Human Infectious Diseases Pathogenesis: Advanced Research on Host–Pathogen Interactions
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: 30 September 2026 | Viewed by 97
Special Issue Editor
Special Issue Information
Dear Colleagues,
Microorganisms (viruses, bacteria, fungi, and parasites) hijack host cellular pathways for replication, reproduction, and eventual release. These complex virus–host interactions are the primary determinants of the overall severity of the resulting disease. Different pathogens alter host functions related to membrane remodeling, vesicular trafficking, autophagy, lipid metabolism, RNA processing, and protein quality control, causing inflammation, immunological responses, cell death, and, in some cases, promoting cancer development.
The study of the mechanisms underlying host–pathogen interactions is critical for fighting infectious diseases, developing effective treatments, and implementing preventive strategies. Host-directed antimicrobial strategies represent a highly promising therapeutic approach for infectious diseases. For this reason, the comprehension of the complex mechanisms acting at the cell level has a pivotal role.
This Special Issue aims to increase knowledge on mechanisms through which pathogens establish infections, evade immune responses, and inflict damage upon host cells. Contributions that include in vitro, in vivo, and translational studies are welcome.
This Special Issue welcomes a variety of manuscript types, including original research papers, reviews, opinions, perspectives, case reports and brief reports.
I look forward to your valuable contributions that will promote further developments in this field.
Thank you for your collaboration.
Dr. Laura Falasca
Guest Editor
Manuscript Submission Information
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Keywords
- host–pathogen interactions
- infectious diseases
- microbial pathogenesis
- viral infections
- cell organelles modifications
- tissue/organ pathology
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