Special Issue "Histo-immunology in Exercise"

A special issue of Journal of Functional Morphology and Kinesiology (ISSN 2411-5142).

Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 458

Special Issue Editor

Department of Biomedical and Biotechnological Science, University of Catania, Catania, Italy
Interests: neurodegenerative disease; bioinformatics; bhitinases; innate immunity; macrophages; dendritic cells
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Over the past years, a variety of studies have demonstrated that exercise induces a considerable physiological change in the innate and adaptive immune system.  During exercise, the blood cell population varies considerably. In particular Neutrophil concentrations increase during and after exercise, whereas lymphocyte concentrations increase during exercise and fall below pre values after long-duration physical work. These changes in the cellular component are accompanied by phenomena related to the secretion of cytokines closely linked to the muscle morpho-functional changes and the relative target organs of pro and anti-inflammatory cytokines. Furthermore, it has been shown as an acute, intense muscular exercise increases the concentrations of a number of stress hormones in the blood, including epinephrine, norepinephrine, growth hormone, b-endorphins, testosterone, estrogen, and cortisol. Without a doubt, physical exercise and sports influence the concentration of immunological cells in the circulating blood. An interesting question is,  however,  to what degree are these cellular proportion changes influence the resistance to diseases such as the seasonal flu, infectious disease (HIV, SARS-CoV), and  the those that affect the upper respiratory tract, cancer, the metabolic diseases, or aging.  Furthermore, it is worth noting the action carried out by physical exercise on the immune cell balance in patients with neurodegenerative diseases. However, there are several gaps in the literature regarding the effective role of the immuno-system during physical exercise. The purpose of this Special Issue is to deepen the existing literature on the mechanistic factors the regulate the pleiotropic action of immune cells in the human body organs during the exercise.

Prof. Dr. Michelino Di Rosa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Morphology and Kinesiology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • physical activity
  • innate immunity
  • adaptive immunity
  • Alzheimer’s Disease
  • bioinformatics
  • monocyte
  • macrophage
  • lymphocyte
  • neutrophil
  • blood
  • muscles
  • cytokines
  • HIV
  • SARS-CoV
  • cancer
  • aging
  • amyotrophic lateral sclerosis
  • multiple sclerosis
  • neurodegenerative disease
  • diabetes

Published Papers

There is no accepted submissions to this special issue at this moment.
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