Effects and Mechanism of Endocrine Disruption and Reproductive Abnormality of Emerging Pollutant
A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Reproductive and Developmental Toxicity".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 56
Special Issue Editors
Interests: cardiovascular disease; heath risk; endocrine disrupting chemicals; biological mechanism; nuclear receptor pathway
Special Issues, Collections and Topics in MDPI journals
Interests: environmental pollution; PFAS; fertilization toxicity; neurotoxicity; immunotoxicology
Interests: computational toxicology; theoretical environmental chemistry; toxicity prediction based on machine learning; adverse outcome pathway; interaction between chemicals and nuclear receptors
Interests: endocrine disrupting chemicals; female reproductive health; in vitro reproductive models; ovarian toxicity; folliculogenesis
Special Issue Information
Dear Colleagues,
Endocrine-disrupting chemicals (EDCs) are widespread exogenous chemicals that can interfere with hormone action and increase the adverse health risks of organisms, including endocrine system disruption, reproductive abnormality, and development impairment. The mechanisms by which biomacromolecule and EDCs exert specific actions have continuously deepened and can provide holistic understandings of adverse endocrine disruption evidence. The Special Issue examines the endocrine-disrupting and reproductive health effects and the potential mechanisms induced by EDC exposure.
The Special Issue focuses on understanding the mechanisms of EDCs’ actions regarding health effects via in vitro, in vivo, and in silico studies, including original articles or reviews. Topics include, but are not limited to, the following examples: (1) investigations of the endocrine disruption or reproductive abnormality of EDCs at various biological levels from molecular mechanisms to health impacts; (2) the determination of the level or dose of EDCs that can induce endocrine disruption; (3) toxicity predictions and mechanism analyses of EDCs utilizing integrated methods of computational toxicology, including molecular simulations and machine learning; (4) the screening and validation of the key biomolecules of EDC-indcued toxic effects based on multi-omics technology; and (5) nuclear receptor-mediated adverse outcomes.
Dr. Liping Lu
Dr. Yu Han
Dr. Shixuan Cui
Dr. Tingjie Zhan
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- environmental toxicology
- endocrine disruption
- molecular mechanism
- emerging pollutants
- nuclear receptor
- computational toxicology
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