Bioprospecting of Marine Vibrios
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (30 June 2020) | Viewed by 364
Special Issue Editor
2 Sorbonne Universités, UPMC Paris 06, CNRS, UMR 8227, Integrative Biology of Marine Models, Station Biologique de Roscoff, CS 90074, F-29688, Roscoff cedex, France
Interests: Frédérique Le Roux studies virulence evolution of pathogen in the wild. In recent years, her lab has investigated the molecular mechanisms involved in the emergence of vibrio pathogenic to marine invertebrates (oyster, shrimp and corals). These include molecular epidemiology with an emphasis on biodiversity, virulence and genome plasticity, environmental genomics, and host/pathogen interaction. More recent questions addressed by the lab are the emergence of antibiotic-resistant vibrios in aquaculture settings and the role played by the phages in the ecology and evolution of pathogenic environmental vibrios. Previously, F. Le Roux’s work was concerned with human herpes virus and carcinogenesis.
Special Issue Information
Dear Colleagues,
Vibrionaceae (or vibrios) is a family of ubiquitous heterotrophic bacteria found in aquatic environments. Although they represent a small percentage of the bacteria in these environments, vibrios can predominate during blooms and play crucial roles in biogeochemical processes. Vibrios include the human pathogens Vibrionaceae cholera, as well as other less well-characterized animal pathogens. Indeed, it is the most important bacterial group implicated in infections of marine animals and causes major economic losses in aquaculture.
As we are facing the emergence of pathogenic and/or antibiotic-resistant vibrio, eco-inspired innovative strategies to develop new effective antimicrobials are strongly encouraged. Among these strategies, the phages, the natural predators of bacteria, are strong candidates for the treatment of bacterial infections in order to limit the spread of antibiotic-resistant bacteria. Probiotic, quorum-quenching molecules, and antimicrobial peptides are also considered as alternatives to antibiotic.
While most of the research on Vibrio focuses on pathogenesis, the potential of these bacteria as a source of molecules for therapeutic or industrial applications is an emergent topic. This encompasses, for example, secondary metabolites, antimicrobial compounds, exopolysaccharides, enzymes for hydrocarbon remediation, and development of biofuels. A major gap in knowledge includes biosynthetic gene clusters, their regulation and role in the adaptation to the niche or metabolic specialization, and their acquisition and spread.
For this Special issue, we seek scientific articles, original research and opinion paper on new advances in the field of Bioprospecting of Vibrios.
Dr. Frédérique Le Roux
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- Bioactive compounds
- Phage
- Probiotic
- Antimicrobial
- Quorum quenching
- Hydrocarbon
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