Biotechnology Applications of Extremophiles and Extremozymes
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 2
Special Issue Editor
Special Issue Information
Dear Colleagues,
Extremophiles are microorganisms that are able to grow and thrive in extreme environments such as high or low temperatures, pH, high salt concentrations, or a combination of these conditions. They are ubiquitous and belong to the Bacteria and Archaea domains. Extremophiles, compared to other microorganisms, have a distinctive molecular evolution mechanism, physiology, and biochemistry. They are unique enzymes, also called extremozymes, and are able to withstand, in terms of activity and stability, similar extreme conditions. Extremophiles are difficult to isolate under standard laboratory conditions, limiting their application in industrial biotechnology and the access to extremozymes. Novel approaches, such as functional metagenomics, high-throughput screening, and engineering biology, which have promising synthetic biological chassis, are significantly improving their applications, as well as helping to revolutionize next-generation industrial biotechnology (NGIB), making the biomanufacturing processes more efficient, robust, and cost-effective, and having a remarkable impact on the overall transition towards a more sustainable world.
The aim of this Special Issue is to report the latest advances in the discovery of novel extremophiles and extremozymes, as well as their application in NGIBs and sustainable biomanufacturing.
Dr. Max Cárdenas-Fernández
Guest Editor
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Keywords
- extremophiles
- extremozymes
- functional metagenomics
- enzyme activity screening
- synthetic biology chassis
- industrial biotechnology
- biomanufacturing
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