Neurotoxicity from Exposure to Environmental Pollutants

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Neurotoxicity".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 9

Special Issue Editors


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Guest Editor
Department of Occupational and Environmental Health, MOE Key Laboratory of Environment and Health, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Interests: fluoride; polybrominated biphenyl ethers; persistent organic pollutant; emerging contaminants; developmental neurotoxicity; mitochondrial dysfunction; neurodegenerative diseases; molecular mechanisms; intervention strategies

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Guest Editor Assistant
Department of Occupational and Environmental Health, MOE Key Laboratory of Environment and Health, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Interests: lead; neurotoxicity; persistent organic pollutant; emerging contaminants; molecular mechanisms; computational toxicology; CRISPR-Cas9 gene editing

Special Issue Information

Dear Colleagues,

Neurotoxicity resulting from exposure to environmental pollutants presents a growing public health concern, as many chemicals used in industry, agriculture, and consumer products have the potential to impair nervous system function. Advances in mechanistic research reveal how various pollutants—such as heavy metals, pesticides, air particulates, endocrine disruptors, and emerging contaminants—interact with neural tissues, disrupting cellular processes, synaptic transmission, and neurodevelopment. Understanding these complex interactions requires integrative approaches that encompass chemical, biological, physical, and social determinants of health. Developing predictive models is essential for estimating neurotoxic risks across diverse populations and exposure scenarios. Such models leverage computational tools, including machine learning, systems biology, and data integration techniques, to handle vast and heterogeneous data streams. Enhancing data-sharing platforms, standardizing protocols, and developing user-friendly visualization tools foster collaboration and enable more accurate risk characterization. Transdisciplinary efforts are shifting the focus from reactive toxicity testing to proactive exposure monitoring and early intervention strategies.

In this Special Issue, we highlight innovative methodologies to elucidate neurotoxic mechanisms, improve exposure assessment accuracy, and support policy decisions aimed at reducing neurotoxic risks from environmental pollutants, ultimately protecting neurological health across the lifespan. Topics of interest include, but are not limited to, the following:

  • Mechanisms of neurotoxicity;
  • Exposure assessment and precision monitoring technologies;
  • Cross-scale predictive modeling and computational toxicology;
  • Health risk assessment and policy support tools;
  • Prevention strategies and transdisciplinary solutions.

Prof. Dr. Shun Zhang
Guest Editor

Dr. Fang Ye
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neurotoxicity mechanisms
  • environmental pollutants
  • emerging contaminants
  • exposure assessment
  • computational toxicology
  • predictive modeling
  • risk characterization
  • early intervention strategies
  • transdisciplinary approaches

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Published Papers

This special issue is now open for submission.
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