Neurotoxicity from Exposure to Environmental Pollutants
A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Neurotoxicity".
Deadline for manuscript submissions: closed (31 March 2026) | Viewed by 2876
Special Issue Editors
Interests: fluoride; polybrominated biphenyl ethers; persistent organic pollutant; emerging contaminants; developmental neurotoxicity; mitochondrial dysfunction; neurodegenerative diseases; molecular mechanisms; intervention strategies
Interests: lead; neurotoxicity; persistent organic pollutant; emerging contaminants; molecular mechanisms; computational toxicology; CRISPR-Cas9 gene editing
Special Issue Information
Dear Colleagues,
Neurotoxicity resulting from exposure to environmental pollutants presents a growing public health concern, as many chemicals used in industry, agriculture, and consumer products have the potential to impair nervous system function. Advances in mechanistic research reveal how various pollutants—such as heavy metals, pesticides, air particulates, endocrine disruptors, and emerging contaminants—interact with neural tissues, disrupting cellular processes, synaptic transmission, and neurodevelopment. Understanding these complex interactions requires integrative approaches that encompass chemical, biological, physical, and social determinants of health. Developing predictive models is essential for estimating neurotoxic risks across diverse populations and exposure scenarios. Such models leverage computational tools, including machine learning, systems biology, and data integration techniques, to handle vast and heterogeneous data streams. Enhancing data-sharing platforms, standardizing protocols, and developing user-friendly visualization tools foster collaboration and enable more accurate risk characterization. Transdisciplinary efforts are shifting the focus from reactive toxicity testing to proactive exposure monitoring and early intervention strategies.
In this Special Issue, we highlight innovative methodologies to elucidate neurotoxic mechanisms, improve exposure assessment accuracy, and support policy decisions aimed at reducing neurotoxic risks from environmental pollutants, ultimately protecting neurological health across the lifespan. Topics of interest include, but are not limited to, the following:
- Mechanisms of neurotoxicity;
- Exposure assessment and precision monitoring technologies;
- Cross-scale predictive modeling and computational toxicology;
- Health risk assessment and policy support tools;
- Prevention strategies and transdisciplinary solutions.
Prof. Dr. Shun Zhang
Guest Editor
Dr. Fang Ye
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- neurotoxicity mechanisms
- environmental pollutants
- emerging contaminants
- exposure assessment
- computational toxicology
- predictive modeling
- risk characterization
- early intervention strategies
- transdisciplinary approaches
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