Non-Coding RNA and Glioblastoma
A special issue of Non-Coding RNA (ISSN 2311-553X).
Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 519
Special Issue Editor
Interests: ncRNAs; exosomes and extracellular vesicles; tumor heterogeneity; stem cells; oncolytic virus; cancer immunotherapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Diverse species of non-coding RNAs (ncRNAs) have been implicated in mediating countless processes taking place within and between cells, both physiological and pathological. These include numerous human malignancies where ncRNAs have been shown to act in the capacity of both pro-oncogenes and tumor suppressors. The glioblastoma is a gloomy example of one of fortunately few tumors whose morbidity and survival rates have not been significantly improved in recent decades. Its location within the most vital of organs combined with infamous heterogeneity, as well as its high degree of therapy resistance, leads to therapeutic failure and all but certain mortality within a quite short period after initial diagnosis. The past 15 or so years brought about a vast amount of information regarding the role of ncRNAs in various aspects of glioblastoma. MicroRNAs, long, non-coding RNAs, and other ncRNAs have been proven to shape various phenotypes of glioblastoma cells as well as their interaction with the tumor microenvironment, and many knock-down/replacement strategies have been demonstrated as actual modifiers of therapeutic efficacy. This Special Issue on the role of ncRNAs in glioblastoma aims to provide an update on the progress in the unraveling of multiple ncRNA-mediated mechanisms focusing on the molecular intricacies as well as on their therapeutic utility.
Dr. Agnieszka M Bronisz
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- non-coding RNA
- microRNA
- long non-coding RNAs
- glioblastoma
- tumor heterogeneity
- tumor microenvironment
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