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Progress in Prevention and Care for Cardiovascular Diseases: Second Edition
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Progress in Prevention and Care for Cardiovascular Diseases: Second Edition

A special issue of Healthcare (ISSN 2227-9032). This special issue belongs to the section "Chronic Care".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 3046

Special Issue Editor

Dr. Jerzy Wiliñski

E-Mail Website
Guest Editor
1. Electrotherapy and Angiology, Center for Invasive Cardiology, 33-300 Nowy Sacz, Poland
2. Department of Internal Medicine with Cardiology Subdivision, Blessed Marta Wiecka District Hospital, 32-700 Bochnia, Poland
Interests: heart failure; pulmonary embolism; heart arrhythmias; arterial hypertension; kidney diseases; echocardiography; cardiac pacing; cardiac ablation; pharmacotherapy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Collogues,

Cardiovascular diseases are the leading cause of morbidity and mortality worldwide, with a heavy burden on healthcare systems. The last few years in medicine and cardiology have been seriously affected by the COVID-19 pandemic. Now that the pandemic is over, we should come back to the bench and bedside and start creating our future straightaway. If we go back in time just 20 years, into a world without smartphones, and see what the treatment of the most common cardiovascular diseases looked like, we can appreciate the developments in technology, pharmacotherapy, and knowledge sharing. The way it will be in the forthcoming decades is utterly up to us.

To address this issue, we invite both researchers and clinicians to submit the results of their studies on cardiovascular diseases. We expect papers with significant findings, making an impact on our knowledge and the way of thinking about certain cardiovascular diseases. The ultimate goal of this Special Issue is to create a scientific environment that will be able to improve patients’ well-being and outcomes.

Thank you for considering publishing with us. We look forward to hearing from you!

Dr. Jerzy Wiliñski
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • arterial hypertension
  • heart failure
  • atrial fibrillation
  • conduction system pacing
  • cardiac resynchronization therapy
  • valvular heart disease and treatment
  • venous thromboembolic disease
  • pulmonary embolism
  • pulmonary hypertension
  • diagnostic imaging
  • echocardiography
  • prevention of cardiovascular diseases
  • oral anticoagulant therapy
  • dyslipidemia
  • atherosclerosis
  • heart arrhythmia
  • cardiac arrhythmia ablation
  • stroke
  • oncology and cardiovascular diseases
  • myocardial infarction
  • myocardial revascularization

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Related Special Issue

Published Papers (4 papers)

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Research

16 pages, 1172 KB  
Article
Frailty Syndrome and Cardiovascular Diseases in Older People
by Gabriela Cristina Chelu, Ovidiu Lucian Băjenaru, Cătălina Raluca Nuță, Lidia Băjenaru and Gabriel Ioan Prada
Healthcare 2025, 13(24), 3275; https://doi.org/10.3390/healthcare13243275 - 13 Dec 2025
Viewed by 153
Abstract
Objective: Cardiovascular diseases have a high prevalence among the elderly, together with frailty syndrome, and both conditions negatively affect quality of life and limit patient autonomy. This study aimed to explore potential relationships between cardiovascular and metabolic parameters, renal function, and frailty domains [...] Read more.
Objective: Cardiovascular diseases have a high prevalence among the elderly, together with frailty syndrome, and both conditions negatively affect quality of life and limit patient autonomy. This study aimed to explore potential relationships between cardiovascular and metabolic parameters, renal function, and frailty domains to identify potential intervention targets. Methods: A cross-sectional study was conducted between January 2024 and April 2025 at the National Institute of Gerontology and Geriatrics “Ana Aslan”, including 359 patients aged over 40 years. Demographic, anthropometric, and clinical data were collected through interviews, medical records, and standardized assessments of frailty components (weakness, exhaustion, slow gait, balance impairment, reduced activity, cognitive decline, and weight loss), as well as cardiovascular diseases and comorbidities. Results: Most participants were aged 65–79 years. ROC curve identified triglycerides as a good indicator of both alcohol consumption (AUC = 0.631, p = 0.042) and smoking status (AUC = 0.676, p = 0.004), while HDL cholesterol showed an inverse association with smoking status (AUC = 0.356, p = 0.019). Reduced renal function was significantly associated with smoking status, balance, gait impairment, and reduced functional mobility. The Up and Go Test indicated a good discriminatory ability for renal function decline (AUC = 0.656, p < 0.001). Muscle strength, MMSE, and Tinetti scores showed inverse associations with renal function. Conclusions: Renal impairment appears to be a reliable indicator across multiple frailty domains, acting as an accelerator of frailty progression. Triglycerides reflect lifestyle-related factors, while the Up and Go Test may serve as a practical screening tool for renal dysfunction in frail older adults. These findings suggest the need to adapt traditional cardiovascular risk management to the frail geriatric population. Full article
(This article belongs to the Special Issue Progress in Prevention and Care for Cardiovascular Diseases: Second Edition)
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14 pages, 376 KB  
Article
Movement-Based Mindfulness vs. Attention Control for Modifying Physiological Risk in Chronic Stroke: Evidence from a Feasibility Trial
by Tharshanah Thayabaranathan, Marina Paul, Frederick R. Walker, Shaun Hancock, Liam Allan, Maarten A. Immink, Susan Hillier, Monique F. Kilkenny, Amy Brodtmann, Emma Gee, Leeanne M. Carey, Rene Stolwyk, Julie Bernhardt, Michael Nilsson and Dominique A. Cadilhac
Healthcare 2025, 13(22), 2940; https://doi.org/10.3390/healthcare13222940 - 17 Nov 2025
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Abstract
Background: Managing physiological risk factors (blood pressure, lipids, stress, blood glucose) post-stroke is essential yet challenging. In this sub-study of a feasibility randomized controlled trial, we examined changes in these parameters following a stroke-tailored mindfulness-based intervention (MBI) compared with an attention control. [...] Read more.
Background: Managing physiological risk factors (blood pressure, lipids, stress, blood glucose) post-stroke is essential yet challenging. In this sub-study of a feasibility randomized controlled trial, we examined changes in these parameters following a stroke-tailored mindfulness-based intervention (MBI) compared with an attention control. Methods: Participants 3–18 months post-stroke were recruited from the Australian Stroke Clinical Registry (May 2021–July 2023) and randomized 1:1 to a 12-week MBI (weekly yoga + ≥3 home meditation sessions) or attention control (education and peer support). All attended weekly 60-min classes. Outcomes included blood pressure and stress (perceived stress scale, hair cortisol). A sub-group (n = 17) also had HbA1c and lipid profile assessed. Descriptive statistics, within-group effect sizes (Cohen’s d), and generalized linear modeling were used. Results: A total of 38 participants were randomized with 36 participants completing the trial (mean age 69 years; 72% male), and the MBI group showed greater within-group improvements in blood pressure, with clinically meaningful reductions in systolic (5 mmHg; d = 0.35) and diastolic (4 mmHg; d = 0.41) values, compared to smaller effects in the control group. Exploratory trends suggested favorable change in lipid profiles (HDL and LDL) in the MBI group, while triglycerides improved in the control group. No changes were observed for HbA1c. Stress markers, including hair cortisol, showed positive trends in the MBI group (d = 0.52). No significant between-group differences were detected. Conclusions: This sub-study of a well-designed, rigorous feasibility trial provides preliminary findings of clinically meaningful differences in blood pressure and lipid profiles in the MBI group. The findings support the potential of MBIs in managing post-stroke cardiovascular risk factors and warrant larger trials to confirm these preliminary effects. Full article
(This article belongs to the Special Issue Progress in Prevention and Care for Cardiovascular Diseases: Second Edition)
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8 pages, 197 KB  
Article
Various GLP-1 Receptor Agonist Preference Use with a Special Focus on Oral and Subcutaneous Forms in Poland
by Klaudia Nowak, Artur Dziewierz, Aleksandra Sojda, Michał Zabojszcz, Łukasz Szarpak, Natalia Dardzinska, Paulina Jaskulska and Zbigniew Siudak
Healthcare 2025, 13(22), 2874; https://doi.org/10.3390/healthcare13222874 - 12 Nov 2025
Viewed by 675
Abstract
Background: Since the introduction of the first GLP-1 receptor agonist (GLP-1 RA) in 2005, there has been a steady increase in the number of drugs available in this group, as well as an expansion of their indications and routes of administration. Aim [...] Read more.
Background: Since the introduction of the first GLP-1 receptor agonist (GLP-1 RA) in 2005, there has been a steady increase in the number of drugs available in this group, as well as an expansion of their indications and routes of administration. Aim: The aim of the study was to assess the clinical characteristics of patients treated with GLP-1 RA in Poland in 2018–2024, with particular emphasis on the disease entities constituting indications for treatment (like obesity and diabetes), and to analyse the frequency of use of individual drugs during the study period. Methods: A cohort study was conducted based on anonymised medical data from 300 outpatient clinics the largest private healthcare facilities in Poland (Luxmed), on consecutive patients who had at least one prescription for GLP-1 RA. The analysis covered the period from 1 January 2018 to 31 December 2024. Results: The number of patients using GLP-1 RA increased from 212 in 2018 to 12,836 in 2024. Obesity was diagnosed in 78% of all patients, most often in the groups using liraglutide and tirzepatide. The highest percentage of patients with type 2 diabetes was observed in the dulaglutide group (67%), while the lowest was in the tirzepatide group (15%). From 2022, the share of oral semaglutide steadily increased, reaching 50% of all semaglutide applications in 2024 in Poland. Conclusions: In the analysed group, GLP-1 RAs were most commonly used to treat obesity. The oral form of semaglutide was more frequently used in younger females with less aggravating medical history. Full article
(This article belongs to the Special Issue Progress in Prevention and Care for Cardiovascular Diseases: Second Edition)
11 pages, 227 KB  
Article
Blood Pressure and Blood Pressure Variability in Relation to Chronic Low Back Pain Among Patients with Hypertension
by Maciej Skrzypek, Michał Słaboszewski, Rafał Kolec, Wiktoria Wojciechowska, Agnieszka Olszanecka, Piotr Wróbel, Maciej Polak, Katarzyna Stolarz-Skrzypek and Marek W. Rajzer
Healthcare 2025, 13(10), 1166; https://doi.org/10.3390/healthcare13101166 - 16 May 2025
Viewed by 1023
Abstract
Introduction: Chronic pain which tends to be localised particularly in the lower back and lower extremities is one of the risk factors for elevated blood pressure (BP). In this cross-sectional study, we evaluated whether chronic low back pain (cLBP) is associated with BP [...] Read more.
Introduction: Chronic pain which tends to be localised particularly in the lower back and lower extremities is one of the risk factors for elevated blood pressure (BP). In this cross-sectional study, we evaluated whether chronic low back pain (cLBP) is associated with BP variability, which may be related to increased mortality and morbidity. Methods: We included 85 consecutive hypertensive patients with a median age of 62 years (IQR, 55–67) with cLBP, for which intensity was assessed using the Oswestry Disability Index (ODI). Ambulatory blood pressure monitoring (ABPM) was performed to evaluate the values and variability of systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) over 24 h, day- and nighttime BP variability assessed as BP standard deviation (SD). Results: In the whole study population, the median ODI questionnaire score was 16 (IQR, 11–20). Patients with an equal/higher than median ODI score had lower nighttime DBP compared with other patients (p = 0.028). Equal/higher than median ODI score correlated with 24 h SD values for SBP and MAP (r = 0.263; p = 0.016, and r = 0.229; p = 0.036, respectively), as well as with day–night differences in SBP (r = 0.229; p = 0.035), DBP (r = 0.253; p = 0.019), and MAP (r = 0.263; p = 0.015). We performed a multivariate regression analysis adjusted for potential confounders, and equal/higher than median ODI score was predicted by age (OR, 1.07; 95% CI, 1.006–1.14; p = 0.031) and day–night DBP difference (OR 1.07; 95% CI 1.002–1.15; p = 0.044). Conclusions: To our knowledge, this is the first study to show that more intense cLBP is associated with BP variability among patients with hypertension. Full article
(This article belongs to the Special Issue Progress in Prevention and Care for Cardiovascular Diseases: Second Edition)
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