Advancements in Biopolymers for Tissue Engineering: Innovations, Challenges and Future Directions
A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biobased and Biodegradable Polymers".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 31
Special Issue Editor
Special Issue Information
Dear Colleagues,
Tissue engineering holds immense promise for regenerative medicine, offering the potential to repair or replace damaged tissues and organs. Biopolymers, derived from natural sources or synthesized to mimic natural components, are central to this field. Their biocompatibility, biodegradability, and tuneable mechanical and physico-chemical properties make them ideal for creating scaffolds, hydrogels, and drug delivery systems that support cell growth and tissue regeneration. This Special Issue of Polymers focuses on the latest advancements in biopolymers for tissue engineering, exploring innovative approaches, addressing key challenges, and outlining future research directions.
This Special Issue invites contributions that showcase cutting-edge research and development in the use of biopolymers for tissue engineering applications. We welcome original research articles, comprehensive reviews, and insightful perspectives covering a wide range of topics, including, but not limited to, the following:
- Novel Biopolymer Synthesis and Modification: The development of new biopolymers and modification strategies to enhance their bioactivity, mechanical properties, and degradation profiles.
- Advanced Scaffold Fabrication Techniques: Innovative methods for creating 3D biopolymer scaffolds, such as 3D bioprinting, electrospinning, and microfluidic approaches.
- Biopolymer-Based Hydrogels: The design and application of hydrogels for cell encapsulation, controlled drug release, and as injectable biomaterials.
- Cell–Biopolymer Interactions: Studies investigating the influence of biopolymer properties on cell adhesion, proliferation, differentiation, and tissue formation.
- In Vitro and In Vivo Evaluation: Assessment of the biocompatibility, biodegradability, and regenerative potential of biopolymer-based constructs in preclinical models.
- Clinical Translation: Exploration of the clinical applications of biopolymers in tissue engineering, including case studies and clinical trials.
- Bioinks for 3D Bioprinting: Development and characterization of biopolymer-based bioinks for creating complex tissue structures.
- Nanobiomaterials for Tissue Engineering: Integration of nanotechnology with biopolymers to enhance tissue regeneration.
- Drug and Gene Delivery Systems: Biopolymer carriers for controlled release.
The above list is only indicative and by no means exhaustive. Any original theoretical, simulation, experimental work or review article on advancements in biopolymers for tissue engineering is welcome.
We encourage submissions that address challenges in translating biopolymer-based technologies from the laboratory to the clinic, and those that explore the future potential of biopolymers in regenerative medicine. Furthermore, we aim to provide a comprehensive overview of the current state-of-the-art and to stimulate further innovation in this rapidly evolving field. We look forward to your contributions.
Dr. Monica B. Mathor
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biopolymers
- tissue engineering
- scaffolds
- hydrogels
- 3D bioprinting
- regenerative medicine
- biocompatibility
- biodegradability
- drug delivery
- stem cells
- biofabrication
- biomaterials
- cell–material interactions
- in vitro
- in vivo
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