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2nd Edition of Breast Milk and Infant Well-Being

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Children's Health".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 2246

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Guest Editor
Department of Chemistry and Immunochemistry, Wroclaw Medical University, 50-369 Wrocław, Poland
Interests: maternal-child health; perinatal period; breastfeeding and lactation; biochemistry of amniotic fluid and human milk; immunological status of human milk; metabolic syndrome
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Dear Colleagues,

The recommendation of breast milk as the best food for newborns and infants is related to its unique composition. Apart from basic nutrients, such as proteins, fats, and sugars, a mother’s milk is rich in bioactive molecules, which exhibit a wide range of biological functions. Dietary bioactive components delivered with mother’s milk benefit newborns and infants in various ways, and they are an important element of the innate immunity passed through breast milk. Bioactive milk molecules provide protection against pathogens, modulate the infant’s microbiome, and support the development and maturation of the immature immune, digestive, and nervous systems. Milk hormones—such as adiponectin, ghrelin, insulin, leptin, resistin, obestatin, apelin, and nesfatin, among others—may influence the energy balance because they can activate pathways depending on energy requirements and body stores, involved in regulating food intake. Additionally, it should be pointed out that breastfeeding provides mental and physical benefits for the mother. All these aspects play significant roles in ensuring the well-being of newborns and infants.

The rapidly rising incidence and burden of metabolic disorders worldwide is suggestive of widespread behavioural change. During infancy, there has been a shift in breastfeeding patterns due to the increased implementation of artificial milk for feeding newborns/infants, despite the overwhelming evidence-based data concerning the adverse developmental and health consequences of insufficient breastfeeding. According to the WHO, nearly two out of three infants are not exclusively breastfed for the recommended six months. The quality of the infant diet, namely breast milk, trains the immune system, has significant impacts on short- and long-term healthy development, and is an important element of metabolic programming. Moreover, among the several beneficial effects associated with breastfeeding is a decrease in the risk of development of overweight and obesity in the offspring. Nevertheless, the role of breast milk in the prevention of civilization-related diseases, such as obesity, diabetes, hypertension (metabolic syndrome), and allergies, in later life, has not been given enough attention.

Taking the above into account, there is a need to increase public awareness of the beneficial effects of breast milk on the proper physical and emotional development and well-being of infants. Therefore, the promotion of breastfeeding should be an overarching goal in public health domain.

The listed keywords suggest a few of the many related areas that are of interest for this Special Issue of IJERPH. We look forward to receiving your valuable contributions and creating a Special Issue that provides readers with the latest information concerning the impact of breast milk on infant well-being, with particular emphasis on bioactive components and metabolic programming.

Dr. Magdalena Orczyk-Pawiłowicz
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioactive milk molecules
  • breastfeeding
  • breast milk
  • healthy development and well-being
  • immunological protection
  • infant nutrition
  • innate immunity
  • metabolic programming
  • metabolic syndrome
  • milk adipokines
  • nutritional programming
  • obesity
  • gestational diabetes mellitus
  • nutritional intervention

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Published Papers (1 paper)

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Research

13 pages, 1623 KiB  
Article
Comparison of Effects of Storage at Different Temperatures in a Refrigerator, Upright Freezer on Top of Refrigerator, and Deep Freezer on the Immunoglobulin A Concentration and Lysozyme Activity of Human Milk
by Xuejing Li, Penprapa Siviroj, Jetsada Ruangsuriya, Chotiros Phanpong, Wachiranun Sirikul and Krongporn Ongprasert
Int. J. Environ. Res. Public Health 2022, 19(20), 13203; https://doi.org/10.3390/ijerph192013203 - 13 Oct 2022
Cited by 1 | Viewed by 1831
Abstract
This study aimed to investigate the effects of storing expressed human milk (HM) at different domestic storage temperatures on the secretory immunoglobulin A (SIgA) concentration and lysozyme activity. Forty mothers of full-term infants aged one to six months provided milk samples. The fresh [...] Read more.
This study aimed to investigate the effects of storing expressed human milk (HM) at different domestic storage temperatures on the secretory immunoglobulin A (SIgA) concentration and lysozyme activity. Forty mothers of full-term infants aged one to six months provided milk samples. The fresh samples were examined within 24 h of expression, and the other samples were stored in a refrigerator for four days or in two types of freezers for six months. The SIgA concentrations and lysozyme activity in the milk samples were studied using enzyme-linked immunosorbent assay (ELISA) kits and fluorometric lysozyme activity assay kits, respectively. The pairwise comparisons of the SIgA concentration and lysozyme activity were carried out using one-way analysis of variance with Dunnett T3 or Kruskal–Wallis tests with Bonferroni correction, depending on the data distribution. The mean temperatures of the refrigerator, upright freezer on top of the refrigerator, and deep freezer (chest freezer) were 2.0, −16.7, and −22.3 °C, respectively. Our study results highlight that the SIgA concentration and lysozyme activity of HM stored in the refrigerator for four days and in freezers for six months were significantly lower than those of fresh HM (p < 0.001). During the first six months of storage in both types of freezers, the SIgA levels were stable, whereas the lysozyme activity significantly decreased (p < 0.001). HM stored in the deep freezer had a higher SIgA concentration and lysozyme activity than HM stored in the upright freezer on top of the refrigerator. Our data support the superiority of fresh human milk over stored HM. If HM is to be stored, then storage in a deep freezer is potentially a more effective method for the preservation of SIgA concentrations and lysozyme activity than storage by refrigeration for four days or in an upright freezer on top of a refrigerator for six months. Full article
(This article belongs to the Special Issue 2nd Edition of Breast Milk and Infant Well-Being)
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