Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (137)

Search Parameters:
Keywords = FSFI

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
14 pages, 345 KB  
Article
Exploring the Diagnostic and Therapeutic Pathways of Women with Dyspareunia: A Mixed-Methods Study
by Joanna Wojtas, Zofia Sotomska, Marek Murawski and Magdalena Emilia Grzybowska
J. Clin. Med. 2026, 15(2), 787; https://doi.org/10.3390/jcm15020787 - 19 Jan 2026
Viewed by 170
Abstract
Background/Objectives: This study explores the diagnostic and management pathways for dyspareunia in women seeking specialist care, focusing on gynecologists’ feedback and women’s perceptions of their experience. Methods: An online survey was conducted among 225 sexually active women to explore their perceptions [...] Read more.
Background/Objectives: This study explores the diagnostic and management pathways for dyspareunia in women seeking specialist care, focusing on gynecologists’ feedback and women’s perceptions of their experience. Methods: An online survey was conducted among 225 sexually active women to explore their perceptions of dyspareunia, its impact on relationships, and experiences with healthcare feedback, diagnosis, and treatment. The Numeric Rating Scale (NRS) for pain assessment and the Female Sexual Function Index (FSFI) were used. Gynecologists’ feedback was classified as positive, neutral, or negative based on its influence on the therapeutic pathway. Results: Of 78 women reporting dyspareunia, 12 with pain level ≥5 on NRS were selected for in-depth analysis. The mean pain score was 7.0 ± 1.53, with symptoms lasting from several months to over two years and occurring during most sexual encounters. The mean FSFI score was 24.86 ± 4.54, with half of the participants scoring within the sexual dysfunction range. Qualitative findings revealed frequent dismissive responses from healthcare professionals and limited access to appropriate management. Common self-management strategies included changing sexual positions and using lubricants, while half of the participants had not undergone a formal diagnostic process. Most frequent diagnoses were hormonal disorders and recurrent genital tract infections, and women were advised to undergo pharmacological treatment. Half of the participants were unaware of the possibility of physiotherapeutic management. Conclusions: Women with dyspareunia often face an inadequate diagnostic and therapeutic process. The care received is often insufficient and not aligned with a biopsychosocial model. Full article
(This article belongs to the Special Issue Current Trends in Urogynecology: 3rd Edition)
Show Figures

Figure 1

13 pages, 881 KB  
Article
Sleep Matters for Intimacy: Impact of Sleep Quality and Psychosocial Context on Female Sexual Function During Pregnancy
by Razvan-Ionut Daniluc, Iulia Georgiana Bogdan, Alina Tischer, Marius Craina and Loredana Gabriela Stana
Medicina 2026, 62(1), 150; https://doi.org/10.3390/medicina62010150 - 12 Jan 2026
Viewed by 221
Abstract
Background and Objectives: Sleep disruption and reduced physical activity are common in pregnancy and may impair sexual function through mood, body-image, and relational pathways. We prospectively examined whether sleep quality and physical activity predicted third-trimester sexual function in a Romanian antenatal cohort, [...] Read more.
Background and Objectives: Sleep disruption and reduced physical activity are common in pregnancy and may impair sexual function through mood, body-image, and relational pathways. We prospectively examined whether sleep quality and physical activity predicted third-trimester sexual function in a Romanian antenatal cohort, and explored psychosocial correlates. Materials and Methods: In a single-center cohort, 102 pregnant adults were enrolled ≤ 20 weeks and followed to the third trimester. Sleep (Pittsburgh Sleep Quality Index, PSQI), sexual function (Female Sexual Function Index–Romanian version, FSFI-RO), physical activity (IPAQ-SF), depressive symptoms (PHQ-9), body-image avoidance (Body Exposure during Sexual Activities Questionnaire, BESAQ), and perceived social support (MSPSS) were assessed. Groups were defined by mid-/late-pregnancy sleep (good, PSQI ≤ 5; poor, PSQI > 5). Analyses used t-tests, Pearson correlations, multivariable linear regression for FSFI-Total, and logistic regression for FSFI-Total < 26.55. Results: Compared with good sleepers (n = 56), women with poor sleep (n = 46) had lower third-trimester FSFI-Total (24.4 ± 3.9 vs. 27.9 ± 4.3; p < 0.001) and higher odds of FSFI-defined dysfunction (adjusted OR 121.1; 95% CI 19.2–763.0; p < 0.001). FSFI-Total correlated with worse sleep (PSQI r = −0.42), depressive symptoms (PHQ-9 r = −0.36), social support (MSPSS r = 0.40), body-image avoidance (BESAQ r = −0.34) and physical activity (IPAQ-SF r = 0.24; all p ≤ 0.015). In adjusted models (R2 = 0.42), higher MSPSS (β = 0.26; p = 0.004) was protective, whereas PSQI (β = −0.24; p = 0.008), ΔPHQ-9 (β = −0.19; p = 0.023), BESAQ (β = −0.17; p = 0.031), and higher BMI (β = −0.14; p = 0.049) predicted lower FSFI-Total. Conclusions: In this antenatal cohort, poor sleep was strongly and independently associated with lower sexual function, with meaningful contributions from social support, mood, body-image cognition, and physical activity, highlighting sleep as a clinically actionable target for preserving sexual well-being in pregnancy. Full article
(This article belongs to the Section Obstetrics and Gynecology)
Show Figures

Figure 1

15 pages, 332 KB  
Article
Attachment Styles and Sexual Function Among Survivors of Autologous Hematopoietic Stem Cell Transplantation: A Multicenter Study
by Ioanna Tsatsou, Theocharis I. Konstantinidis, Kyriaki Mystakidou, Maria Nikoloudi, Eleni Panagou, Paraskevi-Maria Prapa, Maria Angelaki, Dimitra Bartzi and Ourania Govina
Medicina 2026, 62(1), 38; https://doi.org/10.3390/medicina62010038 - 24 Dec 2025
Viewed by 479
Abstract
Background and Objectives: Autologous hematopoietic stem cell transplantation (AHSCT) offers life-saving treatment for hematologic malignancies but can result in persistent sexual dysfunction and relationship challenges. Attachment theory provides a valuable framework for understanding how enduring relational patterns influence sexual well-being. This study [...] Read more.
Background and Objectives: Autologous hematopoietic stem cell transplantation (AHSCT) offers life-saving treatment for hematologic malignancies but can result in persistent sexual dysfunction and relationship challenges. Attachment theory provides a valuable framework for understanding how enduring relational patterns influence sexual well-being. This study aimed to assess sexual function and attachment styles in AHSCT survivors and examine correlations between attachment and sexual health outcomes. Materials and Methods: A multicenter, cross-sectional study was conducted from December 2019 to March 2022 in five public hospitals in Athens, Greece. Participants were 127 adult survivors who had undergone AHSCT between 6 months and 5 years before enrollment. Sexual function was evaluated with the International Index of Erectile Function (IIEF) for men and the Female Sexual Function Index (FSFI) for women. Attachment style was measured using the Experience in Close Relationships Scale–Short Form (ECRSHORT-FORMSCALE). Results: Men demonstrated high erectile function (IIEF total: 54.10 ± 20.1), whereas women reported moderate sexual dysfunction (FSFI total: 22.51 ± 8.95). Both genders showed average attachment levels, with anxiety scoring lowest and discomfort with closeness highest. Between-group comparisons revealed no significant difference in anxiety (p = 0.95), a near-significant difference in avoidance (p = 0.056), and a significant difference in discomfort with closeness (p < 0.0001), with women scoring higher. In men, no significant correlations emerged between attachment and sexual function. In women, higher attachment anxiety correlated negatively with all FSFI domains except pain, avoidance correlated positively with lubrication, and discomfort with closeness correlated negatively with desire and pain. Conclusions: Findings reveal gender-specific patterns in attachment and their influence on sexual function of AHSCT survivors, highlighting the need for attachment-informed interventions to support intimacy, relationship satisfaction, and overall quality of life in survivorship care. Full article
11 pages, 3358 KB  
Article
The Effect of Technique Selection in Labiaplasty Surgery: Analysis of Aesthetic and Functional Outcomes
by Elif Ucar, Melih Bestel, Burak Huseyin Ucar and Ozan Dogan
J. Clin. Med. 2025, 14(24), 8923; https://doi.org/10.3390/jcm14248923 - 17 Dec 2025
Viewed by 510
Abstract
Background/Objectives: This study aimed to compare the effects of two different labiaplasty techniques, trim resection and modified wedge resection, on postoperative patient comfort, complication rates, and sexual function. Methods: Between 2021 and 2025, female patients who underwent labiaplasty using two different [...] Read more.
Background/Objectives: This study aimed to compare the effects of two different labiaplasty techniques, trim resection and modified wedge resection, on postoperative patient comfort, complication rates, and sexual function. Methods: Between 2021 and 2025, female patients who underwent labiaplasty using two different techniques at a tertiary care centre were retrospectively evaluated. The patients were divided into two equal groups: Group 1 underwent wedge resection, and Group 2 underwent trim resection. Postoperative outcomes were assessed at the first week, first month, and sixth month. Sexual and aesthetic outcomes were evaluated using the Female Sexual Function Index (FSFI) and the Female Genital Self-Image Scale (FGSIS). Results: A total of 40 female patients were included in the study. A statistically significant postoperative increase was observed in the total FGSIS and FSFI scores in both groups (p < 0.001 for all comparisons). Trim resection resulted in greater improvement in aesthetic satisfaction and body image, as reflected by higher postoperative FGSIS scores. In contrast, wedge resection produced more pronounced improvements in sexual function, particularly in the FSFI subdomains of arousal, orgasm, and satisfaction. Notably, the three patients who developed suture dehiscence at the first postoperative week had all undergone wedge resection and were active smokers. Conclusions: Both surgical techniques were effective in enhancing aesthetic satisfaction and sexual function following labiaplasty. While the trim technique appeared superior in improving aesthetic outcomes, the wedge technique provided greater benefits in specific sexual function parameters. Full article
Show Figures

Figure 1

16 pages, 253 KB  
Article
Factors Influencing the Quality of Women’s Sexual Life: A Study of Polish Female Students
by Maciej Stokłosa, Iga Florczyk, Gniewko Więckiewicz, Karolina Kiersten, Magdalena Piegza and Robert Pudlo
Healthcare 2025, 13(24), 3278; https://doi.org/10.3390/healthcare13243278 - 13 Dec 2025
Viewed by 1281
Abstract
Background/Objectives: Women’s sexual quality of life is a multidimensional construct shaped by individual, psychological, relational, and health-related factors. This exploratory cross-sectional study aimed to identify selected determinants of sexual functioning in young women, with a particular focus on partner relationships and sexual dysfunction [...] Read more.
Background/Objectives: Women’s sexual quality of life is a multidimensional construct shaped by individual, psychological, relational, and health-related factors. This exploratory cross-sectional study aimed to identify selected determinants of sexual functioning in young women, with a particular focus on partner relationships and sexual dysfunction symptoms within the couple. Methods: Data from 199 female university students aged 18–30 years, recruited via Facebook, were analyzed. Participants completed the Female Sexual Function Index (FSFI) and an author-designed questionnaire assessing sociodemographic variables, relationship characteristics, and self-perceived sexual difficulties in themselves and their partners. Descriptive statistics, bivariate analyses, and multivariable linear regression models were used to examine factors associated with the FSFI total and domain scores. Results: In this self-selected, non-representative sample, over 75% of women reported at least one self-perceived sexual difficulty, while 35.2% obtained FSFI scores at or below the established cutoff, indicating an increased risk of female sexual dysfunction rather than a confirmed diagnosis. In multivariable analysis, higher intercourse frequency, greater overall sexual satisfaction in the last 12 months, and fewer self-reported dysfunction symptoms emerged as the strongest independent predictors of higher FSFI total scores. Women who perceived premature ejaculation in their male partners tended to report lower orgasm and satisfaction domain scores, although this perception was not independently associated with the FSFI total score after adjustment for individual and relationship factors. Conclusions: These findings underline the role of both individual and relational factors in young women’s sexual functioning and support a holistic, couple-centred perspective in sexual health assessment. Full article
15 pages, 667 KB  
Article
Multivariate Profiles of Female Sexual Function: A Cluster Analysis of FSFI Domains in Women with and Without PCOS
by Andrei Daescu, Ana-Maria Cristina Daescu, Liana Dehelean, Dan-Bogdan Navolan, Alexandru-Ioan Gaitoane and Dana Stoian
Biomedicines 2025, 13(12), 3069; https://doi.org/10.3390/biomedicines13123069 - 12 Dec 2025
Viewed by 627
Abstract
Background/Objectives: Female sexual dysfunction (FSD) is common in PCOS, yet mean group comparisons can mask variability at the individual level. We aimed to identify and characterize person-centered profiles of sexual function from the six FSFI (Female Sexual Function Index) domains, and secondarily to [...] Read more.
Background/Objectives: Female sexual dysfunction (FSD) is common in PCOS, yet mean group comparisons can mask variability at the individual level. We aimed to identify and characterize person-centered profiles of sexual function from the six FSFI (Female Sexual Function Index) domains, and secondarily to describe the distribution of PCOS across profiles. Methods: In an age- and anthropometry-matched case–control sample, unsupervised clustering on FSFI domains was performed; clinical and psychosocial correlates were compared, and logistic regression tested prediction of FSFI-defined FSD. Results: Two profiles emerged—Sexual Dysfunction vs. Preserved Function—with clear multivariate separation. Dysfunction showed lower FSFI, higher adiposity, and worse body-image discomfort. PCOS was more frequent in Dysfunction but not significantly. Cluster membership predicted FSD. Conclusions: Person-centered profiling reveals clinically meaningful heterogeneity that transcends diagnosis and highlights adiposity and body-image distress as salient, potentially modifiable correlates. Full article
(This article belongs to the Special Issue Ovarian Physiology and Reproduction)
Show Figures

Figure 1

16 pages, 925 KB  
Systematic Review
Chair-Based Magnetic Pelvic Floor Stimulation and Female Sexual Function in Women with Urinary Incontinence: A Systematic Review
by Geanina Sacarin, Marius Craina, Bogdan Sorop, Mihai Calin Bica, Lavinia Stelea, Mihaela Prodan, Madalina Sorop, Alina Simona Abu-Awwad, Maria Sorop-Florea, Adina Ruta and Razvan Nitu
J. Clin. Med. 2025, 14(23), 8496; https://doi.org/10.3390/jcm14238496 - 30 Nov 2025
Viewed by 1672
Abstract
Background and objectives: Urinary incontinence (UI) frequently coexists with female sexual dysfunction (FSD). Magnetic chair therapies—high-intensity focused electromagnetic stimulation (HIFEM) and extracorporeal magnetic innervation (ExMI)—are increasingly used for UI, but sexual outcomes are less well synthesized. We reviewed open-access clinical studies reporting [...] Read more.
Background and objectives: Urinary incontinence (UI) frequently coexists with female sexual dysfunction (FSD). Magnetic chair therapies—high-intensity focused electromagnetic stimulation (HIFEM) and extracorporeal magnetic innervation (ExMI)—are increasingly used for UI, but sexual outcomes are less well synthesized. We reviewed open-access clinical studies reporting Female Sexual Function Index (FSFI) and/or Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ) outcomes. Methods: Following PRISMA 2020 and an OSF-registered protocol, we searched PubMed, Scopus, and Web of Science to 25 October 2025. Eligible studies enrolled adult women with UI, used chair-based magnetic stimulation, and reported FSFI and/or PISQ before and after treatment. Data were narratively synthesized. Results: Five studies (n ≈ 219; FSFI n ≈ 170; PISQ n = 49) met the criteria. Randomized and controlled data showed clinically relevant advantages for active therapy: FSFI between-group gains were +6.3 at 8 weeks for HIFEM+PFMT vs. PFMT and +5.63 at 14 weeks for pulsed magnetic stimulation vs. sham. Single-arm cohorts reported FSFI increases of +8.1 at 3 months and +9.4 to +10.0 by ~6–12 months. PISQ-12 improved by +3.86 at 12 weeks when magnetic stimulation was combined with optimized PFMT. UI severity also decreased (ICIQ-UI SF −9.85; 74.4% at 12 weeks; ~71–72% reduction at 9–12 months). Adverse events were uncommon and mild where reported. Conclusions: Across heterogeneous designs, chair-based magnetic stimulation is associated with meaningful improvements in sexual function and continence in women with UI, with signals that combining stimulation with PFMT may enhance benefits. Standardized, longer-term trials centered on FSFI/PISQ are warranted. Full article
(This article belongs to the Section Obstetrics & Gynecology)
Show Figures

Figure 1

14 pages, 510 KB  
Article
Linking Thyroid Function, Morphology, Autoimmunity, Body Mass Index, and Reproductive Aging to Women’s Sexual Health: Evidence from a Population Study in Kaunas
by Dalia Daukšienė, Raimonda Klimaitė, Aistė Kondrotienė, Radvilė Matukaitienė, Jonas Čeponis, Agnė Rimkutė, Laura Dudonytė, Rasa Steponavičiūtė, Dalia Lukšienė, Vaiva Lesauskaitė, Džilda Veličkienė, Rasa Verkauskienė and Birutė Žilaitienė
J. Clin. Med. 2025, 14(23), 8441; https://doi.org/10.3390/jcm14238441 - 28 Nov 2025
Viewed by 494
Abstract
Background/Objectives: While it is known that Hashimoto’s thyroiditis (HT), goiter, thyroid nodules, and thyroid dysfunction may affect women’s reproductive health through hormonal and metabolic mechanisms, data are limited regarding the specific impacts on female sexual function. This study evaluated sexual function in women [...] Read more.
Background/Objectives: While it is known that Hashimoto’s thyroiditis (HT), goiter, thyroid nodules, and thyroid dysfunction may affect women’s reproductive health through hormonal and metabolic mechanisms, data are limited regarding the specific impacts on female sexual function. This study evaluated sexual function in women with thyroid disorders and examined its associations with thyroid function, age, menopausal status, and body mass index (BMI). Methods: A population-based survey was conducted in Kaunas, Lithuania, within the WHO MONICA framework. A random sample of 1569 women aged 25–69 years was included in the final analysis after applying the exclusion criteria. Anthropometric measurements were taken using standardized procedures, and the BMI was calculated. Sexual function was assessed using the 19-item Female Sexual Function Index (FSFI). Thyroid structure was evaluated by a team of trained physicians using ultrasound, while thyroid function was assessed via serum analysis (ELISA-based assays for TSH, fT4, and anti-TPO antibodies). Results: Of the 1569 women analyzed, 64.1% had sexual dysfunction (SD) (FSFI ≤ 26.55). Age and BMI showed significant negative correlations with all FSFI domains, with the strongest associations for arousal, lubrication, and total FSFI score (p < 0.01). SD was more prevalent among postmenopausal (43.6%) women than in premenopausal women (22.6%, p < 0.001) and increased with a higher BMI (p < 0.001). HT was found in 28.3% of participants. Compared with the reference group, women with HT were older, had higher BMI, higher TSH levels, and more hypothyroidism (p < 0.001). SD was more common in the HT group (71.7% vs. 64.2%, p < 0.001), with significantly lower lubrication and higher pain scores. In the multivariate analysis, only goiter remained an independent predictor of SD (p = 0.04). Conclusions: In conclusion, women with HT were older; had a higher BMI; and more frequently experienced SD, particularly reduced lubrication and increased pain, compared with the reference group. Although several thyroid conditions were associated with sexual dysfunction, only goiter remained an independent predictor after adjusting for age and BMI. Full article
(This article belongs to the Section Endocrinology & Metabolism)
Show Figures

Figure 1

17 pages, 705 KB  
Article
The Hidden Burden of Sexual Dysfunction and Healthcare Service Gaps in Tunisian Spinal Cord Patients: A Cross-Sectional Study
by Ines Loubiri, Ismail Dergaa, Habib Hajji, Halil İbrahim Ceylan, Mariem Gaddour, Nourhene Dridi, Hela Ghali, Valentina Stefanica and Sonia Jemni
J. Clin. Med. 2025, 14(23), 8380; https://doi.org/10.3390/jcm14238380 - 26 Nov 2025
Viewed by 669
Abstract
Background/Objectives: Spinal cord injury represents a devastating neurological condition affecting approximately 27 million individuals globally, with particularly severe impacts on sexual function. Sexual dysfunction in SCI patients is multifactorial, with prevalence rates reaching 80–90% across different populations. In low- and middle-income countries, [...] Read more.
Background/Objectives: Spinal cord injury represents a devastating neurological condition affecting approximately 27 million individuals globally, with particularly severe impacts on sexual function. Sexual dysfunction in SCI patients is multifactorial, with prevalence rates reaching 80–90% across different populations. In low- and middle-income countries, sexual health remains critically neglected in rehabilitation settings due to cultural barriers, inadequate healthcare infrastructure, and limited clinician training. Tunisia, with an estimated 31,000 SCI cases, lacks comprehensive data on sexual dysfunction prevalence and healthcare communication patterns in this vulnerable population. Based on identified research gaps, our study aimed to (i) assess the prevalence and severity of sexual dysfunction among Tunisian SCI patients using validated assessment tools, (ii) identify clinical and demographic factors associated with sexual dysfunction, and (iii) evaluate the current state of sexual health communication and rehabilitation services. Methods: A cross-sectional observational study was conducted at Sahloul University Hospital, Sousse, Tunisia, between July and September 2025. Fifty-one adults with chronic SCI (≥12 months post-injury) were recruited through consecutive sampling. Sexual function was assessed using the International Index of Erectile Function (IIEF) for men and the Female Sexual Function Index (FSFI) for women. Additional assessments included demographic data, injury characteristics using the American Spinal Injury Association Impairment Scale, pain evaluation, functional status, psychological well-being, and sleep quality. Statistical analysis included descriptive statistics, Spearman correlations, and significance testing (p < 0.05). Results: Sexual dysfunction affected 84.3% of participants (43/51), with 88.5% of men experiencing moderate-to-severe erectile dysfunction (median IIEF: 12 [7–36.25]) and 80% of women reporting sexual dysfunction (median FSFI: 7.2 [4–24.25]). Severe dysfunction (FSFI ≤ 10) was present in 56% of female participants. Sexual dysfunction correlated significantly with urinary incontinence (p = 0.045) and with measures of functional independence, including SCIM-III (ρ = 0.466, p = 0.016) and FIM (ρ = 0.569, p = 0.002) among men, and SCIM-III (ρ = 0.469, p = 0.018) and FIM (ρ = 0.495, p = 0.012) among women, indicating moderate positive associations between sexual and functional outcomes. Only 11.5% of men achieved normal erectile function (IIEF ≥48). Psychological factors (HAD-S) and pain scores (NRS, DN4) were not significantly associated with sexual function. A total of 92% of patients reported never discussing sexual health with their healthcare providers, and 100% lacked access to dedicated sexual rehabilitation services, underscoring severe care and communication gaps in the Tunisian SCI rehabilitation system. Conclusions: Sexual dysfunction is highly prevalent among Tunisian spinal cord injury patients and is closely associated with reduced functional independence and urinary issues. Despite its significant impact, sexual health remains largely neglected in rehabilitation care. These findings highlight an urgent need to integrate sexual health into national rehabilitation protocols through provider training, multidisciplinary services, and culturally sensitive education. Systematic sexual health assessment and rehabilitation should be considered essential to improving the quality of life and restoring dignity for affected individuals. Full article
(This article belongs to the Section Clinical Rehabilitation)
Show Figures

Figure 1

15 pages, 1123 KB  
Systematic Review
Relationship Satisfaction and Body Image-Related Quality of Life as Correlates of Sexual Function During Pregnancy: A Systematic Review
by Razvan-Ionut Daniluc, Marius Craina, Alina Andreea Tischer, Andrei-Cristian Bondar, Lavinia Stelea, Mihai Calin Bica and Loredana Stana
Healthcare 2025, 13(23), 3020; https://doi.org/10.3390/healthcare13233020 - 22 Nov 2025
Viewed by 832
Abstract
Background and Objectives: Sexual function often fluctuates during pregnancy, yet the contributions of body image-related quality of life (BI-QoL)—operationalized via body image instruments such as the Body Exposure during Sexual Activities Questionnaire (BESAQ) and pregnancy-specific body image scales—and relationship satisfaction remain inconsistently quantified. [...] Read more.
Background and Objectives: Sexual function often fluctuates during pregnancy, yet the contributions of body image-related quality of life (BI-QoL)—operationalized via body image instruments such as the Body Exposure during Sexual Activities Questionnaire (BESAQ) and pregnancy-specific body image scales—and relationship satisfaction remain inconsistently quantified. This systematic review aimed to synthesize evidence on the associations between BI-QoL, relationship satisfaction, and female sexual function in pregnant women. Methods: Following PRISMA 2020, PubMed/MEDLINE, Scopus, and Web of Science were searched up to 23 August 2025. Eligible studies enrolled pregnant women and reported quantitative data on BI-QoL and/or relationship satisfaction alongside sexual outcomes. Risk-of-bias used design-appropriate tools; findings were narratively synthesized due to heterogeneity. Results: Thirteen studies met criteria (predominantly cross-sectional; sample sizes 107–472; one RCT; several couples/longitudinal cohorts). Female Sexual Function Index (FSFI) means clustered in the mid-20s; in a randomized trial, the intervention arm improved FSFI by +1.76 points (22.95 → 24.71; p = 0.002). Overall female sexual dysfunction reached 54.7% in the largest cross-sectional sample. Higher body exposure anxiety was associated with ~4.24-fold greater odds of dysfunction across trimesters. Marital satisfaction explained ≈36% of FSFI variance in multivariable models. Pregnancy context factors related to BI-QoL included planned pregnancy (β = −0.273) and third trimester (β = −0.280) indicating better BI-QoL, while more children predicted worse BI-QoL (β = +0.317). In one cohort, BI during sexual activity worsened postpartum versus pregnancy (p = 0.01). Conclusions: Across diverse settings, poorer BI-QoL and lower relationship satisfaction were consistently linked to reduced sexual function during pregnancy, with desire/arousal most affected. Routine screening and couple-sensitive counseling should be considered as promising, yet still under-tested, strategies that warrant further evaluation in intervention studies. Full article
Show Figures

Figure 1

10 pages, 290 KB  
Article
Feasibility of Multimodal Energy-Based Therapy for Pelvic Floor Disorders
by Yoav Baruch, Clarissa Costa, Marta Barba, Alice Cola and Matteo Frigerio
Medicina 2025, 61(12), 2078; https://doi.org/10.3390/medicina61122078 - 21 Nov 2025
Viewed by 716
Abstract
Background and Objectives: Pelvic floor disorders are highly prevalent among women globally and can severely compromise daily functioning and well-being. Emerging energy-based modalities have reshaped conservative management strategies, by allowing individualized therapeutic approaches. The aim of this study was to evaluate the [...] Read more.
Background and Objectives: Pelvic floor disorders are highly prevalent among women globally and can severely compromise daily functioning and well-being. Emerging energy-based modalities have reshaped conservative management strategies, by allowing individualized therapeutic approaches. The aim of this study was to evaluate the utility of customized energy-based applications, via an innovative multimodal EVA/DAFNE device that incorporates multimodal energy-based synergistic technologies for the treatment of pelvic floor dysfunction. Materials and Methods: Patients with PFDs (pelvic organ prolapse, all types of urinary incontinence, bladder voiding dysfunction, and dyspareunia) who selected conservative treatments were prospectively enrolled. Baseline and after-treatment quality of life was assessed using the following validated tools: Urinary Distress Inventory-6 (UDI-6), Pelvic Organ Prolapse Distress Inventory-6 (POPDI-6), Female Sexual Function Index-6 (FSFI-6), Marinoff Scale, 0-100 VAS, and Vaginal Health Index. Overall improvement was measured through the Patient Global Impression of Improvement (PGI-I). Three to five sessions of treatment tailored according to the patient’s symptoms and clinical findings were delivered. Data were analyzed using standard statistical methods. Results: Twenty-six women with PFD who desired energy-based conservative treatment were recruited. Mean age was 48.6 ± 16.7 years. Indications for treatment were dyspareunia (n = 10; 38.5%), stress urinary incontinence (n = 9; 34.6%), mild pelvic organ prolapse (n = 6; 23.1%), genitourinary syndrome of menopause (n = 5; 19.2%), voiding dysfunction (n = 4; 15.4%), and overactive bladder syndrome (n = 2; 7.7%). Mean number of treatments was four. Baseline and after-treatment quality-of-life scores differed significantly. According to PGI-I scores 88.5% of patients considered themselves improved. Conclusions: Our study provides pilot estimates as to the safety and efficacy of a multimodal integrated treatment protocol for the treatment of PFD. Integrating multimodal energy-based conservative therapy into tailored treatment protocols can prove efficient and useful. Full article
(This article belongs to the Section Obstetrics and Gynecology)
15 pages, 1226 KB  
Systematic Review
Determinants of Postpartum Sexual Dysfunction in the First Year: A Systematic Review
by Aris Boarta, Adrian Gluhovschi, Marius Lucian Craina, Carmen Ioana Marta, Bogdan Dumitriu, Ioana Denisa Socol, Madalina Ioana Sorop and Bogdan Sorop
Healthcare 2025, 13(22), 2977; https://doi.org/10.3390/healthcare13222977 - 19 Nov 2025
Viewed by 1343
Abstract
Background and Objectives: This systematic review synthesized somatic and psychosocial determinants of postpartum sexual dysfunction (PSD) during the first 12 months after childbirth. Methods: Following PRISMA 2020 guidelines, we searched PubMed, Web of Science, and Scopus from inception to 4 August 2025 without [...] Read more.
Background and Objectives: This systematic review synthesized somatic and psychosocial determinants of postpartum sexual dysfunction (PSD) during the first 12 months after childbirth. Methods: Following PRISMA 2020 guidelines, we searched PubMed, Web of Science, and Scopus from inception to 4 August 2025 without language limits for the indexed records. Eligible studies enrolled postpartum women (≤12 months) and reported validated sexual outcomes (FSFI/FSFI-6, PISQ-12), dyspareunia, or sexual activity, examining breastfeeding, partner support/body image, perineal trauma/instrumentation, or postpartum perineal/musculoskeletal pain. Two reviewers independently screened and extracted data; risk of bias was assessed with a modified Newcastle–Ottawa Scale. Results: Of 1127 records screened, 15 studies were included. Perineal morbidity and early pain consistently tracked with worse sexual outcomes; assisted vaginal birth increased 6-month dyspareunia odds (OR 2.5). Breastfeeding was often associated with lower early sexual function and higher dyspareunia (6-month dyspareunia OR 4.4), with attenuation by 12 months. Higher partner/family support and more positive body image correlated with better FSFI scores. Heterogeneity in timing, measures, and adjustment precluded meta-analysis; results were narratively synthesized. Conclusions: Perineal trauma and early pain are dominant risk signals; breastfeeding-related symptoms exert early and context-dependent effects; psychosocial resources are protective. Full article
Show Figures

Figure 1

10 pages, 488 KB  
Article
Sexual Health in Patients with Atopic Dermatitis: A Cross-Sectional Study
by Natalia Juśko, Magdalena Masajada, Anna Żabówka, Adam Ćmiel, Paweł Brzewski and Adam Reich
Medicina 2025, 61(10), 1782; https://doi.org/10.3390/medicina61101782 - 2 Oct 2025
Viewed by 891
Abstract
Background and objectives: Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects not only physical health but also psychological well-being. While the emotional and social burden of AD is well documented, there is still limited research on how AD affects sexual [...] Read more.
Background and objectives: Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects not only physical health but also psychological well-being. While the emotional and social burden of AD is well documented, there is still limited research on how AD affects sexual health. The study aimed to evaluate quality of life (QoL), mental health, and risk factors for impaired sexual life, as well as their relationships. Materials and Methods: A total of 201 participants (96 patients with AD and 105 healthy controls) were enrolled in the study. Socio-demographic and clinical data were obtained using a specifically developed questionnaire. In addition, participants completed validated scales, including the DLQI, HADS, FSFI, IIEF-5, and SRSLQ. AD severity was assessed using the SCORAD questionnaire. Results: Our study found that patients with AD had statistically significantly higher mean anxiety (6.8 ± 3.6 vs. 5.0 ± 3.2; p < 0.001), depression (5.2 ± 3.4 vs. 3.9 ± 2.9, p < 0.01), and skin-related sexual dysfunction scores (15.0 ± 4.5 vs. 4.4 ± 4.7, p < 0.001), as well as QoL scores (12.3 ± 6.1 vs. 1.8 ± 3.1, p < 0.001), than healthy controls. Female AD patients reported higher values of depression and anxiety compared to male patients (5.9 ± 3.1 vs. 4.4 ± 3.5, p = 0.03, 7.6 ± 2.9 vs. 6.0 ± 4.1, p = 0.03, respectively) and lower FSFI scores compared to healthy women (24.8 ± 8.0 vs. 31.3 ± 3.0, p < 0.001). Deterioration in sexual health, assessed by the SRSLQ score, was strongly correlated with QoL impairment (R = 0.5, p < 0.001), anxiety (R = 0.51, p < 0.001), and depression (R = 0.5, p < 0.001). Finally, we found that sex life negatively correlates with AD severity (p=0.001), involvement of a genital area (p = 0.005), intensity of pruritus (r = 0.284, p = 0.005), and insomnia (r = 0.366, p < 0.001). Conclusions: AD significantly affects patients’ quality of life, including their sex life. Many factors associated with the disease also contribute to the deterioration of patients’ sexual health. Routine assessment of sexual life in dermatological practice, using validated tools, could facilitate early identification and support for affected patients. Significance: This study highlights the often-overlooked impact of atopic dermatitis on patients’ sexual health. Our findings demonstrate that sexual function is significantly impaired in individuals with atopic dermatitis—particularly among women—and that such dysfunction is closely associated with disease-related symptoms. These results have important implications for improving the quality of care provided to individuals affected by the condition. Full article
(This article belongs to the Section Dermatology)
Show Figures

Figure 1

14 pages, 531 KB  
Review
Sexual Dysfunction in Female Rectal and Anal Cancer Survivors: Pathophysiology, Clinical Management, and Integration into Survivorship Care
by Denise Drittone, Monia Specchia, Eva Mazzotti and Federica Mazzuca
Cancers 2025, 17(19), 3150; https://doi.org/10.3390/cancers17193150 - 28 Sep 2025
Viewed by 1809
Abstract
Background: Female Sexual dysfunction (FSD) is a common but under-recognized outcome of rectal and anal cancer treatment. While survival has improved, sexual health remains insufficiently addressed in survivorship care, warranting a multidisciplinary perspective. Methods: A narrative review of studies published between [...] Read more.
Background: Female Sexual dysfunction (FSD) is a common but under-recognized outcome of rectal and anal cancer treatment. While survival has improved, sexual health remains insufficiently addressed in survivorship care, warranting a multidisciplinary perspective. Methods: A narrative review of studies published between 2000 and 2025 was conducted, including clinical trials, cohort studies, and guideline documents addressing female sexual dysfunction after anorectal cancer treatment. Articles that were not pertinent to the research topic, outdated, or methodologically inadequate were excluded from the analysis. Results: Over 60% of female survivors experience FSD, including decreased libido, vaginal dryness, dyspareunia, and arousal difficulties. Causes include hormonal deficiency, nerve injury, and radiation fibrosis, compounded by psychological distress, altered body image, stoma-related stigma, and communication issues. The FSFI is commonly applied but lacks specificity for this population. Geographic disparities persist, with greater stigma and limited care access in low- and middle-income countries. Emerging therapies, such as immunotherapy, may mitigate FSD risk, though evidence is scarce. Conclusions: FSD after anorectal cancer is highly prevalent and significantly impacts quality of life, yet remains under-assessed in follow-up care. Multidisciplinary, culturally sensitive strategies integrating screening, psychosexual support, and tailored rehabilitation are urgently needed. Future research should address sexual outcomes more systematically, particularly in novel treatment contexts. Full article
(This article belongs to the Special Issue Long-Term Cancer Survivors: Rehabilitation and Quality of Life)
Show Figures

Figure 1

16 pages, 280 KB  
Article
Comparative Evaluation of Near-Term Oncologic, Urinary, Sexual, and Postoperative Outcomes in Rectal Cancer: Laparoscopic vs. Robotic Approaches
by Vagif Gurbanov, Veysel Umman, Osman Bozbiyik and Tayfun Yoldas
Medicina 2025, 61(10), 1726; https://doi.org/10.3390/medicina61101726 - 23 Sep 2025
Viewed by 899
Abstract
Background and Objectives: This study compares laparoscopic and robotic surgical techniques for rectal cancer, focusing on oncologic outcomes, mesocolic excision quality, lymph node yield, and postoperative sexual and urinary function, while also exploring patient satisfaction and recovery trajectories through clinical outcomes and validated [...] Read more.
Background and Objectives: This study compares laparoscopic and robotic surgical techniques for rectal cancer, focusing on oncologic outcomes, mesocolic excision quality, lymph node yield, and postoperative sexual and urinary function, while also exploring patient satisfaction and recovery trajectories through clinical outcomes and validated questionnaires. Materials and Methods: A retrospective analysis was conducted on 100 patients who underwent rectal cancer surgery between 2017 and 2021 at our tertiary center—53 underwent laparoscopic and 47 robotic surgery. Demographic data, tumor characteristics, and surgical details (procedure type, lymph node yield, morbidity, and mortality) were collected, and postoperative outcomes, including local recurrence, metastasis, need for reoperation, urinary incontinence, and sexual dysfunction, were compared. Functional outcomes were evaluated using the LARS questionnaire, Wexner score, IPSS, IIEF, and FSFI. Results: No significant differences were found in age, BMI, tumor size, or ASA scores between groups. Robotic surgery was associated with shorter hospital stays (p < 0.001), no conversions to open surgery (vs. 28.3% in laparoscopy), and zero cases of positive circumferential margins (vs. 35.8% in laparoscopy; p < 0.001). Lymphatic and perineural invasion rates were similar. Tumor recurrence occurred in four robotic and six laparoscopic cases, and factors significantly associated with recurrence included pathological stage, hospital stay, and adjuvant treatment. Robotic surgery showed improved urinary and sexual function, with lower Wexner, IPSS, and FSFI scores. Conclusions: Robotic surgery is a safe, effective, and patient-friendly alternative to laparoscopy, offering better preservation of continence and sexual function, reduced conversion rates, and shorter hospitalization, and should be considered the preferred approach in appropriately selected rectal cancer patients. Full article
(This article belongs to the Special Issue Advances in Colorectal Surgery and Oncology)
Back to TopTop