From Whisper to Resistance: Bacterial Dialogues Behind Biofilm
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 7
Special Issue Editor
Special Issue Information
Dear Colleagues,
Biofilms represent some of the most complex and resistant forms of microbial life, shaped by sophisticated communication networks that range from subtle chemical signals to coordinated actions of resistance. These interactions between bacteria, which are mainly regulated through quorum sensing, are responsible for the structural and functional diversity within biofilms, as well as for their remarkable capacity to resist antibiotics and evade host immune defences.
Far from being passive cell aggregates, biofilms are dynamic communities where bacteria exchange signals, share nutrients, and adapt collectively to environmental and host-related stress. Since biofilm development is closely controlled by quorum sensing, interfering with this bacterial communication is now seen as a promising strategy to control bacterial pathogenicity and combat antimicrobial resistance.
This Special Issue presents recent research and reviews on the molecular communication involved in the formation, maintenance, and adaptation of biofilms. We encourage readers to view biofilms not as passive structures, but as active and interactive systems that play a key role in infectious diseases. We hope this collection inspires new research and innovative solutions to the serious challenges derived from biofilm-associated infections in both medical and environmental contexts.
Dr. Andrea Muras
Guest Editor
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Keywords
- quorum sensing
- quorum quenching
- quorum sensing inhibition
- biofilm
- bacterial communities
- pathogens
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