Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.4
Journals
IJERPH
Special Issues
Decompensated Heart Failure
ijerph-logo
Submit to IJERPH Review for IJERPH Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Decompensated Heart Failure

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601).

Deadline for manuscript submissions: closed (1 February 2022) | Viewed by 8505

Special Issue Editors

Prof. Dr. Wojciech Dabrowski

E-Mail Website
Guest Editor
Anesthesiology and Intensive Care, Medical University of Lublin, 20-954 Lublin, Poland
Interests: cardiac failure; critical care; gut-heart interaction, brain-heart interaction; renal replacement therapy; levosimendan; landiolol
Prof. Dr. Agnieszka Tycińska

E-Mail Website
Guest Editor
Department of Cardiology, Medical University of Bialystok, 15-089 Bialystok, Poland
Interests: chronic kidney failure; peritoneal dialysis; hemodialysis; kidney-renal interaction; decompensated heart failure; electrocardiography
Dr. Andrzej Józef Jaroszyński

E-Mail Website
Guest Editor
Department of Nephrology, Collegium Medicum, Jan Kochanowski University of Kielce, 25-369 Kielce, Poland
Interests: anaemia; hypertension; heart failure; sudden cardiac death; hyperphosphatemia; vascular calcification; atherosclerosis; chronic kidney disease; dialysis and diabetes
Dr. Chiara Robba

E-Mail
Guest Editor
IRCCS San Martino, 16132 Genova , Italy
Interests: neurocritical care; brain ultrasonology

Special Issue Information

Dear Colleagues,

Decompensated heart failure is commonly noted in patients with critical cardiac diseases, after cardiac surgery, and in critically ill patients treated for septic shock or traumatic brain injury. A diagnosis of decompensated heart failure is mainly based on clinical examination,  haemodynamic measurement, and echocardiography. The main treatment for this pathology depends on its patomechanisms and the clinical condition. The present Special Issue is dedicated to the patomechanisms of decompensated heart failure and its treatment in patients with terminal heart failure, post-cardiosurgery cardiac failure, septic-shock-related cardiac decompensation, or traumatic brain injury-related cardiac decompensation. In this Special Issue, treatment with levosimendan and new β-blockers is also discussed. All articles are written by cardiologists, nephrologists, anesthesiologists, and/or intensivists. This Special Issue documents a multidisciplinary point of view of this dangerous-to-life pathology.

Prof. Dr. Wojciech Dabrowski
Prof. Dr. Agnieszka Tycinska
Dr. Adnrzej Jaroszynski
Dr. Chiara Robba
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • decompensated heart failure
  • microbiota
  • traumatic brain injury
  • delirium
  • renal replacement therapy
  • critically ill

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review

9 pages, 388 KiB  
Article
Norepinephrine Infusion in the Emergency Department in Septic Shock Patients: A Retrospective 2-Years Safety Report and Outcome Analysis
by Antonio Messina, Angelo Milani, Emanuela Morenghi, Elena Costantini, Stefania Brusa, Katerina Negri, Daniele Alberio, Ornella Leoncini, Silvia Paiardi, Antonio Voza and Maurizio Cecconi
Int. J. Environ. Res. Public Health 2021, 18(2), 824; https://doi.org/10.3390/ijerph18020824 - 19 Jan 2021
Cited by 6 | Viewed by 3619
Abstract
Hemodynamic optimization during sepsis and septic shock is based on a prompt and large fluid resuscitation strategy associated with early administration of norepinephrine. In our hospital, norepinephrine is administered in the emergency department (ED), within a protocol-guided management context, to reduce norepinephrine infusion [...] Read more.
Hemodynamic optimization during sepsis and septic shock is based on a prompt and large fluid resuscitation strategy associated with early administration of norepinephrine. In our hospital, norepinephrine is administered in the emergency department (ED), within a protocol-guided management context, to reduce norepinephrine infusion timing due to central line insertion. This choice, however, can be associated with side effects. Objectives: We conducted a retrospective analysis regarding the safety of norepinephrine in the ED. We also appraised the association between in-hospital mortality and predefined ED variables and patients’ admission severity scores. Design, settings, and participants: This was a retrospective analysis of electronic sheets of the ED of a tertiary hospital in the North of Italy. Outcomes measure and analysis: Electronic documentation was assessed to identify local and systemic side effects. We considered two subgroups of patients according to the in-hospital clinical paths: (1) those admitted in the intensive care unit (ICU); and (2) those who received a ceiling of care decision. We collected and considered variables related to septic shock treatment in the ED and analyzed their association with in-hospital mortality. Main Results: We considered a two-year period, including 108,033 ED accesses, and ultimately analyzed data from 127 patients. Side effects related to the use of this drug were reported in five (3.9%) patients. Thirty patients (23.6%) were transferred to the ICU from the ED, of whom six (20.0%) died. Twenty-eight patients (22.0%) received a ceiling of care indication, of whom 21 (75.0%) died. Of the 69 (54.3%) finally discharged to either medical or surgical wards, 21 (30.4%) died. ICU admission was the only variable significantly associated to in-hospital mortality in the multivariable analysis [OR (95% CI) = 4.48 (1.52–13.22); p-value = 0.007]. Conclusions: Norepinephrine peripheral infusion in the ED was associated with a low incidence of adverse events requiring discontinuation (3.9%). It could be considered safe within <12 h when a specific line management protocol and pump infusion protocol are adopted. None of the variables related to septic shock management affected in-hospital mortality, except for the patient’s ICU admission. Full article
(This article belongs to the Special Issue Decompensated Heart Failure)
►▼ Show Figures

Figure 1

Review

Jump to: Research

20 pages, 2202 KiB  
Review
Heart Metabolism in Sepsis-Induced Cardiomyopathy—Unusual Metabolic Dysfunction of the Heart
by Weronika Wasyluk, Patrycja Nowicka-Stążka and Agnieszka Zwolak
Int. J. Environ. Res. Public Health 2021, 18(14), 7598; https://doi.org/10.3390/ijerph18147598 - 16 Jul 2021
Cited by 16 | Viewed by 4232
Abstract
Due to the need for continuous work, the heart uses up to 8% of the total energy expenditure. Due to the relatively low adenosine triphosphate (ATP) storage capacity, the heart’s work is dependent on its production. This is possible due to the metabolic [...] Read more.
Due to the need for continuous work, the heart uses up to 8% of the total energy expenditure. Due to the relatively low adenosine triphosphate (ATP) storage capacity, the heart’s work is dependent on its production. This is possible due to the metabolic flexibility of the heart, which allows it to use numerous substrates as a source of energy. Under normal conditions, a healthy heart obtains approximately 95% of its ATP by oxidative phosphorylation in the mitochondria. The primary source of energy is fatty acid oxidation, the rest of the energy comes from the oxidation of pyruvate. A failed heart is characterised by a disturbance in these proportions, with the contribution of individual components as a source of energy depending on the aetiology and stage of heart failure. A unique form of cardiac dysfunction is sepsis-induced cardiomyopathy, characterised by a significant reduction in energy production and impairment of cardiac oxidation of both fatty acids and glucose. Metabolic disorders appear to contribute to the pathogenesis of cardiac dysfunction and therefore are a promising target for future therapies. However, as many aspects of the metabolism of the failing heart remain unexplained, this issue requires further research. Full article
(This article belongs to the Special Issue Decompensated Heart Failure)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop