Advances in Cancer Rehabilitation

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: closed (31 January 2023) | Viewed by 4389

Special Issue Editors


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Guest Editor
Department of Rehabilitation, Greater Poland Cancer Centre, 61-866 Poznan, Poland
Interests: cancer rehabilitation; physical exercise; neurorehabilitation; biomechanics; quality of life

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Guest Editor
Faculty of Physiotherapy, Wroclaw University of Health and Sport Sciences, 35 Paderewskiego Street, 51-612 Wrocław, Poland
Interests: cancer rehabilitation; cancer prevention; physical activity; physical exercise; lymphedema
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Special Issue Information

Dear Colleagues,

Cancer diseases require particular attention due to their consequences for physical, psychological and social health. Cancer rehabilitation is a critical process of cancer care available before, during and after cancer treatment and involves many types of specialists working together to develop a personal rehabilitation plan that considers the preferences, strengths and goals of cancer patients. Cancer and oncological treatment can result in severe health problems and may be one of the leading causes of disability; however, participating in the cancer rehabilitation program may help patients experience a fuller or quicker recovery. Therefore, we are inviting the submission of papers presenting current clinical trials and implemented projects in the field of oncological rehabilitation, highlighting the progress of cancer patient rehabilitation.

Dr. Katarzyna Hojan
Dr. Iwona Malicka
Guest Editors

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Keywords

  • cancer
  • oncology
  • rehabilitation
  • physiotherapy
  • occupational therapy
  • disability
  • posture
  • quality of life
  • fatigue
  • exercise
  • pain treatment
  • supportive care

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Published Papers (2 papers)

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14 pages, 1433 KiB  
Article
Redox Status Response of Physical Exercise Training in Women with Breast Cancer during Trastuzumab Therapy
by Katarzyna Hojan, Karolina Gerreth, Danuta Procyk, Krystian Mania, Anna Zalewska and Mateusz Maciejczyk
Healthcare 2022, 10(10), 2039; https://doi.org/10.3390/healthcare10102039 - 15 Oct 2022
Cited by 3 | Viewed by 1605
Abstract
Trastuzumab is indicated in the adjuvant setting for the early and intermediate stages of breast cancer (BC) positive for epidermal growth factor receptor 2 (HER2). Although HER2 in BC patients tends to disrupt pro-oxidant and inflammatory signaling, the influence of trastuzumab in modulating [...] Read more.
Trastuzumab is indicated in the adjuvant setting for the early and intermediate stages of breast cancer (BC) positive for epidermal growth factor receptor 2 (HER2). Although HER2 in BC patients tends to disrupt pro-oxidant and inflammatory signaling, the influence of trastuzumab in modulating this process remains unknown. Due to the absence of any chemotherapeutic or chemoprophylactic agents for trastuzumab-induced side effects, this study investigated the potential role of regular physical exercise in modulating the antioxidant defenses, oxidative stress, and nitrosative damage in BC patients during trastuzumab treatment. Aim: The study aimed to analyze the relationship between regular physical activity and the redox status in women with BC during trastuzumab therapy. Materials and methods: We observed 50 BC patients during trastuzumab therapy in two groups: one that undertook moderately intensive supervised physical exercises, and a second that performed physical activity according to the recommendations for cancer patients, along with a third (control) group of healthy women. Results: The antioxidant enzyme and non-enzymatic antioxidant activities were significantly higher in the exercised group compared with the other participants. The concentrations of lipid and protein oxidative damage and nitrosative stress products were significantly higher in both BC groups than in the healthy controls. Conclusions: Trastuzumab treatment stimulates a redox response in BC patients. The results highlight the oxidative imbalance in parallel with regular physical training in women with BC during trastuzumab therapy. Further studies are needed to analyze different intensities and levels of physical training in women with BC during trastuzumab treatment. Full article
(This article belongs to the Special Issue Advances in Cancer Rehabilitation)
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14 pages, 895 KiB  
Systematic Review
Remote and Unsupervised Exercise Strategies for Improving the Physical Activity of Colorectal Cancer Patients: A Meta-Analysis
by Andrea Corazzi Pelosi, Gabriela Cerávolo Rostirola, Juliana Silva Pereira, Karen Christine Silva, Maria Eduarda Ramos Fontanari, Manoela Stahl Parisotto Oliveira, Ivan Gustavo Masselli dos Reis and Leonardo Henrique Dalcheco Messias
Healthcare 2023, 11(5), 723; https://doi.org/10.3390/healthcare11050723 - 1 Mar 2023
Cited by 7 | Viewed by 2269
Abstract
Colorectal cancer (CRC) burden across the world is expected to increase by ~2.2 million new cases and ~1.1 million deaths by 2030. Regular physical exercise is recommended to prevent CRC, but the myriad of protocols preclude further discussion on how to manage its [...] Read more.
Colorectal cancer (CRC) burden across the world is expected to increase by ~2.2 million new cases and ~1.1 million deaths by 2030. Regular physical exercise is recommended to prevent CRC, but the myriad of protocols preclude further discussion on how to manage its variables for this population. Home-based exercise guided by remote monitoring provides an alternative to surpass the barriers of supervised exercise. However, no meta-analysis was conducted to verify the effectiveness of this intervention for improving physical activity (PA). We performed a systematic review of remote and unsupervised strategies imposed on CRC patients for improving PA and compared, via a meta-analysis, their effectiveness against CRC patients submitted to usual care or no intervention. The databases PubMed, Scopus, and Web of Science were searched on 20 September 2022. Eleven studies attained the criteria for eligibility in the qualitative approach, and seven were included in the meta-analysis. No significant effect (p = 0.06) of remote and unsupervised exercise intervention was observed. However, a sensitivity analysis including three studies that only considered CRC patients was performed, demonstrating a significant effect in favor of exercise (p = 0.008). Based on our sensitivity analysis, remote and unsupervised exercise strategies were effective to improve the PA of CRC patients. Full article
(This article belongs to the Special Issue Advances in Cancer Rehabilitation)
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