cardiac arrests (OHCAs) are caused by hypoxia, which is generally consecutive to respiratory failure. To restore oxygenation, prehospital providers usually first use basic airway management techniques, i.e., bag-valve-m...

(This article belongs to the Section Pediatric Pulmonary and Sleep Medicine)
  • Article
  • Open Access
951 Views
11 Pages

Randomized Prospective Comparison of the SingularityTM Air Laryngeal Mask and Two Second-Generation Laryngeal Masks in Adult Patients

  • Danijel Novina,
  • Nadja Ettlin,
  • Norbert Nickel,
  • Norbert Aeppli,
  • JoEllen Welter and
  • Alexander Dullenkopf

30 November 2025

Background/Objectives: Supraglottic airway devices are commonly used airway management tools, with various second-generation laryngeal masks available for patients undergoing general anesthesia. These devices offer improved sealing, gastric suction c...

(This article belongs to the Section Anesthesiology)
  • Brief Report
  • Open Access
4 Citations
2,723 Views
5 Pages

There is considerable controversy regarding the optimal airway management strategy in the case of out-of-hospital cardiac arrest. Registry-based studies yield contradicting results and the actual impact of using supraglottic devices on survival and n...

(This article belongs to the Section Prehospital Care)
  • Review
  • Open Access
60 Citations
7,668 Views
32 Pages

Seismological Processing of Six Degree-of-Freedom Ground-Motion Data

  • David Sollberger,
  • Heiner Igel,
  • Cedric Schmelzbach,
  • Pascal Edme,
  • Dirk-Jan van Manen,
  • Felix Bernauer,
  • Shihao Yuan,
  • Joachim Wassermann,
  • Ulrich Schreiber and
  • Johan O. A. Robertsson

3 December 2020

Recent progress in rotational sensor technology has made it possible to directly measure rotational ground-motion induced by seismic waves. When combined with conventional inertial seismometer recordings, the new sensors allow one to locally observe...

(This article belongs to the Special Issue Rotation Rate Sensors and Their Applications)
  • Article
  • Open Access
18 Citations
3,834 Views
27 Pages

Rotaphone-CY: The Newest Rotaphone Model Design and Preliminary Results from Performance Tests with Active Seismic Sources

  • Johana Brokešová,
  • Jiří Málek,
  • Jiří Vackář,
  • Felix Bernauer,
  • Joachim Wassermann and
  • Heiner Igel

14 January 2021

Rotaphone-CY is a six-component short-period seismograph that is capable of the co-located recording of three translational (ground velocity) components along three orthogonal axes and three rotational (rotation rate) components around the three axes...

(This article belongs to the Special Issue Rotation Rate Sensors and Their Applications)
  • Review
  • Open Access
19 Citations
5,811 Views
17 Pages

Heterogeneity and Architecture of Pathological Prion Protein Assemblies: Time to Revisit the Molecular Basis of the Prion Replication Process?

  • Angélique Igel-Egalon,
  • Jan Bohl,
  • Mohammed Moudjou,
  • Laetitia Herzog,
  • Fabienne Reine,
  • Human Rezaei and
  • Vincent Béringue

10 May 2019

Prions are proteinaceous infectious agents responsible for a range of neurodegenerative diseases in animals and humans. Prion particles are assemblies formed from a misfolded, β-sheet rich, aggregation-prone isoform (PrPSc) of the host-encoded c...

(This article belongs to the Special Issue Deciphering the Molecular Targets of Prion and Prion-Like Strains)
  • Article
  • Open Access
23 Citations
5,635 Views
26 Pages

Characterization of Six-Degree-of-Freedom Sensors for Building Health Monitoring

  • Louisa Murray-Bergquist,
  • Felix Bernauer and
  • Heiner Igel

27 May 2021

Six-degree-of-freedom (6DoF) sensors measure translation along three axes and rotation around three axes. These collocated measurements make it possible to fully describe building motion without the need for an external reference point. This is an ad...

(This article belongs to the Special Issue Rotation Rate Sensors and Their Applications)
  • Article
  • Open Access
4 Citations
3,980 Views
12 Pages

Automated Quality Assessment of Interferometric Ring Laser Data

  • Andreas Brotzer,
  • Felix Bernauer,
  • Karl Ulrich Schreiber,
  • Joachim Wassermann and
  • Heiner Igel

14 May 2021

In seismology, an increased effort to observe all 12 degrees of freedom of seismic ground motion by complementing translational ground motion observations with measurements of strain and rotational motions could be witnessed in recent decades, aiming...

(This article belongs to the Special Issue Rotation Rate Sensors and Their Applications)
  • Article
  • Open Access
22 Citations
6,883 Views
13 Pages

And yet Again: Having Breakfast Is Positively Associated with Lower BMI and Healthier General Eating Behavior in Schoolchildren

  • Peggy Ober,
  • Carolin Sobek,
  • Nancy Stein,
  • Ulrike Spielau,
  • Sarah Abel,
  • Wieland Kiess,
  • Christof Meigen,
  • Tanja Poulain,
  • Ulrike Igel and
  • Mandy Vogel
  • + 1 author

18 April 2021

Given the high prevalence of childhood overweight, school-based programs aiming at nutritional behavior may be a good starting point for community-based interventions. Therefore, we investigated associations between school-related meal patterns and w...

(This article belongs to the Special Issue Community Nutrition and Food Behavior)
  • Editorial
  • Open Access
25 Citations
5,031 Views
8 Pages

Rotation Rate Sensors and Their Applications

  • Zbigniew Zembaty,
  • Felix Bernauer,
  • Heiner Igel and
  • Karl Ulrich Schreiber

7 August 2021

Measurements of rotations are unique because of their inherent property making them absolute and without an external frame of reference [...]

(This article belongs to the Special Issue Rotation Rate Sensors and Their Applications)
  • Article
  • Open Access
12 Citations
6,576 Views
17 Pages

Palm orientation reversal errors (e.g., producing the ‘bye-bye’ gesture with palm facing inward rather than outward as is customary in American culture) have been documented in the signing of deaf and hearing children with autism spectrum...

(This article belongs to the Special Issue Advances in Autism Research)
  • Letter
  • Open Access
10 Citations
3,437 Views
14 Pages

Measurements of Rotational Events Generated by Artificial Explosions and External Excitations Using the Optical Fiber Sensors Network

  • Anna T. Kurzych,
  • Leszek R. Jaroszewicz,
  • Michał Dudek,
  • Jerzy K. Kowalski,
  • Felix Bernauer,
  • Joachim Wassermann and
  • Heiner Igel

27 October 2020

Measurements of artificial events can substantially confirm the data validity of constructed rotational sensors, as well as provide methods for simplifying the measurement process. The above task, especially with international cooperation, can provid...

(This article belongs to the Special Issue Rotation Rate Sensors and Their Applications)
  • Article
  • Open Access
36 Citations
5,792 Views
14 Pages

Associations of Green Spaces and Streets in the Living Environment with Outdoor Activity, Media Use, Overweight/Obesity and Emotional Wellbeing in Children and Adolescents

  • Tanja Poulain,
  • Carolin Sobek,
  • Juliane Ludwig,
  • Ulrike Igel,
  • Gesine Grande,
  • Verena Ott,
  • Wieland Kiess,
  • Antje Körner and
  • Mandy Vogel

Aspects of the living environment can affect health and wellbeing of children and adolescents. Whereas most previous studies assessed the more distant residential urban environment, less is known on possible effects of the close environment. The pres...

(This article belongs to the Section Children's Health)
  • Article
  • Open Access
6 Citations
4,864 Views
20 Pages

Prediction of Drug–Drug–Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling

  • Christina Kovar,
  • Lukas Kovar,
  • Simeon Rüdesheim,
  • Dominik Selzer,
  • Boian Ganchev,
  • Patrick Kröner,
  • Svitlana Igel,
  • Reinhold Kerb,
  • Elke Schaeffeler and
  • Thorsten Lehr
  • + 2 authors

Clomiphene, a selective estrogen receptor modulator (SERM), has been used for the treatment of anovulation for more than 50 years. However, since (E)-clomiphene ((E)-Clom) and its metabolites are eliminated primarily via Cytochrome P450 (CYP) 2D6 and...

(This article belongs to the Special Issue Advances in Pharmacokinetics, Pharmacodynamics and Drug Interactions)
  • Article
  • Open Access
9 Citations
4,997 Views
15 Pages

Purchasing Behavior, Setting, Pricing, Family: Determinants of School Lunch Participation

  • Carolin Sobek,
  • Peggy Ober,
  • Sarah Abel,
  • Ulrike Spielau,
  • Wieland Kiess,
  • Christof Meigen,
  • Tanja Poulain,
  • Ulrike Igel,
  • Mandy Vogel and
  • Tobias Lipek

24 November 2021

Despite growing school lunch availability in Germany, its utilization is still low, and students resort to unhealthy alternatives. We investigated predictors of school lunch participation and reasons for nonparticipation in 1215 schoolchildren. Child...

(This article belongs to the Section Nutritional Policies and Education for Health Promotion)
  • Feature Paper
  • Review
  • Open Access
34 Citations
11,512 Views
29 Pages

Prion Strains and Transmission Barrier Phenomena

  • Angélique Igel-Egalon,
  • Vincent Béringue,
  • Human Rezaei and
  • Pierre Sibille

Several experimental evidences show that prions are non-conventional pathogens, which physical support consists only in proteins. This finding raised questions regarding the observed prion strain-to-strain variations and the species barrier that happ...

(This article belongs to the Special Issue PrPSc prions: state of the art)
  • Article
  • Open Access
3 Citations
5,169 Views
19 Pages

26 July 2018

The tropical, oceanic mean relationship between column relative humidity and precipitation is highly non-linear. Mean precipitation remains weak until it rapidly picks up and grows at high column humidity. To investigate the origin of this relationsh...

(This article belongs to the Special Issue Precipitation: Measurement and Modeling)
  • Review
  • Open Access
9 Citations
4,465 Views
9 Pages

High-Pressure Response of Amyloid Folds

  • Joan Torrent,
  • Davy Martin,
  • Angélique Igel-Egalon,
  • Vincent Béringue and
  • Human Rezaei

28 February 2019

The abnormal protein aggregates in progressive neurodegenerative disorders, such as Alzheimer’s, Parkinson’s and prion diseases, adopt a generic structural form called amyloid fibrils. The precise amyloid fold can differ between patients...

(This article belongs to the Special Issue Deciphering the Molecular Targets of Prion and Prion-Like Strains)
  • Article
  • Open Access
6 Citations
3,125 Views
19 Pages

13 December 2024

Gadolinium zirconate (Gd2Zr2O7, GZO) has been investigated for two decades as a thermal barrier coating (TBC) material in gas turbines. The advantages of this material over conventional yttria-stabilized zirconia (YSZ) are its lower thermal conductiv...

(This article belongs to the Special Issue Smart Coatings)
  • Article
  • Open Access
6 Citations
3,073 Views
12 Pages

26 June 2024

Oxidation of the bond coat during turbine operation leads to additional stresses in the thermal barrier coating (TBC) system that promotes spalling of the thermal insulation. Therefore, the oxidation behavior of a TBC system plays an important role i...

(This article belongs to the Section High-Energy Beam Surface Engineering and Coatings)
  • Article
  • Open Access
33 Citations
6,031 Views
22 Pages

Above-Ground Biomass Prediction for Croplands at a Sub-Meter Resolution Using UAV–LiDAR and Machine Learning Methods

  • Jaime C. Revenga,
  • Katerina Trepekli,
  • Stefan Oehmcke,
  • Rasmus Jensen,
  • Lei Li,
  • Christian Igel,
  • Fabian Cristian Gieseke and
  • Thomas Friborg

12 August 2022

Current endeavors to enhance the accuracy of in situ above-ground biomass (AGB) prediction for croplands rely on close-range monitoring surveys that use unstaffed aerial vehicles (UAVs) and mounted sensors. In precision agriculture, light detection a...

(This article belongs to the Section AI Remote Sensing)
  • Article
  • Open Access
13 Citations
6,027 Views
20 Pages

Physiologically Based Pharmacokinetic Modeling to Describe the CYP2D6 Activity Score-Dependent Metabolism of Paroxetine, Atomoxetine and Risperidone

  • Simeon Rüdesheim,
  • Dominik Selzer,
  • Thomas Mürdter,
  • Svitlana Igel,
  • Reinhold Kerb,
  • Matthias Schwab and
  • Thorsten Lehr

The cytochrome P450 2D6 (CYP2D6) genotype is the single most important determinant of CYP2D6 activity as well as interindividual and interpopulation variability in CYP2D6 activity. Here, the CYP2D6 activity score provides an established tool to categ...

(This article belongs to the Section Clinical Pharmaceutics)
  • Article
  • Open Access
14 Citations
6,009 Views
19 Pages

Actigraphy-Derived Sleep Profiles of Children with and without Attention-Deficit/Hyperactivity Disorder (ADHD) over Two Weeks—Comparison, Precursor Symptoms, and the Chronotype

  • Mirjam Ziegler,
  • Anna Kaiser,
  • Christine Igel,
  • Julia Geissler,
  • Konstantin Mechler,
  • Nathalie E. Holz,
  • Katja Becker,
  • Manfred Döpfner,
  • Marcel Romanos and
  • Tobias Banaschewski
  • + 3 authors

27 November 2021

Although sleep problems are common in children with ADHD, their extent, preceding risk factors, and the association between neurocognitive performance and neurobiological processes in sleep and ADHD, are still largely unknown. We examined sleep varia...

(This article belongs to the Special Issue Advances in Sleep and ADHD)
  • Article
  • Open Access
1 Citations
1,401 Views
18 Pages

Wave-Screening Methods for Prestress-Loss Assessment of a Large-Scale Post-Tensioned Concrete Bridge Model Under Outdoor Conditions

  • Chun-Man Liao,
  • Felix Bernauer,
  • Ernst Niederleithinger,
  • Heiner Igel and
  • Céline Hadziioannou

27 May 2025

This paper presents advancements in structural health monitoring (SHM) techniques, with a particular focus on wave-screening methods for assessing prestress loss in a large-scale prestressed concrete (PC) bridge model under outdoor conditions. The wa...

(This article belongs to the Section Civil Engineering)
  • Article
  • Open Access
496 Views
17 Pages

Background: Manual bag-valve ventilation is a fundamental intervention in prehospital and emergency care but remains highly operator-related and frequently associated with inappropriate tidal volume delivery. Excessive or insufficient ventilation may...

(This article belongs to the Special Issue IoT Technology in Bioengineering Applications: Third Edition)
  • Article
  • Open Access
1 Citations
2,801 Views
12 Pages

Introduction: Supraglottic airway devices play an important role in airway management in both pre-hospital as well as in-hospital settings. They are a well-recognised alternative to definitive airways in current medical practice. However, despite the...

(This article belongs to the Special Issue New Developments in Endotracheal Intubation and Airway Management)
  • Article
  • Open Access
11 Citations
3,304 Views
19 Pages

Evaluation of Bone Turnover around Short Finned Implants in Atrophic Posterior Maxilla: A Finite Element Study

  • Andrii Kondratiev,
  • Vladislav Demenko,
  • Igor Linetskiy,
  • Hans-Werner Weisskircher and
  • Larysa Linetska

24 September 2024

Background/Objectives: Dental implants have emerged as a modern solution for edentulous jaws, showing high success rates. However, the implant’s success often hinges on the patient’s bone quality and quantity, leading to higher failure ra...

(This article belongs to the Special Issue Advancements in Prosthodontics: Exploring Innovations in Rehabilitation Medicine)