Search Results (448)

Background: The present study investigated the relation between dental inclination, colorimetric variation, and aesthetic perception according to the modification of incisor inclination. Smile aesthetics, shaped by morphological factors and patient perception, are vital for social attractiveness and treatment success. This study aimed to assess the effect of varying head tilt on the perceived colour of upper central incisors by simulating changes in torque of the tooth, as well as evaluate factors influencing the perception of an aesthetic smile, including morphological characteristics and gingival aesthetic parameters. Methods: The study was comprised of three stages: colour analysis, evaluation of micro- and mini-aesthetic smile features, and an image-based assessment to determine evaluator perceptions and overall smile attractiveness. A sample of 50 students with complete, lesion-free anterior dentition was analysed. To simulate the effect of orthodontic torque changes during colour analysis, subjects tilted their heads downward and upward, representing palatal and buccal crown torque, respectively. Standardized macro-intraoral photographs were captured under controlled lighting conditions using a DSLR camera stabilized on a tripod in the different positions: the neutral head position (p0), 15° upward (p + 15), and 15° downward (p − 15). Digital colour analysis was conducted in the CIELAB colour space (L*, a*, b*). In the next stage, focusing on micro- and mini-aesthetic evaluation, an additional 50 smiles were generated using artificial intelligence via the SmileCloud program—one digitally enhanced smile per subject—complementing the initial set of 50 spontaneous smiles. These 100 smile images were evaluated by 50 laypersons and 50 dentists using a visual analogue scale via an online questionnaire, in order to assess perceptions, determine smile attractiveness, and quantify gingival aesthetic parameters. Results: The statistically significant regression results are as follows: those for the L* values in all three head inclinations: downward (−15 degrees), upward (+15 degrees), and total tilting (−15 to +15 degrees), as well as for the a* values for downward tilting and the b* values for total tilting. When the head is tilted downwards, the central incisors are positioned retrusively, and the L* b* values reveal a darker and more yellowish appearance, whereas, with the head tilted upwards, the central incisors protrude, and L* a* values indicate a brighter and more greenish appear. In the evaluation stage of the smile aesthetics study, no significant differences were observed in the judgments between laypersons and dentists or between males and females. Smiles with a high or average anterior line, parallel arc, upward lip curvature, visible first/second premolars, a smile index of 5.08–5.87, and symmetry score of 1.04 were rated as more attractive. Significant asymmetries were observed between upper dental hemi-quadrants in gingival contour and interdental papilla height, highlighting subtle morphological variations relevant to smile aesthetics. Conclusions: Aesthetic assessment revealed that the findings suggest a measurable impact of head position on dental colour perception and aesthetic evaluation. Evaluator variables including profession and gender exerted negligible effects on aesthetic perception, whereas smile attractiveness features and gingival aesthetic parameters demonstrate significant clinical applicability in patient management. Full article

Background: Movement symmetry in the lower limbs is critical for biomechanical efficiency, injury prevention, and athletic performance. Lateral (sideways) jumping challenges force production and control in the frontal plane and provide a unique assessment of neuromuscular coordination that may not be detected through sagittal-plane tasks such as running or vertical jumping. This study aimed to evaluate limb asymmetries in isometric knee muscle torque and ground reaction forces (GRFs) during lateral jumps in healthy young women, using the Symmetry Index (SI) to quantify differences between limbs. Methods: Twenty right-limb dominant females (mean age: 20.65 ± 4.51 years) participated in the study. Isometric torque of the knee flexors and extensors was measured using a dynamometric testing station. Lateral jumps were performed onto dual force platforms, with GRF components (vertical (PD), anterior–posterior (AP), mediolateral (ML)) recorded separately for rightward and leftward jumps. SI was calculated for all parameters to determine side-to-side asymmetries, and paired Student’s t-tests were used for statistical comparisons. Results: Right-limb dominance was evident in both knee flexor and extensor torque. Significant asymmetries were observed across all GRF components, varying with jump direction. The trailing limb in each jump direction typically generated greater propulsion forces. In lateral jumps, the trailing limb is generally the leg positioned opposite to the direction of travel, playing a primary role in generating propulsion and absorbing forces during take-off. SI values revealed both inter-individual variability and consistent direction-dependent asymmetry patterns. Conclusions: The or-posterior and vertical components, with greater loading on the dominant leg. Muscle torque measurements also revealed imbalances, with flexors showing more symmetry than extensors. These findings underline the importance of assessing load symmetry to prevent injury and guide rehabilitation. Full article

Understanding how media narratives frame the Sustainable Development Goals (SDGs) is essential for global sustainability governance. This study presents a novel, data-driven analysis of 135,000 news articles mapped to SDGs 1–17 across 100 countries. Using polarity-based sentiment aggregation and principal component analysis (PCA), we reduce high-dimensional SDG sentiment profiles into a two-dimensional space and identify emergent clusters of countries using K-means. To contextualize these clusters, we integrate national-level indicators like Human Development Index (HDI), GDP per capita, CO₂ emissions, and press freedom scores, revealing robust correlations between sentiment structure and developmental attributes. Countries with higher HDI and freer media environments produce more optimistic and diverse SDG narratives, while lower-HDI countries tend toward more polarized or crisis-framed coverage. Our findings offer a typology of SDG discourse that reflects geopolitical, environmental, and informational asymmetries, providing new insights to support international policy coordination and sustainability communication. This work contributes a scalable methodology for monitoring global sustainability sentiment and underscores the importance of narrative equity in achieving Agenda 2030. Full article

It has always been a research topic for some meteorologists to design a new and reasonable calculation scheme of the intensity of the Tibetan Plateau (TP) summer monsoon (TPSM). Existing indices are defined based on dynamic factors. However, the intensity of the TPSM can also be influenced by thermal factors. We therefore propose defining a TPMI in terms of horizontal temperature advection within the main body of the TP. This provides a new index that directly quantifies the extent to which the thermal forcing in the TP region regulates the monsoon system. The new index emphasizes the importance of the atmospheric asymmetry structure in measuring TPSM strength, represents the variability of the TPSM circulation system, effectively reflects the meteorological elements, and accurately represents the climate variation. Tropospheric temperature (TT) and TPSM are linked by the new index. These significant centers of correlation are characterized by alternating positive and negative phases along the Eastern European Plain, across the Turan Plain, and into southwestern and northeastern China. The correlation coefficients are found to be significantly out of phase between high and low altitudes in the vertical direction. This research broadens our minds and helps us to develop a new approach to measuring TPSM strength. It can also predict extreme weather events in advance based on TPMI changes, providing a scientific basis for disaster warnings and the management of agriculture and water resources. Full article

Understanding patterns of interhemispheric asymmetry is crucial for monitoring neuroplastic changes during post-stroke motor rehabilitation. However, conventional laterality indices often pose computational challenges when applied to functional near-infrared spectroscopy (fNIRS) data due to the bidirectional hemodynamic responses. In this study, we analyze fNIRS recordings from 15 post-stroke patients undergoing motor imagery brain–computer interface training across multiple sessions. We compare traditional laterality coefficients with a novel task response asymmetry coefficient (TRAC), which quantifies differential hemispheric involvement during motor imagery tasks. Both indices are calculated for oxygenated and deoxygenated hemoglobin responses using general linear model coefficients, and their day-to-day dynamics are assessed with linear regression. The proposed TRAC demonstrates greater sensitivity than conventional measures, revealing significantly higher oxygenated hemoglobin TRAC values (0.18 ± 0.19 vs. −0.05 ± 0.20, p < 0.05) and lower deoxygenated hemoglobin TRAC values (−0.15 ± 0.27 vs. 0.04 ± 0.23, p < 0.05) in lesioned compared to intact hemispheres. Among patients who exhibit substantial motor recovery, distinct daily TRAC dynamics were observed, with statistically significant temporal trends. Overall, the novel TRAC metric offers enhanced discrimination of interhemispheric asymmetry patterns and captures temporal neuroplastic changes not detected by conventional indices, providing a more sensitive biomarker for tracking rehabilitation progress in post-stroke brain–computer interface applications. Full article

Background/Objectives: Inter-limb asymmetry of a given variable for vertical jumps is commonly assessed in both healthy individuals and those undergoing rehabilitation post-injury. The aim of this study was to compare the asymmetry index between the take-off and landing of a single-leg counter movement jump (CMJ), as well as between females and males. Methods: Twenty-three healthy females (age: 21.5 ± 1.6 years) and twenty-three healthy males (age: 21.1 ± 1.8 years) participated in this study. The assessment of two asymmetry indices (AI1 and AI2) was conducted for the peak vertical ground reaction force (PVGRF) and maximum power (MP) during single-leg CMJ take-offs and landings performed on the force platform. Results: The analysis showed significant main effects (p < 0.001) for the phase factor (only AI2) and for the gender factor (only AI1). Moreover, there was a non-significant interaction effect between the phase factor and gender factor (p = 0.476). Pairwise comparisons revealed significant differences in the values of (1) AI2 between the take-off and landing (p < 0.001) and (2) AI1 between females and males (p < 0.001). Conclusions: Findings showed significant effects of the phase factor (only for AI2) and gender factor (only for AI1) on the magnitude of inter-limb asymmetry during single-leg CMJs. Furthermore, this study reported the significantly higher asymmetry of the PVGRF and MP for landing than take-off, which may result from difficulties in controlling the jumper’s landing technique on one foot at higher velocity. In addition, the assessment of asymmetry for single-leg CMJs using AI1 should be performed separately for females and males, as opposed to AI2. Participants of both genders generally demonstrated a higher AI level for the power than for the force. Full article

This study aims to investigate asymmetries in muscle activation and co-contraction of main lower limb muscles during flamenco Zap-3 footwork with consideration of the footwork speed and dancer proficiency. Twelve flamenco dancers participated, including six professionals and six amateurs. Each participant performed the Zap-3 sequence under three speed conditions: 160 beats per minute (bpm), 180 bpm and the fastest speed level (F). The normalized surface electromyography was recorded in the gastrocnemius medialis (GM), biceps femoris (BF), tibialis anterior (TA) and rectus femoris (RF) in the dominant (DL) and non-dominant leg (NDL). The co-contraction index was also calculated for selected muscle pairs. The results showed that significant asymmetries occurred only in professional dancers and exclusively at the F speed level. Specifically, the value of the GM in the NDL was higher than that of the DL (p < 0.05, d = 1.97); the value of the BF in the DL was higher than that of the NDL (p < 0.05, d = 1.86) and the co-contraction index of BF/RF in the DL was higher than that of the NDL (p < 0.05, d = 1.87). Understanding these asymmetries may help to inform individualized training strategies aimed at optimizing performance and reducing potential risks. Full article

Background: This study aimed to examine the effects of an 8-week plyometric training program on lower-limb explosive strength, jump performance, musculotendinous stiffness, reactive strength index (RSI), and multidirectional speed in elite Polish badminton players. Methods: Twenty-four athletes were randomly assigned to either an experimental group (n = 15), which supplemented their regular badminton training with plyometric exercises, or a control group (n = 15), which continued standard technical training. Performance assessments included squat jump (SJ), countermovement jump (CMJ), single-leg jumps, sprint tests (5 m, 10 m), lateral movements, musculotendinous stiffness, and RSI measurements. Results: The experimental group showed statistically significant improvements in jump height, power output, stiffness, and 10 m sprint and lateral slide-step performance (p < 0.05), with large effect sizes. No significant changes were observed in the control group. Single-leg jump improvements suggested potential benefits for addressing lower-limb asymmetries. Conclusions: An 8-week plyometric intervention significantly enhanced lower-limb explosive performance and multidirectional movement capabilities in young badminton players. These findings support the integration of targeted plyometric training into regular training programs to optimize physical performance, improve movement efficiency, and potentially reduce injury risk in high-intensity racket sports. Full article

The presence of Active Galaxy Nuclei (AGN) can affect the morphological classification of galaxies. This work aims to determine how the contribution of AGN affects the most-used morphological parameters down to the redshift of z ∼ 2 in COSMOS-like conditions. We use a sample of >2000 local non-active galaxies, with a well-known visual morphological classification, and add an AGN as an unresolved component that contributes to the total galaxy flux with 5–75%. We moved all the galaxies to lower magnitudes (higher redshifts) to map the conditions in the COSMOS field, and we measured six morphological parameters. The greatest impact on morphology occurs when considering the combined effect of magnitude, redshift, and AGN, with spiral galaxies being the most affected. In general, all the concentration parameters change significantly if the AGN contribution is >25% and the magnitude > 23. We find that the GINI coefficient is the most stable in terms of AGN and magnitude/redshift, followed by the moment of light (M20), Conselice–Bershady (CCON), and finally the Abraham (CABR) concentration indexes. We find that, when using morphological parameters, the combination of CABR, CCON, and asymmetry is the most effective in classifying active galaxies at high-redshift, followed by a combination of CABR and GINI. Full article

In this study, the effects of walking speed on lower limb muscle activity and gait parameters during over-ground walking were investigated in individuals with chronic stroke. Twenty-four patients with chronic stroke participated in a cross-sectional repeated-measures study, walking 20 m at three different speeds: slow (80% of self-selected speed), self-selected, and maximal speed. Surface electromyography was used to measure muscle activity in five paretic-side muscles (rectus femoris, biceps femoris, tibialis anterior, gastrocnemius, and gluteus medius), while gait parameters, including stride length, stance and swing phases, single-limb support time, and the gait asymmetry index were assessed using a triaxial accelerometer. As walking speed increased, activity in the rectus femoris, biceps femoris, and gastrocnemius muscles significantly increased during the stance and swing phases (p < 0.05), whereas the gluteus medius activity tended to decrease. Stride length on the paretic and non-paretic sides significantly increased with faster walking speed (p < 0.05); however, no significant improvements were observed in other gait parameters or gait asymmetry. These findings suggest that although increasing walking speed enhances specific muscle activities, it does not necessarily improve overall gait quality or symmetry. Therefore, rehabilitation programs should incorporate multidimensional gait training that addresses speed and neuromuscular control factors such as balance and proprioception. Full article

Given the high neuromechanical demands and frequent asymmetries in badminton, this study investigated the impact of a four-week asymmetry-targeted intervention on single-leg hop performance in elite junior badminton players and examined whether asymmetry-based indices could predict training responsiveness. Twenty-two national-level athletes (aged 15–18) were randomized into an experimental group (EG) undergoing neuromechanical training with EMG biofeedback or a control group (CG) following general plyometric exercises. Key performance metrics—Jump Height, Reactive Strength Index (RSI), Peak Power, and Active Stiffness—were evaluated pre- and post-intervention. Two novel composite indices, Force Efficiency Ratio (FER) and Asymmetry Impact Index (AII), were computed to assess force production efficiency and asymmetry burden. The EG showed significant improvements in Jump Height (p = 0.030), RSI (p = 0.012), and Peak Power (p = 0.028), while the CG showed no significant changes. Contrary to initial hypotheses, traditional asymmetry metrics showed no significant correlations with performance variables (r < 0.1). Machine learning models (Random Forest) using FER and AII failed to classify responders reliably (AUC = 0.50). The results suggest that targeted interventions can improve lower-limb explosiveness in youth athletes; however, both traditional and composite asymmetry indices may not reliably predict training outcomes in small elite groups. The results highlight the need for multidimensional and individualized approaches in athlete diagnostics and training optimization, especially in asymmetry-prone sports like badminton. Full article

Food safety concerns related to pesticide residues in fruits and vegetables have increased globally, particularly in regions where monitoring programs are scarce or inconsistent. This study provides the first multi-year evaluation of pesticide contamination and associated dietary risks in Cape Verde, an African island nation increasingly reliant on imported produce. A total of 570 samples of fruits and vegetables—both locally produced and imported—were collected from major markets across the country between 2017 and 2020 and analyzed using validated multiresidue methods based on gas chromatography coupled to Ion Trap mass spectrometry (GC-IT-MS/MS), and both gas and liquid chromatography coupled to triple quadrupole tandem mass spectrometry (GC-QqQ-MS/MS and LC-QqQ-MS/MS). Residues were detected in 63.9% of fruits and 13.2% of vegetables, with imported fruits showing the highest contamination levels and diversity of compounds. Although only one sample exceeded the maximum residue limits (MRLs) set by the European Union, 80 different active substances were quantified—many of them not authorized under the current EU pesticide residue legislation. Dietary exposure was estimated using median residue levels and real consumption data from the national nutrition survey (ENCAVE 2019), enabling a refined risk assessment based on actual consumption patterns. The cumulative hazard index for the adult population was 0.416, below the toxicological threshold of concern. However, when adjusted for children aged 6–11 years—taking into account body weight and relative consumption—the cumulative index approached 1.0, suggesting a potential health risk for this vulnerable group. A limited number of compounds, including omethoate, oxamyl, imazalil, and dithiocarbamates, accounted for most of the risk. Many are banned or heavily restricted in the EU, highlighting regulatory asymmetries in global food trade. These findings underscore the urgent need for strengthened residue monitoring in Cape Verde, particularly for imported products, and support the adoption of risk-based food safety policies that consider population-specific vulnerabilities and mixture effects. The methodological framework used here can serve as a model for other low-resource countries seeking to integrate analytical data with dietary exposure in a One Health context. Full article

Background: Hypometabolism of the thalamus has been reported in epilepsy patients. This study aimed to investigate the prognostic value of thalamic metabolic activity in children with epilepsy. Methods: A total of 200 children with epilepsy and 237 children without epilepsy (sex- and age-matched control group) underwent 18F-FDG PET/CT in this study. Localization of the interictal hypometabolic epileptic focus was performed visually. Bilateral thalamic metabolic activity was evaluated qualitatively (thalamic FDG uptake in relation to the cerebral cortex) and semi-quantitatively (SUV max, normalized SUV (ratio to ipsilateral cerebellum), and absolute asymmetric index (AAI). Results: A total of 133 patients (66.5%) with epilepsy showed cerebral cortical hypometabolism in the interictal 18F-FDG PET study; there were 76 patients on the right side, 55 patients on the left side, and two patients on both sides. Of these 133 patients, 45 also had visually observed asymmetric hypometabolism in the thalamus. Semi-quantitatively, asymmetry was more prominent in epileptic patients. AAI was a more sensitive variable than other variables. Average AAIs were 3.89% and 7.36% in the control and epilepsy patients, respectively. Metabolic activity in the thalami was significantly reduced in epileptic patients compared to the control group. Associated hypometabolism of the ipsilateral thalamus was observed in 66.5% of epileptic patients with a focal cortical defect semi-quantitatively. Overall, 61 out of 200 patients showed thalamus hypometabolism. Some 51 out of 61 patients (83.6%) with thalamus hypometabolism showed refractory disease; however, the refractory disease was noted in 90 out of 139 (64.7%) patients without thalamus hypometabolism. Brain surgery was performed in 86 epileptic patients (43%). Some 35 out of 86 patients had thalamus hypometabolism. Recurrence of epilepsy was observed more in patients with thalamus hypometabolism (48% vs. 25%), with p ≤ 0.01. Conclusion: This study suggests that patients with thalamus metabolic abnormalities may be more medically resistant to therapy and less responsive to surgical treatments. Therefore, the thalamus metabolic abnormality could be used as a prognostic sign in pediatric epilepsy. Recent studies have also suggested that incorporating thalamic metabolic data into clinical workflows may improve the stratification of treatment-resistant epilepsy in children. Full article

Maintaining body symmetry in sports characterized by high lateralization is crucial for optimizing long-term athletic performance and mitigating injury risk. This study aimed to evaluate the extent of morphological asymmetry in anthropometric features among elite professional fencers. Additionally, the presence of functional asymmetry and its associations with morphological asymmetry were assessed. Thirty-two Polish adult female fencers, aged 18–33 yrs, were examined. Data collection involved a questionnaire survey, anthropometric measurements, calculation of anthropological indices, and assessment of functional asymmetry. For the 24 bilateral anthropometric features, small differences were found in seven characteristics: foot length, subscapular skinfold thickness, upper arm circumference, minimum and maximum forearm circumference, upper limb length, and arm circumference in tension. Morphological asymmetry index did not exceed 5%. Left-sided lateralization of either the upper or lower limbs was associated with significantly high asymmetry, specifically indicating larger minimum forearm circumferences in the right limb. Continuous, individualized monitoring of morphological asymmetry and its direction in athletes is essential, demanding concurrent consideration of functional lateralization. This ongoing assessment establishes a critical baseline for evaluating training adaptations, reducing injury susceptibility, and optimizing rehabilitation strategies. Deeper investigation of symmetry within non-dominant limbs is warranted to enhance our understanding. Full article

Scientific knowledge and international collaboration are critical to achieving the Sustainable Development Goals (SDGs). This study conducts a large-scale bibliometric analysis of 49.4 million publications indexed in the Web of Science (1945–2023) related to the SDGs, with a specific focus on SDG 3 (Good Health and Well-Being). Since 1992, SDG 3 has accounted for 58% of SDG-related scientific output. Using K-means clustering and network analysis, we classified countries/regions by research productivity and mapped core–periphery collaboration structures. Results reveal a sharp concentration: the United States, China, England, and Germany account for 51.65% of publications. In contrast, the group composed of the 195 least productive countries and territories accounts for approximately 5% of the total scientific output on the SDGs, based on the same clustering method. Collaboration patterns mirror this inequality, with 84.97% of partnerships confined to the core group and only 2.81% involving core–periphery cooperation. These asymmetries limit the capacity of developing regions to generate health research aligned with local needs, constraining equitable progress toward SDG 3. Expanding scientific cooperation, fostering North–South and South–South collaborations, and ensuring equitable research funding are essential to promote inclusive knowledge production and support sustainable global health. Full article