Special Issue "Left–Right Asymmetry and Cardiac Morphogenesis"
A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425).
Deadline for manuscript submissions: closed (31 October 2017).
Interests: cardiac development; left–right development; cardiomyocyte biology; transcriptional regulation; arrhythmia
Interests: heart development; proepicardial development; left-right asymmetry; cardiac pacemaker development; popeye genes
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Journal of Cardiovascular Development and Disease (JCDD) launches a Special Issue on left–right asymmetry in cardiac morphogenesis. The mature heart is a highly asymmetric structure, which originates from symmetrically organized paired heart fields at the primitive streak stage. Asymmetry within the heart is generated by different processes, which include determination of left–right atrial identity, looping and asymmetric remodeling. These processes are globally summarised under the term “cardiac laterality”. Correct heart development crucially depends on proper establishment of its laterality and not surprisingly severe congenital cardiac pathologies can be traced back to an impairment of this process. The establishment and regulation of cardiac laterality depends on proper establishment of the left–right axis during early embryogenesis and is a complex issue, which implies the fine interplay between molecular, cellular, and biophysical processes.
This thematic issue will cover the state-of-the-art knowledge on the mechanisms establishing cardiac laterality and left–right axis formation and will offer a perspective on its impact on congenital heart disease.
Dr. Marina Campione
Prof. Dr. Thomas Brand
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- left–right axis formation
- cardiac morphogenesis
- congenital heart disease