Marine Polyketides and Their Biosynthesis

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 229

Special Issue Editor


E-Mail Website
Guest Editor
School of Pharmacy, Sungkyunkwan University, Korea
Interests: natural product chemistry; structure elucidation; chemical biology; biosynthesis; microbiology

Special Issue Information

Dear Colleagues,

Polyketides are one of the major classes of natural products which has structurally diverse subclasses such as aromatic polyketides, macrolactones, polyethers, polyenes, and decalin-containing scaffolds. Marine-derived polyketides have shown a wide range of pharmacological effects; for example, Eribulin (Halaven®) is a macrocyclic polyketide and has been used as an anticancer medication in the Europe and the U.S. since 2010. In the living organisms, polyketides are synthesized via polyketide synthases (PKSs) which are encoded in specific biosynthetic genes. Deciphering their biosynthesis is not only of high academic value, but also facilitates manipulation of the biosynthetic pathways to increase the production level of bioactive molecules and/or to modify their chemical structures for higher potency. Therefore, marine-derived polyketides have huge potentials across chemical, biological, and pharmacological disciplines.

This Special Issue will cover the characterization of structures and biosynthetic pathways of marine-derived novel polyketides, as well as their biological application. Both original research and review papers are welcome.

Prof. Dr. Chung Sub Kim
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • marine natural products;
  • polyketides;
  • structure elucidation;
  • biosynthesis;
  • marine microbes

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Published Papers

There is no accepted submissions to this special issue at this moment.
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