Advancements in Cornea Transplantation

Dear Colleagues,

In recent years, advancements in corneal transplantation have significantly improved the outcomes and expanded the scope of this critical ophthalmic procedure. Notable developments are the evolution of lamellar procedures, such as deep anterior lamellar keratoplasty (DALK), and endothelial keratoplasty techniques, such as Descemet membrane endothelial keratoplasty (DMEK) and Descemet's stripping automated endothelial keratoplasty (DSAEK). These procedures target the replacement of specific layers of the cornea, enhancing visual recovery and reducing graft rejection.

Additionally, advancements in tissue engineering and regenerative medicine have paved the way for innovative approaches, such as bioengineered corneal tissue and the use of RHO-kinase inhibitors. These emerging technologies aim to address the limitations of traditional donor-dependent transplantation by providing alternative sources of corneal tissue. Furthermore, ongoing research focuses on refining immunosuppressive strategies to minimize graft rejection and improve long-term graft survival.

In conclusion, recent advancements in corneal transplantation encompass a spectrum of innovations, ranging from surgical techniques and technology integration to tissue engineering and immunomodulation. These advancements collectively contribute to the continued enhancement of patient outcomes and the evolution of corneal transplantation as a sophisticated and effective therapeutic modality in ophthalmology.

The aim of this Special Issue is to present original studies as well as reviews on corneal transplantation. Authors should submit articles on themes including, but not limited to, in vivo models; the evaluation of technology for the clinical assessment of corneal transplants and outcomes; improvements in the diagnosis of diseases that may lead to corneal transplantation; and transplant techniques, management, and outcomes.

You may choose our Joint Special Issue in JCM.

Dr. Giulia Coco
Dr. Davide Romano
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical & Translational Ophthalmology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• corneal transplant
• keratoplasty
• DMEK
• DSAEK
• PK
• cornea