- Article
Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria
- Stefan Freischem,
- Immanuel Grimm,
- Arancha López-Pérez,
- Dieter Willbold,
- Burkhard Klenke,
- Cuong Vuong,
- Andrew J. Dingley and
- Oliver H. Weiergräber
Novel antimicrobial strategies are urgently required because of the rising threat of multi drug resistant bacterial strains and the infections caused by them. Among the available target structures, the so-called penicillin binding proteins are of par...