Design and Development of Enzymatic Biosensors
A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Sensor Materials".
Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 214
Special Issue Editors
Interests: enzyme immobilization and stabilization; biosensors; biocatalysis; protein–polymer conjugates; protein engineering
Special Issue Information
Dear Colleagues,
Since the inception of the glucose biosensor, there has been significant hope for enzymatic biosensors to fulfill many analytical needs in areas such as field analysis for environmental monitoring, point-of-care testing in medicine, and real-time process monitoring in the food and biologics industries. With the rapid growth in supporting fields such as material science, protein engineering, and nanofabrication, almost every aspect of an enzyme-based sensor can be improved. However, developing a practical biosensor remains a challenge because the development process involves integration of many desirable features, such as sensitivity, response time, shelf-life, simplicity of use, form factor, and cost. A developer has to prioritize options at every step of the design process, since it is impractical to evaluate them all. Very few sensors have reached the stage where they can be practically field-tested, and even fewer have been evaluated by proper planning and execution. The objectives of this Special Issue are to report the state-of-the-art in enzyme-based biosensor development, showcasing the integration of desirable features in a sensor product, and harmonizing the evaluation process for sensor product development.
Topics of interest include but are not necessarily limited to the following:
- Bioreceptor (enzyme) selection, design, and engineering
- Signal transduction for biosensors
- Sensing principles and proof of concept
- Sensor prototype development
- Fabrication technology for biosensors
- Sampling and sample preparation for biosensors
- Characterization and validation of biosensors
- Field testing and validation
- Biosensor device design and reagent formulation
- Application of biosensors for environment monitoring, point-of-care tests in medicine or other urgent decision-making needs
- Data quality and analysis for biosensors
- Guidelines for reporting sensor development data
Dr. Jason Berberich
Dr. Tao Li
Guest Editors
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Keywords
- enzyme sensor;
- sensor design;
- sensor fabrication;
- assay protocol;
- signal transduction;
- sensor characterization;
- field test
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