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IJERPH
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Evidence-Based Nursing in Primary Care: Enhancing Quality and Outcomes
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Evidence-Based Nursing in Primary Care: Enhancing Quality and Outcomes

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Care Sciences".

Deadline for manuscript submissions: 14 March 2026 | Viewed by 961

Special Issue Editors

Prof. Dr. Evridiki Kaba

E-Mail Website1 Website2
Guest Editor
Department of Nursing, University of West Attica, 12243 Athens, Greece
Interests: qualitative research; grounded theory; primary health care nursing; health promotion; basic nursing; rehabilitation nursing; evidence-based nursing; communication skills in nursing; behavioral and nutritional interventionsmmunication skills in nursing, behavioral and nutritional interventions
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Martha Kelesi

E-Mail Website
Guest Editor
Department of Nursing, University of West Attica, 12243 Athens, Greece
Interests: quantitative research; systematic reviews; primary health care nursing; health promotion; basic nursing; evidence-based nursing; health management and health economics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Evidence-Based Nursing (EBN) in primary care is a fundamental approach to improving service quality and clinical outcomes. It relies on the integration of the best available scientific evidence, clinical expertise, and patient needs, ensuring safe and effective interventions. In primary care, EBN plays a crucial role in early diagnosis, chronic disease management, and health promotion. By implementing evidence-based practices, nurses can enhance patient adherence to treatment protocols, reduce hospitalizations, and improve overall quality of life. With this, strengthening EBN in primary care leads to safer, more efficient, and patient-centered healthcare, ultimately delivering better outcomes for both patients and the healthcare system.

Prof. Dr. Evridiki Kaba
Prof. Dr. Martha Kelesi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • primary care
  • clinical outcomes
  • quality improvement
  • patient-centered care
  • chronic disease management
  • healthcare innovation
  • nursing practice
  • health promotion

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Published Papers (1 paper)

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Research

19 pages, 312 KB  
Article
Non-Adherence to Treatment Among Patients Attending a Public Primary Healthcare Setting in South Africa: Prevalence and Associated Factors
by Lucky Norah Katende-Kyenda
Int. J. Environ. Res. Public Health 2025, 22(11), 1665; https://doi.org/10.3390/ijerph22111665 - 3 Nov 2025
Viewed by 556
Abstract
In underdeveloped nations, treatment non-adherence continues to be a significant barrier to effective disease management. It has a major impact on patients and healthcare systems in public primary healthcare settings. Patients who do not take their medications as prescribed may be at higher [...] Read more.
In underdeveloped nations, treatment non-adherence continues to be a significant barrier to effective disease management. It has a major impact on patients and healthcare systems in public primary healthcare settings. Patients who do not take their medications as prescribed may be at higher risk for negative health consequences. Polypharmacy, side-effects, and drug-related problems are factors contributing to non-adherence. Additional patient-related issues include multimorbidity, lack of support, chronic-drugs, and health-literacy. The purpose of this study was to ascertain the prevalence and contributing factors of treatment non-adherence among patients presenting to a public primary healthcare setting in South Africa. Between September and October 2014, cross-sectional quantitative research using structured questionnaires was carried out with one hundred patients who were chosen using random sampling. Self-reports from patients were used to assess non-adherence to therapy. A standardized questionnaire administered by the interviewer was used to gather data, and IBM SPSS version 29 was used for analysis. Patients aged 18 years and older who were using prescribed medications were included. The characteristics of the participants were obtained using descriptive statistics, and 95% confidence intervals (CIs) are reported for Odds ratios (ORs). Associations between related factors and treatment non-adherence were obtained using the Pearson Chi-square test; a p-value of less than 0.05 was deemed statistically significant. Of the 100 patients interviewed, 35% were men and 65% women. The majority were in the age-range of 60–80 years with a high school level of education. Demographic characteristics associated with non-adherence to treatment were gender (p = 0.03) and age (p = 0.03). Chronic conditions, alcohol consumption, recreational drug use, use of medication reminders, waiting time to get treatment and support from healthcare providers all were statistically significant with p-values < 0.001, time to get to the clinic (p = 0.02), mode of transport (p = 0.01), alcohol consumption (OR 22.25 [95% CI: 8.539–57.977], p < 0.001) and recreational drug use (OR 8.73 [95% CI: 5.01–15.98], p < 0.001) were also examined. Patient medication non-adherence is a major medical problem globally. Though patient education is the key to improving compliance, use of compliance aids, proper motivation, and support are also shown to increase medication adherence. Full article
(This article belongs to the Special Issue Evidence-Based Nursing in Primary Care: Enhancing Quality and Outcomes)
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