Novel Marine 'Talented Producers'

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Biotechnology Related to Drug Discovery or Production".

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 139

Special Issue Editors

Department of Microbial Interactions, Institute of Microbiology, Friedrich Schiller University, Jena, Germany
Interests: cell biology; physiology of the phylum Planctomycetota; microbial interactions in aquatic ecosystems
Department of Microbial Interactions, Institute of Microbiology, Friedrich Schiller University, Jena, Germany
Interests: development of genetic tools for planctomycetes; expression of planctomycetal genes in heterologous hosts; characterization of secondary metabolite-associated biosynthetic gene clusters

Special Issue Information

Dear Colleagues,

Marine microorganisms have proven to be valuable in bioprospecting studies focused on the discovery of novel small molecules with potential health-promoting properties (e.g., antibiotics). In the past, given the broad spectrum of chemically diverse compounds that arise from complex interactions in marine ecosystems, it seemed reasonable to focus primarily on fast-growing members of well-characterized phyla known to be easy to cultivate, and for which molecular biology tools are available for genetic engineering work. However, in the long term, such strategies lead to the depletion of the biosynthetic potential of well-characterized phyla, resulting in high rates of rediscovering natural products. In recent years, advanced next-generation sequencing techniques and metagenomics have provided access to the genomes of yet uncultured bacteria from poorly studied phyla that have the potential to synthesize bioactive compounds via pathways beyond classical polyketide synthases and nonribosomal peptide synthetases. Given the antibiotic crisis we currently face, the exploration of untapped biological sources for novel small molecules must begin sooner rather than later. In this Special Issue, we welcome all types of studies addressing microbial interactions involving chemical mediators and the discovery of novel natural products in marine microorganisms or those based on derived genes, as well as concerning the bioinformatic-based profiling of biosynthetic patterns of natural products, preferably from largely unexplored phyla.

Prof. Dr. Christian Jogler
Dr. Nicolai Kallscheuer
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • small molecules
  • bioactivity
  • natural products
  • unexplored phyla
  • biosynthetic gene clusters
  • microbial interactions
  • bioprospection
  • genome mining

Published Papers

There is no accepted submissions to this special issue at this moment.
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