Blood Pressure and Blood Pressure Variability in Relation to Chronic Low Back Pain Among Patients with Hypertension

Skrzypek, Maciej; Słaboszewski, Michał; Kolec, Rafał; Wojciechowska, Wiktoria; Olszanecka, Agnieszka; Wróbel, Piotr; Polak, Maciej; Stolarz-Skrzypek, Katarzyna; Rajzer, Marek W.

doi:10.3390/healthcare13101166

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Blood Pressure and Blood Pressure Variability in Relation to Chronic Low Back Pain Among Patients with Hypertension

by

Maciej Skrzypek

^1,†,

Michał Słaboszewski

^2,†,

Rafał Kolec

²,

Wiktoria Wojciechowska

³,

Agnieszka Olszanecka

³,

Piotr Wróbel

¹,

Maciej Polak

⁴

,

Katarzyna Stolarz-Skrzypek

^3,*

and

Marek W. Rajzer

³

¹

Department of Medicine and Health Sciences, Andrzej Frycz Modrzewski Krakow University, 30-705 Kraków, Poland

²

Students Scientific Group, First Department of Cardiology, Interventional Electrocardiology and Hypertension, Faculty of Medicine, Jagiellonian University Medical College, 31-008 Kraków, Poland

³

First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, 30-688 Kraków, Poland

⁴

Department of Epidemiology and Population Studies, Institute of Public Health, Jagiellonian University Medical College, 31-066 Kraków, Poland

^*

Author to whom correspondence should be addressed.

^†

These authors contributed equally to this work.

Healthcare 2025, 13(10), 1166; https://doi.org/10.3390/healthcare13101166

Submission received: 3 April 2025 / Revised: 13 May 2025 / Accepted: 14 May 2025 / Published: 16 May 2025

(This article belongs to the Special Issue Progress in Prevention and Care for Cardiovascular Diseases: Second Edition)

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Abstract

Introduction: Chronic pain which tends to be localised particularly in the lower back and lower extremities is one of the risk factors for elevated blood pressure (BP). In this cross-sectional study, we evaluated whether chronic low back pain (cLBP) is associated with BP variability, which may be related to increased mortality and morbidity. Methods: We included 85 consecutive hypertensive patients with a median age of 62 years (IQR, 55–67) with cLBP, for which intensity was assessed using the Oswestry Disability Index (ODI). Ambulatory blood pressure monitoring (ABPM) was performed to evaluate the values and variability of systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) over 24 h, day- and nighttime BP variability assessed as BP standard deviation (SD). Results: In the whole study population, the median ODI questionnaire score was 16 (IQR, 11–20). Patients with an equal/higher than median ODI score had lower nighttime DBP compared with other patients (p = 0.028). Equal/higher than median ODI score correlated with 24 h SD values for SBP and MAP (r = 0.263; p = 0.016, and r = 0.229; p = 0.036, respectively), as well as with day–night differences in SBP (r = 0.229; p = 0.035), DBP (r = 0.253; p = 0.019), and MAP (r = 0.263; p = 0.015). We performed a multivariate regression analysis adjusted for potential confounders, and equal/higher than median ODI score was predicted by age (OR, 1.07; 95% CI, 1.006–1.14; p = 0.031) and day–night DBP difference (OR 1.07; 95% CI 1.002–1.15; p = 0.044). Conclusions: To our knowledge, this is the first study to show that more intense cLBP is associated with BP variability among patients with hypertension.

Keywords: Oswestry Disability Index; chronic low back pain; blood pressure variability; hypertension; ambulatory blood pressure

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MDPI and ACS Style

Skrzypek, M.; Słaboszewski, M.; Kolec, R.; Wojciechowska, W.; Olszanecka, A.; Wróbel, P.; Polak, M.; Stolarz-Skrzypek, K.; Rajzer, M.W. Blood Pressure and Blood Pressure Variability in Relation to Chronic Low Back Pain Among Patients with Hypertension. Healthcare 2025, 13, 1166. https://doi.org/10.3390/healthcare13101166

AMA Style

Skrzypek M, Słaboszewski M, Kolec R, Wojciechowska W, Olszanecka A, Wróbel P, Polak M, Stolarz-Skrzypek K, Rajzer MW. Blood Pressure and Blood Pressure Variability in Relation to Chronic Low Back Pain Among Patients with Hypertension. Healthcare. 2025; 13(10):1166. https://doi.org/10.3390/healthcare13101166

Chicago/Turabian Style

Skrzypek, Maciej, Michał Słaboszewski, Rafał Kolec, Wiktoria Wojciechowska, Agnieszka Olszanecka, Piotr Wróbel, Maciej Polak, Katarzyna Stolarz-Skrzypek, and Marek W. Rajzer. 2025. "Blood Pressure and Blood Pressure Variability in Relation to Chronic Low Back Pain Among Patients with Hypertension" Healthcare 13, no. 10: 1166. https://doi.org/10.3390/healthcare13101166

APA Style

Skrzypek, M., Słaboszewski, M., Kolec, R., Wojciechowska, W., Olszanecka, A., Wróbel, P., Polak, M., Stolarz-Skrzypek, K., & Rajzer, M. W. (2025). Blood Pressure and Blood Pressure Variability in Relation to Chronic Low Back Pain Among Patients with Hypertension. Healthcare, 13(10), 1166. https://doi.org/10.3390/healthcare13101166

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Blood Pressure and Blood Pressure Variability in Relation to Chronic Low Back Pain Among Patients with Hypertension

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