Glial Dynamics in Neurological Disorders: From Molecular Mechanisms to Therapeutic Perspectives
A special issue of Neuroglia (ISSN 2571-6980).
Deadline for manuscript submissions: 29 June 2026 | Viewed by 3739
Special Issue Editors
2. Psychology Department, Universidad Iberoamericana, Mexico City 01376, Mexico
Interests: glia; astrocytes; microglia; oligodendrocytes; neurodegeneration; neuroinflammation; neurovascular coupling; extracellular matrix; synaptic plasticity; therapeutic targets
Interests: glial biology; cerebellum; epilepsy and neuroinflammation
Special Issue Information
Dear Colleagues,
Glial cells have emerged as central players in the pathophysiology of neurological disorders, challenging the traditional neuron-centric view of brain function and disease. This Special Issue aims to showcase cutting-edge research that illuminates the multifaceted roles of astrocytes, microglia, and oligodendrocytes in neurological conditions ranging from neurodegenerative diseases to neurovascular disorders.
We invite original research articles, comprehensive reviews, and perspectives that address the molecular, cellular, and systems-level contributions of glia to neurological health and disease. Topics of particular interest include:
- Microglial activation and neuroinflammatory cascades in neurodegenerative diseases (Alzheimer's disease, Huntington's disease, Parkinson's disease);
- Astrocytic dysfunction in epilepsy, stroke, and neurovascular malformations;
- Oligodendrocyte biology and myelin dynamics in demyelinating disorders;
- Glial-neuronal interactions in synaptic plasticity and circuit remodeling;
- Extracellular matrix remodeling and glial-vascular coupling;
- Novel therapeutic strategies targeting glial dysfunction;
- Advanced methodologies for studying glial cells in health and disease.
This Special Issue seeks to foster international collaboration and bring together diverse perspectives from researchers across the Americas, Europe, and beyond. We particularly encourage submissions that integrate molecular mechanisms with translational approaches, offering new insights into how glial biology can inform therapeutic innovation.
By bridging fundamental discoveries with clinical relevance, this collection aims to advance our understanding of glial contributions to neurological disorders and identify novel targets for intervention.
Dr. Héctor Romo-Parra
Dr. Carmen Rubio
Dr. Norma Serrano-García
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Neuroglia is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- glia
- astrocytes
- microglia
- oligodendrocytes
- neurodegeneration
- neuroinflammation
- neurovascular coupling
- extracellular matrix
- synaptic plasticity
- therapeutic targets
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