Marine Polyphenols and Fat Dysfunction
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (31 July 2020) | Viewed by 333
Special Issue Editor
Department of Anatomy & Cell Biology, Graduate School of Medicine, Gachon University, Incheon 21936, Korea
Interests: metabolic disease; brain disease; marine drug; proteomics; genomics
Special Issue Information
Dear Colleagues,
White adipose tissue has a crucial role in regulating systemic energy homeostasis. White adipocytes not only act as a reservoir for energy storage but also sense energy demands and secrete paracrine factors to regulate other metabolic tissues, such as liver, muscle, and pancreas. However, in obesity, white adipose tissue may become dysfunctional and not expand properly to store the energy excess. On the other hand, an important secretory role of brown adipose tissue has emerged, which is consistent, to some extent, with the earlier recognition of the important secretory role of white fat. There is a growing recognition of the signaling molecules released by brown adipocytes that target sympathetic nerve endings, inflammation, vascular cells, and immune cells to promote the tissue remodeling associated with the adaptive brown adipose tissue recruitment in response to thermogenic stimuli. Among the active compounds responsible for these activities, marine polyphenols seem to play a key role in fat dysfunction. The beneficial effects of various polyphenols on different fat-associated disorders, such as obesity, hypertension, diabetes mellitus type 2, and metabolic syndrome are well known. However, little is known about fat dysfunction, such as whitening of brown fat with marine polyphenols. The study of the preventive and therapeutic mechanisms of fat dysfunction of marine polyphenols could be applied to a variety of related diseases. In this Special Issue, you are invited to submit recent advances in research of marine polyphenols in prevention, cure, and palliation of different fat-associated disorders.
Dr. Kyunghee ByunGuest Editor
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Keywords
- Polyphenol
- Fat dysfunction
- Inflammation
- White adipose tissue
- Brown adipose tissue
- Metabolic disease
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