Enteroviruses: Up-to-Date Pathogenesis, Treatment, Prevention, Rapid Diagnosis, and Vaccine Development

Dear Colleagues,

Enteroviruses are small and positive-sense RNA viruses, including poliovirus, Coxsackie A virus, Coxsackie B virus, echovirus, and other enteroviruses (EVD68~), which are the most widespread serious and fatal diseases (aseptic meningitis). Pathogens of neonatal sepsis include diseases of advanced vertebrates including humans, encephalitis, acute flaccid paralysis (AFP), nonspecific febrile diseases, hand-foot-and-mouth disease (HFMD), herpetic angina, pleural pain, pericarditis and myocarditis. Enteroviruses are found in the gastrointestinal tract (the feces of infected people, the mouth) and the respiratory tract (such as saliva, sputum or nasal mucus). Direct contact with an infected person’s secretions or contaminated surfaces or objects may cause infection. Neonatal infections can also be obtained vertically from the mother who infects the mother in the womb or at the time of delivery. Humans appear to be the only known host and source of enterovirus transmission. The importance of enteroviruses in human health and the limited intervention strategies that combat enterovirus infections make it urgent to better understand the molecular and biological characteristics of these viruses and to develop effective strategies to prevent them from infecting humans. The purpose of this Special Issue is to provide a solid foundation for the latest discoveries in enterovirus research, including viral molecular and structural biology, viral–host interactions, viral pathogenesis, antiviral strategies, and vaccine development.

Dr. Robert Yung Liang Wang
Guest Editor

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