Membrane-Associated Virus-Host Interaction in Infection and Innate Immunity

Dear Colleagues,

The biological membrane is in all cells and all over the cells. It separates the interior of the cell from the outside environment, encases the cell organelles, and regulates the transport of materials in and out mainly by the membrane trafficking system. As obligate intracellular parasites, viruses are dependent on the host membrane trafficking types of machinery for almost every step during their life cycles. Now there are no specific treatments or protections for most viruses, mainly because of the limited knowledge of viral life cycles, especially the membrane-associated events and factors during these processes. The overarching goal of this issue is to define the membrane-associated virus–host interactions in infection and innate immunity.

A better understanding of this field is critical to lead to the development of novel and effective approaches to prevent or treat viral diseases. More importantly, as has been historically the case for many viruses, studies in membrane-associated virus–host interactions will provide us important new insights into immunology, oncology, cell biology, and biochemistry with implications far beyond virology.

I would like to invite colleagues investigating any of the viral interactions with their hosts, especially those happening on the biological membranes, to submit their manuscripts to this Special Issue in the form of original research and reviews.

Dr. Jian Xie
Dr. Pengwei Zhang
Guest Editors

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