Natural and Synthetic Products for Biological Control of Plant Diseases

A special issue of International Journal of Plant Biology (ISSN 2037-0164). This special issue belongs to the section "Plant Physiology".

Deadline for manuscript submissions: 30 August 2025 | Viewed by 581

Special Issue Editor


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Guest Editor
Instituto Federal de Educação, Ciência e Tecnologia do Triângulo Mineiro—Campus Uberlândia Centro, Uberlândia 38064-790, Brazil
Interests: natural products; organic chemistry; essential oils; biologically active compounds; agrochemistry; chemical education
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Special Issue Information

Dear Colleagues,

We would like to invite you to contribute your valuable insights and innovative findings to our upcoming Special Issue of the International Journal of Plant Biology entitled “Natural and Synthetic Products for Biological Control of Plant Diseases”. Phytopathogens are the primary infectious agents in plants and cause significant economic losses in agroindustry. Plants exposed to environmental conditions are prone to be threatened by a variety of pathogenic microorganisms, such as bacteria, viruses, nematodes and fungi, which lead to significant crop  loss. Biological control is considered a promising alternative to pesticide and plant resistance to manage plant diseases, but better understanding of the interaction of its natural and societal functions is necessary for its endorsement. The introduction of biological control agents alters interaction among plants, pathogens and environments, leading to biological and physical cascades that influence pathogen fitness, plant health and ecological function. Antifungal activity of agrochemical products is an active area of research, and extensive discovery-based research has been conducted to determine novel chemical combinations and to discover value-added roles for waste streams in plant-based industries. This Special Issue aims to cause impact by showing these compounds in processes of fungal inhibition. Papers that show the use of these compounds in plant protection formulations and the application of basic knowledge to develop innovative control strategies (e.g., biopesticides that trigger plant resistance, plants engineered to produce bioactive natural products) will be welcome. Syntheses of non-toxic bioactive molecules may also be presented.

This Special Issue promises to be an exciting platform that will showcase groundbreaking research, novel discoveries, the use of natural and synthetic products and biological control agents in crop protection and the game-changing application of natural and synthetic products.

By sharing your expertise, you will be contributing to the expansion of knowledge and the potential impact of natural and synthetic products on critical challenges to agriculture.

To our readers, we promise an insightful collection of papers that explore the vast potential of nature to advance environmental well-being. This Special Issue aims to be a reference for researchers, practitioners and policy makers who seek innovative solutions that are chemically sustainable.

Let us uncover the potential of natural and synthetic products and pave the way for a healthier and more agroecological future.

Prof. Dr. Mayker Lazaro Dantas Miranda
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Plant Biology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biocontrol agent
  • plant extract and essential oils in sustainable agriculture
  • synthesis of antimicrobial products
  • synthesis of pharmacologically active compounds
  • crop protection, pesticides and plant protection chemicals

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Published Papers (1 paper)

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Research

11 pages, 2495 KiB  
Communication
Chitosan Mitigates Phytophthora Blight in Chayote (Sechium edule) by Direct Pathogen Inhibition and Systemic Resistance Induction
by José Rigoberto Arroyo-Axol, Ana Karen Miranda-Solares, José Juan Zúñiga-Aguilar, Alma Rosa Solano-Báez, Régulo Carlos Llarena-Hernández, Luz Irene Rojas-Avelizapa and Rosalía Núñez-Pastrana
Int. J. Plant Biol. 2025, 16(3), 96; https://doi.org/10.3390/ijpb16030096 (registering DOI) - 20 Aug 2025
Abstract
Phytophthora blight, caused by Phytophthora capsici, is a destructive disease that significantly constrains the production of chayote (Sechium edule) in Mexico, leading to substantial yield and economic losses. The increasing ineffectiveness of synthetic fungicides and associated environmental concerns underscore the [...] Read more.
Phytophthora blight, caused by Phytophthora capsici, is a destructive disease that significantly constrains the production of chayote (Sechium edule) in Mexico, leading to substantial yield and economic losses. The increasing ineffectiveness of synthetic fungicides and associated environmental concerns underscore the need for sustainable control alternatives. This study evaluated the antifungal efficacy of low molecular weight chitosan (75–85% deacetylation; Sigma-Aldrich) against P. capsici under in vitro and in vivo conditions. Chitosan solutions (0.1–3.0 g L−1) were tested for their ability to inhibit pathogen growth and suppress disease symptoms. In vitro assays demonstrated a concentration-dependent inhibition of mycelial growth, with the highest dose (3.0 g L−1) reducing radial expansion by 32.6%. In fruit inoculation experiments, treatment with 1.0 g L−1 chitosan decreased lesion size by 50.9%, while the same concentration reduced disease severity index (DSI) by 50% in whole plants. Notably, symptom suppression was observed in tissues not directly exposed to chitosan, suggesting the activation of systemic resistance. Although the underlying molecular mechanisms were not directly assessed, the results support the dual role of chitosan as a direct antifungal agent and a potential inducer of host defense responses. These findings highlight the potential of chitosan as a biodegradable, low-toxicity alternative to synthetic fungicides and support its integration into sustainable management strategies for Phytophthora blight in chayote production systems. Full article
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