Inflammatory Breast Cancer in Dogs
A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Anatomy, Histology and Pathology".
Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 1122
Special Issue Editors
Interests: cancer endocrinology; cancer metastasis; reproductive endocrinology; tumors; endocrine disruption; lymphangiogenesis; xenograft model; hormonal analysis; comparative endocrinology; canine and human inflammatory breast cancer; angiogenesis processes
Special Issues, Collections and Topics in MDPI journals
Interests: histology; pathological anatomy; comparative oncology; endocrinology; domestic and wild animals
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
It is well known that canine inflammatory mammary carcinoma (IMC) is the most malignant of all mammary cancer categories because of its non-negligible invasiveness. IMC has a rapid progression, a high malignancy, and a poor prognosis. Therefore, a comprehensive assessment of the extent of tumor spread and metastasis is very important to determine the treatment plan.
Canine inflammatory mammary carcinoma can be broadly classified into primary and secondary surnames. The average age of canine disease is 10–11 years. Because these tumors are highly metastatic (e.g., in the lymph nodes and lungs), many affected dogs already have other metastatic conditions when they are first diagnosed. Postoperative inflammatory mammary carcinoma is the most difficult to deal with among secondary inflammatory mammary carcinomas. The prognosis for this type of mammary cancer is extremely poor, with dogs surviving on average less than 2 months. Therefore, inflammatory mammary carcinoma is a fatal high-risk disease for dogs.
Furthermore, canine inflammatory mammary carcinoma (IMC) shares similar histopathological, molecular, and clinical features with human inflammatory breast cancer (IBC). Previously, we routinely used rodent cancer models to decipher human cancer biology. However, there are many limitations when it comes to translating conclusions into practical diagnosis and treatment methods. Currently, as canines are a unique animal species, the natural canine model of the disease is more suitable as a natural model of human inflammatory breast cancer (IBC).
We hope that through this exchange, we can better understand the methods and techniques for canine inflammatory mammary carcinoma diagnosis and explore more effective interventions for the disease.
We sincerely invite you to share your latest discoveries in this Special Issue.
Dr. Sara Cristina Caceres Ramos
Dr. Paloma Jimena De Andrés Gamazo
Guest Editors
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Keywords
- canine
- dogs
- inflammatory mammary carcinoma
- breast cancer
- histopathological
- clinical
- immunohistochemistry
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