Collaborative Approaches to Risk Management and Infection Control: A Patient Perspective

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: 31 May 2026 | Viewed by 2117

Special Issue Editors


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Guest Editor
School of Public Health, Vita-Salute S. Raffaele University, 20144 Milan, Italy
Interests: health management; risk management; infection prevention and control; public health; health policy

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Guest Editor
Maria Beatrice Hospital, GVM Care & Research, via Manzoni 12, 50121 Firenze, Italy
Interests: forensic medicine; legal medicine; health regulation; risk management; infection prevention and control

Special Issue Information

Dear Colleagues,

In recent years, the fields of risk management and infection prevention and control have become more critical than ever due to global health challenges within a globalized ecosystem, such as the COVID-19 pandemic, antimicrobial resistance, and evolving healthcare-associated infections.

Healthcare-associated infections, with intra-hospital falls and medication errors, are the more frequent adverse events that trigger patient safety and hospital reliability.

Effective infection prevention and control policies, together with robust risk management strategies, help mitigate the impact of those threats, enhancing resilience within healthcare services. At the same time, innovation in the healthcare sector is confronted with a stringent regulatory framework. This research area holds immense significance as it seeks to address these critical issues through innovative approaches, advanced technologies, and multidisciplinary collaboration.

We are pleased to invite you to contribute to this Special Issue focused on “Collaborative Approaches to Risk Management and Infection Control: A Patient Perspective” to help expand our collective understanding and develop actionable insights that can transform healthcare practices.

This Special Issue aims to gather cutting-edge and patient-centered research and reviews that explore advancements, strategies, and best practices in risk management and infection prevention within healthcare settings. By addressing risk assessment, infection control policies, and the integration of novel technologies, this issue will highlight solutions to contemporary challenges and offer insights into future trends in the field. The issue also emphasizes how collaborative practices—ranging from patient education initiatives to shared decision-making frameworks—can lead to improved patient outcomes. The subject aligns with the journal’s scope by focusing on innovative interventions, evidence-based practices, and emerging paradigms relevant to patient safety and public health risk management.

In this Special Issue, we welcome original research articles, comprehensive reviews, and commentaries. Research areas may include (but are not limited to) the following themes:

  • Strategies for infection prevention and control in healthcare settings;
  • Risk assessment and management frameworks for infection control and other adverse events;
  • Impact of antimicrobial resistance on infection prevention practices;
  • Role of emerging technologies, including AI and machine learning, in infection risk management or other adverse events;
  • New tools and research on incident reporting and HAI reporting;
  • Psychological and organizational factors affecting protocol adherence, in particular for HAI;
  • Case studies on outbreak management, containment measures, and risk control strategies;
  • Policy development and implementation for effective risk prevention and patient safety.

We look forward to receiving your contributions that will deepen the collective understanding of these essential topics and provide guidance for healthcare professionals and policymakers.

We look forward to receiving your contributions.

Dr. Lorenzo Blandi
Dr. Vittorio Bolcato
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • risk management
  • risk assessment
  • risk reduction behavior
  • infection control
  • infection prevention
  • healthcare-associated infections
  • preventive health services

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Published Papers (3 papers)

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Research

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10 pages, 215 KB  
Communication
Rapid Response and Containment of an NDM-Producing Klebsiella Pneumoniae Outbreak in a Hematology Ward: Case Study from an Italian Hospital
by Ilaria Tocco Tussardi, Gloria Stevanin, Livio Montesarchio, Francesca Palladini, Irene Aprili, Emanuela Zandonà, Cristina Tecchio and Stefano Tardivo
Healthcare 2025, 13(12), 1457; https://doi.org/10.3390/healthcare13121457 - 17 Jun 2025
Viewed by 515
Abstract
Antimicrobial resistance (AMR) constitutes a critical threat to global public health, with carbapenem-resistant Enterobacterales (CRE) presenting significant challenges due to their resistance to last-line antibiotics. Among these, New Delhi metallo-beta-lactamase (NDM)-producing Klebsiella pneumoniae (KP) is of particular concern. This study describes an outbreak [...] Read more.
Antimicrobial resistance (AMR) constitutes a critical threat to global public health, with carbapenem-resistant Enterobacterales (CRE) presenting significant challenges due to their resistance to last-line antibiotics. Among these, New Delhi metallo-beta-lactamase (NDM)-producing Klebsiella pneumoniae (KP) is of particular concern. This study describes an outbreak of NDM-producing KP in the hematology unit of the University Hospital of Verona, Italy. This represents the second reported hospital outbreak of this strain in Italy, and the first to occur within a hematology ward. The outbreak involved four patients, all of whom were identified through active surveillance and microbiological screening. In response, a multidisciplinary team implemented a series of infection prevention and control (IPC) measures, which included enhanced environmental cleaning, strict hand hygiene protocols, patient isolation, and the development of a tailored IPC checklist. The outbreak was effectively contained within three weeks following the identification of the last case. This outcome underscores the importance of rapid and coordinated responses to NDM-producing KP outbreaks. This case study emphasizes the necessity of robust IPC protocols, rapid intervention, and continuous staff education in mitigating the spread of multidrug-resistant pathogens in healthcare settings. It further highlights the urgent need for healthcare systems to be adequately prepared and resilient in addressing the growing threat of AMR. Full article

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11 pages, 327 KB  
Commentary
Preventive Healthcare and Disability: Challenges and Opportunities
by Giovanni Emanuele Ricciardi, Rita Cuciniello, Veronica Raimondi, Francesco Vaia, Carlo Signorelli and Cristina Renzi
Healthcare 2025, 13(17), 2099; https://doi.org/10.3390/healthcare13172099 - 23 Aug 2025
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Abstract
Despite global commitments to universal health coverage, persons with disabilities (PwD) continue to face significant barriers in accessing appropriate healthcare, including diagnostics, treatments and preventive healthcare, with lower participation in cancer screening and vaccination programs. These disparities are driven by diverse, intersecting obstacles [...] Read more.
Despite global commitments to universal health coverage, persons with disabilities (PwD) continue to face significant barriers in accessing appropriate healthcare, including diagnostics, treatments and preventive healthcare, with lower participation in cancer screening and vaccination programs. These disparities are driven by diverse, intersecting obstacles (structural, financial, communicative, and social) that vary by disability type and context. Inclusive approaches, co-designed with PwD and supported by standardized assessment tools, are urgently needed to address persistent inequities in healthcare access and outcomes. Full article
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39 pages, 1706 KB  
Systematic Review
Improving Vaccine Coverage Among Older Adults and High-Risk Patients: A Systematic Review and Meta-Analysis of Hospital-Based Strategies
by Flavia Pennisi, Stefania Borlini, Rita Cuciniello, Anna Carole D’Amelio, Rosaria Calabretta, Antonio Pinto and Carlo Signorelli
Healthcare 2025, 13(14), 1667; https://doi.org/10.3390/healthcare13141667 - 10 Jul 2025
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Abstract
Background/Objectives: Adult vaccination remains suboptimal, particularly among older adults and individuals with chronic conditions. Hospitals represent a strategic setting for improving vaccination coverage among these high-risk populations. This systematic review and meta-analysis evaluated hospital-based interventions aimed at enhancing vaccine uptake in adults aged [...] Read more.
Background/Objectives: Adult vaccination remains suboptimal, particularly among older adults and individuals with chronic conditions. Hospitals represent a strategic setting for improving vaccination coverage among these high-risk populations. This systematic review and meta-analysis evaluated hospital-based interventions aimed at enhancing vaccine uptake in adults aged ≥60 years or 18–64 years with at-risk medical conditions. Methods: We conducted a systematic review and meta-analysis following PRISMA and MOOSE guidelines. Searches in PubMed, EMBASE, and Scopus identified studies published in the last 10 years evaluating hospital-based interventions reporting vaccination uptake. The risk of bias was assessed using validated tools (NOS, RoB 2, ROBINS-I, QI-MQCS). A meta-analysis was conducted for categories with ≥3 eligible studies reporting pre- and post-intervention vaccination coverage in the same population. Results: We included 44 studies. Multi-component strategies (n = 21) showed the most consistent results (e.g., pneumococcal uptake from 2.2% to 43.4%, p < 0.001). Reminder-based interventions (n = 4) achieved influenza coverage increases from 31.0% to 68.0% and a COVID-19 booster uptake boost of +38% after SMS reminders. Educational strategies (n = 11) varied in effectiveness, with one study reporting influenza coverage rising from 1.6% to 12.2% (+662.5%, OR 8.86, p < 0.01). Standing order protocols increased pneumococcal vaccination from 10% to 60% in high-risk adults. Hospital-based catch-up programs improved DTaP-IPV uptake from 56.2% to 80.8% (p < 0.001). For patient education, the pooled OR was 2.11 (95% CI: 1.96–2.27; p < 0.001, I2 = 97.2%) under a fixed-effects model, and 2.47 (95% CI: 1.53–3.98; p < 0.001) under a random-effects model. For multi-component strategies, the OR was 2.39 (95% CI: 2.33–2.44; p < 0.001, I2 = 98.0%) with fixed effects, and 3.12 (95% CI: 2.49–3.92; p < 0.001) with random effects. No publication bias was detected. Conclusions: Hospital-based interventions, particularly those using multi-component approaches, effectively improve vaccine coverage in older and high-risk adults. Embedding vaccination into routine hospital care offers a scalable opportunity to reduce disparities and enhance population-level protection. Future policies should prioritize the institutional integration of such strategies to support healthy aging and vaccine equity. Full article
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