Universal Influenza Vaccines for Humans and Animals

Dear Colleagues,

Seasonal epidemics and occasional pandemics highlight the major public health burden of influenza virus infections in the human population. In addition, influenza outbreaks in a wide range of animal species present a threat to domestic and wild animal well-being and food security. Vaccination is universally accepted as the most effective way to prevent influenza infections. However, the ever-changing nature of these viruses, which mutate through antigenic drift and/or shift, results in escape from earlier immune responses and the need for vaccine reformulation and re-vaccination. Universal vaccine efforts tackling these challenges attempt to improve the strength and/or breadth of the immune response. Outstanding questions include how different vaccines modulate mucosal, humoral and cellular responses, the duration of immunity after vaccination, quality and/or quantity of protective immune responses and the establishment of methods to better understand correlates of protection. This Special Issue is dedicated to novel and/or improved vaccine technologies, manufacturing tools and alternative methods to measuring immune responses to establish more effective universal vaccines and universal platforms to prevent influenza infections in humans and animals. I encourage you to take advantage of this opportunity to highlight your influenza vaccine research.

Dr. Daniel R Perez
Guest Editor

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