Acinetobacter Pathogenesis: From Bench to Bedside
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".
Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 304
Special Issue Editor
2. CIBER of Infectious Diseases-CIBERINFEC, Instituto de Salud Carlos III, 28029 Madrid, Spain
Interests: antimicrobial resistance; foodborne pathogens; food safety; one health
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Acinetobacter baumannii cause various human infections, including pneumonia, bacteremia, wound infections, meningitis and urinary tract infections. Acinetobacter species are inherently resistant to several antibiotics and capable of readily acquiring resistance, and clinical isolates can rapidly spread among patients and survive in the hospital environment. In addition to A. baumannii, other bacteria of the genus, such as A. pittii, are arousing interest among the medical and scientific community due to the increase in the isolation of strains as well as their resistance to conventional antibiotics. It is also of interest to know the origin and possible reservoirs of the bacterium both in natural hosts and in the environment, and the routes of transmission from these environments to humans.
As recent insights into molecular mechanisms of the host-pathogen interaction in Acinetobacter spp. show that host responses from professional phagocytes mainly contribute to the exacerbation of disease, an improved understanding of these responses in the laboratory is beginning to bridge the gap between bench and bedside. In addition, cellular microbiology and in vivo models used to study these pathogens have begun to shed light on the true causes of the virulence of these bacteria.
This Special Issue will present new evidence explaining the pathogenesis of Acinetobacter, explore new findings explaining transmission and infections in different types of patients in hospital settings and discuss the challenges and opportunities for research in the field of this genus.
Dr. José Ramos-Vivas
Guest Editor
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Keywords
- Acinetobacter
- pathogenesis
- cellular microbiology
- host-pathogen interactions
- bacterial virulence
- antimicrobial resistance
