Pathogenesis and Prevention of Substance-Use Disorders and Metabolic Syndrome
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".
Deadline for manuscript submissions: closed (10 February 2022) | Viewed by 6439
Special Issue Editor
Interests: neuroendocrine physiology; stress and addiction; diet induced obesity; type 2 diabetes; behavioral neuroscience; sex-specificity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Substance use disorders (i.e., opioid or alcohol dependency) and metabolic syndrome are distinct global public health issues that continue to prevail due to increased access to drugs of abuse, and palatable hypercaloric diets, respectively. The brain’s homeostatic centers and reward systems are involved in aspects of both substance addiction and energy homeostasis. Beyond defects in these central mechanisms, aberrations to peripheral (i.e., endocrine) systems also mediate the pathophysiology of substance use disorder, as well as clinical features of metabolic syndrome (i.e., obesity, insulin resistance). Thus, understanding common and unique mechanisms underlying the development of these diseases will provide groundwork for the development or refinement of pharmacologics with broad applications that can be further tailored for targeted diseases.
This Special Issue seeks research papers that provide insight with regard to the interplay between common and unique systems that influence vulnerability to substances of abuse and/or metabolic dysfunction. We are particularly interested in articles that report on sex-specific effects. Further, we seek original reports describing mechanisms involved in the intergenerational transmission of risk factors related to substance use disorder and/or metabolic syndrome. We encourage the submission of original basic-science, translational, and clinical-based papers produced from interdisciplinary collaborations, systematic reviews, and meta-analysis.
Dr. Anika Toorie
Guest Editor
Manuscript Submission Information
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Keywords
- Metabolic syndrome
- Substance abuse disorder
- Obesity
- Diabetes
- Epigenetics
- Neuroendocrine axes
- Addiction
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