Innovative Separation Strategies for Bioactive Compounds from Plants: Methods, Mechanisms, and Applications

A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Analysis of Natural Products and Pharmaceuticals".

Deadline for manuscript submissions: 10 May 2026 | Viewed by 8

Special Issue Editors


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Guest Editor
Integrated Multiuser Laboratory in Applied Biotechnology (LIBAS), Institute of Biological Sciences, University of Pernambuco (UPE), Rua Arnóbio Marques, Recife 50100-130, Brazil
Interests: biochemistry; biotechnology; protein purification; enzyme and protease inhibitors; clinical and experimental microbiology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Biological Science Institute, University of Pernambuco, Recife, Brasil
Interests: biochemistry; biotechnology; protein purification; enzyme and protease inhibitors; clinical and experimental microbiology

Special Issue Information

Dear Colleagues,

The study of plant-derived bioactive compounds has gained significant attention due to their wide range of biological properties and potential applications in pharmaceuticals, nutraceuticals, cosmetics, and functional foods. However, the efficient separation, purification, and characterization of these compounds remains challenging due to their structural diversity, low abundance, and the complexity of plant matrices. This Special Issue aims to highlight recent advances and innovative methodologies in the separation of bioactive phytochemicals, including cutting-edge chromatographic techniques, membrane-based processes, solid-phase extraction, green and sustainable approaches, and integrated analytical platforms. Contributions focusing on methodological developments, process optimization, mechanistic understanding, and novel applications in biological systems are all welcome. Both experimental and theoretical studies that enhance our understanding of separation science applied to plant bioactives will be considered. By bringing together state-of-the-art research and technological innovations, this Special Issue seeks to foster interdisciplinary collaboration and accelerate the translation of separation science into real-world biological and industrial applications.

Prof. Dr. Romero M. P. Brandão-Costa
Dr. Daniela A. Viana Marques
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant-derived bioactives
  • phytochemical separation
  • chromatographic techniques
  • green extraction methods
  • membrane separation
  • natural products purification
  • bioactive compounds characterization
  • sustainable separation technologies
  • phytopharmaceuticals
  • functional plant ingredients

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Published Papers

This special issue is now open for submission.
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