Artificial Intelligence in Mental Health and Psychiatry: Methods, Applications and Implications

Special Issue Editor


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Guest Editor
Clinical Epidemiology Laboratory, Faculty of Nursing, National and Kapodistrian University of Athens, 11527 Athens, Greece
Interests: public health; research methodology; epidemiology; evidence-based nurse

Special Issue Information

Dear Colleagues,

We are pleased to invite you to this Special Issue, which brings together cutting‑edge research at the intersection of AI, mental health and psychiatry. This Special Issue aims to showcase rigorous methodological innovations, real‑world clinical applications and multidisciplinary perspectives on the opportunities and challenges of AI‑enabled mental healthcare. We invite original contributions that advance scientific knowledge, address implementation barriers and critically examine the broader implications of AI for clinicians, patients, researchers and society.

This Special Issue serves as an international, interdisciplinary forum that brings together computer scientists, clinicians, mental health professionals, social scientists, ethicists and policymakers. Our scope is to foster evidence‑based discussion, highlight innovative solutions and advance responsible, human‑centered AI that enhances—rather than replaces—the expertise of mental health professionals.

Themes and topics of interest

We welcome research articles and systematic reviews. Submissions may include—but are not limited to—the following areas:

  1. Methodological Advances
  • Machine learning, deep learning and natural language processing for psychiatric research
  • Explainable and interpretable AI models in mental healthcare
  • Digital phenotyping, behavioral markers and passive sensing
  • Federated learning, privacy‑preserving analytics and secure data architectures
  1. AI for clinical decision support
  • AI‑based tools for diagnosis, prognosis and risk stratification
  • Early detection of depression, anxiety, psychosis, bipolar disorder, dementia and other conditions
  • Predictive models for suicide risk and crisis prevention
  • Tailored treatment planning, medication optimization and clinical outcome prediction
  1. Therapeutic and intervention applications
  • AI‑enhanced psychotherapeutic tools and digital therapeutics
  • Monitoring and supporting patient adherence, engagement and symptom tracking
  • Precision psychiatry and individualized treatment pathways
  1. Implementation science and real‑world evaluation
  • Clinical validity, reliability and generalizability of AI models
  • Integration of AI into clinical workflows and electronic health systems
  • Human–AI collaboration in mental health care
  • Barriers to adoption, including training, usability and regulatory factors
  • Attitudes towards AI chatbots for mental health support
  1. Ethical, legal and societal implications
  • Bias, fairness and health equity in AI-driven psychiatric tools
  • Transparency, accountability and responsible innovation
  • Patient autonomy, consent and data governance
  • Implications of AI for the therapeutic relationship and clinical judgment

Dr. Aglaia Katsiroumpa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Psychiatry International is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • artificial intelligence
  • mental health
  • psychiatry
  • chatbots
  • applications
  • patients
  • barriers
  • implications
  • treatment pathways
  • monitoring

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Published Papers

This special issue is now open for submission.
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