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Journal = Biomimetics
Section = Biomimetic Surfaces and Interfaces

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15 pages, 2557 KiB  
Article
Multiline Laser Interferometry for Non-Contact Dynamic Morphing of Hierarchical Surfaces
by Biagio Audia, Caterina Maria Tone, Pasquale Pagliusi, Alfredo Mazzulla, George Papavieros, Vassilios Constantoudis and Gabriella Cipparrone
Biomimetics 2025, 10(8), 486; https://doi.org/10.3390/biomimetics10080486 - 23 Jul 2025
Viewed by 348
Abstract
Hierarchical surface structuring is a critical aspect of advanced materials design, impacting fields ranging from optics to biomimetics. Among several laser-based methods for complex structuring of photo-responsive surfaces, the broadband vectorial interferometry proposed here offers unique performances. Such a method leverages a polychromatic [...] Read more.
Hierarchical surface structuring is a critical aspect of advanced materials design, impacting fields ranging from optics to biomimetics. Among several laser-based methods for complex structuring of photo-responsive surfaces, the broadband vectorial interferometry proposed here offers unique performances. Such a method leverages a polychromatic laser source, an unconventional choice for holographic encoding, to achieve deterministic multiscale surface structuring through interference light patterning. Azopolymer films are used as photosensitive substrates. By exploring the interaction between optomechanical stress modulations at different spatial periodicities induced within the polymer bulk, we demonstrate the emergence of hierarchical Fourier surfaces composed of multiple deterministic levels. These structures range from sub-micrometer to tens of micrometers scale, exhibiting a high degree of control over their morphology. The experimental findings reveal that the optical encoding scheme significantly influences the resulting topographies. The polarization light patterns lead to more regular and symmetric hierarchical structures compared to those obtained with intensity patterns, underscoring the role of vectorial light properties in controlling surface morphologies. The proposed method is fully scalable, compatible with more complex recording schemes (including multi-beam interference), and it is applicable to a wide range of advanced technological fields. These include optics and photonics (diffractive elements, polarimetric devices), biomimetic surfaces, topographical design, information encoding, and anti-counterfeiting, offering a rapid, reliable, and versatile strategy for high-precision surface structuring at a submicrometric scale. Full article
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33 pages, 5578 KiB  
Review
Underwater Drag Reduction Applications and Fabrication of Bio-Inspired Surfaces: A Review
by Zaixiang Zheng, Xin Gu, Shengnan Yang, Yue Wang, Ying Zhang, Qingzhen Han and Pan Cao
Biomimetics 2025, 10(7), 470; https://doi.org/10.3390/biomimetics10070470 - 17 Jul 2025
Viewed by 549
Abstract
As an emerging energy-saving approach, bio-inspired drag reduction technology has become a key research direction for reducing energy consumption and greenhouse gas emissions. This study introduces the latest research progress on bio-inspired microstructured surfaces in the field of underwater drag reduction, focusing on [...] Read more.
As an emerging energy-saving approach, bio-inspired drag reduction technology has become a key research direction for reducing energy consumption and greenhouse gas emissions. This study introduces the latest research progress on bio-inspired microstructured surfaces in the field of underwater drag reduction, focusing on analyzing the drag reduction mechanism, preparation process, and application effect of the three major technological paths; namely, bio-inspired non-smooth surfaces, bio-inspired superhydrophobic surfaces, and bio-inspired modified coatings. Bio-inspired non-smooth surfaces can significantly reduce the wall shear stress by regulating the flow characteristics of the turbulent boundary layer through microstructure design. Bio-inspired superhydrophobic surfaces form stable gas–liquid interfaces through the construction of micro-nanostructures and reduce frictional resistance by utilizing the slip boundary effect. Bio-inspired modified coatings, on the other hand, realize the synergistic function of drag reduction and antifouling through targeted chemical modification of materials and design of micro-nanostructures. Although these technologies have made significant progress in drag reduction performance, their engineering applications still face bottlenecks such as manufacturing process complexity, gas layer stability, and durability. Future research should focus on the analysis of drag reduction mechanisms and optimization of material properties under multi-physical field coupling conditions, the development of efficient and low-cost manufacturing processes, and the enhancement of surface stability and adaptability through dynamic self-healing coatings and smart response materials. It is hoped that the latest research status of bio-inspired drag reduction technology reviewed in this study provides a theoretical basis and technical reference for the sustainable development and energy-saving design of ships and underwater vehicles. Full article
(This article belongs to the Section Biomimetic Surfaces and Interfaces)
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14 pages, 5041 KiB  
Article
Coating Process of Oil and Gas Well Pipeline Preventive Repair Materials Inspired by Remora Suckerfish Structure
by Yuliang Lu, Dongtao Liu, Jiming Song, Qiaogang Xiao, Kezheng Du, Xinjie Wei, Lifeng Dang, Yajun Yu and Huiyan Zhao
Biomimetics 2025, 10(7), 436; https://doi.org/10.3390/biomimetics10070436 - 2 Jul 2025
Viewed by 389
Abstract
To meet the special needs of preventive maintenance for oil and gas well pipelines, this study conducts a geometric dissection of remora suckerfish based on bionics. It combines the biological features with fiberboard tape and uses the discrete element method to construct a [...] Read more.
To meet the special needs of preventive maintenance for oil and gas well pipelines, this study conducts a geometric dissection of remora suckerfish based on bionics. It combines the biological features with fiberboard tape and uses the discrete element method to construct a particle model of solvent-free, epoxy-reinforced polymer materials, determining relevant parameters. The model accuracy is verified through volumetric density and drop tests, and the optimal parameter combination of the remora-inspired structure is obtained via multi-factor simulation analysis. Comparative tests confirm that the bionic structure enhances stability by approximately 43.29% compared to the original structure, effectively avoiding insufficient strength. It successfully addresses the gravitational segregation and fluid shear caused by uneven coating thickness, ensures stable and reliable interfacial properties of the composite structure during service, and provides strong support for the practical application of related materials in the preventive repair of oil and gas well pipelines. The findings promote the upgrade of oil and gas pipeline maintenance strategies from “passive response” to “active prevention”, laying the core technical foundation for the resilience of energy infrastructure. Full article
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14 pages, 6262 KiB  
Article
Effect of Surfactant on Bubble Formation on Superhydrophobic Surface in Quasi-Static Regime
by Hangjian Ling, John Ready and Daniel O’Coin
Biomimetics 2025, 10(6), 382; https://doi.org/10.3390/biomimetics10060382 - 7 Jun 2025
Viewed by 681
Abstract
We experimentally studied the effect of a surfactant on bubble formation on a superhydrophobic surface (SHS). The bubble was created by injecting gas through an orifice on the SHS at a constant flow rate in the quasi-static regime. The surfactant, 1-pentanol, was mixed [...] Read more.
We experimentally studied the effect of a surfactant on bubble formation on a superhydrophobic surface (SHS). The bubble was created by injecting gas through an orifice on the SHS at a constant flow rate in the quasi-static regime. The surfactant, 1-pentanol, was mixed with water at concentration C ranging from 0 to 0.08 mol/L, corresponding to surface tension σ ranging from 72 to 43 mN/m. We found that as C increased, the bubble detachment volume (Vd) and maximum bubble base radius (Rdmax) decreased. For a low surfactant concentration, the static contact angle θ0 remained nearly constant, and Vd and Rdmax decreased due to lower surface tensions, following the scaling laws Rdmax~σ1/2 and Vd~σ3/2. The bubble shapes at different concentrations were self-similar. The bubble height, bubble base radius, radius at the bubble apex, and neck radius all scaled with the capillary length. For high surfactant concentrations, however, θ0 was greatly reduced, and Vd and Rdmax decreased due to the combined effects of reduced θ0 and smaller σ. Lastly, we found that the surfactant had a negligible impact on the forces acting on the bubble, except for reducing their magnitudes, and had little effect on the dynamics of bubble pinch-off, except for reducing the time and length scales. Overall, our results provide a better understanding of bubble formation on complex surfaces in complex liquids. Full article
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35 pages, 11695 KiB  
Article
Polymorphism in Glu-Phe-Asp Proteinoids
by Panagiotis Mougkogiannis and Andrew Adamatzky
Biomimetics 2025, 10(6), 360; https://doi.org/10.3390/biomimetics10060360 - 3 Jun 2025
Viewed by 498
Abstract
Glu-Phe-Asp (GFD) proteinoids represent a class of synthetic polypeptides capable of self-assembling into microspheres, fibres, or combinations thereof, with morphology dramatically influencing their electrical properties. Extended recordings and detailed waveforms demonstrate that microspheres generate rapid, nerve-like spikes, while fibres exhibit consistent and gradual [...] Read more.
Glu-Phe-Asp (GFD) proteinoids represent a class of synthetic polypeptides capable of self-assembling into microspheres, fibres, or combinations thereof, with morphology dramatically influencing their electrical properties. Extended recordings and detailed waveforms demonstrate that microspheres generate rapid, nerve-like spikes, while fibres exhibit consistent and gradual variations in voltage. Mixed networks integrate multiple components to achieve a balanced output. Electrochemical measurements show clear differences. Microspheres have a low capacitance of 1.926±5.735μF. They show high impedance at 6646.282±178.664 Ohm. Their resistance is low, measuring 15,830.739 ± 652.514 mΩ. This structure allows for quick ionic transport, leading to spiking behaviour. Fibres show high capacitance (9.912±0.171μF) and low impedance (209.400±0.286 Ohm). They also have high resistance (163,067.613 ± 9253.064 mΩ). This combination helps with charge storage and slow potential changes. The 50:50 mixture shows middle values for all parameters. This confirms that hybrid electrical properties have emerged. The differences come from basic structural changes. Microspheres trap ions in small, round spaces. This allows for quick release. In contrast, fibers spread ions along their length. This leads to slower wave propagation. In mixed systems, diverse voltage zones emerge, suggesting cooperative dynamics between morphologies. This electrical polymorphism in simple proteinoid systems may explain complexity in biological systems. This study shows that structural polymorphism in GFD proteinoids affects their electrical properties. This finding is significant for biomimetic computing and sheds light on prebiotic information-processing systems. Full article
(This article belongs to the Section Biomimetic Surfaces and Interfaces)
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18 pages, 12819 KiB  
Article
Investigation of Droplet Spreading and Rebound Dynamics on Superhydrophobic Surfaces Using Machine Learning
by Samo Jereb, Jure Berce, Robert Lovšin, Matevž Zupančič, Matic Može and Iztok Golobič
Biomimetics 2025, 10(6), 357; https://doi.org/10.3390/biomimetics10060357 - 1 Jun 2025
Viewed by 715
Abstract
The spreading and rebound of impacting droplets on superhydrophobic interfaces is a complex phenomenon governed by the interconnected contributions of surface, fluid and environmental factors. In this work, we employed a collection of 1498 water–glycerin droplet impact experiments on monolayer-functionalized laser-structured aluminum samples [...] Read more.
The spreading and rebound of impacting droplets on superhydrophobic interfaces is a complex phenomenon governed by the interconnected contributions of surface, fluid and environmental factors. In this work, we employed a collection of 1498 water–glycerin droplet impact experiments on monolayer-functionalized laser-structured aluminum samples to train, validate and optimize a machine learning regression model. To elucidate the role of each influential parameter, we analyzed the model-predicted individual parameter contributions on key descriptors of the phenomenon, such as contact time, maximum spreading coefficient and rebound efficiency. Our results confirm the dominant contribution of droplet impact velocity while highlighting that the droplet spreading phase appears to be independent of surface microtopography, i.e., the depth and width of laser-made features. Interestingly, once the rebound transitions to the retraction stage, the importance of the unwetted area fraction is heightened, manifesting in higher rebound efficiency on samples with smaller distances between laser-fabricated microchannels. Finally, we exploited the trained models to develop empirical correlations for predicting the maximum spreading coefficient and rebound efficiency, both of which strongly outperform the currently published models. This work can aid future studies that aim to bridge the gap between the observed macroscale surface-droplet interactions and the microscale properties of the interface or the thermophysical properties of the fluid. Full article
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14 pages, 6772 KiB  
Article
Water Impact on Superhydrophobic Surface: One Hydrophilic Spot Morphing and Controlling Droplet Rebounce
by Jiali Guo, Haoran Zhao, Ching-Wen Lou and Ting Dong
Biomimetics 2025, 10(5), 319; https://doi.org/10.3390/biomimetics10050319 - 15 May 2025
Viewed by 510
Abstract
Motion control of droplets undergoing collisions with solid surface is required in a number of technological and industrial situations. Droplet dynamics after lifting off is often unpredictable, leading to a major problem in many technologies that droplets move in uncontrolled and potentially undesirable [...] Read more.
Motion control of droplets undergoing collisions with solid surface is required in a number of technological and industrial situations. Droplet dynamics after lifting off is often unpredictable, leading to a major problem in many technologies that droplets move in uncontrolled and potentially undesirable ways. Herein, this work shows that well-designed surface chemistry can produce an accurate control of force transmission to impinging droplets, permitting precise controlled droplet rebounce. The non-wetting surfaces (superhydrophobic), which mimics the water-repellent mechanism of lotus leaves via micro-to-nanoscale hierarchical morphology, with patterned “defect” of extreme wettability (hydrophilic), are synthesized by photolithography using only one inexpensive fluorine-free reagent (methyltrichlorosilane). The contact line of impinging droplet during flatting and receding is free to move on the superhydrophobic region and pinned as it meets with the hydrophilic defect, which introduces a net surface tension force allowing patterned droplet deposition, controlled droplet splitting, and directed droplet rebound. The work also achieves controlled vertical rebound of impinging droplets on inclined surfaces by controlling defect’s size, impact position, and impact velocity. This research demonstrates pinning forces as a general strategy to attain sophisticated droplet motions, which opens an avenue in future explorations, such as matter transportation, energy transformation, and object actuation. Full article
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23 pages, 5262 KiB  
Review
Directional Liquid Transport on Biomimetic Surface with Wedge-Shaped Pattern: Mechanism, Construction, and Applications
by Qing’an Meng, Junjie Zhou, Jie Pang, Luofeng Wang, Kaicheng Yang, Zhangcan Li and Jiayu Xie
Biomimetics 2025, 10(5), 298; https://doi.org/10.3390/biomimetics10050298 - 8 May 2025
Viewed by 614
Abstract
Natural organisms have evolved highly sophisticated mechanisms for managing water across a broad range of environmental conditions, from arid to highly humid regions. Among these mechanisms, directional liquid transport (DLT) is particularly noteworthy, as it relies on structural designs that facilitate the spontaneous [...] Read more.
Natural organisms have evolved highly sophisticated mechanisms for managing water across a broad range of environmental conditions, from arid to highly humid regions. Among these mechanisms, directional liquid transport (DLT) is particularly noteworthy, as it relies on structural designs that facilitate the spontaneous movement of liquids along predefined pathways without the need for external energy sources. The increasing interest in DLT systems is primarily driven by their potential applications in fields such as microfluidics, water harvesting, and biomedical engineering. The focus on DLT is motivated by its ability to inspire efficient, energy-independent liquid transport technologies, which hold significant promise for both fundamental research and practical applications. Notably, wedge-shaped DLT systems have emerged as a particularly promising area of study due to their advantages in terms of manufacturability, liquid collection efficiency, and scalability—attributes that are essential for industrial deployment. This review seeks to explore natural wedge-based DLT systems, providing an in-depth analysis of their underlying principles and their potential for engineering replication. The discussion includes examples from nature, such as desert beetles and spider silk, and explores the theoretical mechanisms governing these systems, including the role of surface energy gradients and Laplace pressure. Additionally, the review highlights advanced fabrication techniques, such as photolithography and laser micromachining, which are crucial for the development of these systems in practical applications. Full article
(This article belongs to the Section Biomimetic Surfaces and Interfaces)
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17 pages, 7106 KiB  
Article
Effect of Biomimetic Fish Scale Texture on Reciprocating Friction Pairs on Interfacial Lubricating Oil Transport
by Tao Sun, Zhijun Yan, Lixia Xue, Yuanyuan Jiang and Shibo Wu
Biomimetics 2025, 10(4), 248; https://doi.org/10.3390/biomimetics10040248 - 17 Apr 2025
Viewed by 472
Abstract
Focusing on the difficulty of lubrication in the scavenging port area of a cylinder liner of an actual marine two-stroke diesel engine, the transportation of interface lubricating oil was studied. In this paper, a biomimetic fish scale texture composed of fan-shaped and arc-shaped [...] Read more.
Focusing on the difficulty of lubrication in the scavenging port area of a cylinder liner of an actual marine two-stroke diesel engine, the transportation of interface lubricating oil was studied. In this paper, a biomimetic fish scale texture composed of fan-shaped and arc-shaped curves is designed, and the numerical simulation model is established according to this texture. Through simulation research, the variation rules of pressure distribution, interfacial velocity, and outlet volume flow rate on the biomimetic fish scale texture surface at different velocities and temperatures are obtained. Moreover, the biomimetic fish scale texture is machined on the surface of a reciprocating friction pair by laser etching, and the oil transport speed of the interface is tested under different conditions. The results show that the existence of the biomimetic fish scale texture on the friction pair can effectively improve the pressure difference between interfaces during reciprocating motion. The pressure difference enhances the flow properties of interfacial lubricating oil, thereby improving its mass transport capacity. In addition, increasing the movement speed and oil temperature can increase the oil transport speed of interfacial lubricating oil. The results of the experiment suggest that, under continuous and discontinuous interface conditions, compared with a friction pair without texture, the improvement rate of the lubricating oil transport speed at the interface of the friction pair with the biomimetic fish scale texture can reach 40.7% and 69.1%, respectively. Full article
(This article belongs to the Section Biomimetic Surfaces and Interfaces)
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4 pages, 1266 KiB  
Editorial
Biological Attachment Systems and Biomimetics—In Memory of William Jon P. Barnes
by Thies H. Büscher and Stanislav N. Gorb
Biomimetics 2025, 10(4), 220; https://doi.org/10.3390/biomimetics10040220 - 2 Apr 2025
Viewed by 316
Abstract
Any system preventing the separation of two surfaces may be defined as an attachment system [...] Full article
(This article belongs to the Special Issue Biological Attachment Systems and Biomimetics)
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11 pages, 3890 KiB  
Article
Elastomer with Microchannel Nanofiber Array Inspired by Rabbit Cornea Achieves Rapid Liquid Spreading and Reduction of Frictional Vibration Noise
by Bowen Zhang, Lei Jiang and Ruochen Fang
Biomimetics 2025, 10(3), 164; https://doi.org/10.3390/biomimetics10030164 - 7 Mar 2025
Viewed by 715
Abstract
Reducing friction-induced squeal noise is a common issue in daily life and industrial production, particularly for elastomers. However, adjusting structure and wettability in wet environments to solve the friction-induced squeal noise remains a challenge. Here, inspired by rabbit corneas, a microchannel nanofiber array [...] Read more.
Reducing friction-induced squeal noise is a common issue in daily life and industrial production, particularly for elastomers. However, adjusting structure and wettability in wet environments to solve the friction-induced squeal noise remains a challenge. Here, inspired by rabbit corneas, a microchannel nanofiber array composite structure superhydrophilic elastomer material was prepared to achieve rapid liquid spreading and optimize liquid distribution. Researchers have found that when the depth of the groove microchannel is 400 μm and the length of the nanofiber is 5000 nm, water rapidly spreads on the surface in only 430 ms. This reduces self-excited vibration caused by friction, thereby reducing squealing noise by 20 decibels (dB). This article proposes a novel and direct biomimetic squealing noise reduction strategy, which has great potential in solving friction vibration noise problems in industry and daily life, such as automotive wiper blades, engines, oil lubricated bearings, etc. Full article
(This article belongs to the Section Biomimetic Surfaces and Interfaces)
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14 pages, 37436 KiB  
Article
Desert Beetle-Inspired Hybrid Wettability Surfaces for Fog Collection Fabricated by 3D Printing and Atmospheric Pressure Plasma Treatment
by Chia-Yi Lin, Ting-An Teng, Haw-Kai Chang and Po-Yu Chen
Biomimetics 2025, 10(3), 143; https://doi.org/10.3390/biomimetics10030143 - 26 Feb 2025
Cited by 2 | Viewed by 1361
Abstract
Freshwater resources that humans can use directly account for 2.5 percent. Fog collection from the atmosphere is an eco-friendly and potential solution to the water shortage crisis. This study presents a biomimetic approach to fog collection inspired by the Namib Desert beetle and [...] Read more.
Freshwater resources that humans can use directly account for 2.5 percent. Fog collection from the atmosphere is an eco-friendly and potential solution to the water shortage crisis. This study presents a biomimetic approach to fog collection inspired by the Namib Desert beetle and cacti. Using fused deposition modeling (FDM) 3D printing and atmospheric pressure plasma (APP) treatment, we fabricated hybrid wettability surfaces combining hydrophobic polypropylene (PP) and super hydrophilic polycarbonate (PC). These surfaces significantly improved fog collection efficiency, achieving 366.2 g/m2/h rates by leveraging the Laplace pressure gradient and hybrid wettability gradient. This work provides an efficient and effective methodology to fabricate hybrid wetting surfaces and can be potentially applied to fog harvesting and microfluidic devices. Full article
(This article belongs to the Section Biomimetic Surfaces and Interfaces)
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17 pages, 7656 KiB  
Review
Supramolecular Adhesives Inspired by Nature: Concept and Applications
by Abhishek Baral and Kingshuk Basu
Biomimetics 2025, 10(2), 87; https://doi.org/10.3390/biomimetics10020087 - 1 Feb 2025
Cited by 2 | Viewed by 1172
Abstract
Supramolecular chemistry, a relatively newly grown field, has emerged as a useful tool to fabricate novel smart materials with multiple uses. Adhesives find numerous uses, from heavy engineering to biomedical science. Adhesives are available in nature; inspired by them and their mechanism of [...] Read more.
Supramolecular chemistry, a relatively newly grown field, has emerged as a useful tool to fabricate novel smart materials with multiple uses. Adhesives find numerous uses, from heavy engineering to biomedical science. Adhesives are available in nature; inspired by them and their mechanism of adhesion, several supramolecular adhesives have been developed. In this review, supramolecular chemistry for the design and fabrication of novel adhesives is discussed. The discussion is divided into two segments. The first one deals with key supramolecular forces, and their implication is designing novel adhesives. In the second part, key applications of supramolecular adhesives have been discussed with suitable examples. This type of review casts light on the current advancements in the field along with the prospects of development. Full article
(This article belongs to the Special Issue Adhesives Inspired by Nature: When Bionics Boost Adhesive Innovation)
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15 pages, 8962 KiB  
Article
Mantises Jump from Smooth Surfaces by Pushing with “Heel” Pads of Their Hind Legs
by Hanns Hagen Goetzke, Malcolm Burrows and Walter Federle
Biomimetics 2025, 10(2), 69; https://doi.org/10.3390/biomimetics10020069 - 22 Jan 2025
Cited by 2 | Viewed by 1175
Abstract
Juvenile mantises can jump towards targets by rapidly extending their middle and hind legs. Here, we investigate how mantises can perform jumps from smooth surfaces such as those found on many plants. Stagmomantis theophila mantises possess two distinct types of attachment pads on [...] Read more.
Juvenile mantises can jump towards targets by rapidly extending their middle and hind legs. Here, we investigate how mantises can perform jumps from smooth surfaces such as those found on many plants. Stagmomantis theophila mantises possess two distinct types of attachment pads on each foot: three small proximal euplantulae (“heel pads”) with microscopic cuticular ridges and one smooth large distal pair of euplantulae (“toe pad”). Microscopy showed that the surface contact of heel pads is strongly load-dependent; at low normal forces, they make only partial surface contact due to the ridges, but at higher loads they switch to larger areas in full contact. By analysing the kinematics of 64 jumps of 23 third-instar nymphs from glass surfaces and the foot contact areas of their accelerating legs, we show that heel and toe pads fulfil distinct roles. During the acceleration phase of jumps, the contact area of the hind legs’ heel pads tripled, while that of the toe pad decreased strongly, and the toe pad sometimes detached completely before take-off. Although the middle legs also contribute to the jump, they showed a less consistent pattern; the contact areas of their heel and toe pads remained largely unchanged during acceleration. Our findings show that jumping mantises accelerate mainly by pushing with their hind legs and produce grip on smooth surfaces primarily with the heel pads on their proximal tarsus. Full article
(This article belongs to the Special Issue Biological Attachment Systems and Biomimetics)
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19 pages, 5962 KiB  
Article
The Effect of Lipopolysaccharides from Salmonella enterica on the Size, Density, and Compressibility of Phospholipid Vesicles
by Tamás Szabó, Zuzana Garaiová, Sopio Melikishvili, Marek Tatarko, Zsófia Keresztes and Tibor Hianik
Biomimetics 2025, 10(1), 55; https://doi.org/10.3390/biomimetics10010055 - 15 Jan 2025
Cited by 1 | Viewed by 1018
Abstract
The properties of the large unilamellar vesicles (LUVs) from 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC), modified by lipopolysaccharides (LPS) from Salmonella enterica sv. Enteritidis, which mimics Gram-negative bacteria, were studied by various physical methods. LPS, in the range of 0/20/50 % w/w relative to the [...] Read more.
The properties of the large unilamellar vesicles (LUVs) from 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC), modified by lipopolysaccharides (LPS) from Salmonella enterica sv. Enteritidis, which mimics Gram-negative bacteria, were studied by various physical methods. LPS, in the range of 0/20/50 % w/w relative to the lipid, had a regulatory role in the structure of the LUVs toward the lower size, low polydispersity, and over-a-month size stability due to the lower negative zeta potential. The addition of LPS resulted in increased density, which determined the ultrasound velocity and the specific adiabatic compressibility. In a 0.5/1/2 mg/mL concentration range, the total lipid content did not significantly affect the size of LUVs and influenced the density-related attributes similarly to the LPS content. A positive correlation was found between temperature and vesicle size, and a negative correlation was found between temperature and density and compressibility—except for the anomaly behavior at 25 °C, around the melting point of DMPC. Full article
(This article belongs to the Section Biomimetic Surfaces and Interfaces)
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