Lipid Bilayers: From Fundamentals to Applications in Bioengineering and Beyond

Dear Colleagues,

Lipid bilayers, essential components of biological membranes, play critical roles in cell structure and act as barriers separating cell interiors from exteriors. These bilayers have attracted considerable attention from researchers, intrigued by their intricate composition and functional significance. Investigations into lipid bilayers encompass a wide range of topics, including the fabrication of model membranes and their application in elucidating membrane dynamics as well as molecular interactions. Researchers delve into fundamental aspects such as membrane fabrication techniques, aiming to refine methodologies for creating biomimetic lipid bilayers that accurately replicate the properties of natural cell membranes and can be used to study membrane-related processes at a fundamental level.

On the other hand, practical applications of lipid bilayers abound, including, at the forefront, biosensing and drug delivery. By introducing specific molecules into lipid bilayers, scientists engineer biosensors capable of precisely detecting various biomolecules and substances, offering invaluable tools for medical diagnostics and environmental monitoring. Additionally, lipid bilayers hold great promise in drug delivery systems. Their ability to merge with cell membranes facilitates the efficient transport of therapeutic agents into target cells, enabling targeted drug delivery strategies. Researchers can finely tune lipid bilayers to control the release kinetics of drugs, enhancing treatment efficacy while minimizing adverse effects.

This Special Issue aims to cover both the fundamental and applied aspects of lipid bilayers in biological membranes. Contributions spanning fundamental studies elucidating the properties of lipid bilayers relevant to biological membranes, as well as novel or advanced applications of lipid bilayers (e.g., in biosensing and drug delivery), are welcome. We look forward to receiving your contributions to this important area of research to advance our understanding of lipid bilayers and harness their potential for addressing pressing challenges in healthcare and beyond.

Dr. Tun Naw Sut
Guest Editor

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• lipid bilayers
• biological membranes
• bilayer interfaces
• bilayer fabrication
• bilayer characterization
• bilayer application